Clec002746.1
Basic Information
- Insect
- Cimex lectularius
- Gene Symbol
- lola_8
- Assembly
- GCA_000648675.3
- Location
- NW:3487972-3503063[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 26 0.00049 0.031 14.1 1.4 1 21 22 42 22 43 0.95 2 26 0.00082 0.051 13.5 3.8 1 23 51 74 51 74 0.96 3 26 0.0011 0.07 13.0 0.7 3 21 126 144 124 145 0.93 4 26 0.0044 0.27 11.2 0.8 1 21 153 173 153 174 0.94 5 26 0.0047 0.29 11.1 0.5 3 21 179 197 177 198 0.93 6 26 0.0023 0.14 12.0 1.4 1 21 215 235 215 236 0.96 7 26 1e-05 0.00063 19.5 1.4 1 23 244 267 244 267 0.97 8 26 0.001 0.063 13.2 1.4 1 21 311 331 311 332 0.94 9 26 1.1 66 3.7 1.5 1 23 340 363 340 363 0.85 10 26 0.005 0.31 11.0 2.1 1 21 376 396 376 397 0.94 11 26 0.0017 0.11 12.4 0.3 2 23 406 428 405 428 0.95 12 26 0.00027 0.017 15.0 0.9 1 21 468 488 468 489 0.96 13 26 0.00062 0.038 13.8 0.2 1 20 497 516 497 517 0.96 14 26 6.3 3.9e+02 1.2 3.2 5 22 529 546 526 546 0.92 15 26 0.0011 0.069 13.0 5.2 1 23 552 575 547 575 0.97 16 26 0.00027 0.017 15.0 2.6 1 21 590 610 590 611 0.95 17 26 0.00016 0.0098 15.7 1.1 1 20 619 638 619 639 0.96 18 26 0.0044 0.28 11.1 3.9 1 21 660 680 660 681 0.95 19 26 0.00015 0.0093 15.8 5.3 1 23 689 712 689 712 0.97 20 26 0.11 6.8 6.8 0.6 3 21 728 746 726 747 0.93 21 26 0.048 3 7.9 0.1 3 20 757 774 755 776 0.95 22 26 0.00019 0.012 15.4 3.1 1 21 781 801 781 802 0.96 23 26 0.00087 0.054 13.4 3.1 1 23 810 833 810 833 0.93 24 26 0.0021 0.13 12.2 2.8 2 21 901 920 900 921 0.94 25 26 0.00026 0.016 15.0 2.3 1 19 967 985 967 987 0.96 26 26 0.01 0.63 10.0 4.0 1 23 996 1019 996 1019 0.93
Sequence Information
- Coding Sequence
- ATGGAGTTATTTAGGAACAAGAGCATGAACTGGTCATCTGTAGTTGGAGtaAGCGAGGAAGTGTTTATTTGTAAGGACTGCTCGAAGCCGTACAGGACAAAAGCGGGCCTGCACAACCACAGAAAGTACGAGTGCGGGATCGAACCTCAGTTCAAATGCCCCCATTGCGCCCACAGGTCGAAGCAAAAGGGCAACCTGAAGACCCACATCTCCAACGTCCACCCGGAACAGGCCCTGGGCGACATGTACGACGCCGAAGACCAGTCGAACCGGCCcgtctataaatatttaatctcttcttttgttttacagGGCCATCTATTAAGAAACACGTCTGCGACAGCTGCCACAAGAGTTACAAAGAAAAAGTTGTTCTGCGACAAATGCGACAAGCCGTACACGTCTCGCAGTGGTCTGTACAACCACAAGAAGTACGAGTGCGGTAAGCCTCCGGGCTTCACCTGCCGTCTCTGCGGCCACAAGACGAAGCTCAAAGGAAACTTAAAAGCCCACTTGATCAAGAAGACGATGTTCTGCGACAAATGCGACAAGCCGTATACGTCTCGCGGTGGTCTTTACAACCACAAGAAGTTCGAGTGCGGGAAGGAGCCTTCCTTCAGCTCTGGAACACCCGGTAACTTCTTCAAGTGCCCCGGCTGCTTCAACAGGTACAAATCCAAGTCGGGACTGTACAACCACCTCAAATACGACTGCGGTAAGGAGCCGCAGTTCAGCTGTCCGATCTGCACTTTTAAATCGAAAAGGAAAAGCAACCTGAAAGACCACATACGGAATATACATTCGGCACGAGATCGTTCGGCCCACGGTCAGGaaaaggtttttcaaatttcaatccCCGTCCAACGGGCTCTATCGTCGTGTTGTCTATTATTAACGGACTTCTTTTTTCCCCCCTTTCAAGGTAGGAAGTTCGCCTGCAGTGACTGCGGACGGAGGTACAAGTACAAAGCCGGCCTGTACCAGCACAGAAAGCACGCCTGTGGGAAGATAGCGAGCTTCAGCTGCCCTCATTGCCCCTATAAGGCCCTGATGCGATTTTCTCTCAACTCTCACATTCTTTACAAACACACCACTTGTATAAACTGCGCTGCCCCCGCCAAGAACTACTTCTGCGAACTTTGCGGAAGGGGCTACAAGTACAAGTCTGGACTTTACCAGCACAAGAAGCACGAGTGCGGGAAGGATGTGAAAATCTCCTGCCCACTCTGCCCTTACAGGACGCGGATGAAGTTCAATCTCAACACGCACATCGCCGTCAAGCACGCCGGACACACGGACAGTCTTCTCCGATATTTCGGTATCGAGACGGAATTCCTTCTCATgccgtttttgccattttcaggcACCATCGAATCGCTCATATTGAAAATACCGGAGTACTTCCCTTGCGAAACGTGCGGCAGGATCTACAAATATAGGCGGAGCCTGAAGCTTCATCAGAGGTTCGAGTGCGGCAAAGAGCCCCAGTTTCAGTGCCCTTATTGCCCTTACAAGGCAACTTACAAGGGAAATCTAAAAAGCCATGTCATATGCCGGCACACTAGTAagcTTAGACATCTTTGCACCTGCGGGAGAAAATTTAAATGCTTCGCTATGTTGAAATGGCACCAAAGAAAGGAATGCGGAAGAAAGTTCGACTGTCCCATGTGCACTAAGTCCTACAAAAGACGATCAGAGCTTCATTTCCACATGAAAATGAAACACTTGACATCTATGATCGACCATGAGGCACCGAAATGTGTCAAGTTCGAATGCGACAAATGCCCTAGGAAGTACAAACACAGGGACAGCCTCATCCGACACAAGAAGTTCGAGTGCGGGAAAGAACCGCAGTTCCAATGCCCCGAATGCAATTACAAATCGAAGCACAAAGCCAATCTGAAAGCTCATACCGATCCATTCTACAACGGGCGGAAACGGCTTAACATGTTCTCTTTTGCAGCGCACCTGCCCAGGTTCACATGCGAGAGGTGCAGAAGGAGCTACAAGTACAAATGCAACTTGGTGCAGCACCAGAAGGTTGAGTGTGGCAAGCAGCCGAGGTTCAAATGCCCCCACTGCCCCCACATGACGAAATACAAAAGCTCACTCAAGAAACACCTCGTCACTCAACACACGccgtttttaaacatttGTCTGGTCGAAAGGAAGAAGTTCGGGTGCGACAAGTGCTACCGGAGGTACAAGTACCCCGAGGGTCTTTACAACCACAAGAAGTACGAGTGCGGCAAACCGCCACGGTTCGGCTGCCCGGTTTGCCCTTTCAGGTCGAAACTGAAAGCCAACCTCAAAACCCACATCGCGGaATCTGTTAAACAATTCAAATGCACCGGCTGCCAGAGGAGTTATAAATACAGGGAAAACCTCTACAGGCACAAACGGTTCGAGTGCGGAATTTCGAGGCAGTTCGCTTGCCCGCATTGCCCACACAAATCCAAACAAAAAGTCCACCTGCAAGCTCACATCGCCCTTAAACACGGCCTCCCCGAAGACTCATTATGTTTTTCAACCTTTCCGATGCGACAGTTGCCCCAAGAGTTACAAATACAAGGACAGCTTGAACAGGCACAAGAGGTTGGAGTGCGGCAAGGCACGGCAATTCTCATGTCCGATATGTCCGCACAAGTCTCGGCAGAAAGTACACCTCATGTCCCATATAGCAGGGCCTCCAGCCGCCTCACCTGTGAGTTCTGCTTCAGGACTTACAAGTACAGGAGGAACCTGACCAAACATCAGAAGTTCGAATGCGGGAAGGAGCCACAAATCAAATGTCCCTTACTATCATCCATCACTATCGCCATTGTCCAGGTTTGTCAGTTTATAACCATAATGCCCTTTATTAATATTACGTTGATCATTTCAGATACCGAGCTTGGCTTCACGTGCGACGGTTGTCAGAGGAAGTACAAGCACAAGGGAAGCTTGAAGCGTCACAAAGTCCTCGAGTGTGGAAAGGAAAGGTCGTTTTTCTGCCCTTACTGCACGCACAGGTCGAAACAATTAGCACATCTAAAGACGCACATTGCTTTGAAGCACAATCCGGACCCTCGCTGA
- Protein Sequence
- MELFRNKSMNWSSVVGVSEEVFICKDCSKPYRTKAGLHNHRKYECGIEPQFKCPHCAHRSKQKGNLKTHISNVHPEQALGDMYDAEDQSNRPVYKYLISSFVLQGHLLRNTSATAATRVTKKKLFCDKCDKPYTSRSGLYNHKKYECGKPPGFTCRLCGHKTKLKGNLKAHLIKKTMFCDKCDKPYTSRGGLYNHKKFECGKEPSFSSGTPGNFFKCPGCFNRYKSKSGLYNHLKYDCGKEPQFSCPICTFKSKRKSNLKDHIRNIHSARDRSAHGQEKVFQISIPVQRALSSCCLLLTDFFFPPFQGRKFACSDCGRRYKYKAGLYQHRKHACGKIASFSCPHCPYKALMRFSLNSHILYKHTTCINCAAPAKNYFCELCGRGYKYKSGLYQHKKHECGKDVKISCPLCPYRTRMKFNLNTHIAVKHAGHTDSLLRYFGIETEFLLMPFLPFSGTIESLILKIPEYFPCETCGRIYKYRRSLKLHQRFECGKEPQFQCPYCPYKATYKGNLKSHVICRHTSKLRHLCTCGRKFKCFAMLKWHQRKECGRKFDCPMCTKSYKRRSELHFHMKMKHLTSMIDHEAPKCVKFECDKCPRKYKHRDSLIRHKKFECGKEPQFQCPECNYKSKHKANLKAHTDPFYNGRKRLNMFSFAAHLPRFTCERCRRSYKYKCNLVQHQKVECGKQPRFKCPHCPHMTKYKSSLKKHLVTQHTPFLNICLVERKKFGCDKCYRRYKYPEGLYNHKKYECGKPPRFGCPVCPFRSKLKANLKTHIAESVKQFKCTGCQRSYKYRENLYRHKRFECGISRQFACPHCPHKSKQKVHLQAHIALKHGLPEDSLCFSTFPMRQLPQELQIQGQLEQAQEVGVRQGTAILMSDMSAQVSAESTPHVPYSRASSRLTCEFCFRTYKYRRNLTKHQKFECGKEPQIKCPLLSSITIAIVQVCQFITIMPFINITLIISDTELGFTCDGCQRKYKHKGSLKRHKVLECGKERSFFCPYCTHRSKQLAHLKTHIALKHNPDPR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -