Carc005353.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Coenonympha arcania
Gene Symbol
NR2E3
Assembly
GCA_036785405.1
Location
CM072059.1:12434697-12467756[+]

Transcription Factor Domain

TF Family
RXR-like
Domain
zf-C4|RXR-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
DNA-binding domain of retinoid X receptor (RXR) is composed of two C4-type zinc fingers. Each zinc finger contains a group of four Cys residues which co-ordinates a single zinc atom. RXR functions as a DNA binding partner by forming heterodimers with other nuclear receptors including CAR, FXR, LXR, PPAR, PXR, RAR, TR, and VDR. All RXR heterodimers preferentially bind response elements composed of direct repeats of two AGGTCA sites with a 1-5 bp spacer. RXRs can play different roles in these heterodimers. RXR acts either as a structural component of the heterodimer complex, required for DNA binding but not acting as a receptor, or as both a structural and a functional component of the heterodimer, allowing 9-cis RA to signal through the corresponding heterodimer. In addition, RXR can also form homodimers, functioning as a receptor for 9-cis RA, independently of other nuclear receptors. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, RXR has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [cite:PUB00121610], [cite:PUB00121611], [cite:PUB00121612], [cite:PUB00025660], [cite:PUB00121613], [cite:PUB00092048], [cite:PUB00092725], [cite:PUB00092726], [cite:PUB00016724], [cite:PUB00059514PMID:18971932
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 24 3.4e-31 7.5e-28 98.6 0.5 2 115 251 356 250 368 0.90
2 24 1.2e-07 0.00026 21.7 0.0 80 115 370 405 360 417 0.87
3 24 1.1e-07 0.00024 21.8 0.0 79 115 418 454 406 466 0.86
4 24 1.1e-07 0.00023 21.9 0.0 80 115 468 503 456 516 0.86
5 24 1.2e-07 0.00026 21.7 0.0 80 115 517 552 504 564 0.86
6 24 1.1e-07 0.00025 21.8 0.0 80 115 566 601 554 613 0.87
7 24 1.5e-07 0.00032 21.4 0.0 80 115 615 650 603 653 0.88
8 24 1.7e-07 0.00037 21.2 0.0 79 115 663 699 651 711 0.86
9 24 1.1e-07 0.00024 21.8 0.0 80 115 713 748 701 761 0.86
10 24 1.1e-07 0.00024 21.8 0.0 79 115 761 797 749 809 0.86
11 24 1.1e-07 0.00024 21.8 0.0 79 115 810 846 798 858 0.86
12 24 1.2e-07 0.00026 21.7 0.0 80 115 860 895 850 907 0.87
13 24 2.3e-07 0.00051 20.8 0.0 80 115 909 944 897 956 0.87
14 24 2e-07 0.00043 21.0 0.0 80 115 958 993 946 1005 0.86
