Chom003084.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Cochliomyia hominivorax
Gene Symbol
ZNF275
Assembly
GCA_004302925.1
Location
PYHX01003180.1:931195-934393[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.04 2.1 8.9 0.1 1 23 195 217 195 217 0.96
2 15 1.3e-05 0.00066 19.9 0.4 2 23 224 245 223 245 0.97
3 15 8.4e-07 4.4e-05 23.6 0.2 1 23 293 315 293 315 0.98
4 15 6.1e-06 0.00032 20.9 0.7 1 23 424 446 424 446 0.96
5 15 0.039 2 9.0 1.6 1 23 452 474 452 474 0.95
6 15 4e-06 0.00021 21.5 0.3 1 23 491 513 491 513 0.98
7 15 0.08 4.1 8.0 0.4 2 23 524 546 523 546 0.93
8 15 0.00066 0.034 14.5 4.9 1 23 552 574 552 574 0.98
9 15 0.00018 0.0092 16.3 0.4 2 23 581 602 580 602 0.97
10 15 2.2e-08 1.1e-06 28.6 0.7 1 23 608 630 608 630 0.96
11 15 0.0078 0.41 11.1 2.1 1 23 636 658 636 658 0.98
12 15 8.3e-05 0.0043 17.4 1.3 1 23 664 686 664 686 0.93
13 15 1.2e-05 0.0006 20.0 3.2 1 23 692 714 692 714 0.99
14 15 2.1e-06 0.00011 22.4 0.7 1 23 720 742 720 742 0.99
15 15 7.3e-05 0.0038 17.5 1.4 1 23 748 770 748 770 0.97

Sequence Information

Coding Sequence
atgtcATCTAACGATTTATCTTCCAAATGCCGCACTTGCTTAAGTGCCTCCAAAGTTTATCATCAACTTTTCGATTATGTggaggaaaattataaaattctcgaAATGTTGGATGGTATTGTGCCCCAAATAGATATTAAGACCTCTTCCCAATTTTCCACTTTGGTATGTGATTCGTGCGTGGAAAAACTGTTGACCGGTTATAAGTTTCAACAATTGTGTATTGAAACCAATAATCGTTTACATGATTTGCTGGGTCTGGCGGTGTTTGAGACACAaccaaaattggaaaaaattttagatcCTTTAACGGGTGAGgcaagttttaaaatgaaagagGAGATACCAGAAGAATTTGTAAGTGAAATACCTACAGGTGAGCTCTCGGAGGCAATAGCATCGGATAATGAAGATTGGGCGGCTCCACCTGATGATGACGGAGGTGGTCTCAACGATAGCGGAAGTGATACAGATTCAAGCAATGAAAAGCTTTCTGTCTTAAAAGAAAGATCCACTAAGAAATCTCCTTTAAAAGTGGAAACTATAGAAAAatccTCAAAAATAAATCGTCGTAAGGGTAATTTCCCTTGCGCGGAATGTGCAAAAGTATTTGGTAGTATTAATCGTCTAAAACAGCATACAGCTGTACATGAAAAAAAGCGGGCTCTTTCATGTGAAATTTGCAATATTAGTTTTAGCACTGAGAAATCCTTAAAAGCTCATACATTAACACACACAAATGGTGAAATATCAACAAAAGACTCAAAATCTGAAGATACACAAAATCATGAAACAGATAACAGTAAACATAAATCCCTAGATAATAAAGAGGAAGCTGATAGTGAAGAAGGTAAAGATTCTAAACAAATGCAAATATTTCAATGTCCTGATTGTCCTAAAGTGTTTGAGAAGAAAGCTTCTTTGTCGGCCCATTACAAAGTGCATAAGAAAAAggaattaataaataacaaaagtaaaaaattcgaACAAGCTAAtgaggaaaataataaagaagacATTAATGAAAATGATGTTATCGTTAAAGAGGAAATTGAAATTACACCACAAATCTTTGAAGAACCTTTGGATGATATAGATGAGGTTGAAGGTGACTGGTTTAATAATGATTATGATGAATCAGATGGTGATCCGGATAAGGAACTTTTTGTCAAACCCCGaccaaaagaaacaaataaaaatattgatttcattGATACAGGAGTAGGTGAAATAGAAAAACCCAACAGCAGCAATAAAAGAAGTGGACAATTTCCTTGTAAAATGTGTGGGAAAGTTTTTGATCGTCCTTATCGTTTAAAACGCCACAGTTCTGTGCATTCGCCCAGTCGACCTCACGAAtgtgaaatttgtaaatatcGTTTTGCCACCCTCAATATTCTTAAGTCTCATATATTTCAGCATGAGAACGAAACGGGTTTATTTCTTAGCTTGCAGTCACGGCCCGAAGGTTTTAAATGTCCCGATTGTCCTAGACGTTTTGAAAAACAGGCGTCACTCTCTGCCCATCGTCAAATACACACACGCAATGCTTCAGAATCCAATGGCTTACCTTGCATGGTTTGTCAACGTAATTTCATGTCGGTGAGATCTTTAACAGAACATATCACCAATAAACATCCCGAAGTGGAGAAACACAAATGCGATCAGTGTGATAAAACTTTTGTTCTACATGCTCATTTAGTGGAACATTTAAATCGTCATAAGGGCAATCGCAATCTTGTGTGTTTGATATGTGAGAAGGAATTTGGCTATACGAACACCTTAAAAGAACACATGCGTACACATAGTGGTGAAAGTCCCTATTTATGCCCTCAATGTGGTAAAACATTCCGTAGTGCTAGTAATTTAAGACAACATATGGAAAGACATACTGGTTTAAAGAAATATCAATGTTCTGAATGTCCAAGTCGTTTTAATTGTCGTTCAGATTTAATAAAACATGCCTCAACGCACTCGAATGCTAAACCGCATGTCTGTGATATATGTGGTTCTCGATTTACAAGGGCCTATTCTTTACAAAAACACAAAGTGTTGCATACAGGAGAAAGACCATTCAAATGTGATCAGTGCAATATGACTTTTGCTATAGTTTATCATCTAAGACGCCATATGCGCACTCACACTGGTGAGAAACCTTACAAATGTAAATACTGTGAGCGAGCTTATGCTGAAAGTGGGGATTTGACAAAACATTTGAGAACCCATGTGGGGGAAAATACCTATATGTGTGATCAATGTCCTATGGCCTTTAAATATCAAGCAGAATTAAGACATCACCAATCGCAACATTATAAAATGGCACAAAAACTTTTGCAACAAGCGCAAAAAATGTCCGAAGATGctcaacaacaagaacaactatCCCAAACACAGCTTGAACAACAGCAAACACAATTAACAACAAGTTTAACAGAACAATCGCCACAATTACATAATGAAgaacaacaattattaaaaaatgaacaaatacaaaatttacccTTGTCAATAACAAGTTATCAGCAAATTCCTTTAATCCACCATAGACAACAATTAACAGAACAAACGTTACAACATCATGAAAAAATACATGATAGTCTAGTAATGAGTACACAAACGCAACTTCAATCACAGCAAGACAATTAG
Protein Sequence
MSSNDLSSKCRTCLSASKVYHQLFDYVEENYKILEMLDGIVPQIDIKTSSQFSTLVCDSCVEKLLTGYKFQQLCIETNNRLHDLLGLAVFETQPKLEKILDPLTGEASFKMKEEIPEEFVSEIPTGELSEAIASDNEDWAAPPDDDGGGLNDSGSDTDSSNEKLSVLKERSTKKSPLKVETIEKSSKINRRKGNFPCAECAKVFGSINRLKQHTAVHEKKRALSCEICNISFSTEKSLKAHTLTHTNGEISTKDSKSEDTQNHETDNSKHKSLDNKEEADSEEGKDSKQMQIFQCPDCPKVFEKKASLSAHYKVHKKKELINNKSKKFEQANEENNKEDINENDVIVKEEIEITPQIFEEPLDDIDEVEGDWFNNDYDESDGDPDKELFVKPRPKETNKNIDFIDTGVGEIEKPNSSNKRSGQFPCKMCGKVFDRPYRLKRHSSVHSPSRPHECEICKYRFATLNILKSHIFQHENETGLFLSLQSRPEGFKCPDCPRRFEKQASLSAHRQIHTRNASESNGLPCMVCQRNFMSVRSLTEHITNKHPEVEKHKCDQCDKTFVLHAHLVEHLNRHKGNRNLVCLICEKEFGYTNTLKEHMRTHSGESPYLCPQCGKTFRSASNLRQHMERHTGLKKYQCSECPSRFNCRSDLIKHASTHSNAKPHVCDICGSRFTRAYSLQKHKVLHTGERPFKCDQCNMTFAIVYHLRRHMRTHTGEKPYKCKYCERAYAESGDLTKHLRTHVGENTYMCDQCPMAFKYQAELRHHQSQHYKMAQKLLQQAQKMSEDAQQQEQLSQTQLEQQQTQLTTSLTEQSPQLHNEEQQLLKNEQIQNLPLSITSYQQIPLIHHRQQLTEQTLQHHEKIHDSLVMSTQTQLQSQQDN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01259358;
90% Identity
-
80% Identity
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