Basic Information

Insect: Cimex lectularius
Gene Symbol: -
Assembly: GCA_000648675.3
Location: NW:255846-267070[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.00033 0.02 14.7 4.1 1 23 249 271 249 271 0.97

2 11 1e-05 0.00063 19.5 1.5 1 23 277 299 277 299 0.98

3 11 7.9e-05 0.0049 16.6 2.7 1 23 305 328 305 328 0.96

4 11 0.04 2.5 8.1 3.4 1 21 334 354 334 356 0.95

5 11 0.0001 0.0063 16.3 1.9 1 23 362 384 362 384 0.99

6 11 0.00013 0.008 16.0 0.8 1 23 390 412 390 412 0.98

7 11 0.00037 0.023 14.5 0.8 1 23 420 443 420 443 0.97

8 11 0.00014 0.0088 15.8 2.1 2 23 450 471 449 471 0.96

9 11 0.00024 0.015 15.1 0.3 2 23 478 499 477 499 0.97

10 11 0.00081 0.05 13.5 5.1 1 23 505 528 505 528 0.96

11 11 3.3e-07 2e-05 24.1 1.8 1 23 542 564 542 564 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.00033	0.02	14.7	4.1	1	23	249	271	249	271	0.97
2	11	1e-05	0.00063	19.5	1.5	1	23	277	299	277	299	0.98
3	11	7.9e-05	0.0049	16.6	2.7	1	23	305	328	305	328	0.96
4	11	0.04	2.5	8.1	3.4	1	21	334	354	334	356	0.95
5	11	0.0001	0.0063	16.3	1.9	1	23	362	384	362	384	0.99
6	11	0.00013	0.008	16.0	0.8	1	23	390	412	390	412	0.98
7	11	0.00037	0.023	14.5	0.8	1	23	420	443	420	443	0.97
8	11	0.00014	0.0088	15.8	2.1	2	23	450	471	449	471	0.96
9	11	0.00024	0.015	15.1	0.3	2	23	478	499	477	499	0.97
10	11	0.00081	0.05	13.5	5.1	1	23	505	528	505	528	0.96
11	11	3.3e-07	2e-05	24.1	1.8	1	23	542	564	542	564	0.96

Sequence Information

Coding Sequence: ATGAGTGCAAAAAAAGTAGCAGTGAGGCAAGGGCAAACTGTTCGGGTAGTCAAGATAGACGGTGCTACTGTCCAAGCAGTTCAAGCAAATGCAGCCAGTGGAGAAACGATAACTGATATACAAAACTATCTTGAAACGTTCAATAAAGAAATCGGTTCAACCGGGGCCAATGCTGAATCTGCAACAACTCAACAGCAACAACAGCCAGCGGCTGTCCAAGAAGTGGCGCAAGAAGTAAAGTTTGAAACAGTACCTAGTGAAAATGCGAGTGGAGAAAGTGAAACAGGAGCTTATTATGTAGATCAAGCCACCGGTCAGTACTACTATGAATCGAGGGGAGAAGATGGCCAAAGAGTTATGACTGTAGTACAAGGTATTCCTGAAGCAGCTGGTGGTGAAGAACAGTTTGTTTCAATTGCTCAGAATTCTGAAGAAACCGAACAGCAACCAACAGAAGATGTTCAAGTTGTTGATGAAAATGGGCAAATGGTACTTGGTAGTGGAGATTCATTTCAGACAGTGACAATTGTTCCTTCAGAAACTAGTTCGGGGGAAGTCAGTTATGTTCTTATTGTACAACAACCAGAAGATAAGGAAAAGGAAGAAGATCAAGATCTTACCGTCTATGATTTTGACGATCAAGAGGAACCAAACCCACTTAGCGGACCTGAGTCTGCTGATGAAGAggacaaatcaaaaataatcaaGGTCATTCCTAAAAAATCTCAGACCGTCACACAAGTTCACATgtgtaattattgcaattacaCTAGTCCGAAAAGATACCTTCTGTCGAGGCATATGAAATCACATTCTGAAGAACGACCACACAAATGTAGTGTCTGTGAGCGTGGTTTTAAGACATTAGCCTCATTGCAAAACCATGTGAACACCCACACTGGAACGAAGCCCCATAGGTGTAAATACTGTCAAAGTGCGTTCACCACATCGGGAGAGCTTGTTCGACACGTCCGTTACAAGCACACACACGAAAAGCCCCATAAATGCACGATTTGTGACTATGCCAGTGTCGAACTCAGCAAAATGAGAAATCATATGAGATGTCACACAGGAGAAAGGCCTTATCAGTGTCCACATTGCACATACGCCAGTCCAGATACTTTCAAGTTAAAAAGACATTTGCGAATTCACACTGGTGAAAAACCTTATGAATGTGATATTTGTTACTCCAGGTTTACTCAATCAAACAGCCTTAAGGCACATAAACTTATTCACAGtgCTGGTGACAAACCAGTTTACCAGTGCGAACTCTGCCCAGCGACTTGTGGCAGAAAGACTGACCTCAGGATCCATGTGCAAAAGCTACATACTTCTGATAAACCGCTTAAATGTAAGAGATGTGGGAAACAATTCCCTGACAGATATAGCTATAAGGTCCACAACAAATCACACGAAGGTGAAAAATGTTGGAAATGTGATCTCTGTCCGTATGCATCAGTATCTCAGAGACATTTGGAGTCTCACATGCTTATTCATACGGATGAAAAACCATTCCAGTGTAAATGTTGTGATCaggcATTTAGACAAAAACAGCTTCTTAAAAGGCACCAGAATTTATACCACAACCCTAACTATGTACCTCCGACGCCTCGGGAAAAGACACATGAATGCCCAGAATGTCAACGTGCCTTCCGacATAAAGGTAACTTAATAAGACACATGTCTGCTCATGATCCTGACTCTGCAGCACACGAGATTGCTTTGGCTTTGAAGTTGGGCcgtcagaaaaaaatacaaataatcgACGGCCAACAAGTTGAAGTGATTCCAGATGCAGAAGACGaggatgaagaagaaattgaagaaagtGGTGTCATGGACAGCTCGGTCGTGGCTGTAGAGGGTAATGACGGTCAACAGTACGTCGTACTCGAGGTTATTCAACTTAATgACGGTGAAGATCAGCATGTTATGTTGAGTGGAAACCATACTATTCAACAAGCAGTGGCTGCAGCACTCCAAACAAATGAAACCACAGGAGACACTGAAGTAATAATTCctgataatttcaaaaatgatgGAACAAAAAGACAAGATGTCCAACAAGACATGGAAAATTGTTTTGGGTTCGAtgatgaagaggaagaaaaggTCGATTTGGACGATCTGGAAGAAGACAAGAAACTACAGGTCATTCAAAGTAATTTAGACTAG
Protein Sequence: MSAKKVAVRQGQTVRVVKIDGATVQAVQANAASGETITDIQNYLETFNKEIGSTGANAESATTQQQQQPAAVQEVAQEVKFETVPSENASGESETGAYYVDQATGQYYYESRGEDGQRVMTVVQGIPEAAGGEEQFVSIAQNSEETEQQPTEDVQVVDENGQMVLGSGDSFQTVTIVPSETSSGEVSYVLIVQQPEDKEKEEDQDLTVYDFDDQEEPNPLSGPESADEEDKSKIIKVIPKKSQTVTQVHMCNYCNYTSPKRYLLSRHMKSHSEERPHKCSVCERGFKTLASLQNHVNTHTGTKPHRCKYCQSAFTTSGELVRHVRYKHTHEKPHKCTICDYASVELSKMRNHMRCHTGERPYQCPHCTYASPDTFKLKRHLRIHTGEKPYECDICYSRFTQSNSLKAHKLIHSAGDKPVYQCELCPATCGRKTDLRIHVQKLHTSDKPLKCKRCGKQFPDRYSYKVHNKSHEGEKCWKCDLCPYASVSQRHLESHMLIHTDEKPFQCKCCDQAFRQKQLLKRHQNLYHNPNYVPPTPREKTHECPECQRAFRHKGNLIRHMSAHDPDSAAHEIALALKLGRQKKIQIIDGQQVEVIPDAEDEDEEEIEESGVMDSSVVAVEGNDGQQYVVLEVIQLNDGEDQHVMLSGNHTIQQAVAAALQTNETTGDTEVIIPDNFKNDGTKRQDVQQDMENCFGFDDEEEEKVDLDDLEEDKKLQVIQSNLD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -