Cdip016234.1
Basic Information
- Insect
- Cloeon dipterum
- Gene Symbol
- Bcl11a
- Assembly
- GCA_949628265.1
- Location
- OX451263.1:20397409-20403238[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.053 3.8 8.2 0.1 2 23 5 26 5 26 0.97 2 13 7.2e-05 0.0052 17.2 1.3 3 23 457 478 455 478 0.96 3 13 1.7e-05 0.0012 19.2 0.1 2 22 510 530 509 530 0.94 4 13 0.00012 0.0087 16.5 3.1 1 23 537 559 537 559 0.97 5 13 1.4e-06 0.0001 22.6 0.6 1 23 565 588 565 588 0.93 6 13 0.26 19 6.0 0.4 3 23 600 621 599 621 0.92 7 13 0.00057 0.041 14.4 7.0 1 23 626 649 626 649 0.96 8 13 0.0014 0.099 13.2 0.2 2 23 667 687 666 687 0.97 9 13 3.9e-06 0.00028 21.2 1.4 1 23 693 715 693 715 0.93 10 13 0.00011 0.0078 16.7 0.7 2 23 724 747 723 747 0.95 11 13 0.0098 0.71 10.5 4.4 1 23 753 775 753 775 0.98 12 13 2.6e-05 0.0019 18.6 5.0 1 23 781 803 781 803 0.98 13 13 0.00072 0.052 14.1 5.8 1 23 809 831 809 831 0.97
Sequence Information
- Coding Sequence
- ATGGACGATCCCGTGTGCCCTGTCTGCACTTTGTCCGTCCGCAAGGGCATCAGCCTCGAGGAGCACCTGAATACGCATCCCAAGGATCAGGTGATCCAAGCCCTGATCCGGAGATGCCTGACCTCGGCCCCGACAGCAGCCCCGCTGCAGTTCGTGTCGCCGGGATCGTACAACCCGTTCAGCCTTATCGTGCACCCCTCGGGCTTCCTCCATTACAACGCAGTGTCGGCGCCATTTGTGCCTCCGGGCCCGGTTTTCAATGCTCCCAGCCCGAGACCCAACCCCACACAAACACCACCACCAGCTCAAACTCCAACTGGCAGCACCTCAAACATCAATTTGTCAACCTCGTCCAGGTCTTCAGtggTCGTTGAGAAGGCTAAAGAAGAACctcttaaagaaaaaattgaagaaaccCAAAGTCCAtcgaataaaaatgaagaagaCGACGATGATGACATTGACGCGTCTTACGAGAGTAATGAAGAGGAGGAGAATGAAGGATTGCAAGAGAAAAGCCCAGTTCCTGACCCTACTAAAGAAGAAAACGCTGGCTCCTCTTCATCACCGCTGATGACGCATTGTGTCACACGCAACAACGGCACCATCGTTGACAGCGTCTACATCGAAGTCAAGGATGAACTGATGCAGCAGTGCAGAGACGCTCTTGAGGAACACGCAGGCACGGCGCTGGATTCGCTGCTCATGAAGGAGGGCGATGCCGAAATGCATTGCTCTGAAGTGTTGGACGCCAACTCTGATCGCTCTGACAGTCTTCAGGAGAGTCTGACTGTTAAGGTGCAGAACGATGCCGAGTATGAATTTGTCCTCGGCATCTCTAATGACGCGCATGAGGTCTCAGACCACTATAGCATTGGTCCAAATTCACCAAAgGACAACGCGTCTATCAGGGACATACAGACTGATGAAACGATGCCACCTCAGGGCGAACTCAGCGAACAGGAGAGCATTGGCGGAGATTCTGCCTCCTTGTGGGGACCTGCTGCTGAAGATGTGTTTTCTGCACCTCAGGTGTTTTCTGCCTTGACGATCCAAAGGAGGTCAGGAACGCCGCACATTTTGACTGAGTGGCAGCCTTTGGCTGCCGCGTCCCGACACTCTGAGGCAGCATCGTCCAGCACCTCAACCACCACTAATAGtATTCATTCGGACCATAAGATGGTGTTCTGTGGTACAATCGTAGACAGGGGCATTCCAATGGTGAGCGGTGGGGAACAGTGGCGACAGGTGGATCAAGATCTCAAACCGGCCGAAAATCAAGAGCCTGTCGAACCATCCAAAGTACTCATGACTGTGATGGGTGAAGAAACCCTTTTGGTAGAGCAGTCAGTCCGGCGGCAGCAAATCTGCTCAGTCTGCAACCAGACTTTCAACAGCTACCGTGAACTGCAGAATCATAGACGCAAAGAGCATCGAAAAACTAAGTATAAGTGCCCGATTTGCATTGTGCCATGTGAGTTTTCCGAGCGGAAGGATTATCTGGAGCACACTAAGTCTCACTCACTGGAGTGTCCACTGTGCGGAAAAACATTCAAGAACCTTCCCAGCCTGAGCCTGCACATGAAACGCGAAATGAACATCCGGCCTCACAAGTGCGAGATCTGCGAGAAGAGCTTCATCACCAAGCAGAAGCTCATGGAGCACTCCAACAAACACTCGGGCCTCACTCCCTACGAGTGCAAGCTGTGCGGCAAAGGGTTCAGGCGCTACAGCAATCTCATCCAGCATAGAGATTGGCTGCACCTGCGAAAGCGTAAGCCACCCATCGACCTCCTCTGCGGGATGTGTGAACAgATTTTCCACTCAAAGAAGCGTTTGGAATGGCACGTGGAGGAAGCGCACTTCCCTCAGCCACATGTGTGCGCGCACTGCCCGCAGCGTTTCACGCACGCCTCTTGCCTGACGCGTCACGTGCGGCAGCTGCATGACCGCAAATACCAGCCAGTGACCAAAGAAGGTATCAAGAAGGGCTGCAAGGAGTGCACCGAGTGTGGCGGCGTGTACTCGCGCACTTCGCTCGTTGTTCACATGCGCACCCACTCAGGTGTGCGACCCTTCAAGTGCAACATATGCTTTAAGgCTTTCACCACTCGTTGGAACTTGAATCAGCACATGTGGACCCACGAGTCGCCTGCTCAGCTTCCACTCAAATGTGATGTGCAGCAGTGCCGAAAGGCTTTCTACCGCAAAGAAGATCTCGAAGCACACAAACGCTCCCACACTAAACACAAGGCTTACACGTGCAACGTTTGCGGCATGAAATTCCTGCGCAAGTCAAACTGCATGCGTCACTACCGGGAGCATGTCAAGGACAAAGAACACACATGCGAAATCTGCAGCAAGACCTTCCACCGGTCGTACTACCTGGCCGAGCACCTGCGCACCCACTCTGGTGAGAAGCCCTTCGCGTGCCACATTTGCGGCAAAAACTCCACCACCAAGTCAAACCACAACAAACACCTCAAAACTCACCTCGGCAAGGAGCCTGTCACGCCGGAAAACTAG
- Protein Sequence
- MDDPVCPVCTLSVRKGISLEEHLNTHPKDQVIQALIRRCLTSAPTAAPLQFVSPGSYNPFSLIVHPSGFLHYNAVSAPFVPPGPVFNAPSPRPNPTQTPPPAQTPTGSTSNINLSTSSRSSVVVEKAKEEPLKEKIEETQSPSNKNEEDDDDDIDASYESNEEEENEGLQEKSPVPDPTKEENAGSSSSPLMTHCVTRNNGTIVDSVYIEVKDELMQQCRDALEEHAGTALDSLLMKEGDAEMHCSEVLDANSDRSDSLQESLTVKVQNDAEYEFVLGISNDAHEVSDHYSIGPNSPKDNASIRDIQTDETMPPQGELSEQESIGGDSASLWGPAAEDVFSAPQVFSALTIQRRSGTPHILTEWQPLAAASRHSEAASSSTSTTTNSIHSDHKMVFCGTIVDRGIPMVSGGEQWRQVDQDLKPAENQEPVEPSKVLMTVMGEETLLVEQSVRRQQICSVCNQTFNSYRELQNHRRKEHRKTKYKCPICIVPCEFSERKDYLEHTKSHSLECPLCGKTFKNLPSLSLHMKREMNIRPHKCEICEKSFITKQKLMEHSNKHSGLTPYECKLCGKGFRRYSNLIQHRDWLHLRKRKPPIDLLCGMCEQIFHSKKRLEWHVEEAHFPQPHVCAHCPQRFTHASCLTRHVRQLHDRKYQPVTKEGIKKGCKECTECGGVYSRTSLVVHMRTHSGVRPFKCNICFKAFTTRWNLNQHMWTHESPAQLPLKCDVQQCRKAFYRKEDLEAHKRSHTKHKAYTCNVCGMKFLRKSNCMRHYREHVKDKEHTCEICSKTFHRSYYLAEHLRTHSGEKPFACHICGKNSTTKSNHNKHLKTHLGKEPVTPEN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -