Basic Information

Gene Symbol
Sall1
Assembly
GCA_958295455.1
Location
OY282416.1:2043485-2056524[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.013 1.5 10.6 2.9 2 23 265 286 264 287 0.94
2 17 0.0027 0.31 12.8 6.5 1 23 295 317 295 317 0.99
3 17 0.0016 0.18 13.5 1.4 1 23 325 348 325 348 0.94
4 17 0.0022 0.26 13.1 0.7 1 23 354 376 354 376 0.97
5 17 1.9e-06 0.00022 22.7 2.0 1 23 382 404 382 404 0.98
6 17 1.6e-07 1.9e-05 26.1 0.8 1 23 410 432 410 432 0.96
7 17 6.6e-07 7.6e-05 24.2 0.5 1 23 438 460 438 460 0.99
8 17 1.7e-05 0.002 19.7 0.2 1 23 466 488 466 488 0.98
9 17 0.00014 0.016 16.9 0.2 1 23 494 516 494 516 0.98
10 17 6.7e-05 0.0077 17.8 2.2 1 21 522 542 522 544 0.96
11 17 0.0025 0.29 12.9 0.3 6 23 554 571 550 571 0.97
12 17 1.6e-07 1.9e-05 26.1 0.8 1 23 593 615 593 615 0.96
13 17 6.6e-07 7.6e-05 24.2 0.5 1 23 621 643 621 643 0.99
14 17 1.7e-05 0.002 19.7 0.2 1 23 649 671 649 671 0.98
15 17 0.00014 0.016 16.9 0.2 1 23 677 699 677 699 0.98
16 17 6.7e-05 0.0077 17.8 2.2 1 21 705 725 705 727 0.96
17 17 0.0025 0.29 12.9 0.3 6 23 737 754 733 754 0.97

Sequence Information

Coding Sequence
ATGGAAATGGAAGAAGACATAAAACCGCCTGTGGACAAGATTTGCCGTACATGTTTATCAAAATCTTCTGATATGAGATCTTTAGATGACATTATTGAAGGTGATCAAAGAACGTTACTGGAAGCTCTTGTTTTTGTATGTAATTTGGACATAAAAACTAGTGATAAACTACCGAGGCAAGTTTGCAGTGATTGTGAAGCCATTATGTGCAAAGCAGACGCATTCAAGAGGCGGTGTCTGGAGGCCGAATCCTTCCTTTACCTCCAGTATGGAATGGATCACACTGTCTCATCGGAAGTTGAAAATGAAGAAAAACCAGTAATAAAACCCgagaaaacttttaaaaaaccgAAATCTGTTAAATCTAATGGCAGGAAATCTTCAGTGTCGAagaaaaagtcaataaaaagtGTTGTAGATGTCCTCATTCCCGAATATAAAGATGAAAATTTTGAACCTGTAGAAATACCACTTATAACCAGTTCAAACTGTGTTGATGATGCTTCTGTGAATGTTGATGATGCTAAAGATGTAGCTGTCAAAGAGGAGATAACAAACGATTTTGATGCAGACATAGATTTTGGCTACCATCTAGATTTTAAgcaagaaaatacaaatttcactgaaatgaaaatgtttacGTGCAGTTGCGAATCAATTTTCAATAATGAAGATGAATATAAAACACATTTAGAAACAAACAGCTGTGCGGGCTATACAaaatcaatgaaaataaaatttgaaaagcgcAACTCTTTAGGTGGTAGAAATAttactattaaaaaatcaataatgTGTCCTGAGTGTGATATAGAGTTTGACACGTTAAAGAGTTGTAAATTACACCAGCGAACACACCATAAGCTTGACGAAAATTATGAATTTCAATGTACACTTTGCATGAGAAAGTTCTGTAGGAAATCTTCTTACACTGCCCATTTGAAAAAACATGAAGAACGATCAAAAATGAAGTATGTTTGTGATACATGCAAAAGAGAATTCCAACATCGAGCACATCTAGACAATCACATTATTGCTGTACATACCAGAGATAAGGGATTTACATGCGAAGTTTGCTATATGAAGTTTGCAACGGAACAGAGTTTGGAAACGCATAAGGAAAGTCATAAAACAGAGAAGAAACATCAATGTGATATTTGCAATAAGGCTTTTTATATGTTGTCTACGTTGAATGATCATATGAGAACACACACAGGAGAAAGGCCGTTCCTATGTTCTATTTGTGGACGAGGTTTCAGTCAGAAGACAAATCTGGCTCAACACATGAGGAGGCACCAGGGTCTGAAGCCGTTTAAATGTGAAGACTGTGATAGAAGATTTGTCTCAAAAGGCGAACTTGTAGCCCACACGCGGAAACACAGCGGAGCGCACCCGTTCGTGTGCGACGCATGCGGCGGTGGTTTCACTACGAGCAGCTCTCTGGCCAAACACCGGAGAACTCATACCGGTGAACGTCCTTACGCCTGTGACCTGTGCCCCATGAGGTTCGCTGCATCAGGAACACTTAAAAACCATCGAAGGACTCACACCGGAGAAAAACCATTTCAATGCTCGTACTGTGAGAAAGCTTTCGTCCAACGACAGGACCTAATCTCCCATATACGGTGTCATACGGGCGAGAGGCCGTACTCTTGTAGCTGTGGCCAGTCTTTCAGGAAGGCTGCAGCGCTCAAAGCACACGCTAAGACTCACACGCATCCAGTTGTGAGTCAGAGTCAGCCGCAAACTGTAACTCCTTGTTTGAGAGAAAGGCCGTTCCTATGTTCTATTTGTGGACGAGGTTTCAGTCAGAAGACAAATCTGGCTCAACACATGAGGAGGCACCAGGGTCTGAAGCCGTTTAAATGTGAAGACTGTGATAGAAGATTCGTCTCAAAAGGTGAACTTGTAGCCCACACGCGGAAACACAGCGGAGCGCACCCGTTCGTGTGCGACGCATGCGGCGGTGGTTTCACTACGAGCAGCTCTCTGGCCAAACACCGGAGAACTCATACCGGTGAACGTCCTTACGCCTGTGACCTGTGCCCCATGAGGTTCGCTGCATCAGGAACACTTAAAAACCATCGAAGGACTCACACCGGAGAAAAACCATTTCAATGCTCGTACTGTGAGAAAGCTTTCGTCCAACGACAGGACCTAATCTCCCATATACGGTGTCATACGGGCGAGAGGCCGTACTCTTGTAGCTGTGGCCAGTCTTTCAGGAAGGCTGCAGCGCTCAAAGCACACGCTAAGACTCACACGCATCCAGTTGTGAGTCAGACTCAGCCGCAAACTGTAACTCCTTGTTTGAGTTAA
Protein Sequence
MEMEEDIKPPVDKICRTCLSKSSDMRSLDDIIEGDQRTLLEALVFVCNLDIKTSDKLPRQVCSDCEAIMCKADAFKRRCLEAESFLYLQYGMDHTVSSEVENEEKPVIKPEKTFKKPKSVKSNGRKSSVSKKKSIKSVVDVLIPEYKDENFEPVEIPLITSSNCVDDASVNVDDAKDVAVKEEITNDFDADIDFGYHLDFKQENTNFTEMKMFTCSCESIFNNEDEYKTHLETNSCAGYTKSMKIKFEKRNSLGGRNITIKKSIMCPECDIEFDTLKSCKLHQRTHHKLDENYEFQCTLCMRKFCRKSSYTAHLKKHEERSKMKYVCDTCKREFQHRAHLDNHIIAVHTRDKGFTCEVCYMKFATEQSLETHKESHKTEKKHQCDICNKAFYMLSTLNDHMRTHTGERPFLCSICGRGFSQKTNLAQHMRRHQGLKPFKCEDCDRRFVSKGELVAHTRKHSGAHPFVCDACGGGFTTSSSLAKHRRTHTGERPYACDLCPMRFAASGTLKNHRRTHTGEKPFQCSYCEKAFVQRQDLISHIRCHTGERPYSCSCGQSFRKAAALKAHAKTHTHPVVSQSQPQTVTPCLRERPFLCSICGRGFSQKTNLAQHMRRHQGLKPFKCEDCDRRFVSKGELVAHTRKHSGAHPFVCDACGGGFTTSSSLAKHRRTHTGERPYACDLCPMRFAASGTLKNHRRTHTGEKPFQCSYCEKAFVQRQDLISHIRCHTGERPYSCSCGQSFRKAAALKAHAKTHTHPVVSQTQPQTVTPCLS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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