Basic Information

Gene Symbol
zfy1
Assembly
GCA_905475355.1
Location
FR997803.1:17115584-17124785[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 1.6 1.6e+02 4.0 0.3 2 23 6 27 5 27 0.96
2 13 0.085 8.6 8.0 0.5 3 23 1027 1048 1025 1048 0.91
3 13 7.7e-06 0.00078 20.7 2.5 2 23 1151 1172 1150 1172 0.97
4 13 0.00018 0.018 16.4 2.5 1 23 1178 1200 1178 1200 0.98
5 13 0.083 8.5 8.0 3.2 2 23 1207 1228 1206 1229 0.94
6 13 0.57 58 5.4 1.9 5 23 1242 1260 1240 1260 0.97
7 13 0.02 2.1 10.0 1.1 3 23 1267 1288 1266 1288 0.96
8 13 0.0053 0.54 11.8 0.3 2 23 1305 1325 1304 1325 0.97
9 13 0.014 1.4 10.5 2.4 1 20 1331 1350 1331 1353 0.88
10 13 0.0055 0.56 11.8 2.0 1 23 1361 1383 1361 1383 0.98
11 13 0.0039 0.39 12.2 7.6 1 23 1389 1411 1389 1411 0.98
12 13 9.2e-06 0.00093 20.5 1.6 1 23 1417 1441 1417 1441 0.98
13 13 0.0025 0.25 12.8 5.2 1 23 1447 1469 1447 1470 0.95

Sequence Information

Coding Sequence
ATGGATCAACTCGTCCAGTGCCCCGTTTGCACACTGTTCCTCCATAATGGGATGAGTTTGGAGTCACACTTGGATACTCATCCCAAGGATCAAGTTATAAAGGCCCTTTGCAATTTAACATCTAAGGGCTCCAGTTGTGGAAGCAGGACTTCGACACCTTTAAATTCGGAAAGATCCTATCGGAGCAGGTCTCGAACTCCTGCCACTGAAGACAGCAGCCGATGGACCAGTTCTCATCGCAGTACTGATCATGAACGGTATTGGCGTAGAACACCTAGTAGGACTCCAAAGACAAATCCTACATCAAGTCTGTCAAGAAATAGCACTCCAGATATAAGGTTAGGTGAAATAAACTTTGAAACAGCCTCTACAACTAATAGTACTACACAACATAGTAGTCCGTTCATAACCAAAGTGGATAAAACCCAGCAAACATATCAAGCTTCCACTTTGTCAGAATATGATCAACACTATGTTTATTTTCCGGACTCGCAGGAGGATAGGGAAATCAAATACTCTAGAAGTGCGGAATATGCTGCTCTGGATAACACCAACAATCTGTTTACTTATAACATGCCAACAATGGGAGCAGGCATTAAATTGTTACCAGCTGTGCCAAGAAGAAGTAATGATATTGTTAAAATTGTACCTAAATCTAATAATATACTGCTCAAAACAAATGTAGGTGGAGTACAATACATAGGTGCAGGTGTTAAACCTATGCATGTAGTAGTGCCCACTGCCCCTACATTTGTCCAAAAGACTCAAAATAATATGATAGTAACTGGGAAATTGCCACCAAATGTACAAATGCAAATGGAAACAAAGGCTCCTTTGCATGCTACAAATCAGTTGCATCAAATGCCTCCAAATACTTTCGCTCCAAGCACTACCGTAGTTACCACAAATTCACAAATAATATACCAAGAGATGGTCCATAATATAGATGGCAAGCCATTCATAACAAGTATGCCCACTGTGCTTGGTGGTCATGACAATGTTGCCGATGTAGCTCAAGCATCTTCCATGTACCAAAATGTAATGGTAGTTGATCCATTTGGCAATGCATCTTGTATGTACCCAACACCTCAACAAATAGTTCCCAAAGTTTGTCCTACTTCAGTTTACAATGATGCAAGTCCATTACTGACTGGTATGCAAATTGATAGGCCTATCCAGGATGTGAGCGATGCCAAGTCTCTTATCATTGATGAAGGACCAATTCTACCTCCACCACCTGATATAGATCCAAATATTAATTGTGAAGTTATAGCCTCCAGCATGCCTCAGCCTGGTATTAGTGCTGCTACAGAAAAAGTAGACAAAGTAAAAAAGGATAATGTGGAAACCAAAAGTGAAACCCAAGGATCAACAAATAAAGGCTTAAAAATCCTTAGTAACATCAAAGTTGAAGTTCCTGTACAGCATCACAAAAATATGGTCAACACAATTATGGATCTTACTGGCTCAAGTGAAAATGATTATTCAATTTGTTCAGCTTCGCCTGAGAAGATTTTACCTGATCTACAGGATAATAATATGGCATCACACTTTAACAAAATATCAAATTTAAGTGCTACCGATCATAGTGACCATATTTCTGAACCTGAACGTATACTTCCTGATTTTGAGGACAATATACAAATTTTGTCAGATGAGAACACACAGCCATCTATGTCCAGTGCTGATAGTATTGTTTCAAATACATTTTCTGTGATAAAGAATGTTGGAAATCCTCCTTCCTATAAGGATTTTAATAAAACTGTAGCAGATACCAAGATAGAGACTGAGTTTTCAGATAGCTGTCCTGTACCAGATTTAATATGCAATGAGAAGCCTTCAATATCTCCTTGTAGTGAGCTATCAGAGATGGGAGATAATTCAACTGACCATACCTCAATTTCTCCCAATGCTGGGAGTAGTCAAACTAGCCATAAAGTTATAGATATCTCAGAGAAGAAACTTCAAAATCCACCAAAGTCTAGACAGAATGCACTGAGATTGAATAACATATATGTGAAGAAAAACAAGAAGGTATTGCAAATTAAGAACTCAAAGTCGTCTCCTGCAAAAGGTTCTAGCCACAAAGAAATAGAACCCGCACCATCATCATCAACTTGTAAATCTCCAGAAAATTTTTTTATAAGCAAAATGCATCAAAACAGGATTAACAATCCAACTAAAGTGAACAACCGAGTGTTGCTAACAATTTCTGTTGAAGAGGTTAAAGAGGGTGATCATAATGTTTTCGATGCTGATACAGAGGAACAGTCTATGGATATAGAGCCAGTTGCATCATCTACCTTGCACAATTCTAATGAACTTTCATCTGGAGAAACTGTATGTGTAAAAGAGGAAGTGAACAGTAGTAATGAAGGTGGTTTTAGTAATGAGACGGGCGCGTCGGGCCGCGGTGTCACCCCGATGGAAACTCTGCGCCCGATCAACGTTATCACATACGGAAATATGTCGTCGGCCGACTTCAATGATGAGTCGAATGATAGGGAACTCTTAGACCTTGAGGCTACAACGAAAAACAGGCAGTTTGTTAGTATGATGAATGAAAATTATTTCGGCGATAACATATACGCCGATTATTTTACGCCCGACCGAGTGGAGTCTTTCGATTCGGCGCGAGAATCGAGTATTTGGGGCGAGTCGTCGCAGAAGGAAAACGAGTTTGTTTTGCCGAATTTTATACATGAAAGTTACAAGATAGCTGAGAGTAACGGCATTGACTATTCTGAGCTGGGGTGTAGAGAGAAGAAGGTTGAAGCCATTGAAGTGTGCGAGCCAGACAGCAAGGTGGACTTGTTGAGCGAGAGGAGCGAAAGTGAGGTACCTCTGAACATCTGCGCGGACGAGCGTATGCCGTCTCGCGGAGAGCTTAGCGGCCAGGAGAGCAATGGCGATATGGAATCACCATGGAGCACTATGTACGCAGAGGGCGCTCCGTCAGAGCCTTATGACCTGATTGCCCGCGAGAGCTGGGTTTCGGATGGTTCGGAAATGGACGCCGCTGAGAAACGAGACACACTGGAAGAAGAGCTGCAGTTCGCCAAGAGCCGGCTGCTGGCGTGCGCGCAGTGCGGCGCCAAGTGCGCGTCGGCCAAGGAGCTGCGCGCGCACCGGGCGCACGCGCACGCGCACGCGCCGCCCGCCTGCGCCGCGCCCAAGACCACCTACAGCCGCCTCATCACCGCCAGGACTATCAAGAAGGAGAAGCAGGAGAAGATCACGCTGGCCAACAACCTCCTAACTCTGGACTCAAAAGAATCCATTACATCCACCATCTTGCAAGTCTATGAAAATATGGAGTCCAAGCCGAAACTGGAAGCACTCATTAAGCAAGAGCCAAAGCGGAAAAGGAGAGACTATGTCTGTCCCACGTGTAAGGTGGACCAGCTCTCGGATGCTGCTTTCCACGAACACCTGAAGATCCACCCTTTGGAGTGCCTGACTTGTGGGAAGTGCTTCTTCAGGAGATCGAACTTGGCACTGCATATCAAGACGCATTTAGGCATAAAGAACTACAAGTGTGAGGTGTGCGAGAAGCGGTTCATCACGCGGCAGAAGCTGATGGAGCACCACAACGTGCACACGGGCCGGGCGCCCATCAAGTGCACCGTCTGCTCAGACACCTTCCGCCGGTTCTCCAACATGGTGCAGCACAGGGACCGCCACCACAAGCATAAGCGAGGCAAGATCCGCGACTACGTGTGCCACTGCGGCGCCGTGTTCCATTCGCGGGCGAAGCTCCTGTGGCACAAGGAGACGCACGACGAGAAGCCCAAGGCCTGCCTCTACTGCAGCGACAAGTTCGTGCACGCGGCTTCGCTCACCAGGCACGTGAGGCGATCCCACAACGAGTTCCTGCTCACCGACAAGCTCAAAGGCAAGAGCGACAACGTGTCCTGTCCAGTTTGTAAACAGGTATACCTCAGATCGAACCTCCGCTCCCACCTTCTGACGCACAGCGGGCAACGGCCGTACCACTGCATCATATGCAACAAATACTTCACCACCAAATGGAACCTCAAGATCCACCGGTGGACCCACATGAGCCGTTCATCGAAACCCTTCAAATGCAACCTATGCAAGAGCGCCTTCATCCGACACACCGAGTACATATCCCACATGAACGCCCACAAGTCGGTCAAACCCTACACTTGTAATTACTGCGGCTGTCAATTCATTAGGAAATACAACTGCCAACGGCATCTGAGGGAGCACGAGACGGCCAAAAAGTACGTATGCAAGGTCCCCGAGTGTGGTAAGTCATTCCACCGTCGCTATTACCTGTCGGAGCACATGAAGGTCCACAGTGGCGCGAGGCCGTTCTCTTGTAATATATGCGGGAAAACGTCTAACAACAAGTCCAACCATAATAAACACGTCAAGATACATCACGCTCGCGAGCCGGTCGCTACTGAAGCGTAA
Protein Sequence
MDQLVQCPVCTLFLHNGMSLESHLDTHPKDQVIKALCNLTSKGSSCGSRTSTPLNSERSYRSRSRTPATEDSSRWTSSHRSTDHERYWRRTPSRTPKTNPTSSLSRNSTPDIRLGEINFETASTTNSTTQHSSPFITKVDKTQQTYQASTLSEYDQHYVYFPDSQEDREIKYSRSAEYAALDNTNNLFTYNMPTMGAGIKLLPAVPRRSNDIVKIVPKSNNILLKTNVGGVQYIGAGVKPMHVVVPTAPTFVQKTQNNMIVTGKLPPNVQMQMETKAPLHATNQLHQMPPNTFAPSTTVVTTNSQIIYQEMVHNIDGKPFITSMPTVLGGHDNVADVAQASSMYQNVMVVDPFGNASCMYPTPQQIVPKVCPTSVYNDASPLLTGMQIDRPIQDVSDAKSLIIDEGPILPPPPDIDPNINCEVIASSMPQPGISAATEKVDKVKKDNVETKSETQGSTNKGLKILSNIKVEVPVQHHKNMVNTIMDLTGSSENDYSICSASPEKILPDLQDNNMASHFNKISNLSATDHSDHISEPERILPDFEDNIQILSDENTQPSMSSADSIVSNTFSVIKNVGNPPSYKDFNKTVADTKIETEFSDSCPVPDLICNEKPSISPCSELSEMGDNSTDHTSISPNAGSSQTSHKVIDISEKKLQNPPKSRQNALRLNNIYVKKNKKVLQIKNSKSSPAKGSSHKEIEPAPSSSTCKSPENFFISKMHQNRINNPTKVNNRVLLTISVEEVKEGDHNVFDADTEEQSMDIEPVASSTLHNSNELSSGETVCVKEEVNSSNEGGFSNETGASGRGVTPMETLRPINVITYGNMSSADFNDESNDRELLDLEATTKNRQFVSMMNENYFGDNIYADYFTPDRVESFDSARESSIWGESSQKENEFVLPNFIHESYKIAESNGIDYSELGCREKKVEAIEVCEPDSKVDLLSERSESEVPLNICADERMPSRGELSGQESNGDMESPWSTMYAEGAPSEPYDLIARESWVSDGSEMDAAEKRDTLEEELQFAKSRLLACAQCGAKCASAKELRAHRAHAHAHAPPACAAPKTTYSRLITARTIKKEKQEKITLANNLLTLDSKESITSTILQVYENMESKPKLEALIKQEPKRKRRDYVCPTCKVDQLSDAAFHEHLKIHPLECLTCGKCFFRRSNLALHIKTHLGIKNYKCEVCEKRFITRQKLMEHHNVHTGRAPIKCTVCSDTFRRFSNMVQHRDRHHKHKRGKIRDYVCHCGAVFHSRAKLLWHKETHDEKPKACLYCSDKFVHAASLTRHVRRSHNEFLLTDKLKGKSDNVSCPVCKQVYLRSNLRSHLLTHSGQRPYHCIICNKYFTTKWNLKIHRWTHMSRSSKPFKCNLCKSAFIRHTEYISHMNAHKSVKPYTCNYCGCQFIRKYNCQRHLREHETAKKYVCKVPECGKSFHRRYYLSEHMKVHSGARPFSCNICGKTSNNKSNHNKHVKIHHAREPVATEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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