Basic Information

Insect: Cloeon dipterum
Gene Symbol: br
Assembly: GCA_949628265.1
Location: OX451260.1:14324334-14331221[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.29 21 5.9 3.2 1 23 322 344 322 344 0.94

2 11 0.00016 0.011 16.2 1.2 2 23 349 371 348 371 0.95

3 11 0.011 0.76 10.4 3.1 1 23 507 529 507 529 0.97

4 11 2.4e-06 0.00017 21.9 0.5 2 23 534 555 533 555 0.96

5 11 0.14 10 6.8 1.4 2 23 560 582 559 582 0.93

6 11 0.0014 0.1 13.2 2.6 1 23 630 652 630 652 0.98

7 11 2.5 1.8e+02 3.0 0.1 5 16 660 671 657 673 0.84

8 11 1.6e-07 1.1e-05 25.6 1.2 2 23 683 704 682 704 0.96

9 11 0.0046 0.33 11.6 5.0 1 23 735 757 735 757 0.97

10 11 0.00054 0.039 14.5 0.7 2 23 762 783 761 783 0.96

11 11 9.6e-05 0.0069 16.8 0.3 2 23 788 810 787 810 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.29	21	5.9	3.2	1	23	322	344	322	344	0.94
2	11	0.00016	0.011	16.2	1.2	2	23	349	371	348	371	0.95
3	11	0.011	0.76	10.4	3.1	1	23	507	529	507	529	0.97
4	11	2.4e-06	0.00017	21.9	0.5	2	23	534	555	533	555	0.96
5	11	0.14	10	6.8	1.4	2	23	560	582	559	582	0.93
6	11	0.0014	0.1	13.2	2.6	1	23	630	652	630	652	0.98
7	11	2.5	1.8e+02	3.0	0.1	5	16	660	671	657	673	0.84
8	11	1.6e-07	1.1e-05	25.6	1.2	2	23	683	704	682	704	0.96
9	11	0.0046	0.33	11.6	5.0	1	23	735	757	735	757	0.97
10	11	0.00054	0.039	14.5	0.7	2	23	762	783	761	783	0.96
11	11	9.6e-05	0.0069	16.8	0.3	2	23	788	810	787	810	0.95

Sequence Information

Coding Sequence: ATGGCGAGTCAACAGTACTCGTTACGATGGAACAACTATGTACGGCACATGACAAGTGCTTTCGAATCTCTACGGAGTGACAAAGACCTGATCGATGTCACGCTCAGCTGCGAAGGAAAGAAAATCCCAGCCCACAAAATGCTGTTATCAGCGTGCAGTTCCTATTTCAAAGACTTATTCAAGGAAAACCCTTGCCAGCACCCTGTTATAATTTTCCGTAATGTCACATTTGTTGATCTCGTGGCGTTGGTCGACTTCATGTACAATGGAGAGGTCAACGTGGAGCAAGAACAGTTAGCATCATTCCTCAACACTGCTGAACTGCTTCAAGTACAGGGTCTCACAAACAGCAGTAAAGATCAAGAGAAATTTAGAAAGACTGCCAAAGAGGACGACAGAGTACCTGGTTCCAGTTCTCAATTTGATGAAGATGGCGAGGAAAGAACGACGACGCCAACTAGAACAGGTCCTCCTGCAGccaagaaaagaaaatggcaGTCGCCAAGCAGAACAGAAAGTCCAGCTGCTCTCCTCGAGTCCCAAACTGCGCAAGTGAGTTCTGGTGGTGACGAGGATTTGCAGACTATTGATCAAGTGCCTTTAAAAACTGAAACGCCAGAATATGATGATGAGGATGACGTGCAAGCGGAATCTGGAGGGGAGGACACAACTGATGAACAAGATATTGTCCAGAAAATCCAGAAAAGTGATCAGCTGGTGTTGACATCTAACAGAAATAGGACTTCCAATAATGAACACTCGCTTTTCGGCAACAATTCTATGGATATGGACTCTGGTGATATGAGCAGTTTTGGTATGGCTGGACCATCAAATGAAAGCATGGGCCAAGATGGAATGCAAGAAACGGTCGACTACCCAGGTGTGTTAATAGATATGGCAGCTAAAATGTTTAGCCCGCGACCGGAGTTTGAACCACGCATCGTGCCTCTGGTCGACGGGACATATTCATGCAGCCTCTGTAATAGGACTTACATCAGCAAGATGCTTTGCAAGTCTCACCTCGCGTATCATCTGGGGAAAACGATGTGCCATATCTGCGACAAGGTTCTCTCCTCTATGCTTAATCTCAGACGCCACATCAACAACTTGCACGGAGAACAAAGTCCTCTCGCAATGAAGATTCCCTGTAAAATTTGTCGCAAGATGATGGtccctctctctctatctTGCCACATCAAACTGAAGCACAAGATTGACCCTGATGTTCTCAAATTGAACCTGGACCCAGTTGTGCTCTTGGACAAAGAAGAACTAGCATCGGAGCTCGCCCGAAGAGCAAATCTCTTAGAAGCAGAGCCTGAGGGCAGGCCTGCAAGCGTCGTTTACAAGGGCCATGgggtttgcaaaatttgctccAATAGGAAGTCATACCCCGATGAAGATCTCCCGGTCGCATCAGACATGGTGGCAATTCATCACAGCATTTTTTACGCGGGGGCCAACGCGGACGTGTCCGAGATGAAAGCGACAATGCGAATTATCGAGAAGAACGATAAATTCATTTGTAGCTTTTGCGAGCGCGAGTTTTCTCAGAAGGAGAGTTGTCGGTCACACATGGCGTCGCACTTGGGCAAAACAACGTGTAACATTTGCAATAAGTCATTCAGTCGAATAAATGAACTGAACCGTCACCTGGCCGTGCACGAGGGCAAAACGGTGTGTAAAATATGCTGCAAGGTGCTCAGCAGCGGCAAAAGTCTGAAGCGTCATCTCATTTACGTGCATGagcTTGTGTCTCCATTCAACGAAGTGTCAGAGCCGAACGAAAATATTAACTTCGTCTATACCGATGCCGATCCTCTTGCGATTGATGAACCGaggaattttattaacaaagaCGAGTTGGTCAGCAACCAGGACGGCCGATACTCCTGCAGCATATGCAACCGCGACTTTGCTTCTCAAAGGCTTTATCATTCGCACCTTGACAAGCACCAAGAGTTGACCCCTAGCATAAAGTGCAATAAATCGTTCAGCACAGTTAGAAAACTCAACTTGCGCATGGCGAATCGCCGAAAGACGCTCAAGTGCAATAAATGTGGCAAAACGTTTAGCACTTCCTCTTTGCTCAGACAGCACTTGGACATACACAAGGATGGACCGGATGTGCATTTCCTTTTGTCCGGCGGGTACGAGTCGGCGCCGGCGTCGTCAGGCAAAATCATTTCGTCCCAGGGCAAATTCATTTGTTCAGTGTGCAATCGCACTTTCTCGCACAAGCGGTCGTGTTGGACACACATGGCCATGCACAACGGCCGCACCACGTGCTCCGTTTGCCAAAAGACGTTCAGCAGTTTGTCCATCTTGAGAGCGCATTATGCGAAACACGAGGGCAAAACCGTGTGCTCGATCTGTAACGTGAGCGTCAGCACGGCCAAAAGCTTGAAACGCCACATGACCAGCGTTCACAACATCCCAGCAGACGAGTCCAGCTCGTAG
Protein Sequence: MASQQYSLRWNNYVRHMTSAFESLRSDKDLIDVTLSCEGKKIPAHKMLLSACSSYFKDLFKENPCQHPVIIFRNVTFVDLVALVDFMYNGEVNVEQEQLASFLNTAELLQVQGLTNSSKDQEKFRKTAKEDDRVPGSSSQFDEDGEERTTTPTRTGPPAAKKRKWQSPSRTESPAALLESQTAQVSSGGDEDLQTIDQVPLKTETPEYDDEDDVQAESGGEDTTDEQDIVQKIQKSDQLVLTSNRNRTSNNEHSLFGNNSMDMDSGDMSSFGMAGPSNESMGQDGMQETVDYPGVLIDMAAKMFSPRPEFEPRIVPLVDGTYSCSLCNRTYISKMLCKSHLAYHLGKTMCHICDKVLSSMLNLRRHINNLHGEQSPLAMKIPCKICRKMMVPLSLSCHIKLKHKIDPDVLKLNLDPVVLLDKEELASELARRANLLEAEPEGRPASVVYKGHGVCKICSNRKSYPDEDLPVASDMVAIHHSIFYAGANADVSEMKATMRIIEKNDKFICSFCEREFSQKESCRSHMASHLGKTTCNICNKSFSRINELNRHLAVHEGKTVCKICCKVLSSGKSLKRHLIYVHELVSPFNEVSEPNENINFVYTDADPLAIDEPRNFINKDELVSNQDGRYSCSICNRDFASQRLYHSHLDKHQELTPSIKCNKSFSTVRKLNLRMANRRKTLKCNKCGKTFSTSSLLRQHLDIHKDGPDVHFLLSGGYESAPASSGKIISSQGKFICSVCNRTFSHKRSCWTHMAMHNGRTTCSVCQKTFSSLSILRAHYAKHEGKTVCSICNVSVSTAKSLKRHMTSVHNIPADESSS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00344338;
90% Identity: iTF_00344338;
80% Identity: iTF_00344338;