Basic Information

Gene Symbol
-
Assembly
GCA_900005825.1
Location
CVRI01000010.1:1384189-1387498[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 8.6e-05 0.0064 17.1 0.9 2 23 200 222 200 222 0.96
2 17 5e-05 0.0037 17.9 1.3 1 23 228 250 228 250 0.97
3 17 0.8 60 4.6 2.1 2 23 337 359 336 359 0.93
4 17 0.6 45 5.0 5.9 2 23 364 386 362 386 0.95
5 17 0.019 1.4 9.7 3.1 2 23 397 419 396 419 0.95
6 17 0.00059 0.044 14.5 1.6 1 21 425 445 425 448 0.90
7 17 0.0034 0.25 12.1 4.6 1 23 455 478 455 478 0.97
8 17 0.29 22 6.0 0.2 1 11 500 510 500 516 0.84
9 17 0.0021 0.16 12.7 1.5 2 23 535 556 535 556 0.98
10 17 6.7e-05 0.005 17.5 0.7 1 23 562 585 562 585 0.95
11 17 5.5e-05 0.0041 17.7 1.2 1 23 592 615 592 615 0.97
12 17 0.05 3.7 8.4 0.6 3 23 632 653 630 653 0.95
13 17 1.1 83 4.2 0.1 3 23 661 682 660 682 0.91
14 17 0.016 1.2 10.0 1.5 2 22 689 709 689 711 0.88
15 17 0.75 56 4.7 0.3 2 23 718 738 717 738 0.81
16 17 0.00033 0.025 15.3 2.2 1 23 743 766 743 766 0.94
17 17 8.1 6e+02 1.5 0.6 2 11 773 782 772 790 0.88

Sequence Information

Coding Sequence
atgacTGATTCAATAATTTGTCGTGTTTGCTTGGAAAATTGTGAGAAAACATCTCCAATATTTGATGAAAGTAAGAATGGACTGTCACTCGCTATGATGCTGATGGAAATTGGAGGGGTCGAGGTATCCATCCACGACAGCCTTTCAAAAAATATATGTGAAGGATGttcaaaagaaatgatgataGGACATGGACTAAGAATGCGATTTTTAAACTCAAATCAACATTTAAAGAGAGGGACGTCAAAGTTAACAAAAGATTTGCAAAGAAATGTGATTCCAGTCGTGAAATTATCAAGGATTGATCAAATCAAACTAATGATCAAAGAAGAGGTTACAGATTATAATTTGATAACATTTGTAGAACCCGAAAAAGGACTATTCATCGATGAAAATGATTACGTTAAAACTGAATTGGAGGAATCAAAAGAAGTGAACATTTtagataaaaacatttctgaaaATACTTCATCTAATTTATTAAAGGTAGTTATAAAAAGGAACAACAAATTTGTGTGTATGATTTGTGACTCTTGTCACAATTCTTGGAATCTTTGGCATAAACACTACTCAAAATCGCATAGCGAAATGCCAAACGTCTGCAAAGTATGTCAAGCTTCTTATAAAGATAAGTCTGAACTTAATCAGCATTATAAAAGTAGACACATGATTGGAGATACATTTATTTGCTCTATTTGTAATTTGAGGTTTCAAAGAAAATCGGAATTGTTTGAACATCAAGAGAAGCATGTCGATGACAATAATTCACTTGGAAATTCTAATAATGAAACAGGATTTGAATGTGTCAAACATGAAACAGATGTGAcagagaataatttaattaaaaattctccTAAATATGACgatattgaattgaaagagaattttGATGATTCTCGATCAAATATTTCTGATCACGAAGATTCAAATTGGATCTCAGATACAAGCAACGATATTAAGactgaagagaagaaaaatgtattGAAGAAACGTGACGATGGCCCTTTGATATGTTACatttgctttaaatatttcaattcatattttacaaaaaaGTCTCATTTAGAAAAATCTCATCAGGAGTGTACAAAATGTCAAATCTGTCctcaaatcaaattcaaagaTGTTTGTCATTATGAAAATCATATGAGGATTCACGCAGAGGGAGATTCAAAAAATGCAACAAAATCATGtgatttatgtaaatattcttCTAAAGAGAAATATTGTCTTATGAAACACATGAAAGCTGTTCATTTGAAGATTAAATCTTATAAATGTGAACAATGCGATGCATCATTTCGTTATGAATCAGATTATAAACAACACAAGTTTGGACTTCACAAAGCTCTTCCAGCAAGATTCACTTGCGATAAATGCGACCAAggtttcatatttaaatccAAATATAGCAGACATTTAGAGAAATGTCATAAAAACCCTTCCGTTGTTAATAAACTTAACTTCCCTGAACCAAAAAAGACTGACGAAGGAGGTTTCATTTGTTCAGTTTGTGGAAAAGGATTTCACAATGACACTGCTCAACGAAATAGAAGAAAGTGGTACTATCACTATCGAAATGCAcattatgaaaactttaatcgaTGCAAGATTTGCATGAAGAAATTTAGTGAAAGGGGAAAACTTTATGAACATATGAAAGTTCATGGCATTGtgaattttcatgtttgtaAAGTTTGTGGAATAAAATTCGTGACAGAGAAAAATCTTACATTGCATGTCTCAAAGGTTCATGATGGTCctaggaaaagttttaactgCAATGAATGTAGTGAAACATtcgataaaagaaatgaacttATGAAGCATGTGAGAAAAGAACACAAAGAAGCCAAAGATATTGTGGTAGATGAAAGAATGGCCAAAGATATTTGCTACATTTGTAATCAACCATTCAAGAGTCACATTTCGAAAATTAAACATGTTGAAACTGTCCATTCTGACTTTGTTCAAAGAGATTGCAACATTTGTGAAAAGAAGAGCATAATTTCGCCGAAAGCTTACGAGATTCACATGATGGAACACGTTAAAGGAAAGAATGAAGTTTGTCAACATTGTGGACAAAGTTTTGCACTTTTTCGTCAACTTCAGTCACACAGTGCACAGAAACATGCGGAAAGTAAAATGATTCAATGTGAGATTTGTGGAGAAAACGTTCACAAATACAAATTACCAGTTCACTTAATTAAACATAATGCTTCAAAGTTTCATTGTGAGTTATGTGACAAATCATTTGCATCAAAAATGCTCTTATGGAATCATAAATTTCGTGAGCATGGCGCAGATCCGAAATTAAATTGTCGCCATTGTGGAGAAGGTTTCGTTTTAACACGTGCTTGCAAACTACACGAAGAGAAATGCAAATCGGGAATAGTTCCAAAAAGAGGAAGACCAAAGGATTCAAAAGTTCACGtttaa
Protein Sequence
MTDSIICRVCLENCEKTSPIFDESKNGLSLAMMLMEIGGVEVSIHDSLSKNICEGCSKEMMIGHGLRMRFLNSNQHLKRGTSKLTKDLQRNVIPVVKLSRIDQIKLMIKEEVTDYNLITFVEPEKGLFIDENDYVKTELEESKEVNILDKNISENTSSNLLKVVIKRNNKFVCMICDSCHNSWNLWHKHYSKSHSEMPNVCKVCQASYKDKSELNQHYKSRHMIGDTFICSICNLRFQRKSELFEHQEKHVDDNNSLGNSNNETGFECVKHETDVTENNLIKNSPKYDDIELKENFDDSRSNISDHEDSNWISDTSNDIKTEEKKNVLKKRDDGPLICYICFKYFNSYFTKKSHLEKSHQECTKCQICPQIKFKDVCHYENHMRIHAEGDSKNATKSCDLCKYSSKEKYCLMKHMKAVHLKIKSYKCEQCDASFRYESDYKQHKFGLHKALPARFTCDKCDQGFIFKSKYSRHLEKCHKNPSVVNKLNFPEPKKTDEGGFICSVCGKGFHNDTAQRNRRKWYYHYRNAHYENFNRCKICMKKFSERGKLYEHMKVHGIVNFHVCKVCGIKFVTEKNLTLHVSKVHDGPRKSFNCNECSETFDKRNELMKHVRKEHKEAKDIVVDERMAKDICYICNQPFKSHISKIKHVETVHSDFVQRDCNICEKKSIISPKAYEIHMMEHVKGKNEVCQHCGQSFALFRQLQSHSAQKHAESKMIQCEICGENVHKYKLPVHLIKHNASKFHCELCDKSFASKMLLWNHKFREHGADPKLNCRHCGEGFVLTRACKLHEEKCKSGIVPKRGRPKDSKVHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-