Basic Information

Insect: Cochliomyia hominivorax
Gene Symbol: Bcl11a
Assembly: GCA_004302925.1
Location: PYHX01003044.1:422079-426195[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.00091 0.047 14.1 1.4 3 23 205 225 203 225 0.97

2 7 6.8e-05 0.0035 17.6 2.9 1 23 241 264 241 264 0.97

3 7 0.00053 0.027 14.8 2.4 2 23 271 292 270 292 0.97

4 7 5.5e-06 0.00029 21.1 1.4 1 23 298 320 298 320 0.99

5 7 0.00023 0.012 16.0 4.0 1 23 326 349 326 349 0.98

6 7 9.2e-07 4.7e-05 23.5 3.4 1 23 768 790 768 790 0.99

7 7 8.4e-06 0.00043 20.5 0.5 1 23 796 818 796 818 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.00091	0.047	14.1	1.4	3	23	205	225	203	225	0.97
2	7	6.8e-05	0.0035	17.6	2.9	1	23	241	264	241	264	0.97
3	7	0.00053	0.027	14.8	2.4	2	23	271	292	270	292	0.97
4	7	5.5e-06	0.00029	21.1	1.4	1	23	298	320	298	320	0.99
5	7	0.00023	0.012	16.0	4.0	1	23	326	349	326	349	0.98
6	7	9.2e-07	4.7e-05	23.5	3.4	1	23	768	790	768	790	0.99
7	7	8.4e-06	0.00043	20.5	0.5	1	23	796	818	796	818	0.97

Sequence Information

Coding Sequence: atggaagaaaaatgCCATCTTtgtcaacaaataaataatttaacaataattaatgatacagaactaaaatatttagcacaaattatattaaaacttaaaggTTACAagGACTctttgaatattgaaaaatattttgcaatttgtgaaaaatgtcaTCAAGGATTACAATTTTTTGCAGAGTTCTGGCAAAATATACCAGATATTGgagaacaagaagaagaagaagaacgaGAAAAACCAtctgaaatacaaataaattttgcaaaagaagCTAAAGTAGCAAAAAGTCCCAAACAACAGGAAGTTAATAACGAGCCCATTAAAATACGCATTAAATTGCCACAGAAAAGGAATAAAAACCCTAAAACTAGTAGCGACAATTTggtaataaataatgaaatcataaatacCAAACGTTTAAGACGTCCTCCCAAACGTTATgaggaatttaaaacaaatacctTTAATCAGCTTCCAACACAAACAAATTCTTCAAATTCATGCTTGGATAATTTTCCGGTAATATCATTTTTACGTTTTCCTAATGGTCTCGAAGTGGGAAAACTAATTGAGGTCGAAAGTAAGGGTGCCTGCTCTAGAGTAAGAATTATTTGCCAAAAATGCCTTCAAACATTTCGCTATGAAAAACAGTTTGAAAATCACATTAAAACTCATGATTTACtcacatcaaatcaaaatttacatttagaaaaaattttatattattgcaaATTATGTGATAAATCCTTCCGTGAACATTACGCTGTAAGAAGACATTATCGAATAGCTCATTCTGAGGAGAGACCTTTAAAATGTGAACATTGTGAAGCAAGTTTTAAGtacaaattcaATCTGGACTATCATATGGctaaacatatttccaaaaagcattatgtatgtgaattttgtaaaaagtcgTTTGTTTTACGTTATGAATTGAAAATTCATCTTAGGACTCACACAAAAGAAAAGCCCTATACATGTCAGTTCTGTACAATGGCTTTCGCGCACCGTACCAATTTAAAGACCCATcaaaaagttaaacattttaagtaCTCTACGATTAGTAACAATtcaaaagaaaaggaaattaatgaaaatgatgCGTTAACtggtaaaataaaagaaaattgtccaAAAGAACGGGAAAAAAGAACTTCTGAAACCATAAATCTAGACATTAACGAATCTATAGACGAGAAAACTTTGtgggaaaaagaaaatataaaattaaacgttccaatggattttaaaaatgtctccaacaatttaaatagtttaaacgAACCCAAACTGCCGGAAACTATAACTACCGATACAAGCAATACCGATCATAAAGTTTCGGAAACTGATCAAAATAATGCTGAAGATACTGAATTTATTAGTAATGCTTTGGAAAGGTTTAGTAATGCACCTAATTTTGGCACATTTCATTTAGATACAAGTATTTTAAAGGTTTTGCCCTCATCAGAACTTTTGGGCTTAAaaaaatggccaaaatcctaTCAAAATGTAACTTTTGCTAAATGCAATTCGGAGAATGTAAAAAATGaagttattaaacaaaatcagGAAGCTGGAAATACATCTGTTATGAAATACATACCATTAGAAAAGAATTCGAACtcgaaacaaaatattaatatttcaagtaTTTCAAAATCATCTAAACCAAATAAAGATTCTTTCCAAGATGAAATAGACAAATCACAAACtaatgaaaacaaacaaataacaaattttgaagtTCCAAGTGGTAGTACCCTAATAAAAGGTggcaaatttataaatatttcaaaactttccAGTTCAACTTCCTTAAAAAATCttgataatattaaaagaactgaaattattgataataaaaatgaaaaggacCATTTAAATTCTTCTAGAGACAAAAGTTGTGAAGTTTCAAAAGTCACAAAAAACTCTCAATCTTGGAAAGTAATTAAAGTCTCTTCAAGGCCCATTAAAAtcataacattaaataaaacaaaagtaaactTAAGCAACATTAAAACTACAACTCCACTTAATAAATCACATGGCGagaattctattttaaaatctcCTTTTAAGCATACAAAATCAACTGGACAATCATTACTAAAACCTGAATTGAAATCCCATCAAATTTCTTCTTCAACTTTAACGAGATCtcctaaaaatgaaaataatttgggTAATAAacctttaataacaaatatagaAATTCTACCGCCTCTGGCAGCTTTAGCACCAACAGCTTTAACTTCAGCTCCTCAGCAAAATCTTATCAAACCTCCTGCCAATTATAAATATCAATGTACGtattgttggaaatattttaaacaaaaatcaccATTAACAAAACATCTACGCACCCATACGGGAGAGAAACCCtataaatgtaatttatgtCCTAAAGCTTATGCTGATCCTTCCAActataaaaagcataaaattttacataaaaatgctGCCGAagctttaaatattaagaacaaCTCAAACTCCTATGCAATTCCAAATTCTCCTGCTTATTCAACTGTCTCCGATCCAGATCCAGATGGTTTAGAAGTTATGCAAACTATTAAAAAGTTTGAGGATGACAATGATGAgattgatgatgataatgactcTTTAAGTTCTGCAACAATGGAATCGTATATGTGGCAAGATGCTTTAGAAAATGCCTTAATGAATGACGATATacgtgaaaatattaaaagaaatttagcaGATTTAAATCATGCTATaatgcctaaaagtatgcaacaaTTGGATGGAAAGATAATGAACAATTTTTCAACTGAAGATCCGGATTAG
Protein Sequence: MEEKCHLCQQINNLTIINDTELKYLAQIILKLKGYKDSLNIEKYFAICEKCHQGLQFFAEFWQNIPDIGEQEEEEEREKPSEIQINFAKEAKVAKSPKQQEVNNEPIKIRIKLPQKRNKNPKTSSDNLVINNEIINTKRLRRPPKRYEEFKTNTFNQLPTQTNSSNSCLDNFPVISFLRFPNGLEVGKLIEVESKGACSRVRIICQKCLQTFRYEKQFENHIKTHDLLTSNQNLHLEKILYYCKLCDKSFREHYAVRRHYRIAHSEERPLKCEHCEASFKYKFNLDYHMAKHISKKHYVCEFCKKSFVLRYELKIHLRTHTKEKPYTCQFCTMAFAHRTNLKTHQKVKHFKYSTISNNSKEKEINENDALTGKIKENCPKEREKRTSETINLDINESIDEKTLWEKENIKLNVPMDFKNVSNNLNSLNEPKLPETITTDTSNTDHKVSETDQNNAEDTEFISNALERFSNAPNFGTFHLDTSILKVLPSSELLGLKKWPKSYQNVTFAKCNSENVKNEVIKQNQEAGNTSVMKYIPLEKNSNSKQNINISSISKSSKPNKDSFQDEIDKSQTNENKQITNFEVPSGSTLIKGGKFINISKLSSSTSLKNLDNIKRTEIIDNKNEKDHLNSSRDKSCEVSKVTKNSQSWKVIKVSSRPIKIITLNKTKVNLSNIKTTTPLNKSHGENSILKSPFKHTKSTGQSLLKPELKSHQISSSTLTRSPKNENNLGNKPLITNIEILPPLAALAPTALTSAPQQNLIKPPANYKYQCTYCWKYFKQKSPLTKHLRTHTGEKPYKCNLCPKAYADPSNYKKHKILHKNAAEALNIKNNSNSYAIPNSPAYSTVSDPDPDGLEVMQTIKKFEDDNDEIDDDNDSLSSATMESYMWQDALENALMNDDIRENIKRNLADLNHAIMPKSMQQLDGKIMNNFSTEDPD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -