Basic Information

Gene Symbol
-
Assembly
GCA_030068185.1
Location
JASGYR010000261.1:4794576-4795706[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.13 15 7.1 0.0 2 23 47 68 46 68 0.96
2 10 1.9e-05 0.0023 19.1 1.6 2 23 81 102 80 102 0.95
3 10 4.2e-05 0.0051 18.0 1.2 1 23 108 130 108 130 0.98
4 10 0.00076 0.09 14.1 0.2 1 23 136 159 136 159 0.95
5 10 0.00011 0.013 16.7 0.6 1 23 165 187 165 187 0.97
6 10 0.00019 0.022 16.0 5.2 1 23 198 220 198 220 0.97
7 10 2.5e-07 3e-05 25.0 0.2 1 23 229 251 229 251 0.99
8 10 2.4e-06 0.00028 21.9 1.1 1 23 257 279 257 279 0.98
9 10 1.9e-05 0.0023 19.1 5.3 1 23 285 307 285 307 0.98
10 10 2.5e-06 0.0003 21.9 3.8 1 23 313 335 313 335 0.98

Sequence Information

Coding Sequence
ATGATGCCTCAGGATCAGCAGCAATGCGGGCCCAACGAGATATTCGATCAGGAAGACACAGAGCAGCTGCTCATCACAGATAGTTCACACATATCGAATGTGGCGAGCGCGGAGATAATCATCTCCGAGGGTATCGTGCAGTGCAGTCTCTGCGGAGATGGTTTCGTTTCCGAACAAGCTCTTGGATTGCATTTAGAGATGCACGAGCAGAGTAACGCTCAATTGGACGACGACCAGCTTGTTTGCGAACATTGCGGTTGTAGTTTTGCCACGACATCCGCGTTGAAGGAGCATCAGTTAGAGCACGAGACGGACGAGAGTCACACCTGCGAAACGTGTGGCTACGTCACAACGCGCAAAGAGGTTCTGATTGCTCATCAGAAACGGCACAATGTCGAGTACAAATACGAGTGCGAGATCTGCGGCGACAGTTTCGTCTCGCGTATCAGTTACCAGGAACACCAGTCGCTCCAACACGCCAACGAAAAGCCCTTTCAATGCGAGATTTGCAACGCCACGTTCCGCTATCGTCAAGGTCTGAGGTTGCACGGGAAATTGCATCAGCCTGACTACGTGCCGCCGCAGAGGAAGCATCATTGCGTGCTTTGCAACAAACGTTTCTCCAGGAAGCAGGTGTTGCTCGTACACATGAAGACGCACGGGAACGTGGGACCCCAGAACGAGTACGTGTGCCCGGTTTGTGGCAAGGCGGTCTCCAGTAAGACCTACCTGACCGTTCATCTGCGCAAGCACACCGGCGAAAAGCCCCACGTTTGCGATCTCTGCGGCAAGGGATTCATTTCGCAGAATTATCTGAGCGTTCACAGACGCACGCACACGGGCGAACGACCGCACAAATGCACCCACTGCGAGAAACGATTCACACAACGAACCACACTGGTGGTGCATCTAAGGGGTCACACGGGCGATCGACCCTATCCGTGCACGTTCTGTCACAAATCGTTCGCCTCGAAAACGATGCTTAACTCGCACCTGAAAACTCACGCGAAGCAAAGCGCTAGGCAACAACAggaacaacaacagcagcagcaacagcagctaCAGCAGGAACCAGAGGTCCAGCACGAAGAACAATCCCTCGACACTATAACTATATTATTACCTAGTTAG
Protein Sequence
MMPQDQQQCGPNEIFDQEDTEQLLITDSSHISNVASAEIIISEGIVQCSLCGDGFVSEQALGLHLEMHEQSNAQLDDDQLVCEHCGCSFATTSALKEHQLEHETDESHTCETCGYVTTRKEVLIAHQKRHNVEYKYECEICGDSFVSRISYQEHQSLQHANEKPFQCEICNATFRYRQGLRLHGKLHQPDYVPPQRKHHCVLCNKRFSRKQVLLVHMKTHGNVGPQNEYVCPVCGKAVSSKTYLTVHLRKHTGEKPHVCDLCGKGFISQNYLSVHRRTHTGERPHKCTHCEKRFTQRTTLVVHLRGHTGDRPYPCTFCHKSFASKTMLNSHLKTHAKQSARQQQEQQQQQQQQLQQEPEVQHEEQSLDTITILLPS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00118162;
90% Identity
-
80% Identity
-