Basic Information

Gene Symbol
-
Assembly
GCA_949628265.1
Location
OX451261.1:26699008-26705974[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 27 2.9 2.1e+02 2.8 0.4 2 23 161 182 160 182 0.95
2 27 0.00012 0.0089 16.5 0.2 3 23 216 237 214 237 0.92
3 27 1.1e-06 7.8e-05 23.0 1.2 1 23 257 279 257 279 0.98
4 27 0.94 68 4.3 1.1 3 23 334 355 333 355 0.92
5 27 0.015 1.1 9.9 0.4 3 23 361 381 360 381 0.97
6 27 3.7 2.6e+02 2.4 0.6 2 23 402 424 402 424 0.93
7 27 0.083 5.9 7.6 1.2 1 23 428 451 428 451 0.93
8 27 0.074 5.3 7.8 0.0 3 21 511 529 509 530 0.92
9 27 0.011 0.76 10.4 1.7 3 23 544 565 543 565 0.94
10 27 0.0028 0.2 12.2 2.7 2 23 570 591 569 591 0.96
11 27 2.3 1.7e+02 3.1 3.3 1 21 599 619 599 620 0.94
12 27 0.0001 0.0074 16.7 5.5 1 23 655 677 655 677 0.97
13 27 3.5 2.5e+02 2.5 1.4 1 23 681 703 681 703 0.92
14 27 0.019 1.4 9.6 0.8 3 23 740 761 738 761 0.87
15 27 0.2 14 6.4 0.8 1 19 838 856 838 856 0.96
16 27 0.011 0.78 10.4 0.3 3 23 863 884 862 884 0.94
17 27 0.019 1.3 9.6 1.1 2 23 889 910 889 910 0.96
18 27 0.075 5.4 7.7 2.6 1 23 926 948 926 949 0.94
19 27 0.1 7.4 7.3 2.5 3 23 1141 1162 1140 1162 0.92
20 27 0.0064 0.46 11.1 3.1 1 23 1240 1263 1240 1264 0.94
21 27 0.0071 0.51 11.0 1.6 3 19 1297 1313 1295 1316 0.93
22 27 0.025 1.8 9.2 0.0 2 23 1347 1368 1346 1368 0.97
23 27 0.047 3.4 8.4 0.9 1 14 1376 1389 1376 1394 0.88
24 27 0.0077 0.55 10.8 0.0 1 23 1399 1422 1399 1422 0.96
25 27 0.00095 0.068 13.7 0.3 2 23 1467 1488 1466 1488 0.97
26 27 0.016 1.1 9.9 5.6 1 23 1506 1528 1506 1528 0.97
27 27 0.047 3.4 8.4 0.2 1 21 1531 1551 1531 1552 0.94

Sequence Information

Coding Sequence
ATGGTTGAAGAAGATACCCAGGACATCAACCAATCTCAAGATGTTGATTTTGTCAAAGAAACCAGCAACCGATCTGAGACTGCTGGTCAAAATATTAGTGAGAGTGCTGATGAGTTCCTGCTTACTCCTTCCCTCTCTTCAGAACTTGAAGAATTTACTGGGTTTGAGAAGCAAGCGGGCGACGCAATGACCACTAAAAGCAGAGCACTTTTGAAGACTATAAATCAAAACAAGTTCATGAAAGTAGCATACAGTGGTCTAAACTACTTATACAAAACTGAGAAACTGGCTGAGTCTTTCAAAGAGTTGGATGAAAACTGCCTCGAAGATAGCATGCAACAGTGCCAAGGATGCCACTTCAAAATGAGCAATCCCAGAAGTCCTCACAACTGCATCCCAAACTTCTGCATCGCCTGCCAAGTGGATGCTGGTGCAAATTTCTCCGTGCATCTGCTGGAAGAGCACATTAATCTTACCAAAACGTGCCCTTTTTGTCTTGAAGAAATGGCCAGTCTGCACCAGTTGGTGGCACACCTGGAAAAGCACACCAGCATCAAGTTGCGTCCAAGCATTTGCATCAGCTGCAAAaccaatttcaaaactttagaAGGACGGATATTGCACAAGTGTCCAAACTCCAGCATTTGCAATATTTGCAACAAAGTGTTCAAATCTGAGGACACACTGAATGAGCACGTGGAGTTGCAGCACAAAGCTGGCTCAAACACAGTTGCAGACCAAGGACCATCTATAAAAGCGTCCAGCAAGTTCTCCTGCAATATATGTGACAAGCCATTCACAACTCAGTTCACGTTGAACTTGCATATGAAAGAGCACTTCAATGCTACAGAGAAAGAAGATAAAGTTGATAAAACTAATTGCAGTGCTGACAGGCTTCGTATTTTGCAAACTGCCCAGAACATAGTGAAATGCCCACATTGCGCAGTTTTCTACTTGAATATGAAAGTTCTTAGTGACCACTTGAGCCAAGTAAAGTTCTGCAAACTATGTCTCACTCAGCTGAGCACAAACCATGAATTTGAGGCCCACATGGTTGAGTATCACTGCTTTGAACGAATCTGCCAGTTCTGTGATGACGAGTTCGCTAACTGCGAGGAGTTGATCAAACATGTCAGGGTGCATACACTATTGACAATTCGGCCTTATTGTTGCACCCAGTGCAAAGGGATCTCCACCAACCCTGTTTGCAAAACATGCAATGTGTACTTCCAGAGTGACAAAGCTTTTGAAATGCACTGGATCAAAAAGCACAGCTTAGAGTACCTTTGTCCTGTGTGCAAACTGGACACAAGCACCTGCTCCAAGCTTCTGACCCACGTCCAGCAGGAGCACGCTGCGGATGTGGTTATTTCTTTCCTCTGCATCAAGTGTGACGAGACGTTCAAAGAAGATGCAGGTTATGAAGCTCACAAGTGTGTGATAGACGCACCTGAGCTCTCCAACTACCCCTGCTCAGATGATCAGTCTGAAAACGAATGCAGCCTTGACGACGACTCTAGACCATTAGCTTGTGCGATTTGTGGCAAAGAGTTTGAGTTATTGGAAGCTCTGGACAAGCATATTGCCATGACGGTTGAGGAAGCAACTTGCATCGCTGCGAGGAAGCACTGCAGCTTTTGTGACGTGTACTTTGCAACAAGGTCTAGCTTTGAGAGTCACATGATCCAGCAGCACCTGTCGGCCATGAAGTGTCCCTTTTGCCTCAAGTTCTTTGCGACCAAGTTCTCCCTAGAGCAGCATCTGTTGCACCACACCAATCTTCACAGGAGCGAGTTCTACTGTAAAAGTTGCAGAAGAATTTACTTCTCCCGAGGCCTCTTTCAGAGCCACCTGTGCTTGTCCGATGAGGAGTCTGAGAGCGATAAGGACGTTCTGATAACCTATTCACCTCCAAATCAGAAATCAAAGGAGGTTCTTCCTGCAACTAGAGCAAAAAACTGTCATGAATGTTTCATCTGCAAGAAATCATTTGACTCTAAACACCAGCTGAACATTCACTTGAAGAGTCACAAAGAGACTTTTAGCTGCAAAATCTGCAAGCAACACGTGAGTGGCATCAAGGCTATTAGAGACCACTTTCAAATGCACAAAAGCCTATCCGAATCTGTAAAATCTCAAGCTGTTGCAAAAAGCGATGCCCTCATGTCTCCTACCATTAAAATGGTTAAGTTGCAAGTTCCTGATGAAGTGAAAAAGTGCCTTCCTTGTCGAAGAGTTTTCAAAAGTCAAGAGGATCTGAACAAACATAAAGAACTGATTCACTCGTATGCGTCAAAAGCCAAAGATGATACAGATCGCACTCACCTGAATTGCAAATTCTGTAAAATTAAGCTGGAGTCCAATTTCTGGGTCGCGTTCCACTACACCAATCAGCACAACATCATGACCAGCCTGAAGTATCAATGCCAGACTTGCAAAGTGGTAATGCATACGACAACAAAGAGAGGCCTACCAATAAACCATCTACAAATCGACATGTACAACCTGGAGCACCCCTGCTCACATTGCAGTGATGTATTTGTCAACCAAAAGTCGCTCCTTGCTCACTGTGTCAGCGTGCGCTACTGTTTGAACTGCCTCATAGTCTTTAAAGACAAAGACAAGTACGAGCAGCACATGATGTACATCCATGCCAACTCGCGGGAGTGCGTGTTTTGTCGACTGGAGTGCAAAACCAAGGCTGACTTGATCCAGCACATAAAAGTGCACACTAAACTTTATTTCAGAACAAGTGAATCAATCAGAGGCAGGGTCTTTGCCTGCCGATGGTGCAAGATGACGTTCCAAAAAAGCGGATCCTACGAGAAGCACACCTTGGAACATCACCTTGGCAAGAGCTGCCCCTTTTGCGACAATACTTTGCCTCCGACGTCTGCCAAAAAGTTAGCCCATTTACAGGAGCACACAAATTTAGATGTTAAGAAACTTCTGGCCGAAGCTGTGGAGAAGAAGGCAGCCGCTCAGTTAAAAGAGAAGCAGGCTTCCGAATTAGCTGCAAAGAAAATGGAGGCAAAGAAGAAGGCTGCCGCTGCTGAAGCGCTCAAGAAAGCCAATGAAGAAAGAACTAGAAAAAAGGCAACCACCCTGGCGACCAAAATTGCAAGTAAGACTGCTCCCAAGCCTGTCGAGAAAACTCCTTACAGGGCTTCTTTGAGAACTGCTACCAAGTCAATGGAGAAAACTGCTGCCAAGTCGGAGGGGAAAACTTCCTCCAAGTCAATGGAGAAAACTGCTGCCAAGTCGGAGGGGAAAACTTCTTCCAAGTCAATGGAGAAAACTGCTGCCACGTCGGAGGATAGAACTGCATCTAAGAAGGTGGAGAAAACTGCTTCCAAGACCCCCGAGAACCATGGTCAGGCAGCGGGAAAAGGTTCCAAGGCTATTTTCCAAGGTGATCTGTGTCTGCTCTGTAAAAAGAAATTCAGATCCTCTGCGCTCATGTTCCACCACGTGATGGATTTCCACTACAACAACTCTAAAAAGTGCCCATTCTGCCAAAAAAAATGGACAAACGTTGGCAACACCAAATCACACATTCACCATTATCATAAAGTGAGGATGACTAGAGTAGATGATGTCCCCGAAGAAACGCCTGTAGAAGCGCCTTCTCCAGATCTTCCCACTGAACCAAGTGTCCATCATTCAAATAAAGTTCCAAGCCTGGGGTCTGGCAGCTCGTCCTCAAAAGATAGGGTATACAGCTGTTGCATCTGCAGCAAGTCATTCACCAACCAAAGTATTTTGGACAGCCACATACTTAACGTTCATCACATGGAATCTGCCAAagcGCAGCTGCTGGGAAAAATAATGGCATCTACCCCTGCTGATCCAGAGCCATTTCCCCAGGGTCCAAACAAGAAAACGTTTTGTTTCCATTGCCACACCAGCTTCAATACTGCGACTGAACTTCGAGCTCATGGAATAAAGGCTGGAGTCTTCTGCGAGTTCTGCTGTATCACTCTTCCTGACAGCAACGAGTACGAAATGCACATGCTGGAGGAGCATCCCTCAGAGGACACCTGCCAGTTTTGCGGTGCCTACATTCCTAACAAAGCTGGCCTTGAGATCCACATTCGAAGGCACACAAAAATTGGGCCGATCCACTACAAGTGCTTCGGCTGCAATAAAATGTTCACCAGCAGCAGGGCCAAGGATGAGCACCCCTGCATAGCATTTGCATGTCCAAAGTGCGGAGAGGAACAGAGTAGCCCTGATGGCTTAGAGAACCATCTTTCCACGGCACACATGGAGCAGCAAGTTCAGCCAACGCCAGCCGCAGTGGAAGTTGCCATAGCTGTTGAAGTTCCACTGACAGAAAAACGTGTAGGCAAAAGGAAGCAAACCCAGTCTGTTGAGTCAGACTCAGCACCAAAAGTTTATTGCAAAgagtgcaaattaatttgcagttCGCCTGAAGCACTGGCTGAGCACATCAAGACCCACAACGTAACTCCGTTGAATGTTGAACAGACCGCGGCTCCTGCTGCGGAGTACTTTAAGTGCAGGTACTGCGGTGAGCAATGCAAAAGTAACGTTGAATTGAGGGAACATCACTTTTCGCATGTCGCGTTCAAATGTCCAAAGTGCGCGGCAGTGTTTAACACTAAGCAGAAAATAATGGACCACCTAAAGCTATGCCAAGAGCCTCAGCAGTCTGCTGCGGTAATCAAGGTAGAAGAAAGTGATTCGGACTCAGACATCGTGATCCTTGATGGAGATGTAGAAGTTCCGCAATATGTCATTTTGTaa
Protein Sequence
MVEEDTQDINQSQDVDFVKETSNRSETAGQNISESADEFLLTPSLSSELEEFTGFEKQAGDAMTTKSRALLKTINQNKFMKVAYSGLNYLYKTEKLAESFKELDENCLEDSMQQCQGCHFKMSNPRSPHNCIPNFCIACQVDAGANFSVHLLEEHINLTKTCPFCLEEMASLHQLVAHLEKHTSIKLRPSICISCKTNFKTLEGRILHKCPNSSICNICNKVFKSEDTLNEHVELQHKAGSNTVADQGPSIKASSKFSCNICDKPFTTQFTLNLHMKEHFNATEKEDKVDKTNCSADRLRILQTAQNIVKCPHCAVFYLNMKVLSDHLSQVKFCKLCLTQLSTNHEFEAHMVEYHCFERICQFCDDEFANCEELIKHVRVHTLLTIRPYCCTQCKGISTNPVCKTCNVYFQSDKAFEMHWIKKHSLEYLCPVCKLDTSTCSKLLTHVQQEHAADVVISFLCIKCDETFKEDAGYEAHKCVIDAPELSNYPCSDDQSENECSLDDDSRPLACAICGKEFELLEALDKHIAMTVEEATCIAARKHCSFCDVYFATRSSFESHMIQQHLSAMKCPFCLKFFATKFSLEQHLLHHTNLHRSEFYCKSCRRIYFSRGLFQSHLCLSDEESESDKDVLITYSPPNQKSKEVLPATRAKNCHECFICKKSFDSKHQLNIHLKSHKETFSCKICKQHVSGIKAIRDHFQMHKSLSESVKSQAVAKSDALMSPTIKMVKLQVPDEVKKCLPCRRVFKSQEDLNKHKELIHSYASKAKDDTDRTHLNCKFCKIKLESNFWVAFHYTNQHNIMTSLKYQCQTCKVVMHTTTKRGLPINHLQIDMYNLEHPCSHCSDVFVNQKSLLAHCVSVRYCLNCLIVFKDKDKYEQHMMYIHANSRECVFCRLECKTKADLIQHIKVHTKLYFRTSESIRGRVFACRWCKMTFQKSGSYEKHTLEHHLGKSCPFCDNTLPPTSAKKLAHLQEHTNLDVKKLLAEAVEKKAAAQLKEKQASELAAKKMEAKKKAAAAEALKKANEERTRKKATTLATKIASKTAPKPVEKTPYRASLRTATKSMEKTAAKSEGKTSSKSMEKTAAKSEGKTSSKSMEKTAATSEDRTASKKVEKTASKTPENHGQAAGKGSKAIFQGDLCLLCKKKFRSSALMFHHVMDFHYNNSKKCPFCQKKWTNVGNTKSHIHHYHKVRMTRVDDVPEETPVEAPSPDLPTEPSVHHSNKVPSLGSGSSSSKDRVYSCCICSKSFTNQSILDSHILNVHHMESAKAQLLGKIMASTPADPEPFPQGPNKKTFCFHCHTSFNTATELRAHGIKAGVFCEFCCITLPDSNEYEMHMLEEHPSEDTCQFCGAYIPNKAGLEIHIRRHTKIGPIHYKCFGCNKMFTSSRAKDEHPCIAFACPKCGEEQSSPDGLENHLSTAHMEQQVQPTPAAVEVAIAVEVPLTEKRVGKRKQTQSVESDSAPKVYCKECKLICSSPEALAEHIKTHNVTPLNVEQTAAPAAEYFKCRYCGEQCKSNVELREHHFSHVAFKCPKCAAVFNTKQKIMDHLKLCQEPQQSAAVIKVEESDSDSDIVILDGDVEVPQYVIL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-