Cinc003665.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Clistopyga incitator
Gene Symbol
mecom-b
Assembly
GCA_947507545.1
Location
OX382190.1:653415-667974[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.012 1.3 10.0 0.4 2 23 227 249 226 249 0.95
2 8 0.00013 0.014 16.1 0.6 1 23 285 313 285 313 0.93
3 8 4.4e-06 0.00047 20.8 2.6 1 23 319 341 319 341 0.95
4 8 2.7e-05 0.0029 18.3 5.0 1 23 347 369 347 369 0.99
5 8 3e-05 0.0032 18.2 1.1 2 21 377 396 376 397 0.95
6 8 8.8e-10 9.4e-08 32.4 1.2 1 23 759 781 759 781 0.99
7 8 9.6e-08 1e-05 26.0 1.7 1 23 787 810 787 810 0.97
8 8 9.4e-06 0.001 19.8 3.4 1 23 816 838 816 838 0.99

Sequence Information

Coding Sequence
ATGAAGTTGTTTGTCACAGTCGTAGTTTTGGTTGTCGAAGAAGCCGAAGAAAGAGCAGAGGTGAGCTCCATGGAAACGAGTGAGAGAGTGATCATCGGTCAGACAAATCTGTCGCTCGAATTGTCCGCACATGTACGCGCGCATCTCGTCGCCGACAAAGCGAAAAAAAAGAAAGGTTCCCCGCTGCGCGACGAGGATCAGTTTTTCCGCTGCGCTCCAGTAGAACGAGCGAGACGAAAAATAGGGAAAACCTGCGGAGGCTGCGAGGACTGGGCCGGAAAAATTTCGGAAGAGGAGAGGAGAAATATCCCGGAGACCCTGAAGAGTGTCGCCGCCGAGTTAACGCATCATTGTCGCAAGGTGCGGATCGCTGGAAGTGGAGTCAGAGGATGGTTGGACGCATCCCACGAGGCAGGAAATTGGTTGAAATATGTCAGAAGTACAACGAATCCACACGCTGTTAACATGCGACACGTGCTCATCAATGGCCAGATGTTCTACGAGACCATGCGGGACATGTCAGCCAGTGAAGAGCTGTTGTTGGGTCTTCGGGAGCCGCTCCAACTGCAGGACATGTTAGGCGAGAATACGACCGAAGACAGAAGCGATCGGGAGACCGCCTCGCAACACAGCGGAACGGTCGACGAGGATCGCGAAGAAGAGGGTGAAGGTGAAATAAGGTGTACTGTCTGCGACAGGCCCTTCCAGGATATCGAACTGCTGGACAATCACCTGGTGACGTGTCATCGTTATCCCTCGGATCAGCACCGTTGCGAAAGTTGTCCAAGCGGTTACGCGTGGCGCCCTCTACTAGTGCGTCATCGCGCTATCAAACACGGCGACCTCCGGAAGTACTCTTGCGAAAATTGTCCCAAGTCTCAACCCCCGCAGGTTTTCACGGACCCTTCGAACCTCCAGCGTCATATAAGAGACCGTCACGTTGGTGCCCGGAGTCacgcttgcaccgagtgcggcaaaaccttcgccacaagttccggcctcaagcagcacactcacatccacagtagcgtgaagcccttccagtgcgaagtttgcttcaaggcctacacccagttctcgaacctctgtcgacacaagcgcatgcattcggactgtcgtatgcagatcaagtgcgtcaaatgcggacagtccttcagcacgagtacctcgttgacgaagcacaAGCGTTTCTGTGACTCGACGACCCCGGCGAGCGGCGCGATGCCGCAGTTGCCTCCATCGGGGCCCAGTCCCTATCTCGTTTTTCCACGGCCTCCCGTCTCTTTGCCCGGCTGTATGCCTTTTTATCCACCCTATCCTGGGATATTCCCGAACGGACCTAATTTCCTCAACGGCCCGCTTCTCTTCCCGCCCAAAGTTCAACAGCAGCAACAGCACCCAACCGAGCAGGCTGACAAGAGAAGCGAGAGCCCGAAGAAGGAGAGATTCACGCCACCTAGGTTACTGCCACAACACAACAAGGTCTCGCCCTCGGCCGCGGAGGAAGCGACATCGACATTCAGACCTTCCCCGGCGAGGCCTCCGATTCAATCGACTCCGGACACGGACGACGACACCTCCAGACGGAGAGACACCGGTCAGAGGCAGGAGAAGAGGATGAAGATGACGGAATCCGCTGGCCTGTCTTCGAACGAGACGTCCACGGATCAGCCTCTCGACCTTAGGGTCCAAACGAAAAGGGACGACGAGGCTGGACCTCCGACTTCGCAGGCTAATGACGCCCGAAGTCGGACTCCTTCACCAACCCCCGCACCCATGGAAGAGTCCGCGACCGAAGCCTCGAAACATTCCGAGGAAGAAGACACCACGATGGATGTCAGCGAGGTCAAAGAGGAATCCAGCTTGCAGTTACGCACCACCGCGACCCAGGAACAACCACCCCCAAACACCCCTCCCTACATGGCCTATCCTCGGCCCATTCATCCCCAAACCCAAGCCATGTTTCTCGAGGCCATGTATCGGAACACCGGAGGCACGGGGTTTCCGGGTTTTCCAGGAGGACCCCAAGCTCCCGGTTGCTCCCCGGAGTCCCGTTTACTTCCGCCCCTTCCGCCATTCGGACCACCGCGTGGACTTCCTTTTTTAGGGAGTATCATGAACGGGCTCAGCGGCGCTAGGCCAGGAGGAGGCTTCGATCTGTTGGCTCGGCCTCCGATGGGCTCGTTCCCCGGTGTCAAACCGTTCCAGGACTCGGTCATATCGCACCACCATCACCATCACCATCACcatccacctggcaagatgaaggaccgctacacttgcaaatattgcggcaaggtctttccgagatcggcgaacctgacgaggcacctgaggacccacactggcgaacaaccgtacaagtgcaaatattgcgacaggtcgttcagcatatccagcaatcttcagcgtcacgttaggaacattcacgacaaacagaggcccttcaagtgtccgctttgcgagagatgcttcggtcaacagacgaaccttgaccggcacttgaagaaacacgaggCTGATGACGGGAGCGGCGTCGTTTCCGTTGCGGACTCACCCGGAAGCAGCAACGAAAACGAACGGGAAGATGCCTACTTCGATGAGATCAGGTCCTTCATGGGCAAGGTGACGTACGGCGGCGATGGCGGGTACGGATTGGACCGTCATCATCGTCCCACCTACTGCACCATGCCCAGCAGATTGCGACTCGGTGAAGAATCCGACGTCAGCGAGGAGGACGTCTCGCCCCTTGAGGAAACCGACGTTCTCTCCCCACTCGAGCCCAAGGAATCACCTCCCCCGCCTCAGTACGAGCTCGAATTTAGGGACAAGCCCGAATTGCTCAACAACAATACCGCCTCGCCGGTCATCGAGATCTCGACATAG
Protein Sequence
MKLFVTVVVLVVEEAEERAEVSSMETSERVIIGQTNLSLELSAHVRAHLVADKAKKKKGSPLRDEDQFFRCAPVERARRKIGKTCGGCEDWAGKISEEERRNIPETLKSVAAELTHHCRKVRIAGSGVRGWLDASHEAGNWLKYVRSTTNPHAVNMRHVLINGQMFYETMRDMSASEELLLGLREPLQLQDMLGENTTEDRSDRETASQHSGTVDEDREEEGEGEIRCTVCDRPFQDIELLDNHLVTCHRYPSDQHRCESCPSGYAWRPLLVRHRAIKHGDLRKYSCENCPKSQPPQVFTDPSNLQRHIRDRHVGARSHACTECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHKRMHSDCRMQIKCVKCGQSFSTSTSLTKHKRFCDSTTPASGAMPQLPPSGPSPYLVFPRPPVSLPGCMPFYPPYPGIFPNGPNFLNGPLLFPPKVQQQQQHPTEQADKRSESPKKERFTPPRLLPQHNKVSPSAAEEATSTFRPSPARPPIQSTPDTDDDTSRRRDTGQRQEKRMKMTESAGLSSNETSTDQPLDLRVQTKRDDEAGPPTSQANDARSRTPSPTPAPMEESATEASKHSEEEDTTMDVSEVKEESSLQLRTTATQEQPPPNTPPYMAYPRPIHPQTQAMFLEAMYRNTGGTGFPGFPGGPQAPGCSPESRLLPPLPPFGPPRGLPFLGSIMNGLSGARPGGGFDLLARPPMGSFPGVKPFQDSVISHHHHHHHHHPPGKMKDRYTCKYCGKVFPRSANLTRHLRTHTGEQPYKCKYCDRSFSISSNLQRHVRNIHDKQRPFKCPLCERCFGQQTNLDRHLKKHEADDGSGVVSVADSPGSSNENEREDAYFDEIRSFMGKVTYGGDGGYGLDRHHRPTYCTMPSRLRLGEESDVSEEDVSPLEETDVLSPLEPKESPPPPQYELEFRDKPELLNNNTASPVIEIST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00266682;
90% Identity
iTF_01379477;
80% Identity
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