Cdip008566.1
Basic Information
- Insect
- Cloeon dipterum
- Gene Symbol
- ZFX
- Assembly
- GCA_949628265.1
- Location
- OX451261.1:11015932-11020268[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.22 16 6.3 4.7 1 19 279 297 279 302 0.95 2 14 2.3 1.6e+02 3.1 0.0 2 23 306 328 305 328 0.91 3 14 0.017 1.2 9.8 0.1 2 23 331 353 330 353 0.95 4 14 6e-05 0.0043 17.5 0.9 2 23 360 381 360 381 0.92 5 14 0.00014 0.01 16.3 3.5 1 21 387 407 387 408 0.92 6 14 6.7e-07 4.8e-05 23.6 1.7 2 23 420 441 419 441 0.98 7 14 6.3e-06 0.00045 20.6 2.0 1 23 447 469 447 469 0.98 8 14 3.8 2.7e+02 2.4 0.7 1 20 504 523 504 527 0.71 9 14 0.0022 0.16 12.6 1.7 1 23 549 571 549 571 0.95 10 14 5.4e-06 0.00039 20.8 3.3 1 23 623 645 623 645 0.98 11 14 0.00021 0.015 15.8 0.3 1 23 651 673 651 673 0.98 12 14 0.034 2.5 8.8 2.1 1 20 679 698 679 701 0.88 13 14 0.0095 0.68 10.6 4.0 1 23 705 727 705 727 0.97 14 14 0.026 1.9 9.2 0.8 1 23 739 762 739 762 0.91
Sequence Information
- Coding Sequence
- ATGCCGACGTGTGTGATTCGCGGTTGCAAAAATAGACCAGAAATGGTCCAGCAAAACAGGCAGAACAACAAACTTCAGTTGACTTTCCACAGGTTCCCTCTGATGAACCCAGAAATGATGAAAGTGTGGATGCAAACAATAGGcaccaagaatttaaaaagccCAGAGTGTCCAATTCACAAATGCTCCATAATCTGCTCCGATCATTTCGATccaaaattcatcaaattttctgGAATGCGCACGCGACTGGTACCTGAAGCCATTCCTACAATTTTTAGATACACCACTGCATATCAACCACAAATAAAGGCGCAAGAAATAACTGGCAGTAGTTCCATCATTTCAATATCGAATTCAATCTCCACCATTAGTGAGACTGGGCCATTCGCGATTCCCATTGAAGAGATAGGAAAGCAAAATGTTGTGTGCGTCGTCGGCATCAATTCTGGAGAACAGCCGAGTGTCAAAATTTTAGACCCAGTTAGTGTGGAGGGCTCAAACAAGTTTGAAGATCTCTGCCGAGTGTGCCTTGGAATGTCACCTTTGATGAcgcctatttttaaaaacggaaCTGATCTGGTTAACAAGATTCACAAACATCTGTCAATCAGGGTTTGCCAGGATGATGTACTGCCAATGAAAGTGTGCTCCAAGTGCATAAAAATCCTTGACACGGTAGAAGAGCTTTCAGCGTTGAGCTATGAAAATGAACTGAAGTTAAAACTGGCTCTAGAAACAGACAAAGAAATTAATCAGATCAGCACAGTGAAAAATTTAGTTCCTTCGGCAGAAGTCACTAAAAAAGAGATTGAGAAGGAAAGTGAGCAGATCTTCCATTGTCTAGACTGTGGCAAAACCAGCTCCAATTTTAAGTCGTTTGCTCGCCATTGCTATGCTGTGCACAAGAGGAAAAAGTGCAAGTGGTGCAATGCCTTACTCGCAAATGCGGAAGAAATGGAAGCGCATAGAATTGAAGCGCACGGCTCGAGTTGTGAGGCTTGTGGTGCCAAGTTCAAAGGAATCAACGCGTTGCTCAGGCATATTCGCCAGCAGCACCCAGATTTCAAGTCAAACACATGTGAGATCTGCGGTAAAAGCTTTATCAGCAAGTATAGCCTGGCGGTGCACTGCCAAATCCACAATACCAACACGCCGTTCCTCTGCGATTCGTGCGGCAAGAGTTTCAAGAGCAAGCAGAAACTGAAAAAGCATATTTGCAATCCAGAGGACGAGATGGAGGTTCGCAGCAACAACAAGTGCAACATATGCGGCAAAACCTACACGTTCCGCTCGTCCCTGCAGAGGCACCTCATCCGACACACTGGCAACAGGAGGTTCCAGTGTCACAAATGCTCCAAAAGCTTTTACGGTGCGGTCAATCTCAAGAATCACATGGTTGTGCATGAGAAATCAACTCTTTTCGAGTGTCAAATGTGCTGTGCAAGGTACTACCACAAGAGGAATATGATCACTCACTTGAAGGACAAACACTCAACACAGTGGAACTACAAATGTCCGTACTGTGTCAACCTGTTTGCCTCAATTGATGAGTGTGTGCGGCACAGAGACGAGGCTCACGGAAGCGAGCATAAGGAACAAGGCGTGGTATCAGCCCAAAAAGACGATGttgaatttgaggaatttaGATGCAAAATATGTGACAGACTGTTTGAAAACATCTACGCCCTGACGCACCACTTCGAGGAGCACGTCATGCACGGGCCAGAAGACCTGAACATCAAAACCATTGGGGTGGACGGGTTGCTGGAGTGCGCGTTGTGCGGCGCCAACCTGACCTCTACCTGGGCGATGCGGTGCCACATCAAGAAAAGCCACTTGGGAGTCAGCCAGAAGGAACTGCTGCACACGTGCGACACGTGCTCGAAGCAGTTCGCGACCAAGAGCCAGCTGCGGCGCCACGTGATGATGCACACCGGCGaaaaacccttcagctgcGGCAGATGTGGCGCTGAGTTTAGGAACAGCACTGCACAGAAGATCCACATGCGAATCCACACCGGGGAGACTCCCTATCACTGCCAGAAGTGTCCCAAGCAATTCCGCAGTAGCGCCATCCTCAGGAGCCACGAGGTCTTCCATGCCAGGCCTTTTAGCTGCAACCTGTGTTCGCAGAAATTCTCATGCAAGTCGGCGCTGAAGTCTCACTTGAATTTGCACAATAAGGACGAAAGTGAAGATAAGCTGGTGGTGTACAAATGCCAGTTCTGCGATTTCATCAGCAAAAGCAGGTCCACAGTGAGGAAGCATGAAGTCATTGCCCACGTGGAAATTGACATTGAGGCTGACGTGAATTTGGAACAACTAGCAGGTCCGAATGTGGCGTCTGAAGTGCAGACGGATGAACATACTGAATTTGTGACAAATGTTGCAGCGACCTATTTTACTAtgtaa
- Protein Sequence
- MPTCVIRGCKNRPEMVQQNRQNNKLQLTFHRFPLMNPEMMKVWMQTIGTKNLKSPECPIHKCSIICSDHFDPKFIKFSGMRTRLVPEAIPTIFRYTTAYQPQIKAQEITGSSSIISISNSISTISETGPFAIPIEEIGKQNVVCVVGINSGEQPSVKILDPVSVEGSNKFEDLCRVCLGMSPLMTPIFKNGTDLVNKIHKHLSIRVCQDDVLPMKVCSKCIKILDTVEELSALSYENELKLKLALETDKEINQISTVKNLVPSAEVTKKEIEKESEQIFHCLDCGKTSSNFKSFARHCYAVHKRKKCKWCNALLANAEEMEAHRIEAHGSSCEACGAKFKGINALLRHIRQQHPDFKSNTCEICGKSFISKYSLAVHCQIHNTNTPFLCDSCGKSFKSKQKLKKHICNPEDEMEVRSNNKCNICGKTYTFRSSLQRHLIRHTGNRRFQCHKCSKSFYGAVNLKNHMVVHEKSTLFECQMCCARYYHKRNMITHLKDKHSTQWNYKCPYCVNLFASIDECVRHRDEAHGSEHKEQGVVSAQKDDVEFEEFRCKICDRLFENIYALTHHFEEHVMHGPEDLNIKTIGVDGLLECALCGANLTSTWAMRCHIKKSHLGVSQKELLHTCDTCSKQFATKSQLRRHVMMHTGEKPFSCGRCGAEFRNSTAQKIHMRIHTGETPYHCQKCPKQFRSSAILRSHEVFHARPFSCNLCSQKFSCKSALKSHLNLHNKDESEDKLVVYKCQFCDFISKSRSTVRKHEVIAHVEIDIEADVNLEQLAGPNVASEVQTDEHTEFVTNVAATYFTM
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -