Basic Information

Gene Symbol
-
Assembly
GCA_958295455.1
Location
OY282416.1:865096-866700[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.059 6.8 8.6 0.6 2 20 163 181 162 185 0.89
2 10 1.1 1.3e+02 4.6 1.0 1 23 191 213 191 213 0.84
3 10 0.013 1.5 10.6 0.1 2 23 220 241 219 241 0.96
4 10 0.0039 0.45 12.3 0.1 1 20 246 265 246 267 0.93
5 10 4.6e-05 0.0053 18.4 2.8 2 23 291 312 290 312 0.96
6 10 0.00076 0.088 14.5 2.3 1 23 319 341 319 341 0.97
7 10 7.1e-06 0.00082 20.9 0.7 1 23 347 369 347 369 0.96
8 10 0.00029 0.033 15.8 2.0 1 23 375 397 375 397 0.96
9 10 0.005 0.58 11.9 4.9 1 23 403 425 403 425 0.97
10 10 2.7e-06 0.00031 22.3 1.4 1 23 431 454 431 454 0.98

Sequence Information

Coding Sequence
ATGGATTCTGTGGACCACGGCTACTGCAGATTATGCGCTGCGTTAAAACCACATAACAAGTTGATAAATCTGCAAGTTGACCATGATAAACGCCATGATATACTCGAAAAGCTGTCACGAATCAACGCTGCTGCCGATTTTAATGACGAAATTCTACCGAAAACAGTGTGTTTTGTTTGTACGAGCACCTTGGACAGGGCCTTTGAGTTCGTTCTCGGGATAGACCAAGCGCAGGGGGAGCTACACAACCTAATTTTGCTTCAACAAATCAAGAAAGAGTCCCCGGAAGATTTGGATTTCTCTGACGACAATTTCAACTTCGAACCAACTGACGATATAAAAGATGAAAACGTAAACGTGAAACTCGAAACTGAAATTGATTCAACGCCTGTTAAAACTAAAACGCCGAAGAAACACCTATCCAAAACATGCCTTGATACGATACCACTTTCAGAACTAAAACGTACATGGAAAGATTATAGTTGGAAGTGCACAAACTGTGAAACACTGTTTGCTAACTTTGACGAGTTGAAAACTCATTCGGTACAGTATCACAATATTTGCAATGCTTTTCGGTGCACTGATTGCAATATTAGGAAGCTTCGGCTGGATAGTTTTCTAATTCACGTTAGAAGACACAGGAAGTACCTGAAACTGTCGTGTTACAAATGTAATGCTAGATTTCCTTCACCGTATGAAGCTAATGCACATCGGTCGGTGCATAAAACTACGGATCACATATGCCCTGGATGCAATGCGGAGTTTCAAAACGCAGATGAACTGAATCAACACACATCGGAATACTATCAAGTATCAAAACGGAAACCAGCTCCACCGCTCCCCTTAGCAGAGGGTATTACGGATAATTTAACATGTTTATTATGCAAAAAGACTTTCAAACACAAAGGCAGTTTAAATACACATCTCCTTATACATACAGAGAGAAAACGGGACCATACGTGTGATAAATGCGGAAAATGCTTCCTAAATAAAGCAACGTTAGCTGGCCATATAATGTTACATGATAACGTAAGACCATTCCAATgtgaaatatgtaaattttcaTTCAAAACTCAAGCGCAGCTCCGCAGCCATGTTGGTGTACATGATAATAAAAAGCCATTTGCATGTGACCAGTGTGGCCGCTGCTTCAGACTTTTACGACAATTAACGTCGCACAAAATCATCCACACAGACTCTTTGCCCCACGTTTGTTCATTTTGCAACAAACGGTTTAgatttaaaactattttgaacCAACACATACGCCAACATACTGGTGTAAAACCATATTCGTGTGATGTATGTCAGCGTGACTTCACTAACTGGCCGAATTATAATAAGCACATGAAGAGGCGACATGGTATGGATATGGCAAAGAAGAAGCATACGCCAGATGGGCTTTGTCCTATAAATCCTACTACTGGAGAAGTTATAATGTTACCGCAGAACAACAAGATTCAGGAATGGAAGGAGGAAATGATGAGGCGGAAGAGGCCTGGTAGACCACGAGTCTCTATTGCAGATGAAACGGACActggaaataataatttaagtttAAACGTTGATAACCAAGCTTTTCAAAGTACCGAATCAAATATTTAA
Protein Sequence
MDSVDHGYCRLCAALKPHNKLINLQVDHDKRHDILEKLSRINAAADFNDEILPKTVCFVCTSTLDRAFEFVLGIDQAQGELHNLILLQQIKKESPEDLDFSDDNFNFEPTDDIKDENVNVKLETEIDSTPVKTKTPKKHLSKTCLDTIPLSELKRTWKDYSWKCTNCETLFANFDELKTHSVQYHNICNAFRCTDCNIRKLRLDSFLIHVRRHRKYLKLSCYKCNARFPSPYEANAHRSVHKTTDHICPGCNAEFQNADELNQHTSEYYQVSKRKPAPPLPLAEGITDNLTCLLCKKTFKHKGSLNTHLLIHTERKRDHTCDKCGKCFLNKATLAGHIMLHDNVRPFQCEICKFSFKTQAQLRSHVGVHDNKKPFACDQCGRCFRLLRQLTSHKIIHTDSLPHVCSFCNKRFRFKTILNQHIRQHTGVKPYSCDVCQRDFTNWPNYNKHMKRRHGMDMAKKKHTPDGLCPINPTTGEVIMLPQNNKIQEWKEEMMRRKRPGRPRVSIADETDTGNNNLSLNVDNQAFQSTESNI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00356734;
90% Identity
-
80% Identity
-