Basic Information

Insect: Cloeon dipterum
Gene Symbol: PRDM10
Assembly: GCA_949628265.1
Location: OX451259.1:25048449-25054164[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2 1.4e+02 3.2 0.2 5 20 349 364 347 365 0.91

2 15 1.7e-05 0.0012 19.2 2.4 1 23 401 423 401 423 0.97

3 15 0.00054 0.039 14.5 0.1 3 23 472 492 470 492 0.94

4 15 0.02 1.4 9.5 0.2 2 23 509 530 508 530 0.94

5 15 0.00011 0.0076 16.7 2.0 1 23 545 567 545 567 0.98

6 15 0.17 12 6.6 1.2 2 23 576 597 575 597 0.94

7 15 0.00024 0.017 15.6 0.1 1 23 604 626 604 626 0.98

8 15 0.0005 0.036 14.6 4.6 1 23 632 655 632 655 0.97

9 15 1e-05 0.00072 19.9 0.1 1 21 660 680 660 681 0.95

10 15 5.7 4.1e+02 1.8 0.1 10 23 688 702 687 702 0.83

11 15 0.004 0.29 11.7 5.0 1 23 707 729 707 729 0.98

12 15 5.4e-06 0.00039 20.8 2.1 1 23 735 758 735 758 0.94

13 15 0.0091 0.65 10.6 2.1 1 23 791 814 791 814 0.97

14 15 0.0005 0.036 14.6 2.3 1 23 836 859 836 859 0.96

15 15 0.00047 0.034 14.7 1.8 3 23 899 920 898 920 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2	1.4e+02	3.2	0.2	5	20	349	364	347	365	0.91
2	15	1.7e-05	0.0012	19.2	2.4	1	23	401	423	401	423	0.97
3	15	0.00054	0.039	14.5	0.1	3	23	472	492	470	492	0.94
4	15	0.02	1.4	9.5	0.2	2	23	509	530	508	530	0.94
5	15	0.00011	0.0076	16.7	2.0	1	23	545	567	545	567	0.98
6	15	0.17	12	6.6	1.2	2	23	576	597	575	597	0.94
7	15	0.00024	0.017	15.6	0.1	1	23	604	626	604	626	0.98
8	15	0.0005	0.036	14.6	4.6	1	23	632	655	632	655	0.97
9	15	1e-05	0.00072	19.9	0.1	1	21	660	680	660	681	0.95
10	15	5.7	4.1e+02	1.8	0.1	10	23	688	702	687	702	0.83
11	15	0.004	0.29	11.7	5.0	1	23	707	729	707	729	0.98
12	15	5.4e-06	0.00039	20.8	2.1	1	23	735	758	735	758	0.94
13	15	0.0091	0.65	10.6	2.1	1	23	791	814	791	814	0.97
14	15	0.0005	0.036	14.6	2.3	1	23	836	859	836	859	0.96
15	15	0.00047	0.034	14.7	1.8	3	23	899	920	898	920	0.98

Sequence Information

Coding Sequence: ATGGAGACAGGTAGAGAACCGCCTGATGGTCTAAAAGTTGAGGATTGGGCTGCTGCAACTTCTTGTCAGTTGGGACAGGTTGCTTTCGTGGAAGGAGAAGGACAGTTTGTTACTTTCACGGAGCAGCCAACCGGGGACTTTGAGGATGAAGTCAGTCCCTTGGATCCCAACATGAGCTCAGTTGCTTGTTACTCTCCTGTGTACTCAAAGAACATGCAATTTTATCCTCAAACTTCAGACATTTGTGTATCATCATCCACCGGTCCTGTTGATGAGCaggcaacaattgaatttttggacgAGAAAAAGCTTGTGATGGATGGCAAGGTTGACTCGTCTGGTGATGAAGAACTTAGAGAAGTCCAAAGGTTTATAGCAACGAGTGCTGCACAATCATTTTTGGTCAATAATGGAGGAGGCATGGTACCAGAACAGCTTCTCGGTGCAATAAGAAATCGGTCTGATCGTGGCATGGAGGAAAAGGAAAGAGGTTTGGCAATCGCCCTATATGATGAAATGCTCAAGGAAATGGCTGAAGAAGAGGATAAACATCAAGAATGGctggaaaaagaagaaaacaaaGTGATAAGTGATGAGCCGGTTCAATCAAGAGCATGGGCCACTCTACCAAGCACATTCTTGTCCatcggaaaattaaataaaataccagGATATGGAATCTTTGCTCGTAAACCTATACCAAAGAAAACTCAGTTTGGACCCTTAGAAGGAGATATATTAAAGCAACCCAATGCCACATGTCAAGGACTGGAGCTGAGTTTAGAGCTGGAAGATGGTACTTTAGTGTACTACGACACATCTAACGAGAATTTGTCGAATTGGATGAAATTTGTGCGTCCGGCAAAGTTATATGAGGAAATGAATGTTGTTGTGGTTCAAATTAAGGACAGCCTTCACTTCATTACTACTAAGGCTATTCAGCCCAAACAAGAGCTGCTTGTTGGTTATAGTGAGCAATATGCTTCGTCTAGGAATTTATCCTTGTTGCAGCCACTTAATGagaattctgagaatgtacATAGTCATTGTGACAAAACGTTTCTATCATCTGAAGCAATGGAAGAGCACATGGTAGATCAACAGGAGAAAGCAGTACCTGTCAAACGCAAAGTACTCTCACATCTTCCCATCAAGAAGTGCAAATCTGAAGACAACTCGtctGGAGAAGAGACTGCAGAATTTAGATGCAATACTTGTTCAAGGAACTTTCCTCGAAGCTACAGTTTGAAGAGGCACTTGCTGCTCCACTCAGCTGATAAAAACATTAAAAAGAGCAGCGGCAAAGACAAGTCTGACAGGAATGTTctcaaacagaaaaatcaaagGTACATAGTAATTCTCATCACCTCCATCTTATCTGAAAGTTTAATTAGCAAGGAGAGTTTGTGGGCTTGCAACTATTGCCAGCTGTCTTTTGAGACCGCTTCAATGCTCAACCTTCACACATTGGCTCACGCCGCCGAAAATGTGGAGGAGCAGGATGCTGCGGAAGCGGAGAAGCAGCAATGTCCCCAGTGCAGCCAGCAGTATGAAACTAAGCGGGAGCTTGTCGAGCACACAGCAGCGCATGGCAAAAGCCTCAGGCGAAGAACAGTTAATCCGGAGAAACCGCACAAATGTGAGCTGTGCTACAAGTCATTTGCTACTGATGACCGACTGCAGaaacATATGCTTGTGCATGGAGCAGAGGAAACAAAACCACTACAATGCGAAATCTGTTTCAAACGATTCCTGAACAATTCCGCCCTAGCTTGTCACGTCAAAGTCCACACAGAGGagaaaaaagtttttgaatGTCCAATATGCAGGGAAGTGTTTGAGCAAGTGATAACCTTGAAGGATCATGTGCAAACGCATTGCAACAACGGAGTTTATACTTGCCCGCATTGCTCAAAGACGTTTGACGAGTACAATCACATACGGAAGCACATCCGCGCCTTCCACAGTGAAAAACGGTTTCCCTGTAGTCTCTGCGACAAAGTGTTTCCCAGACCAGACAAACTCAAACTACATATGCTCAGGTCAGCCATTTTGGCAGCATTTATTGGCTACAGTTTGGTGCGCAAGCACATCCGAACGTTCCACAGTGAACGGAAGCACACTTGCTCTTCTTGTGGAAAGTTGTTCCACACCCTCGACAAGTTGAGAATGCACATGCTCAGACACTCGGACCATCGAGAATTCCTATGTGCAAATTGCGGCAAGCAATTCAAGAGGAAAGATAAACTGAAAGAGCACATGAAACGAATGCACTCAAATGAACGAGAGGCTAAGCAAAAGCCAAGCAGACAATCACTTAGCAGGAAATTTATCCCGAAGGTTTCTCCCACTGACTATCATCGTTTCACATACAAGTGCCATCAATGCATGCTGGGCTTCAAGAGGAGGGGAATGTTGGTGAATCACTTGGCCAAAAGGCACCCAAGCATCAACCCAGACACAGTTCCTGAACTCAACTTGCCGATAATGAAAACAACCAGGGACTATTTTTGCCAGTATTGCGAGAAAGTTTACAAAAGCAGCTCCAAACGAAAGGCACACATCCTGAAGAACCACCCTGGTTCGGAACTGCCAATGAGCAACCGCCGCAAAGGTGGAGTGCCGGAGATTCCTGGCGTGCCGAACCCTACCTTCTCACAGACGGTGGGCAGCATCTCAACTCACCCACACGGATGTCCATGGTGTCATAAGCAATATGCATCCAAGGCCAAGCTGCTGCAGCACCAACGAAAAAAGCACTCGGATCTTGTTGCCGCCAATAtgGCTCATGCTTCTCAGAGCAGCTGTGTCAATTCTGAGAGCTCATCAGATTCTGATCCAAAATCAAGCAGCAAATTTTTGGTCAATGGAGAATGTCTCGACGTCATTCAGATCCAGGAAGCGTCGGGCAATCTTATTTCGGCTGTTGGTCTTTTGCCTGCTGGAGCTAGAAttgaatacCAAGTCACTGGTGACCAGGAAACTATCCCTGATGGCAGGATTTACATTGATACATCCGTTTTGAAACAACCACTGAAGGCATCTGGCACAGACATGCTGTCGCAAGCGCTCCTATCATCCGACCTGCTGACTGACGACTATGTGAAGGTGTACCACGCGGGCAACGTGGTCACCGAGGGAGCAAGCGAAGAAGAGCAACTGGTGGCGGTGACCAGCACACAGATCGAATCGTCACAACTACGCCAGCTGTTGCAGCTCGGGGGCGGCGAGGGTGGGCGCGAGTGGGCTGCCTACCCGGCACGCTGA
Protein Sequence: METGREPPDGLKVEDWAAATSCQLGQVAFVEGEGQFVTFTEQPTGDFEDEVSPLDPNMSSVACYSPVYSKNMQFYPQTSDICVSSSTGPVDEQATIEFLDEKKLVMDGKVDSSGDEELREVQRFIATSAAQSFLVNNGGGMVPEQLLGAIRNRSDRGMEEKERGLAIALYDEMLKEMAEEEDKHQEWLEKEENKVISDEPVQSRAWATLPSTFLSIGKLNKIPGYGIFARKPIPKKTQFGPLEGDILKQPNATCQGLELSLELEDGTLVYYDTSNENLSNWMKFVRPAKLYEEMNVVVVQIKDSLHFITTKAIQPKQELLVGYSEQYASSRNLSLLQPLNENSENVHSHCDKTFLSSEAMEEHMVDQQEKAVPVKRKVLSHLPIKKCKSEDNSSGEETAEFRCNTCSRNFPRSYSLKRHLLLHSADKNIKKSSGKDKSDRNVLKQKNQRYIVILITSILSESLISKESLWACNYCQLSFETASMLNLHTLAHAAENVEEQDAAEAEKQQCPQCSQQYETKRELVEHTAAHGKSLRRRTVNPEKPHKCELCYKSFATDDRLQKHMLVHGAEETKPLQCEICFKRFLNNSALACHVKVHTEEKKVFECPICREVFEQVITLKDHVQTHCNNGVYTCPHCSKTFDEYNHIRKHIRAFHSEKRFPCSLCDKVFPRPDKLKLHMLRSAILAAFIGYSLVRKHIRTFHSERKHTCSSCGKLFHTLDKLRMHMLRHSDHREFLCANCGKQFKRKDKLKEHMKRMHSNEREAKQKPSRQSLSRKFIPKVSPTDYHRFTYKCHQCMLGFKRRGMLVNHLAKRHPSINPDTVPELNLPIMKTTRDYFCQYCEKVYKSSSKRKAHILKNHPGSELPMSNRRKGGVPEIPGVPNPTFSQTVGSISTHPHGCPWCHKQYASKAKLLQHQRKKHSDLVAANMAHASQSSCVNSESSSDSDPKSSSKFLVNGECLDVIQIQEASGNLISAVGLLPAGARIEYQVTGDQETIPDGRIYIDTSVLKQPLKASGTDMLSQALLSSDLLTDDYVKVYHAGNVVTEGASEEEQLVAVTSTQIESSQLRQLLQLGGGEGGREWAAYPAR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -