Basic Information

Insect: Clunio marinus
Gene Symbol: zfh2
Assembly: GCA_900005825.1
Location: CVRI01000074.1:289400-316733[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.32 24 5.9 0.4 2 23 170 192 169 192 0.95

2 11 0.00015 0.011 16.3 1.4 2 23 512 534 511 534 0.96

3 11 3.8e-05 0.0028 18.2 0.7 1 23 566 590 566 590 0.92

4 11 0.04 3 8.7 0.2 2 20 1242 1260 1241 1264 0.92

5 11 0.73 54 4.8 2.9 1 23 1337 1362 1337 1362 0.89

6 11 0.00022 0.017 15.8 0.6 1 23 1375 1397 1375 1397 0.97

7 11 9.5e-05 0.0071 17.0 1.3 2 23 1404 1426 1403 1426 0.94

8 11 0.016 1.2 10.0 0.5 1 22 1503 1524 1503 1527 0.89

9 11 0.0058 0.43 11.4 0.1 1 23 1600 1624 1600 1624 0.93

10 11 4.5 3.3e+02 2.3 4.4 1 19 1738 1756 1738 1761 0.93

11 11 0.00026 0.019 15.6 2.8 1 23 2324 2346 2324 2346 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.32	24	5.9	0.4	2	23	170	192	169	192	0.95
2	11	0.00015	0.011	16.3	1.4	2	23	512	534	511	534	0.96
3	11	3.8e-05	0.0028	18.2	0.7	1	23	566	590	566	590	0.92
4	11	0.04	3	8.7	0.2	2	20	1242	1260	1241	1264	0.92
5	11	0.73	54	4.8	2.9	1	23	1337	1362	1337	1362	0.89
6	11	0.00022	0.017	15.8	0.6	1	23	1375	1397	1375	1397	0.97
7	11	9.5e-05	0.0071	17.0	1.3	2	23	1404	1426	1403	1426	0.94
8	11	0.016	1.2	10.0	0.5	1	22	1503	1524	1503	1527	0.89
9	11	0.0058	0.43	11.4	0.1	1	23	1600	1624	1600	1624	0.93
10	11	4.5	3.3e+02	2.3	4.4	1	19	1738	1756	1738	1761	0.93
11	11	0.00026	0.019	15.6	2.8	1	23	2324	2346	2324	2346	0.98

