Cdip011216.1
Basic Information
- Insect
- Cloeon dipterum
- Gene Symbol
- -
- Assembly
- GCA_949628265.1
- Location
- OX451262.1:2159322-2160434[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.0022 0.16 12.6 0.7 2 23 21 43 20 43 0.95 2 12 6.3 4.5e+02 1.7 0.1 1 23 50 74 50 74 0.85 3 12 0.00028 0.02 15.4 0.1 2 23 97 118 96 118 0.94 4 12 6e-05 0.0043 17.5 1.3 1 23 124 146 124 147 0.93 5 12 0.012 0.87 10.2 0.3 1 23 153 175 153 175 0.93 6 12 8.4e-05 0.0061 17.0 6.8 1 23 181 204 181 204 0.97 7 12 0.098 7 7.4 1.1 1 23 211 233 211 233 0.96 8 12 0.0068 0.49 11.0 0.0 2 23 239 260 238 260 0.93 9 12 5.1e-06 0.00037 20.8 1.7 1 23 263 285 263 285 0.98 10 12 8.3e-05 0.006 17.0 0.7 1 23 291 313 291 313 0.98 11 12 0.00062 0.044 14.3 0.3 2 23 320 342 320 342 0.97 12 12 0.012 0.84 10.3 1.2 1 23 347 370 347 370 0.96
Sequence Information
- Coding Sequence
- ATGCGCAACTCGACCTCACTGCGGTGCCACGTGTGGTCGCACTCCAAGGGCAAGCAGCTGCAGTGCCAGCACTGCAGCAAGGCGTTCGGCGCGCGCGTCTTCCTCTCGGCACACATCCGCGCCAAGCACCTTCGGCTCGAGCGGCCGTACGCGTGCACGCTCTGCTCGGTCCGCGCCTTCCGCGGCATCCGCGGCCTCGTGCTGCACTACGCGCGCAAGCACCTGCCGCGCCGGCAGCGCCACGCCGACCTCGACTACCTCTGCTGCTACGCGCGGCTCAACGTGATGCGCTGCGGCGCGTGCGGCAAGCGCTTCATCAACAAGGCGCAGCTGGTAGAGCACGAGGCGATGCACACGGGCGTCAAACGCTATTCCTGCAAAAAGTGCGGCCGCGCTTTCAAAACTGGCTCTTTGGTGCGCCGGCACGAGATCGCGCACCACGGCCGGCCGTCCAACTTCGTGTGCCGCCACTGCGGCCGCCAACTGGCCTCCACGCAGGAGCTGACCCTGCACGAGGCGGCCCACGAGTCGGTGAAGGCGTTCCAGTGCCACGACTGCAGCCAGCACTACAAGCACAAGGAGTCGCTGATGGCGCACATCCGGCAGCAGCACCTCGGCATGGCGCGGACGTACGTGTGCGCTGCCTGCGGCTACCACACGACCAAGCGCAGCCGCTACGAGACGCACGTGCTGCTGCACGAGCCGCGTTCGCTGCCGTGCGACAAGTGCGACGAGGTGCTGCCCGACGAATACTCGTACCGCAAACACGTCGATTGGCACCGGCCCTACCCGTGCGATCGCTGCGAGAAGCGTTTCGACGCCAAACACAATCTCAACATGCACATGCGCGTGCACGAAGGCGGACAGTCGTTCACGTGCGGCGTGTGCGGACGCACGCTCATGTCGAGCACGCGGCTGCGCATCCACATGCGCTACCACACGGGCGAGGAGCCCCGCCAGTGCACCCTGTGTCCGGCGTCCTTCAAGGAGATCACGCCGCTCAAGACGCACATGCGCAAAGTGCACAACGTCAAGCCGTACGCGTGTGAGCACTGCAACAACCGATTTGACTTTGTCAGGGACATGCGAGCTCACGTCAAGAGCGAACATTGA
- Protein Sequence
- MRNSTSLRCHVWSHSKGKQLQCQHCSKAFGARVFLSAHIRAKHLRLERPYACTLCSVRAFRGIRGLVLHYARKHLPRRQRHADLDYLCCYARLNVMRCGACGKRFINKAQLVEHEAMHTGVKRYSCKKCGRAFKTGSLVRRHEIAHHGRPSNFVCRHCGRQLASTQELTLHEAAHESVKAFQCHDCSQHYKHKESLMAHIRQQHLGMARTYVCAACGYHTTKRSRYETHVLLHEPRSLPCDKCDEVLPDEYSYRKHVDWHRPYPCDRCEKRFDAKHNLNMHMRVHEGGQSFTCGVCGRTLMSSTRLRIHMRYHTGEEPRQCTLCPASFKEITPLKTHMRKVHNVKPYACEHCNNRFDFVRDMRAHVKSEH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01046589;
- 90% Identity
- -
- 80% Identity
- -