15 24 1.1e-07 0.00024 21.8 0.0 80 115 1007 1042 996 1054 0.86
16 24 1.1e-07 0.00024 21.8 0.0 80 115 1056 1091 1044 1104 0.86
17 24 4.5e-07 0.00099 19.8 0.0 80 115 1105 1140 1093 1152 0.86
18 24 3.1e-05 0.067 13.8 0.0 80 117 1154 1191 1141 1203 0.84
19 24 3.4e-07 0.00074 20.2 0.0 82 115 1205 1238 1194 1252 0.84
20 24 3.4e-05 0.075 13.7 0.0 80 116 1252 1288 1240 1299 0.85
21 24 3.7e-07 0.00082 20.1 0.0 82 115 1303 1336 1291 1347 0.86
22 24 1.2e-07 0.00026 21.7 0.0 80 115 1350 1385 1338 1397 0.86
23 24 2.9e-05 0.063 13.9 0.0 80 117 1399 1436 1387 1450 0.83
24 24 9.1e-32 2e-28 100.4 0.0 82 195 1450 1561 1435 1562 0.93

Sequence Information

Coding Sequence
atgcataggcctcctccagGGGAAGACAACACGTCTCCAATACGATGGTCGCCTCCAAGTTCTGCCGCCCTGGTAGCTGCTGCGCTAGCGCCACCTGCGCTAAGACCCTGGCTCCCGGACCCGCCCATCAAGAAGACCAACCATTTGGGTCTGGTGTGCGTAGTGTGTGGAGACACAAGCTCAGGCAAGCACTACGGCATTCTGGCTTGCAACGGATGCAGCGGTTTCTTCAAAAGATCTGTGAGGAGAAAACTTATATACAGATGCCAGGCCGGTACTGGAAGGTGCGTGGTGGACAAAGCACACCGGAATCAGTGCCAGGCTTGTCGGCTGAAGAAATGTCTGGCTATGGGCATGAACAAGGATGCTGTGCAGAACGAGCGTCAGCCCCGGAACACCGCCACCATAAGACCGGAAGCTCTGCGAGACATGGACCAGGAGAGGGCGCTACGAGAAGCTGCGGTAGCTGTTGGAGTATTTGGGCCCCCAGTGTCCCTCGCGATGGCGCTGTCCCCGGCACGGTACCCGCTGCTGTCGCCGCACtacgcgccgctgccgccgcagccgccgccgccgcagcagccaGACTCCTCGCACGACCACCACGACGGCAGCCACGCGCACTCCGACAGCGATGATGACAGTATTGATGTGACCAATGAAGAAGACTCCACATCGTATTCCCCTCCAGCCGTGTCCAGCTATTCCCAAAGTTGTATACCATATGGACCACTTGGCGTAGAAAGTGCGGCGGAAACTGCAGCCCGCTTGCTGTTCATGGCGGTGAAGTGGGCCAAAAACTTACCTTCCTTCGCCAGCCTTGCCTTTCGGGATCAGGTGATTCTCTTGGAAGAAGCGTGGTCGGAACTGTTTCTGCTGAACGCGATACAGTGGTGCGCGCCGCTGGACGCCGCGTGCGCAGCGCTCTTCGGCACCGAGCAGACCGATCAAGagaATGGCGCGTCGTCGGTGCTGCGCAGGCTCCGCTCCGTGGTGTCGCGCTACCGCAGCGTGCTGGTGGATCCCGCGGAGTTCGCCTGCATGAAGGCCATCGCGCTGTTCAAGTGCGGTAACTATCCACTATCCATCAACATTGTAGAGAATGGCACGTCTTCGGAGTTGCGCAGGCTCCGCTCCGTGGTGTCGCGCTACCGCAGCGTGCTGGTGGATCCCGCGGAGTTCGCCTGCATGAAGGCCATCGCGCTGTTCAAGTGCGGTAACTATCCACTATCCATCAACATTGTAGAGAATGGCACGTCTTCGGAGTTGCGCAGGCTCCGCTCCGTGGTGTCGCGCTACCGCAGCGTGCTGGTGGATCCCGCGGAGTTCGCCTGCATGAAGGCCATCGCGCTGTTCAAGTGCGGTAACTATCCACTATCCATCAACATTGTAGAGAATGGCACGTCTTCGGAGTTGCGCAGGCTCCGCTCCGTGGTGTCGCGCTACCGCAGCGTGCTGGTGGATCCCGCGGAGTTCGCCTGCATGAAGGCCATCGCGCTGTTCAAGTGCGGTAACTATCCACTATCCATCAACACTGTAGAGAATGGCACGTCTTCGGAGTTGCGCAGGCTCCGCTCCGTGGTGTCGCGCTACCGCAGCGTGCTGGTGGATCCCGCGGAGTTCGCCTGCATGAAGGCCATCGCGCTGTTCAAGTGCGGTAACTATCCACTATCCATCAACATTGTAGAGAATGGCACGTCTTCGGAGTTGCGCAGGCTCCGCTCCGTGGTGTCGCGCTACCGCAGCGTGCTGGTGGATCCCGCGGAGTTCGCCTGCATGAAGGCCATCGCGCTGTTCAAGTGCGGTAACTATCCACTATCCATCAACATTGTAGAGAATGGCACGTCTTCGGAGTTGCGCAGGCTCCGCTCCGTGGTGTCGCGCTACCGCAGCGTGCTGGTGGATCCCGCGGAGTTCGCCTGCATGAAGGCCATCGCGCTGTTCAAGTGCGGTAACTATCCACTATCCATCAACATTGTAGAGAATGGCACGTCTTCGGAGTTGCGCAGGCTCCGCTCCATGGTGTCGCGCTACCGCAGCGTGCTGGTGGATCCCGCGGAGTTCGCCTGCATGAAGGCCATCGCGCTGTTCAAGTGCGGTAACTATCCACTATCCATCAACATTGTAGAGAATGGCACGTCTTCGGAGTTGCGCAGGCTCCGCTCCGTGGTGTCGCGCTACCGCAGCGTGCTGGTGGATCCCGCGGAGTTCGCCTGCATGAAGGCCATCGCGCTGTTCAAGTGCGGTAACTATCCACTATCCATCAACATTGTAGAGAATGGCACGTCTTCGGAGTTGCGCAGGCTCCGCTCCGTGGTGTCGCGCTACCGCAGCGTGCTGGTGGATCCCGCGGAGTTCGCCTGCATGAAGGCCATCGCGCTGTTCAAGTGCGGTAACTATCCACTATCCATCAACATTGTAGAGAATGGCACGTCTTCGGAGTTGCGCAGGCTCCGCTCCGTGGTGTCGCGCTACCGCAGCGTGCTGGTGGATCCCGCGGAGTTTGCCTGCATGAAGGCCATCGCGCTGTTCAAGTGCGGTAACTATCCACTATCCATCAATATTGTAGAGAATGGCACGTCTTCGGAGTTGCGCAGGCTCCGCTCCGTGGTGTCGCGCTACCGCAGCGTGCTGGTGGATCCCGCGGAGTTCGCCTGCATGAAGGCCATCGCGCTGTTCAAGTGCGGTAACTATCCACTATCCATCAACATTGTAGAGAATGGCACGTCTTCGGAGTTACGCAGGCTCCGCTCCGTGGTGTCGCGCTACCGCAGCGTGCTGGTGGATCCCGCGGAGTTCGGCTGCATGAAGGCCATCGCGCTGTTCAAGTGCGGTAACTATCCACTATCCATCAACATTGTAGAGAATGGCACGTCTTCGGAGTTACGCAGGCTCCGCTCCGTGGTGTCGCGCTACCGCAGCGTGCTGGTGGATCCCGCGGAGTTCGGCTGCATGAAGGCCATCGCGCTGTTCAAGTGCGGTAACTATTCACTATCCATCAACATTGTAGAGAATGGCACGTCTTCGGAGCTGCGCAGGCTCCGCTCCGTGGTGTCGCGCTACCGCAGCGTGCTGGTGGATCCCGCGGAGTTCGCCTGCATGAAGGCCATTGCGCTGTTCAAGTGCGGTAACTATCCACTATCCATCAACATTGTAGAGAATGGCACGTCTTCGGAGTTACGCAGGCTCCGCTCCGTGGTGTCGCGCTACCGCAGCGTGCTGGTGGATCCCGCGGAGTTCGCCTGCATGAAGGCCATCGCGCTGTTCAAGTGCGGTAACTATCCACTATCCATCAACATTGTAGAGAATGGCACGTCTTCGGAGTTACGCAGGCTCCGCTCCGTGGTGTCTGGCTACCGCAGCGTGCTGGTGGATCCCGCGGAGTTCGCCTGCATGAAGGCCATCGCGCTGTTCAAGTGCGGTAACTATCCACTATCCATCAACACTGTAGAGAATGGCACGTCTTCGGAGTTGCGCAGGCTCCGCTCCGTGGTGTCACGCTACCGCAGCGTGCTGGTGGATCCCGCGGGATTCACTTGCATGAAGGCCGTCACGCTGTTCAAGTGCAGTAACTATCCAATATCCATCAACACTGTAGAGAAAGGCGCGTCGTCGGTGCTGCGCAGGCTCCGCTCCGTGGTGTCGCGCTACCGCAGCGTGCTGGTGGATCCCGCGGAGTTCGCCTGCATGAAGGCCATCGCGCTGTTCAAGTGCGGTAACTATCCACTATCCATCAACACTGTAGAGAATGGCACGTCTTCGGAGTTGCGCAGGCTCCGCTCCGTGGTGTCGCGCTACCGCAGCGTGCTGGTGGATCCCGCGGGATTCACTTGCATGAAGGCCGTCACGCTGTTCAAGTGCAGTAACTATCCAATATCCATCAACACTGTAGAGAAAGGCGCGTCGTCGGTGCTGCGCAGGCTCCGCTCCGTGGTGTCGCGCTACCGCAGCGTGCTGGTGGATCCCGCGGAGTTCGCCTGCATGAAGGCCATCGCGCTGTTCAAGTGCGGTAACTATCCACTATCCATCAACACTGTAGAGAATGGCACGTCTTCGGAGTTGCGCAGGCTCCGCTCCGTGGTGTCGCGCTACCGCAGCGTGCTGGTGGATCCCGCGGAGTTCGCCTGCATGAAGGCCATCGCGCTGTTCAAGTGCGGTAACTATCCACTATCCATCAACACTGTAGAGAATGGCACGTCTTCGGAGTTGCGCAGGCTCCGCTCCGTGGTGTCGCGCTACCGCAGCGTGCTGGTGGATCCCGCGGGATTCACTTGCATGAAGGCCGTCACGCTGTTCAAGTGTAGTAACTATCCAATATCCATCAACACTGTAGAGAAAGGCGCGTCGTCGGTGCTGCGCAGGCTCCGCTCCGTGGTGTCCCGCTACCGCAGCGTGCTGGTGGATCCCGCGGAGTTCGCCTGCATGAAGGCCATCGCGCTGTTCAAGTGCGAAACCCGCGGCCTCAAGGAGCCGCTGCAGATCGAGAACCTGCAGGACCAGGCGCAGGTGATGCTGATGTCGCACGCGCGCGCGGCGCAcggcgcggcgcccgcgcgctTCGGCcgcctgctgctgctgctgccgctgctgcGCCTCGTGCCGCCGCACCAGCTCGAGCGAGAGTTCTTCTCCAAGACCATCGGACACACGCCCATGGAGAAGGTCTTGGCTGACATGTACAAGAATTGA
Protein Sequence
MHRPPPGEDNTSPIRWSPPSSAALVAAALAPPALRPWLPDPPIKKTNHLGLVCVVCGDTSSGKHYGILACNGCSGFFKRSVRRKLIYRCQAGTGRCVVDKAHRNQCQACRLKKCLAMGMNKDAVQNERQPRNTATIRPEALRDMDQERALREAAVAVGVFGPPVSLAMALSPARYPLLSPHYAPLPPQPPPPQQPDSSHDHHDGSHAHSDSDDDSIDVTNEEDSTSYSPPAVSSYSQSCIPYGPLGVESAAETAARLLFMAVKWAKNLPSFASLAFRDQVILLEEAWSELFLLNAIQWCAPLDAACAALFGTEQTDQENGASSVLRRLRSVVSRYRSVLVDPAEFACMKAIALFKCGNYPLSINIVENGTSSELRRLRSVVSRYRSVLVDPAEFACMKAIALFKCGNYPLSINIVENGTSSELRRLRSVVSRYRSVLVDPAEFACMKAIALFKCGNYPLSINIVENGTSSELRRLRSVVSRYRSVLVDPAEFACMKAIALFKCGNYPLSINTVENGTSSELRRLRSVVSRYRSVLVDPAEFACMKAIALFKCGNYPLSINIVENGTSSELRRLRSVVSRYRSVLVDPAEFACMKAIALFKCGNYPLSINIVENGTSSELRRLRSVVSRYRSVLVDPAEFACMKAIALFKCGNYPLSINIVENGTSSELRRLRSMVSRYRSVLVDPAEFACMKAIALFKCGNYPLSINIVENGTSSELRRLRSVVSRYRSVLVDPAEFACMKAIALFKCGNYPLSINIVENGTSSELRRLRSVVSRYRSVLVDPAEFACMKAIALFKCGNYPLSINIVENGTSSELRRLRSVVSRYRSVLVDPAEFACMKAIALFKCGNYPLSINIVENGTSSELRRLRSVVSRYRSVLVDPAEFACMKAIALFKCGNYPLSINIVENGTSSELRRLRSVVSRYRSVLVDPAEFGCMKAIALFKCGNYPLSINIVENGTSSELRRLRSVVSRYRSVLVDPAEFGCMKAIALFKCGNYSLSINIVENGTSSELRRLRSVVSRYRSVLVDPAEFACMKAIALFKCGNYPLSINIVENGTSSELRRLRSVVSRYRSVLVDPAEFACMKAIALFKCGNYPLSINIVENGTSSELRRLRSVVSGYRSVLVDPAEFACMKAIALFKCGNYPLSINTVENGTSSELRRLRSVVSRYRSVLVDPAGFTCMKAVTLFKCSNYPISINTVEKGASSVLRRLRSVVSRYRSVLVDPAEFACMKAIALFKCGNYPLSINTVENGTSSELRRLRSVVSRYRSVLVDPAGFTCMKAVTLFKCSNYPISINTVEKGASSVLRRLRSVVSRYRSVLVDPAEFACMKAIALFKCGNYPLSINTVENGTSSELRRLRSVVSRYRSVLVDPAEFACMKAIALFKCGNYPLSINTVENGTSSELRRLRSVVSRYRSVLVDPAGFTCMKAVTLFKCSNYPISINTVEKGASSVLRRLRSVVSRYRSVLVDPAEFACMKAIALFKCETRGLKEPLQIENLQDQAQVMLMSHARAAHGAAPARFGRLLLLLPLLRLVPPHQLEREFFSKTIGHTPMEKVLADMYKN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00353121;
90% Identity
iTF_00353121;
80% Identity
iTF_00353121;