Sequence Information

Coding Sequence: ATGCCACCGCCAACATCCCCCACAACGGCACCATCACCAAGAAAACGGAGACGAAAGCGTGAAGATCCACAATCCTGTCTCACAAACTCGGAGCAGGAATACGATTCTGACGATGCCTCTCCATCATCATACGCTGAAGTTGAGCGATTTCAAGGCAAAGTTGTTTATAATTTAGATGGTAAGGCATACATTATAGATGCCGACAACGAGCTATCACTTCAACTGTCTGATAGTAGTATTAAAGATGTATCACAATCAAACAATCcaaaaattcaatcatttcGTGTCATTTCTTCGCGCGATGCCACTATGAACTCATCTTCTTCCTCCCAGTCATCGGTTGGTGCTTCGGCTTCATTTACTGCCGAAGATGCATCACCAACTACGACACCATCGcttgaacaacaacaacaacagcagcagcattCAGACGAGAAAAATTTTGACAAAAATGACAACAGCAGtcagcatcaacaacaacttcaacGTCAACAGAAGCCGATTCTCATGTGTTTCATTTGCAAGTTGAGTTTCGGAAATATTAAGTTGTTTTCATCACATGCTAACACTGAACATAGATTGAATCTCAGTGAGTCAGAAAAGACGTTGCTGTGTCGCGAGTATTCGTCGGCAATCATTCAGAAAAACAGCGACGAAAACTCACAAATATCATTTCTCGAGCCTCTTGATGCAACGATGGCTAAAACAACAGCGATGGCTACATCGCCGTTTGATATCagtaaaagtaatttaaatgataGTGTTAATGATAacaatgataataataataatagtaatAATAATCATGATGACGGTACTGAGAATGATGACGAGCCCGATCTAACGGCTGTTAAAACAGATATCAATAAGGAAGCTCAAGACGAGCATCAGCCGAGATTAACGCCAAAATCTTTGTCGTCACTTACCGGTCGCACATCACCGCCCCCGCCACCCGCACTCAATGTTCTTCAGCGTTTGACGGGTGGTGACTTTAAGTTCCTAAACACGTCAGCTGATTTGTCACAGCTCACAAGTCTTCTTGAGCAGCACAAGTCACTGAACGAGTTCCTcgcacaacaacaacaacatcaacagcaacaacaacatcagcaacGTCTAGCGTGTCCCGAACATGCAGACACACCTAATCTCAACGACATCGACTgcaaaaattgtgaatttttaaacattaatcaattaaattcacaACTCACCCTTAAATCACCGATCAAAGGTAGTTTCGGCCAACATCAGACGGAATCAAATGCTTCATCAACCTCATCGAAGACATCTTCACCGATAACTTCTTCCGTCACACCAAACTCTGCTCTTCAACTTCACCAAAaccttcaacaacaacaacaacagcaacaaaatataaatacatCTCCAAGTTTCACTATCGGGGCTTGTCCCGATCATATGAATGGGCGACCCATTGGAGTCGATTGTGCAAGGTGTGAAATTCTTCTAAACTCTGCACGTCTCAACAGTGGTGTTCAAATATCAACCAGAAACTCCTGCAAGACTCTTAAATGTCCCCAATGCAATTGGCATTACAAGTATCAAGAGACATTAGAAATACATATGCGCGAAAAACATCCAGATGGTGAGAGTGCATGTGGCTACTGTCTGGCTGGTGCTGCCCACCCACGCCTAGCACGTGGAGAGTCTTACACATGTGGCTATAAACCATATCGCTGTGAAATTTGCAACTATTCAACGACCACAAAAGGCAATCTCTCTATTCACATGCAAAGTGATAAGCATTTGAATAATGTACAGGAACTGAGCAGTACACAGAACCTTAGCGTCGCACCACCGCCAGAAATTCGCACATCTCAACCACCTAGTCAAACAACTCCAGTATCTGCCCCATCAACACCACTGCCACAGCAATGTAAACCAAAACCGAAGCCGAGTTTCCGCTGTGAGCCATGTTCATATGAAACTCCAAATGCGCGTAATTATCGTATCCACGAAACAAGCGAAAAGCACACGCACAATCTTGCTGTTGTTCAGTGCAATATCAAACGACTGCAATCACATATGGATTCATTCCTTCAGCAGACTCATTCTGGAGTCAAAGGTGGAATGGCTCAAATACCGTCAATGGAACAACAAGCACAACAAAATCCGGGCCATTTACCTGGCGCTGCTTTGGCTGATCTTGCTTACAATCAAGCACTACTTATTCAGCTTCTTCATCAGAATTCTGTTGGATTAGGTAGCACAACTGGTCCCGCATTCATGTCACTAttacaacaacagcagcaacaacaacaagcgCAGACTAATCAACAAAGTCAACTTCATTATCAACAAATTAATGGAACGAACAACCAAGATATTGATCAAGGTTTGAATCCTGACACTCTTGAGCCACCCTTCGAACAAGATTTCAACCCAGTGTATAATTTCTCATGTCTCATTTGCTCAAATTTCAATACAAACGACCTCGAAGAGTTGAACAACCACATCAATGAGGATCGATCGAGACTGAGCTTCCCTCAGGAATTTATTGTGGTTCTGAATAACAACAACTACACATGTCGATTATGTTGTTACAAAACTCATCTGAAGGCAAATTGTCAACTTCATTGTAAAACCGACAAACATTTACAAAGAGTCAACTTCGCTAATCACATTAAGCAAGgCGGGCTAAGAAAcgaatataaatttgattacGTCATTAACTCAACAACGACAAATAACAATTACAATATTACGCAATTGAAGTGTAATTGCTGCGATTATTACACAAATTCTATTCAGAAGCTTAATTGTCATATCCAAAATGTTCGCCatgaaagcatgaaaataaagtttaatcatCTCGTACAATTGTTTAAAGAAGTAAAGTTTGAATCGATTGATGGTCAGGATATCAATAATAAAGCATTGCAATGTCAGCTGTGCAATTTCAAGACAAACAGCATACTTGACATGGTAAAGCACAACAAAAGCTTACGTCATATTCAAATCGAACAAATTTACTGTCTTCAGAGGCGATGTGAGAGTTTGGAGTCAATGGATATTGGAGATGTTTATCAGCTTGTTGACGATCTCGATTCATCTTGTTCTGATTATCAGAAAGAAGACGAAAAGCCAAATCTTTCGCCATCATCACGAAACGCACCACAGAATGCTAAATCGACTCAAAAAATACCGGAAAATGATGGATTGTCAATAAGGTCATCGACACCATTAGATATTCTTAAGATGGTTCCATTTGAACAGCTTCAGCAACTAGCTGCAACACTCCCACCATCACAAACGATTCTTAAGTGCAACCAGTGTGATCATTTGtgtgaaaataaagttgaaatggAACAGCATTTCGATCAAAATCATCCCAACAATCCGGATTGCAATTCGATTGTGCTTCCTTCGATGGCAGCTTTAATGGCTGCTGCACAAATGAACTTTGAACCAAAGACAGATCAGATCAAAAGTGATGACAAATCAGATGATTTGACTGACAAAATGCTCGATGATTCTGATAAATCAAAGCAAAATTGTGACACCGATGTAATGACAATTGAACCGGATATTGATGGTGtcattattaataattcatcTCGATCTTCTTCCGCTGTCTCGATGCTGGAAGGCGATGAGAAAATCTCCACAGGAGCAATGCGAACAACACCACAAAACCAGCAAATGCAGAAGTCTTCACCTTTCTCAACTTCGTCAGTTACTGCTGATGAATATAGCATCATGTGTCCACTTTGTCAAGAATCatttgttgaaagaaaagctttggAACAACATGTCATGTGCATCCATAGTGTCAATGCTGATGGTCTCAATCGACTGCTTCAGCTTGTTGACACGAGTCATTGGCTCAACAACAAGAAAAGTCCAGAAAGAAGCGCTTCAACTGGTGCCGTCTCGAATGGGGATTTTGAATGTTTAGTTTGTTCCGACACACTTAAGAACATGAACGATCTACTGATGCACGCAACTGACCACCAACATTTTTCCATTACTGGTCTAAATCAATTCAGTTGCTTGTTGAAATCGTGTCATCAAAGATTCTCAAATGAACAACAAGTTCAACAACATTTCCGTTCTGCACATCTCAATATCGTGATTAGCGAACGACATGTTTATAAATATCGATGTCCAATGTGTCCACTTGCATTTAAAACTGAAGAGAAGCTTAACAATCACTTCATGTATCATACAATGAGAGACGCAACAAAATGCAATATTTGTAATCGTAATTTTCGCTCAACAACATCTCTTCAACGTCATATCGAACAAGTTCATTCAACACCTGCTCAAGACTTAAATAAGTCAACCGATCTAACTGATGATGAAAGAATGCAAACGCCACATGATGAAGCTTTATCAAATGATGACGATCAAGAAGAGTACGATGGTCAAAATAGTGAAAATATTAACGAAGAGTCGAATGCGAAGAGATTTAAAGCAATGAAGCGGAATGAGAAGATAACAAATTACTCATTGGAGAAATATCACGATCCGAATCGACCGTATAAATGTGAAGATTGCTTTGAAAGCTTCACACAAGCCAACATTTTAACAGTCCACAAGAATAGCGTTTCGCATTTACATCGTGTaaagcaaaagcaaaaagaGACACACAGTGGAAGTTCAACTCCCGCTTTAGCCACGTCGCCAAATCAACTTGGCGACTTTGATCGACGATCTGTTGATTTCGATAAGAAATCGATTGATTACGAGATGGAAATTTCAAACACAACTGGAGATTCAAATAAGCGGAAATTATCATCAGACAATGATTATGACAGTCCGAAGAAACGTTTCAAATGTGACATTTGTAAAGTTGCTTATGCTCAAGGATCTACTCTTGACATTCATATGAGAAGTGTTGGTCATCAGGCAAAGGCCAATCGCATCATGCAGCAACAGTTGCAACAAGGTTCGTCGACATCAACGACAGCAAATTCTCAGGATCTCTTGCAACAAGCACAAGTGACGGTGAACAACGGAAACAGTTCTCCAAACCTTGCCAATAATCAAATGTACAAAACGTTGCTAGAAAACTTTGGTTTTGATATTGTTAAGCAATTCAACGATATTAATAAGTTGGGACAACAGAATGATTTGTTGAACTTGGGTGCAGCTGTAGGGAAAGTTCCGCAAATCACACCGAATTTGTTATCAAAGAAGAATGgaaataatgatgaaaagaaggaTGAAAAGAaggatgaaaagtttttctgtcGTCACTGCAAACAAGGCTTCAATAATGTGTTTGCATTGAAGACTCATTGTGAAGAAGCTCATGGTGAGAAAATTCCACTTGAGATGCTGGAGAAAGAACAAGAAAGTGAAGTTCTCGATTTCTCACAAACAAAGTCAAGTGCTGACAGTGAACATCCTGAAAACATGCCAATGGTCGAtccaatgaaacttttcaatcctGAATTACTTCAGCAAAAAATGAACGAACAAAAGTTTGACCCTGCAATGCTTGCACAAAGATTGATGGAGCAACAATTTCTCGCACAATTTCCTCAAATTTCTCAGAGTTTGCAGAATCTAACGACGGGAAATTTACCGATGAATACTCTTGAGATGCTTAATTTGATGCAATTTCATCACTTTATGTCgttgaatttcatgaatttagcGCCTCCATTAATTTTTGGGGGTGGTCAACAAGGAAGCAATCTTTTGTCTGCCGGACCTACTGCCGTGAATCCAATCTTGCCAGCTCCTAAACCAGTGTCAGAATCAGCATCTCCTGCTGCATCATCGGTTGCCCCAGCTTTATCTCTtcttcaacagcaacaacaacagcagcaacagcaacaacaggCGACTGCTAATCAACTTCAAGCACAAGCTTGTGGAAGTCAGAAAAGGGCAAGAACACGCATCACTGATGAACAGTTGAAGATTTTGAGATCACATTTTGATATCAACAACTCGCCGAGTGAAGAAAGCATTCAGGAGATGTCGAAGAAAGCTAATTTGCCACAAaagGTCGTTAAACATTGGTTCCGTAACACACTGTTCAAGGAACGCCAACGCAATAAAGATTCACCTTACAACTTTGCAAATCCACCGTCGACAACTTTGAATCTCGAAGAATATGAGCGAACTGGAACCGCAAAAGTGACTGCACTGTCTGAAAGCAAAGCTCAGAATACAACAACAAGTCAATCTAATTTACTGATGAACAATTTACAACATCAGCAAAAACTCGaacaacaaaaacttcaagaaCAGCAACAGCAGTTTTTTCAACAACAAGCCCAACAAGCGTTTAATTTAAGTCAACAATCTCAGCAGAATTTTCCCGATTTACGTCCAATCTCTCAACCATCGAGTACCACAAGTAATGAACGTGACGAGTCATTTATTAAGTCAGAGCCGATGGATGAAATGATGAGCGAAATGGACGGTAAAAATGAAGGAATGGAATATGAGATGGAACGCTATCGTCAACAACAGGCGCAGAATTTCTTTCTGAACAGCTATGAAACGAAATCTGAAAGTGGTAGCTCTGACATTTTATCTCGACCTCAAACACCAAACAGTCTCTATAACAACATCAACGACGTCATTAATCAGCAAATTGAAAGTATTCCAATCAATAACATCACTGGTGGTTCGAACATGAATCAGATGGGACCACCAAAGAAGTTTCaactgaataaaatatttgacaaaaGTTATGAGTCTAATTCGAGCTCATCAAATTCGTCAACATCGAGTGGAAAGCGAGCAAATCGTACACGTTTCACGGATTACCAGATAAAAGTTCTACAAGAGTTTTTCGAGAATAATTCTTATCCAAAAGACAGTGACTTGGAGTATTTGAGtaaacttttgcttttgtcGCCAAGAGTCATTGTCGTCTGGTTCcagAATGCTCGTCAAAAGCAACGAAAGATCTACGAGAATCAGCCAAACAGCacaaaCACGCCATATGATGCCACCGAAGAGAAGAAATCAGCGATAAATTACACGTGTAAGAAATGCAATTTAATATTCCAACGATATTATGAACTCATTCGACATCAAAAGAACCATTgtttcaaagaagaaaataacaaaaagtcAGCGAAAGCTCAAATCGCTGCCGCCCAAATAGCTCAGAGCTTGAGCAGCGAAGACTCTAACTCAAGCTTAGAAATAAATCACGCCAGTAATCTATTAGTACCAGCCGTTGGATTTCCACCAACAATCAGCTCCCAGCTTGCTCTGTCACAACAACCAACAAGCGTTCGAAGTGGGTCCACATCCGGAATCACACCAGAACTTTAA
Protein Sequence: MPPPTSPTTAPSPRKRRRKREDPQSCLTNSEQEYDSDDASPSSYAEVERFQGKVVYNLDGKAYIIDADNELSLQLSDSSIKDVSQSNNPKIQSFRVISSRDATMNSSSSSQSSVGASASFTAEDASPTTTPSLEQQQQQQQHSDEKNFDKNDNSSQHQQQLQRQQKPILMCFICKLSFGNIKLFSSHANTEHRLNLSESEKTLLCREYSSAIIQKNSDENSQISFLEPLDATMAKTTAMATSPFDISKSNLNDSVNDNNDNNNNSNNNHDDGTENDDEPDLTAVKTDINKEAQDEHQPRLTPKSLSSLTGRTSPPPPPALNVLQRLTGGDFKFLNTSADLSQLTSLLEQHKSLNEFLAQQQQHQQQQQHQQRLACPEHADTPNLNDIDCKNCEFLNINQLNSQLTLKSPIKGSFGQHQTESNASSTSSKTSSPITSSVTPNSALQLHQNLQQQQQQQQNINTSPSFTIGACPDHMNGRPIGVDCARCEILLNSARLNSGVQISTRNSCKTLKCPQCNWHYKYQETLEIHMREKHPDGESACGYCLAGAAHPRLARGESYTCGYKPYRCEICNYSTTTKGNLSIHMQSDKHLNNVQELSSTQNLSVAPPPEIRTSQPPSQTTPVSAPSTPLPQQCKPKPKPSFRCEPCSYETPNARNYRIHETSEKHTHNLAVVQCNIKRLQSHMDSFLQQTHSGVKGGMAQIPSMEQQAQQNPGHLPGAALADLAYNQALLIQLLHQNSVGLGSTTGPAFMSLLQQQQQQQQAQTNQQSQLHYQQINGTNNQDIDQGLNPDTLEPPFEQDFNPVYNFSCLICSNFNTNDLEELNNHINEDRSRLSFPQEFIVVLNNNNYTCRLCCYKTHLKANCQLHCKTDKHLQRVNFANHIKQGGLRNEYKFDYVINSTTTNNNYNITQLKCNCCDYYTNSIQKLNCHIQNVRHESMKIKFNHLVQLFKEVKFESIDGQDINNKALQCQLCNFKTNSILDMVKHNKSLRHIQIEQIYCLQRRCESLESMDIGDVYQLVDDLDSSCSDYQKEDEKPNLSPSSRNAPQNAKSTQKIPENDGLSIRSSTPLDILKMVPFEQLQQLAATLPPSQTILKCNQCDHLCENKVEMEQHFDQNHPNNPDCNSIVLPSMAALMAAAQMNFEPKTDQIKSDDKSDDLTDKMLDDSDKSKQNCDTDVMTIEPDIDGVIINNSSRSSSAVSMLEGDEKISTGAMRTTPQNQQMQKSSPFSTSSVTADEYSIMCPLCQESFVERKALEQHVMCIHSVNADGLNRLLQLVDTSHWLNNKKSPERSASTGAVSNGDFECLVCSDTLKNMNDLLMHATDHQHFSITGLNQFSCLLKSCHQRFSNEQQVQQHFRSAHLNIVISERHVYKYRCPMCPLAFKTEEKLNNHFMYHTMRDATKCNICNRNFRSTTSLQRHIEQVHSTPAQDLNKSTDLTDDERMQTPHDEALSNDDDQEEYDGQNSENINEESNAKRFKAMKRNEKITNYSLEKYHDPNRPYKCEDCFESFTQANILTVHKNSVSHLHRVKQKQKETHSGSSTPALATSPNQLGDFDRRSVDFDKKSIDYEMEISNTTGDSNKRKLSSDNDYDSPKKRFKCDICKVAYAQGSTLDIHMRSVGHQAKANRIMQQQLQQGSSTSTTANSQDLLQQAQVTVNNGNSSPNLANNQMYKTLLENFGFDIVKQFNDINKLGQQNDLLNLGAAVGKVPQITPNLLSKKNGNNDEKKDEKKDEKFFCRHCKQGFNNVFALKTHCEEAHGEKIPLEMLEKEQESEVLDFSQTKSSADSEHPENMPMVDPMKLFNPELLQQKMNEQKFDPAMLAQRLMEQQFLAQFPQISQSLQNLTTGNLPMNTLEMLNLMQFHHFMSLNFMNLAPPLIFGGGQQGSNLLSAGPTAVNPILPAPKPVSESASPAASSVAPALSLLQQQQQQQQQQQQATANQLQAQACGSQKRARTRITDEQLKILRSHFDINNSPSEESIQEMSKKANLPQKVVKHWFRNTLFKERQRNKDSPYNFANPPSTTLNLEEYERTGTAKVTALSESKAQNTTTSQSNLLMNNLQHQQKLEQQKLQEQQQQFFQQQAQQAFNLSQQSQQNFPDLRPISQPSSTTSNERDESFIKSEPMDEMMSEMDGKNEGMEYEMERYRQQQAQNFFLNSYETKSESGSSDILSRPQTPNSLYNNINDVINQQIESIPINNITGGSNMNQMGPPKKFQLNKIFDKSYESNSSSSNSSTSSGKRANRTRFTDYQIKVLQEFFENNSYPKDSDLEYLSKLLLLSPRVIVVWFQNARQKQRKIYENQPNSTNTPYDATEEKKSAINYTCKKCNLIFQRYYELIRHQKNHCFKEENNKKSAKAQIAAAQIAQSLSSEDSNSSLEINHASNLLVPAVGFPPTISSQLALSQQPTSVRSGSTSGITPEL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00198911;
90% Identity: iTF_00346554;
80% Identity: iTF_00346554;