Basic Information

Insect: Cochliomyia hominivorax
Gene Symbol: Bcl11a
Assembly: GCA_004302925.1
Location: PYHX01000041.1:16852-20572[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.00096 0.05 14.0 0.9 3 23 204 224 202 224 0.97

2 6 5.4e-05 0.0028 18.0 2.9 1 23 240 263 240 263 0.97

3 6 0.00042 0.022 15.1 2.4 2 23 270 291 269 291 0.97

4 6 0.025 1.3 9.6 3.5 6 23 299 317 296 317 0.94

5 6 7.3e-07 3.8e-05 23.8 3.4 1 23 597 619 597 619 0.99

6 6 1.1e-05 0.00057 20.1 0.5 1 23 625 647 625 647 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.00096	0.05	14.0	0.9	3	23	204	224	202	224	0.97
2	6	5.4e-05	0.0028	18.0	2.9	1	23	240	263	240	263	0.97
3	6	0.00042	0.022	15.1	2.4	2	23	270	291	269	291	0.97
4	6	0.025	1.3	9.6	3.5	6	23	299	317	296	317	0.94
5	6	7.3e-07	3.8e-05	23.8	3.4	1	23	597	619	597	619	0.99
6	6	1.1e-05	0.00057	20.1	0.5	1	23	625	647	625	647	0.97

Sequence Information

Coding Sequence: atggatgaaaaatGCCATCTTtgtcaacaaataaataatttaacaataatttataatacagaactaaaatatttagcacaaattatattaaaacttaaaggTTACAagGACTctttgaatattgaaaaatatttcgcAGTTTGTGAAAAATGTCATCAAGGATTACAATTTTTTGCGGAGTTCTGGCAAAATATACCAGATATTGgagaacaagaagaagaagaacgaGAAAAACCAtctgaaatacaaataaattttccaaaagaagCTAAAGTAGCAAAAAGTCCCAAACAACAGGAAGTTAATAACGAGCCCATTAAAATACGCATTAAATTGCcacaaaaaaggaataaaaaccCTAAAACTAGTAGCGACAATTTggtaataaataatgaaatcataaatacCAAACGTTTAAGACGTCCACCCAAACGTTATgaggaatttaaaacaaatacctTTAATCAGCTTCCAACACAAACAAATTCTTCAAATTCATGCTTGGATAATTTTCCGGTAATATCATTTTTACGTTTTCCTAATGGTCTCGAAGTGGGAAAACTAATTGAGGTCGAAAGTAAGGGTGCCTGCTCTAGAGTAAGAATTATTTGCCAAAAATGCCTTCAAACATTTCGCTATGAAAAACAGTTTGAAATTCACATAAAAACTCATGATTTACtcacatcaaatcaaaatttacctttagaaaaaattttatattattgcaaATTATGTGATAAATCCTTCCGTGAACATTACGCTGTAAGAAGACATTATCGAATAGCTCATTCTGAGGAGAGACCTTTAAAATGTGAACATTGTGAAGCAAGTTTTAAGtacaaattcaATCTGGACTATCATATGGCTAAACATATTCCCAAAAAGCATTATTTCTGCACAATGGCTTTCGCGCACCGTACCAATTTAAAGACCCATCAAAGAGTAAAACATTTTAAGGACTCTGCAATTAGAAACAATtcaaaagaaaaggaaattaatgaaaatgatgCGTTAACtggtaaaataaaagaaaattatccaaAAGAACGGGAAAAAAGAACTTCTGAAACCATAAATCTAGACATTAACGAATCTATAGACGAGAAAACTTTgttggaaaaagaaaatatgaaattaaacattccaatggattttaaaaatgtctccaataatttaaatagtttaaacgATGCCAAACTGCCGGAAACTATAACTACCAATACAAGCAATACCGATCATAAAGTTTCGGAAACTGATCAAAATAATGCTGAAGATACTGAATTTATTTGTAATGCTTTGGAAAGGTTTAGTAATACACCTAATTTTGGCACATTTCATTTAGATACAAGTATTTTAAAGGTTTTGCCCTCATCAGAACTTTTGGGCTTAAAGAAATGGCCAAAATCCTATCAAAATATAACTTTTGCTAAATGCAATTCGGAGAATGTAAAAAATGaagttattaaacaaaatcagGAAGCTGGAAATACATCTGTTATGAAATACATACCATTAGAAAAGAATTCGAActtgaaacaaaatattaatatttcaagtaTTTCAAAATCATCTAAACCAAATAAAGATTCTTTCCAAGATGAAATAGACAAATCACAAACtaatgaaaacaaacaaataacaaattttgaagtTCCAAGTGGACAATCATTACTAAAACCTGAATTGAAATCCCATCAAATTTCTTCTTCAACTTTAACGAGATCtcctaaaaatgaaaataatttggCTCCTCAGCAAAATCTTATCAAACCTCCTGCCAATTATAAGTATCAATGTACGtattgttggaaatattttaaacaaaaatcaccATTAACAAAACATCTACGCACCCATACGGGAGAGAAACCCTACAAATGTAATTTATGTCCTAAAGCTTATGCTGATGCTTCCAActataaaaagcataaaattttacataaaaatgctGCCGAagctttaaatattaagaacaaCTCAAACTCCTATGCAATTCCAAATTCTCCTGCTTATTCAACTGTCTCCGATCCAGATCCAGATGGTTTAGAAGTTATGCAAACTATTAAAAAGTTTGAGGATGACAATGATGAgattgatgatgataatgactcTTTAAGTTCTGCAACAATGGAATCGTATATGTGGCAAGATGCTTTAGAAAATGCCTTAATGAATGACGATATacgtgaaaatattaaaagaaatttagcaGATTTAAATCATGCTATaatgcctaaaagtatgcaacaaTTGGATGGAAAGATAATGAACAATTTTTCAACTGAAGATCCGGATTAG
Protein Sequence: MDEKCHLCQQINNLTIIYNTELKYLAQIILKLKGYKDSLNIEKYFAVCEKCHQGLQFFAEFWQNIPDIGEQEEEEREKPSEIQINFPKEAKVAKSPKQQEVNNEPIKIRIKLPQKRNKNPKTSSDNLVINNEIINTKRLRRPPKRYEEFKTNTFNQLPTQTNSSNSCLDNFPVISFLRFPNGLEVGKLIEVESKGACSRVRIICQKCLQTFRYEKQFEIHIKTHDLLTSNQNLPLEKILYYCKLCDKSFREHYAVRRHYRIAHSEERPLKCEHCEASFKYKFNLDYHMAKHIPKKHYFCTMAFAHRTNLKTHQRVKHFKDSAIRNNSKEKEINENDALTGKIKENYPKEREKRTSETINLDINESIDEKTLLEKENMKLNIPMDFKNVSNNLNSLNDAKLPETITTNTSNTDHKVSETDQNNAEDTEFICNALERFSNTPNFGTFHLDTSILKVLPSSELLGLKKWPKSYQNITFAKCNSENVKNEVIKQNQEAGNTSVMKYIPLEKNSNLKQNINISSISKSSKPNKDSFQDEIDKSQTNENKQITNFEVPSGQSLLKPELKSHQISSSTLTRSPKNENNLAPQQNLIKPPANYKYQCTYCWKYFKQKSPLTKHLRTHTGEKPYKCNLCPKAYADASNYKKHKILHKNAAEALNIKNNSNSYAIPNSPAYSTVSDPDPDGLEVMQTIKKFEDDNDEIDDDNDSLSSATMESYMWQDALENALMNDDIRENIKRNLADLNHAIMPKSMQQLDGKIMNNFSTEDPD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -