Basic Information

Insect: Clanis bilineata
Gene Symbol: ZEB2
Assembly: GCA_036417725.1
Location: CM071138.1:4505103-4527046[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 1.8 1.2e+02 3.9 1.3 1 23 308 331 308 331 0.93

2 18 0.035 2.4 9.3 0.2 2 23 339 360 338 360 0.96

3 18 0.22 15 6.8 2.4 3 23 397 418 395 418 0.93

4 18 0.00075 0.051 14.6 0.2 2 23 421 443 420 443 0.96

5 18 2.4e-05 0.0017 19.3 1.9 1 23 449 471 449 471 0.97

6 18 0.042 2.9 9.1 3.1 1 22 510 531 510 533 0.89

7 18 0.0009 0.061 14.3 0.7 2 23 540 562 539 562 0.97

8 18 2.4e-05 0.0017 19.3 2.3 1 23 570 592 570 592 0.97

9 18 0.00011 0.0076 17.2 0.1 1 23 598 621 598 621 0.97

10 18 0.0012 0.082 13.9 2.8 1 23 722 744 722 744 0.98

11 18 0.4 27 6.0 0.6 2 23 775 797 774 797 0.93

12 18 0.00025 0.017 16.1 3.4 1 23 800 823 800 823 0.96

13 18 0.021 1.4 10.1 0.4 1 19 828 846 828 847 0.96

14 18 0.17 12 7.2 0.3 3 22 862 881 861 885 0.91

15 18 0.0057 0.39 11.8 0.2 2 23 899 921 898 921 0.95

16 18 0.00045 0.031 15.3 0.7 1 23 927 950 927 950 0.97

17 18 9.4e-06 0.00064 20.6 2.2 2 23 960 981 959 981 0.97

18 18 1.8e-05 0.0012 19.7 0.3 1 23 987 1010 987 1010 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	1.8	1.2e+02	3.9	1.3	1	23	308	331	308	331	0.93
2	18	0.035	2.4	9.3	0.2	2	23	339	360	338	360	0.96
3	18	0.22	15	6.8	2.4	3	23	397	418	395	418	0.93
4	18	0.00075	0.051	14.6	0.2	2	23	421	443	420	443	0.96
5	18	2.4e-05	0.0017	19.3	1.9	1	23	449	471	449	471	0.97
6	18	0.042	2.9	9.1	3.1	1	22	510	531	510	533	0.89
7	18	0.0009	0.061	14.3	0.7	2	23	540	562	539	562	0.97
8	18	2.4e-05	0.0017	19.3	2.3	1	23	570	592	570	592	0.97
9	18	0.00011	0.0076	17.2	0.1	1	23	598	621	598	621	0.97
10	18	0.0012	0.082	13.9	2.8	1	23	722	744	722	744	0.98
11	18	0.4	27	6.0	0.6	2	23	775	797	774	797	0.93
12	18	0.00025	0.017	16.1	3.4	1	23	800	823	800	823	0.96
13	18	0.021	1.4	10.1	0.4	1	19	828	846	828	847	0.96
14	18	0.17	12	7.2	0.3	3	22	862	881	861	885	0.91
15	18	0.0057	0.39	11.8	0.2	2	23	899	921	898	921	0.95
16	18	0.00045	0.031	15.3	0.7	1	23	927	950	927	950	0.97
17	18	9.4e-06	0.00064	20.6	2.2	2	23	960	981	959	981	0.97
18	18	1.8e-05	0.0012	19.7	0.3	1	23	987	1010	987	1010	0.96

Sequence Information

Coding Sequence: ATGGATCCACAAAGAAATATATGTTCAACATGCTTGAGCAACGATCGAAGATTGTCACCTTTGTCGAAAATATCTTCAATAATTAATGAAATCAATTTGCAAGAGTTGAACAAGCCTGGTTTTGTGTGCTGGGAATGCTATGCAATCATAATGAAgttttacaagtttaaaaaacgttGTAAACAAGCTGAGACTGCTCTAAATAGTCATAGAAAGAAACTTAAACCCCTTTCAACTCTCAGACACACAAAGGCACTTTATGATCTTAACTATAATGATCCACTTACAAACTCGGATATAGACAAAATGGAAATAAAGACTGAACCTGAAGAGATGGATTTCAAAAATGAAACTAATATAACTATATATGAAGATTGTATACATGCTTATAATTCTGGCATAGACAAAGTAGAAACTAATTTAGATAGACCATATAAGGATAGAAATGAAAATGTGTCTAAAATAgtcaaaaatgtaaatgtagaaGAATGTTCAGATATTGACAATATGAAGCATCATGTAACAATATATGCAGATTATATCCATGCAAATAATTCTTGCATAGATCAAGTAGAAAATAATGTAGACAAAGAAGCAACTAAGGAAAGAAATATAAAGTCTAATATAGACAACATTAAAAATGCAGAAGTAATTCCAGGAATAGACAATATAGATGATAAAACAATCACAGACATTTCAGATGTAGAGATTATAGAAAAAGACACTGATATTGGCATAATAGAAGATTCAGATACTGATACAGAAATtaaaagaaagataaataaaactgtaaatgtgaaactaaataaaataactaaagATAAAGTTTTGGAAAAGTTTGATTATATAGTTTTTACAGAGGAAGAAGTTATCAAAAACAGGGAGGAGAAACAAAATCGACCGAATTATAAAAAGATTCCGTTTAAATGTGACTCCTGTGTGCTTGGTTTTACAAAGAAGATGTTTTATATACAGCATGTTGTAAAGAAACATGATGAgagcaTAGGAAACTCTGTATGTCCAGTATGCGACGTGCGATTTCCTAACACACTAGCGATGGAGCGGCATAAAACCAAGCATTACACATGCTACCGATGCAAGTTGTGCAAGTACGATACTGTGGAGTTGTGGTCGGCCATGAACCACTGTCGAATAAAGCATGCGCGAGATACTGCCGACAGTATACACTGTGCTCAGTGCCAGCATGTGTGCAGATCACCCGAAGAACTATCTGAACATGTAAAGTTGGAGCATATTGTGTCGTGTAGTGAGTGTGGAGTCACTTTTAAAGGAGTAGCGTCACTCAAAAGTCACAAACGTCGTGTACACGCAGTGAAAAGAAATTTTCAGTGTGATATATGCAAAAAGACATTCACGAAGAAGTCTCGACTGGAATCCCACGTGGTCAGACATAACGACATCATAGCTAAGAAACTGGCGTACTGTGCCATATGTGACGTGCAGTAtaagaatattaatatatacaGAAGTCATTTAAGAACTAGCACCAACCATAATGAAAGATTatTCCCATGCTCGGTGTGTAACAAAAACTTTGCGTCGAAATTTTATAGAAAACAACATTACGATTTCTATCATCTGCAAAAGTCTAAGAATAAGTGCGATATATGTAATAAGATATTCATATCTGCCTGGCGTCTAAGAGACCACAAACAAACGAAACACGAGACCAACCGCCCGCGAGACCATCCTTGCACCGTATGTGGGAAAAAGTTTTTTACTGCTTCGATGCTGCGCTCGCACAAGTTGACCCACTCGGACCAGCGCTCGTACATGTGCGAAGACTGCGGGGACACGTTCAGACAAGCGCCAGCGCTGTACACGCACATGCGACTTGTGCATAAGGGGaatatcACATTAAATACATTGTCCAACTTAACAATATGttcaacaaataaaataatagacgtAATTTATGAAGAAAAACCCGATATAGATACTTATAATGAAGAAGAAATACCCATAGACGCTTATAATGGCCAAGAAATAGCTATAGACACTTACAATGGAGAACAAATAGCTATAGGCACTTATAATGGAGAAGAAATAGCTATAGAAACTTATAATGCAGAAGAAAAAATAGACATAGAGATAAAACACGAAGAAATTGAAACTGATAAAATTTACGAATTATCCGGCACGCACAAGTGTCACATATGTTCATCAGGCTTCAAGACCATACAGTCCCTCATAGTGCATATGAAAATACACACAAAGGCGTTGCAGTGTGGTGTGTGTGCATACAATTGTTATTCTATATGCATCATGAAGGTTCATTTGAAAGCTCATAGGAGCGAGGTGCAGTGCCTGGCCTGTGATTTGAGACTAAAAAACACCTCTGAGTTCCGAACGCATTATAAAGAGATGCATAATTCGTTTATATGCGACCTCTGTGGAAAGCGATGTGGAGTCAAAAGCATGTTAGAGAAACACATGAGGCACACCCACAATTTCGCCACATTCAGATGCGAGCACTGCTCCGTTAAGTTCGCGAGTGCCAGGAGACTGCGCGCGCACGTGTGGTTCCGCCACGTGGCGCCGAAGAGCGCGGAGCTCGCGTACTGCGTGTCGTGCGACTTGCAGTTCGAAACCGCGGGGCTGTACCGCAGGCATCTCAACAGCAGCGTCAAGCATGCCGACGAGAGGGCCGGCAGAGTAAAAAAGGAGCCAGTAAAGTGTCCGGAATGTCCCAATGTATACGCTCGGAGACAGTACATGAGGAATCATTACAATTATGTGCATCTAAAGAAAACCAAATATTACTGCTCTGAGTGTGATCGGtattTCCTGAATAACACGAATTTGTTGGCCCATATAAGGTATGATCACGAAGGGGCTGAGAGAGAGAAGAACAAAATGTGCAACCTTTGTGGAAGGAAGTTCAGTACTACAAGAACACTGGTCCAGCACATGAGAACTCATTCGGGAGAGCGTCCGTACGAGTGTCCACACTGCGATAAAGGTTTCGCTCAACCATATGCGATGAAGCTACATGTCAAGAATGTGCATGGGAAGCGGAAGAACAGATAA
Protein Sequence: MDPQRNICSTCLSNDRRLSPLSKISSIINEINLQELNKPGFVCWECYAIIMKFYKFKKRCKQAETALNSHRKKLKPLSTLRHTKALYDLNYNDPLTNSDIDKMEIKTEPEEMDFKNETNITIYEDCIHAYNSGIDKVETNLDRPYKDRNENVSKIVKNVNVEECSDIDNMKHHVTIYADYIHANNSCIDQVENNVDKEATKERNIKSNIDNIKNAEVIPGIDNIDDKTITDISDVEIIEKDTDIGIIEDSDTDTEIKRKINKTVNVKLNKITKDKVLEKFDYIVFTEEEVIKNREEKQNRPNYKKIPFKCDSCVLGFTKKMFYIQHVVKKHDESIGNSVCPVCDVRFPNTLAMERHKTKHYTCYRCKLCKYDTVELWSAMNHCRIKHARDTADSIHCAQCQHVCRSPEELSEHVKLEHIVSCSECGVTFKGVASLKSHKRRVHAVKRNFQCDICKKTFTKKSRLESHVVRHNDIIAKKLAYCAICDVQYKNINIYRSHLRTSTNHNERLFPCSVCNKNFASKFYRKQHYDFYHLQKSKNKCDICNKIFISAWRLRDHKQTKHETNRPRDHPCTVCGKKFFTASMLRSHKLTHSDQRSYMCEDCGDTFRQAPALYTHMRLVHKGNITLNTLSNLTICSTNKIIDVIYEEKPDIDTYNEEEIPIDAYNGQEIAIDTYNGEQIAIGTYNGEEIAIETYNAEEKIDIEIKHEEIETDKIYELSGTHKCHICSSGFKTIQSLIVHMKIHTKALQCGVCAYNCYSICIMKVHLKAHRSEVQCLACDLRLKNTSEFRTHYKEMHNSFICDLCGKRCGVKSMLEKHMRHTHNFATFRCEHCSVKFASARRLRAHVWFRHVAPKSAELAYCVSCDLQFETAGLYRRHLNSSVKHADERAGRVKKEPVKCPECPNVYARRQYMRNHYNYVHLKKTKYYCSECDRYFLNNTNLLAHIRYDHEGAEREKNKMCNLCGRKFSTTRTLVQHMRTHSGERPYECPHCDKGFAQPYAMKLHVKNVHGKRKNR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -