Basic Information

Insect: Cimex lectularius
Gene Symbol: -
Assembly: GCA_000648675.3
Location: NW:551653-558642[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 0.66 41 4.3 0.0 1 23 155 178 155 178 0.80

2 19 0.00025 0.016 15.1 3.4 1 23 182 204 182 204 0.95

3 19 6 3.7e+02 1.3 0.1 2 14 244 256 243 257 0.89

4 19 0.88 55 3.9 0.5 1 9 265 273 265 279 0.86

5 19 0.08 5 7.2 0.9 2 21 424 442 423 443 0.92

6 19 0.089 5.5 7.0 0.1 3 20 513 530 511 535 0.90

7 19 0.31 19 5.3 0.0 2 21 612 631 611 632 0.94

8 19 0.13 8 6.5 0.7 2 22 636 656 635 659 0.89

9 19 0.059 3.7 7.6 4.8 1 23 680 702 680 702 0.97

10 19 0.0096 0.59 10.1 0.5 3 23 711 732 710 732 0.93

11 19 0.024 1.5 8.8 3.8 1 23 737 759 737 759 0.96

12 19 0.0015 0.094 12.6 1.3 1 23 762 785 762 785 0.94

13 19 0.00079 0.049 13.5 0.1 1 23 789 811 789 811 0.98

14 19 0.00033 0.02 14.7 0.3 2 23 818 839 817 839 0.93

15 19 7e-07 4.4e-05 23.1 0.2 1 23 845 867 845 867 0.98

16 19 0.015 0.93 9.5 1.0 1 23 872 894 872 894 0.98

17 19 7.5e-07 4.7e-05 23.0 0.7 1 23 898 920 898 920 0.98

18 19 3.7e-07 2.3e-05 24.0 0.4 1 23 926 948 926 948 0.98

19 19 0.24 15 5.7 4.4 1 23 954 977 954 977 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	0.66	41	4.3	0.0	1	23	155	178	155	178	0.80
2	19	0.00025	0.016	15.1	3.4	1	23	182	204	182	204	0.95
3	19	6	3.7e+02	1.3	0.1	2	14	244	256	243	257	0.89
4	19	0.88	55	3.9	0.5	1	9	265	273	265	279	0.86
5	19	0.08	5	7.2	0.9	2	21	424	442	423	443	0.92
6	19	0.089	5.5	7.0	0.1	3	20	513	530	511	535	0.90
7	19	0.31	19	5.3	0.0	2	21	612	631	611	632	0.94
8	19	0.13	8	6.5	0.7	2	22	636	656	635	659	0.89
9	19	0.059	3.7	7.6	4.8	1	23	680	702	680	702	0.97
10	19	0.0096	0.59	10.1	0.5	3	23	711	732	710	732	0.93
11	19	0.024	1.5	8.8	3.8	1	23	737	759	737	759	0.96
12	19	0.0015	0.094	12.6	1.3	1	23	762	785	762	785	0.94
13	19	0.00079	0.049	13.5	0.1	1	23	789	811	789	811	0.98
14	19	0.00033	0.02	14.7	0.3	2	23	818	839	817	839	0.93
15	19	7e-07	4.4e-05	23.1	0.2	1	23	845	867	845	867	0.98
16	19	0.015	0.93	9.5	1.0	1	23	872	894	872	894	0.98
17	19	7.5e-07	4.7e-05	23.0	0.7	1	23	898	920	898	920	0.98
18	19	3.7e-07	2.3e-05	24.0	0.4	1	23	926	948	926	948	0.98
19	19	0.24	15	5.7	4.4	1	23	954	977	954	977	0.96

Sequence Information

Coding Sequence: ATGATGAGGCAGGACACAGATTGGACAACACTGAACAAAATGGAAAAGGAATATTTCTGTTTTGTCTGTGGTGCCAAATCAAGTGATCGGGGTTTGCCGCTTCTACTCTCCGAGACGACTTATTCGCATATTTGCCTCGGTCAGAAGCTGCAAGAGATCTTAGGTGACAAGTTGATTGTCCTGATAAAGCCCAGAGACTCGGTCTGTTGGAACTGTGCTGAAGTCATTAACTGGGTGGACAAATACGAAATCCGAATCGACATTGCCAAAGACAAccttacaaatcaaattattaaaaagtacaagAAGATTGAAATGTGCCTTAGGAGTGAAAGTTCCGATTACTTTGAGAAAgATTTTCCGGCGCCTTCAAATGATGAGgtAATGCACGAGaatgaaacaaacaaatcaaaaaatcatCACTTGTCTCAAGTGGATTCTAAAGGATTAAAGAAAAAGACATTTCCTTGTTCAGTGTGTCATAAATTGTATGCTACCGCTGCAGCTGCAGGTGCTCATGCCGCCAAAGTTCACCGTCAAAACTTTACTTGCGAATATTGTGACAAAATATTCTCATCggaaaagaagtacaaaaaCCATCTATATTTTCATGATAACGTAACTAACGTCGAAAATTCGAAACTTTTAAGCTGTGTTTCGTGCGGGTTCAAAACTACAAACACAGAAGTTTATTGTAGGCACGTTTGCAACTCGGCAATAATGTCACTTACTTGTATGACGTGCAAAAGAAGATATGTCGATTCTAGTATGTCAAAAGGACAGACATTGAAGTACCAGTGCAAGGATTGTAAAAAGCAAACTGACGAGCCAGAAGAAATcccaaagaaaattgaaaaagtacaaAGTATAAATGTTCCAGAGAGTTCAGTGATAACGGAAAAAACAGAATTTCACTCTGAAAtggcagaattttttcattcagtTGAATCTAGTGAATCTCCTCAACCACCCGCTGACGATGTCATATTGGAAGAAGAGCCAGTGACAATAATTCAGAATGGAGTTACCAATGAAGAATTGAGTGTGGAAAGCGAAAAACAAACTGAAGAAATAACTGTTATTAATAGGGAATGTGAAATCgaagaggaagaggaagaaaaaaatataatcactaCTTTATTGGAGTCAGATATAACAATACACGAAGACACAGGAGATGATGGTAATTTAACAGACAACATGACAGTGACGGAAGAGACAGAAGTGATGAGTAAGAATTCAGATTTTATCATCAACCAATCTTATTTAAAATGCACCAATTGTGGTGAAGAATTTGAATTGTCTCAATTAGCTAGTCATCAGTGCTTTGTACGGGGAGATGTCGTTGAATTTGCAGAAGTTGAAAGGCAGGTTGAACATCAGTACTATAccgttcctttttttaaacctgacGAAGAAACCAACACCACAATGTATGAGACCCAAAAACCAGCACAACGTAGACGACGGATACCAAAAATACCAGCTCAAGAAAATTCTTACATCAACCTAAATGACAACATGActaaaatgaattgtaaaacaTGTGGAGCTGAATTCAAAACGATTGGTTTAATGAGGCAGCACTGGGACTTAACGGGTCATTTACGAGAAGTTTCAACGACGACAATagaattgaacaaaattaaagataagacgagaaaaactgaaaagacCTTTAAAGTtgtcaaacaaaattttcatataaGAGCCAACGTTCCTGGACAAAACGATGATGAGATTAGAAAAAACGAAGAGGTCCAAATGAACTGTATTGTCAAGTTCAAAAATGATATGAGTGTAGAAGATTTTATTGGAATGAAAGGAGGGAAAGAATGTGAAACTTGTGGCATACTTTTTGGAAGTGAAGACGTCTTAAAAGAGCACCAACAGAACAATTGCTTGACCTGTGTTACATGTAACGTGACATTCTTagataataaacttttaagaaaacattATCAATATACAGGTCATGCGAACAGAATTCCTGTAAAGGGTGACGACCAAGTCACTTTAAAAACAGAACATGAATCTTTCAGTTGTCATGTCTGTTTCAAAACTTTCTACTCAAGATTCATATTGGGAAAACATCTGCAGAAGCATTACAAAGGGACTTCAAAAGGTGCTTGTCGTTATTGTCAAATGGAGTTTGAAGATAAATCGCATATTCAACAGCATGTCTTAGAGGTTCACGGTGCCCAATTGTATAAATGCCAACACTGTGATAGGACGTTTTTAAGTGAATCTGTTCGGAATCGCCATCAAATCAAGCACAAAATGTATACTTGCAAAacgtgtaaaattaaatttcctacTCAACGCCTTTTCATGTCTCATTTAGATCAGGCGCATAGAAATTCGTTCTCTTGCGTCATTTGTGGTAAAGTTATACAAGATTTACAAGCACTGAAGAGGcatgaaaaaatgcatttttacgGAAAGAATCTTCAATGCGACTTGTGTGGGAAAACATTCAGGAGCAAAGCAATTTTGAAAGCCCATTCGACCGTTCACCAAAATGAACCTCACTTCAAGTGTAAATATTGTGGCCTCGGATTTAAGACTGCTGAAAATCTTGAAGAGCACCAAATCATTCATATCAAGAAGGAGTACACATGTCCTAAATGTTCTGTGATCTGCCCGTCGAGAATATTTTTTTGGGTGCATATGAAATTGCACGACACAGCATATATGTGTAGTGTCTGTGGGCGGACGTTTAGAGACACATCGTTACTTGCAGTTCATAGACGCAAACACTGGCGAGTGCGACCTTACCAATGTCCCCATTGCCCTAGGGTATTTTCAGTTCCGGCCACCCTCAGGCGACATTTGACCGTACATACTAGAGCTTTTCCACACCGGTGTGTCCTGTGTAAAAAGGGTTTCCTGACAAGATACGCATTCCATAAACACCTCGATACCGTCCACTCTGTTAGGCAATCTCAGCCTAGGAGGCAGGAAAAGAAGATACCTTCGCTGCCGTTGAACGCGACTGACGAAGATCTTTTCCAGGCCGCCGATACGTTAATTTCCGATGATACAATCATGTTTAATGATTATACTCAAAAAGATATGAAAATTGAACAAGTATCATCAAATGATCTTACAACAAATGAAGTTGTTGTTGAAACGACAGAATTGTTTGATGTTCTCCCATAA
Protein Sequence: MMRQDTDWTTLNKMEKEYFCFVCGAKSSDRGLPLLLSETTYSHICLGQKLQEILGDKLIVLIKPRDSVCWNCAEVINWVDKYEIRIDIAKDNLTNQIIKKYKKIEMCLRSESSDYFEKDFPAPSNDEVMHENETNKSKNHHLSQVDSKGLKKKTFPCSVCHKLYATAAAAGAHAAKVHRQNFTCEYCDKIFSSEKKYKNHLYFHDNVTNVENSKLLSCVSCGFKTTNTEVYCRHVCNSAIMSLTCMTCKRRYVDSSMSKGQTLKYQCKDCKKQTDEPEEIPKKIEKVQSINVPESSVITEKTEFHSEMAEFFHSVESSESPQPPADDVILEEEPVTIIQNGVTNEELSVESEKQTEEITVINRECEIEEEEEEKNIITTLLESDITIHEDTGDDGNLTDNMTVTEETEVMSKNSDFIINQSYLKCTNCGEEFELSQLASHQCFVRGDVVEFAEVERQVEHQYYTVPFFKPDEETNTTMYETQKPAQRRRRIPKIPAQENSYINLNDNMTKMNCKTCGAEFKTIGLMRQHWDLTGHLREVSTTTIELNKIKDKTRKTEKTFKVVKQNFHIRANVPGQNDDEIRKNEEVQMNCIVKFKNDMSVEDFIGMKGGKECETCGILFGSEDVLKEHQQNNCLTCVTCNVTFLDNKLLRKHYQYTGHANRIPVKGDDQVTLKTEHESFSCHVCFKTFYSRFILGKHLQKHYKGTSKGACRYCQMEFEDKSHIQQHVLEVHGAQLYKCQHCDRTFLSESVRNRHQIKHKMYTCKTCKIKFPTQRLFMSHLDQAHRNSFSCVICGKVIQDLQALKRHEKMHFYGKNLQCDLCGKTFRSKAILKAHSTVHQNEPHFKCKYCGLGFKTAENLEEHQIIHIKKEYTCPKCSVICPSRIFFWVHMKLHDTAYMCSVCGRTFRDTSLLAVHRRKHWRVRPYQCPHCPRVFSVPATLRRHLTVHTRAFPHRCVLCKKGFLTRYAFHKHLDTVHSVRQSQPRRQEKKIPSLPLNATDEDLFQAADTLISDDTIMFNDYTQKDMKIEQVSSNDLTTNEVVVETTELFDVLP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -