Basic Information

Gene Symbol
ZIPIC
Assembly
GCA_014851415.1
Location
Chr23:8256240-8262794[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.0079 0.51 10.7 1.8 2 23 57 78 56 78 0.96
2 12 0.015 1 9.8 0.7 3 23 86 107 84 107 0.93
3 12 0.0026 0.17 12.2 0.5 2 23 115 137 114 137 0.94
4 12 0.00016 0.01 16.1 5.8 1 23 143 165 143 165 0.98
5 12 9.8e-07 6.4e-05 23.0 2.8 1 23 171 193 171 193 0.96
6 12 0.0006 0.039 14.2 1.9 1 21 199 219 199 220 0.93
7 12 0.00015 0.01 16.1 1.2 3 23 239 260 238 260 0.95
8 12 5.8e-06 0.00038 20.6 2.4 1 23 581 603 581 603 0.98
9 12 0.00057 0.037 14.3 0.3 3 21 612 630 611 633 0.90
10 12 0.0098 0.64 10.4 0.4 1 23 641 664 641 664 0.94
11 12 5.4e-05 0.0036 17.5 0.7 3 23 672 694 671 694 0.93
12 12 0.00023 0.015 15.6 1.6 1 21 700 720 700 721 0.95

Sequence Information

Coding Sequence
ATGGAGTCCAATATATCATTTTTCAGTCTTCCATTCGTGGATTCTGAGTCTTCCGACTTAGTCTTTAATAAAATCAAGCCTCAGGAAGCCTACGAAGAAGTGTTAGCACAGTTTTTGTCTGGCGACGAACCTCTAGAGGAGCCAGACTTGAATGGGCCTACGACTCTTCATTGTGAGATTTGTCGCAAGCAGTTTGATAATGCCAAGAAGTACTATGGCCATTTACGTGTTCATTCTAAGGAATGTCTCTGGATATGTGACAAATGTCCAGACCAGAAGTTCTCCACAAAGCAACAGTTGATGAAGCACAGCCTGAGCCACCAGCCGCTGGAGCGTGTGTGGCGCTGTCCACAGTGCAACTTGTCATTTGAGTCGCTCTGGCGCTTGCAGCAACATCTCTTCTCTAAACACTTAGAATATAGACCTCACAAATGTGACCAATGTGAGAAAGCATTTCACAAAAAATCTGATCTAACTAAGCATAAAAATGTGCATGATGTCGTAAAGAAACATGCATGTTCAGAATGTGAGATGAAATTCAAAGATAAATCAAATTTGAATCGCCACATGTTGAAACATACTGGCAACAAACCATTCTGCTGTTCAGGCTGCGGTAATAAATTTAAACAGCTAGGATCATTAAAGAGACATGCGAAAAATTGCATATACTATGTAACAAGTCACAATGAGGATAGTAAAATTAGGAAGAATCATTGTGGAATCTGTGGAATGTCTTTTAAATACAAGAGCACTTTATTGGAACATTATGCCAGACAACATTCAAACTCTCCTGACCAAAGTGCACCAGTAGAAGAAAAACCAACTCCAACCCCAGAAAATCAAATAGTTGACAATAGGACTGAAGACAACATAGTAGATGATATTCTCTCTGCCGAGGACGATTACATGACTATGCCTACACAAAACGAAATTCTGAACACTTATAATACTCAAACTGAATCTGCCATCAACAATGAAAACCTGATGCAGATTGAGTTCCTTAAAGATATGAATCAGTTGCACAGTCTAGATGATGAGCTTTTCTACAATGATATAGACTTTGAAAGCTTTCAAAACAACCACATTTTCAATATGAACACAAATGATATGGATTACAACACTCAGGATAGGAACACAGAAATATTGTTTGACTTTGCAGACCCTGGCCGAAGTATGGACCAGGACATAATGAATGCACTGTATCATGTCAAACCTGATCATTTACCTGACGAGCTATTGAATGTGCCTGAAGTAGAAAATTTTAATGACACAAATAATAGGCCTAATGAGTTGCTGAATCCAACAGTTTCGGTCAATGAGTGTGCTACTATATTTGAAAGTGATGTTGATCTAGAAGCTAGTGCAAATTTAGCAGCAAATCTAAACCAGTTGATTGGCGAGAACAATGTTCAGTACATTTCGACAGAGGATGATGATACTTTTATTATAAGTTTAAAGAGCGAAATAGATGCAGCACAGTTGACCGACATGCTGAATATGGCTAATGAACTAGCTGATAATAATAAAGAATCAGAGGAGCTTGTATCTGCAAGTACTTCAGATGCAAATGTGGAGACTTCTGAGAATCTAGAAAATAATATTGTAGAACCAATTGTTTTGAAGATAGAAGAAAAAACTATTCAACCTACTATAACTATCAACGCGGGCGTGATAAGTAGACATGGAGAGGAGACTGAAATCAAAACGGCAAAGAAGACTAAGGCGAAAAAGAAAGTTCTTTACGTTTGTCGGAAATGTAATAAGGTGTTTAATAAGAAGAATAACTTTACATCGCATATCGCCACGCACGAGCCGTCCCTGCGTCAGCACGGCTGCTCGGTGTGCGGCGAGCGCTTCGGGTACAAGTCGTCGCTGAACAAGCACTTCGCGGCGCAGCACTCGGCGCGCGTGCTCCCCGAGCACGCCTGCACGCTCTGCGACAACACCTACCGCGCTGCTTGGATGCTCCAACAGCACATGGATCGCGACCACAATCAACTCAAGCGCGTGGCGTGCGACAGGAAAGGCTGTGGGAAGAAGTTCTTCAAGAAAAGCGATCTCGTTGTTCATTTAAGGTCCCACACGGGGGAGCGGCCGTTCGCGTGCGACATCTGCAAGAAGCGGTACCAGCACGTGTCGCATCTGAAGAGGCACGTCAGGGCCGTCGACTGCACTAAACGGACCTAA
Protein Sequence
MESNISFFSLPFVDSESSDLVFNKIKPQEAYEEVLAQFLSGDEPLEEPDLNGPTTLHCEICRKQFDNAKKYYGHLRVHSKECLWICDKCPDQKFSTKQQLMKHSLSHQPLERVWRCPQCNLSFESLWRLQQHLFSKHLEYRPHKCDQCEKAFHKKSDLTKHKNVHDVVKKHACSECEMKFKDKSNLNRHMLKHTGNKPFCCSGCGNKFKQLGSLKRHAKNCIYYVTSHNEDSKIRKNHCGICGMSFKYKSTLLEHYARQHSNSPDQSAPVEEKPTPTPENQIVDNRTEDNIVDDILSAEDDYMTMPTQNEILNTYNTQTESAINNENLMQIEFLKDMNQLHSLDDELFYNDIDFESFQNNHIFNMNTNDMDYNTQDRNTEILFDFADPGRSMDQDIMNALYHVKPDHLPDELLNVPEVENFNDTNNRPNELLNPTVSVNECATIFESDVDLEASANLAANLNQLIGENNVQYISTEDDDTFIISLKSEIDAAQLTDMLNMANELADNNKESEELVSASTSDANVETSENLENNIVEPIVLKIEEKTIQPTITINAGVISRHGEETEIKTAKKTKAKKKVLYVCRKCNKVFNKKNNFTSHIATHEPSLRQHGCSVCGERFGYKSSLNKHFAAQHSARVLPEHACTLCDNTYRAAWMLQQHMDRDHNQLKRVACDRKGCGKKFFKKSDLVVHLRSHTGERPFACDICKKRYQHVSHLKRHVRAVDCTKRT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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