Basic Information

Insect: Cimex lectularius
Gene Symbol: -
Assembly: GCA_000648675.3
Location: NW:1668579-1681543[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 5.8 3.6e+02 1.3 0.3 3 23 8 28 7 28 0.90

2 15 1.1 70 3.6 1.1 1 23 308 331 308 331 0.91

3 15 0.00012 0.0076 16.0 1.8 2 23 345 367 344 367 0.96

4 15 0.045 2.8 8.0 0.0 2 23 373 395 373 395 0.96

5 15 0.00018 0.011 15.5 4.7 2 23 398 419 397 419 0.96

6 15 1.8e-05 0.0011 18.6 1.1 1 23 425 447 425 447 0.95

7 15 5e-06 0.00031 20.4 1.6 2 23 454 476 453 476 0.93

8 15 0.0053 0.33 10.9 0.4 5 23 489 507 488 507 0.97

9 15 8.6e-05 0.0054 16.5 1.9 2 23 513 535 512 535 0.97

10 15 0.0032 0.2 11.6 0.1 2 23 552 572 551 572 0.96

11 15 1.4 87 3.3 1.6 5 20 582 597 580 600 0.87

12 15 7.9e-06 0.00049 19.8 0.4 1 23 608 630 608 630 0.98

13 15 0.00014 0.0084 15.9 5.4 1 23 636 658 636 658 0.97

14 15 5.1e-07 3.2e-05 23.5 2.1 1 23 664 686 664 686 0.99

15 15 0.00093 0.058 13.3 9.3 1 23 692 714 692 715 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	5.8	3.6e+02	1.3	0.3	3	23	8	28	7	28	0.90
2	15	1.1	70	3.6	1.1	1	23	308	331	308	331	0.91
3	15	0.00012	0.0076	16.0	1.8	2	23	345	367	344	367	0.96
4	15	0.045	2.8	8.0	0.0	2	23	373	395	373	395	0.96
5	15	0.00018	0.011	15.5	4.7	2	23	398	419	397	419	0.96
6	15	1.8e-05	0.0011	18.6	1.1	1	23	425	447	425	447	0.95
7	15	5e-06	0.00031	20.4	1.6	2	23	454	476	453	476	0.93
8	15	0.0053	0.33	10.9	0.4	5	23	489	507	488	507	0.97
9	15	8.6e-05	0.0054	16.5	1.9	2	23	513	535	512	535	0.97
10	15	0.0032	0.2	11.6	0.1	2	23	552	572	551	572	0.96
11	15	1.4	87	3.3	1.6	5	20	582	597	580	600	0.87
12	15	7.9e-06	0.00049	19.8	0.4	1	23	608	630	608	630	0.98
13	15	0.00014	0.0084	15.9	5.4	1	23	636	658	636	658	0.97
14	15	5.1e-07	3.2e-05	23.5	2.1	1	23	664	686	664	686	0.99
15	15	0.00093	0.058	13.3	9.3	1	23	692	714	692	715	0.96

Sequence Information

Coding Sequence: ATGGAGGGGCAACTGGTAGCTTGCCCCGTATGCACCCTGTACCTGAGGGAAGGGATGTCGATGCATGCCCATTTGAACACTCATCCCAAGGATCAAGTGATAGAAGCGCTTGTGAGGCTTTATACCCAAGAACAGCCGTTGAACCTACAGCAATTGGCTTCGAACGTCTCATCGACACCCCTCATCAACCCGTTTCAAGTCGTATCCGAAGAACACATCTTGTTAGGAAGGCAGCAAGTCACAAACATAATCCACGCGCCGTTGATGTCTTACCCTATATATTCCCAACCTCAAGTCCTAGGTTCGAATCACAATGAATTCATAAGTCAGACGGAAATTGGGAGGACGGAAATAATCGGGGTCAATACTCAGACGACTGAACCTGTCGTTACAGCACTTATAAACGTCGACGATAGAGATTATCCAGCAGGTCAACATAGCCAGAATGATGTAGACAAAGTTGAACTGAATGAAGACGATCATGACAAATCTTTCATTGAGATTCAAAACCAAGCTCCTTCGCCAGCTAGTGTTCATTCACTTTTATCCGTTCGGACTGACTTGACAAACCCTGATCAACCAGACCCGGAGCAATGCCCTGAATACATTACATCAGATGGGGATTTTCAAGATGAGGACGCAAGACATAGTGAAGATCTCATGAGTAACAatgAATATGTTGGCGGTGAAAAATCGAAGAAAGGCGAACATAAACAAATACTCGAAGTCGAATTAGATAGGAGCAGTTCAGGACTTAACATACAAGCCGAAGAATGTATGCCACCGAGAGGAGAACTTTCTGGACATGGGAGCCTGGGAGATACCGGACCAGAAAACATTTGGATAAGAGATGAATTACAGAGCCAATTCATAGGTGTTCCAGGACCTTTGTGGGATGAATCCAAGGATACGAAGAAGAAATACATGTGCTTGTACTGCGAACAGGAATTTAATTGTCCAAAAGAAAGACGTGTTCATGTAGCAACCTTGCATTGCAATCAGGACTCAAAGCAAGGGATTAAGAAAACTATTATGTGCACAAAATGTGGACTGCATTTAAGTACTCAAAAGGAATTGAAAGTGCACACTAGAACGgagcataaaaaaatttccaggCAATGTGGTGTTTGTATGCAAGTTTTTCCAACTCAGGAGCTCTTCGTtgaacatataataaaaatacatccaTTGGAATGTAGGACTTGTGGAAAGACCTTTCACAGTAAGTCGAGCCTGCACACTCATGCAAAAATTCATCTGGATCTAAAGCCTCACGCTTGTTCGCTGTGTCCTAAATCGTTCATTTCAAATCAGAAATTGAAGGAGCACATGAATGGACATACCGGTTACGCTCCGATACAATGTAATCTTTGTGATAGAAGATTCAAAAGATATTCCAATCTCAAACAGCACAAGGACAGCGCTCATtttcagattaaaaagaaagtaaaagaatACTTTTGCGAATGCGgtgaaacttttatttcaaaaaagaaattggaTTGGCACAGGGAGACTCACGAAGAAAAACCGAAACAGTGTATGTACTGCAGTGAGAGATATATTCATAATGCGAGTTTAACTCGTCATATAAGAAAAGCTCACAATAGGGAGTATTTACCTGAAGGTGaagatattaaaaagaaaaacgttagTTGTCCCATATGCAGTCAGATTTTTATAGAATCTTCTCTCCGGGCTCATATGAAACAACATGGTAATGTAAAACAATTCGGTTGCATagtttgtgggaaaaaatttttgacaaaatggaatttacatttacataaatgGACACACGCTTCAAGGATATCAAAACCTTTCAAGTGTACGATGTGTAAAGGTGCTTTCATAAGACAAAGTGACTTTCAAGCTCATATAAGAGCACATTACGGCAATAAGCCTTTCACTTGTAATCATTGCGGAATGCAGTTTAATAGAAAACATAATTGGCTCCGACATGAAAAAGAGCACAGTTCAGAAAAAAGATATACTTGTGATGAATGTGGTAAAACATTTCATCGGAATTATTACCTAGTCGATCATTTGCGAATTCATACAGGAATAAAACCATTTTCATgtcatatatgtaataaaacatcATCAACCAAATCCAACCATAACAAGCATATTAAAACCCATCATGCAAGAGAAGCAATAAACACAGAATCTTAA
Protein Sequence: MEGQLVACPVCTLYLREGMSMHAHLNTHPKDQVIEALVRLYTQEQPLNLQQLASNVSSTPLINPFQVVSEEHILLGRQQVTNIIHAPLMSYPIYSQPQVLGSNHNEFISQTEIGRTEIIGVNTQTTEPVVTALINVDDRDYPAGQHSQNDVDKVELNEDDHDKSFIEIQNQAPSPASVHSLLSVRTDLTNPDQPDPEQCPEYITSDGDFQDEDARHSEDLMSNNEYVGGEKSKKGEHKQILEVELDRSSSGLNIQAEECMPPRGELSGHGSLGDTGPENIWIRDELQSQFIGVPGPLWDESKDTKKKYMCLYCEQEFNCPKERRVHVATLHCNQDSKQGIKKTIMCTKCGLHLSTQKELKVHTRTEHKKISRQCGVCMQVFPTQELFVEHIIKIHPLECRTCGKTFHSKSSLHTHAKIHLDLKPHACSLCPKSFISNQKLKEHMNGHTGYAPIQCNLCDRRFKRYSNLKQHKDSAHFQIKKKVKEYFCECGETFISKKKLDWHRETHEEKPKQCMYCSERYIHNASLTRHIRKAHNREYLPEGEDIKKKNVSCPICSQIFIESSLRAHMKQHGNVKQFGCIVCGKKFLTKWNLHLHKWTHASRISKPFKCTMCKGAFIRQSDFQAHIRAHYGNKPFTCNHCGMQFNRKHNWLRHEKEHSSEKRYTCDECGKTFHRNYYLVDHLRIHTGIKPFSCHICNKTSSTKSNHNKHIKTHHAREAINTES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -