Basic Information

Insect: Cimex lectularius
Gene Symbol: -
Assembly: GCA_000648675.3
Location: NW:280678-285754[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 32 0.0061 0.38 10.7 1.2 1 23 26 48 26 48 0.98

2 32 0.0051 0.32 10.9 1.4 3 23 77 97 75 97 0.96

3 32 0.00017 0.01 15.6 2.2 2 23 104 125 103 125 0.97

4 32 0.00024 0.015 15.1 5.7 1 23 131 153 131 153 0.98

5 32 1.4e-05 0.00087 19.0 2.0 1 23 159 181 159 181 0.98

6 32 1.3 82 3.4 6.8 1 23 187 209 187 209 0.98

7 32 0.00015 0.0091 15.8 1.5 1 23 215 237 215 237 0.99

8 32 0.041 2.5 8.1 7.4 1 23 243 265 243 265 0.96

9 32 3.8e-05 0.0024 17.6 3.6 1 23 271 293 271 293 0.98

10 32 1.5 94 3.2 4.8 1 23 299 321 299 321 0.97

11 32 0.00016 0.0097 15.7 4.3 1 23 327 349 327 349 0.99

12 32 0.00047 0.029 14.2 2.0 1 23 355 377 355 377 0.98

13 32 0.00024 0.015 15.1 1.5 3 23 385 405 383 405 0.96

14 32 0.00086 0.053 13.4 0.9 1 23 411 433 411 433 0.98

15 32 0.012 0.77 9.7 3.2 3 23 441 461 439 461 0.98

16 32 0.0011 0.066 13.1 3.6 3 23 467 487 466 487 0.98

17 32 0.77 48 4.1 1.7 2 23 494 516 493 516 0.89

18 32 0.018 1.1 9.2 0.9 1 23 578 600 578 600 0.96

19 32 0.0003 0.018 14.8 0.6 1 23 604 626 604 626 0.97

20 32 0.00085 0.053 13.4 4.9 1 23 628 650 628 650 0.98

21 32 0.027 1.7 8.7 3.2 1 23 656 678 656 678 0.95

22 32 4.6e-05 0.0028 17.4 3.3 1 23 684 706 684 706 0.98

23 32 0.0006 0.037 13.9 1.3 1 23 712 734 712 734 0.98

24 32 0.024 1.5 8.8 8.0 1 23 740 762 740 762 0.97

25 32 0.00079 0.049 13.5 1.9 1 23 768 790 768 790 0.98

26 32 0.00054 0.034 14.0 1.5 3 23 798 818 796 818 0.96

27 32 2.7e-05 0.0017 18.1 2.4 1 23 824 846 824 846 0.98

28 32 0.00036 0.022 14.6 5.2 1 23 852 874 852 874 0.98

29 32 0.00047 0.029 14.2 1.7 2 23 881 902 880 902 0.96

30 32 7e-05 0.0043 16.8 1.2 1 23 908 930 908 930 0.98

31 32 0.01 0.62 10.0 8.4 1 23 936 958 936 958 0.97

32 32 5.4 3.3e+02 1.4 1.2 3 20 966 983 964 987 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	32	0.0061	0.38	10.7	1.2	1	23	26	48	26	48	0.98
2	32	0.0051	0.32	10.9	1.4	3	23	77	97	75	97	0.96
3	32	0.00017	0.01	15.6	2.2	2	23	104	125	103	125	0.97
4	32	0.00024	0.015	15.1	5.7	1	23	131	153	131	153	0.98
5	32	1.4e-05	0.00087	19.0	2.0	1	23	159	181	159	181	0.98
6	32	1.3	82	3.4	6.8	1	23	187	209	187	209	0.98
7	32	0.00015	0.0091	15.8	1.5	1	23	215	237	215	237	0.99
8	32	0.041	2.5	8.1	7.4	1	23	243	265	243	265	0.96
9	32	3.8e-05	0.0024	17.6	3.6	1	23	271	293	271	293	0.98
10	32	1.5	94	3.2	4.8	1	23	299	321	299	321	0.97
11	32	0.00016	0.0097	15.7	4.3	1	23	327	349	327	349	0.99
12	32	0.00047	0.029	14.2	2.0	1	23	355	377	355	377	0.98
13	32	0.00024	0.015	15.1	1.5	3	23	385	405	383	405	0.96
14	32	0.00086	0.053	13.4	0.9	1	23	411	433	411	433	0.98
15	32	0.012	0.77	9.7	3.2	3	23	441	461	439	461	0.98
16	32	0.0011	0.066	13.1	3.6	3	23	467	487	466	487	0.98
17	32	0.77	48	4.1	1.7	2	23	494	516	493	516	0.89
18	32	0.018	1.1	9.2	0.9	1	23	578	600	578	600	0.96
19	32	0.0003	0.018	14.8	0.6	1	23	604	626	604	626	0.97
20	32	0.00085	0.053	13.4	4.9	1	23	628	650	628	650	0.98
21	32	0.027	1.7	8.7	3.2	1	23	656	678	656	678	0.95
22	32	4.6e-05	0.0028	17.4	3.3	1	23	684	706	684	706	0.98
23	32	0.0006	0.037	13.9	1.3	1	23	712	734	712	734	0.98
24	32	0.024	1.5	8.8	8.0	1	23	740	762	740	762	0.97
25	32	0.00079	0.049	13.5	1.9	1	23	768	790	768	790	0.98
26	32	0.00054	0.034	14.0	1.5	3	23	798	818	796	818	0.96
27	32	2.7e-05	0.0017	18.1	2.4	1	23	824	846	824	846	0.98
28	32	0.00036	0.022	14.6	5.2	1	23	852	874	852	874	0.98
29	32	0.00047	0.029	14.2	1.7	2	23	881	902	880	902	0.96
30	32	7e-05	0.0043	16.8	1.2	1	23	908	930	908	930	0.98
31	32	0.01	0.62	10.0	8.4	1	23	936	958	936	958	0.97
32	32	5.4	3.3e+02	1.4	1.2	3	20	966	983	964	987	0.86

Sequence Information

Coding Sequence: ATGTTAAACTGTGTTCGAGAACAGTTGAAACACGATGGCACAGGGATGTCACAGAGTGTCGCAGTGTCGCTTGCGTATTCCTGCGTCGAGTGTGACTACGACTGTAACACCGATCTTGACCTGAGAAATCACATCAAGTCTCATACGTTTCTGTACGATTGCGATTACACGACTTTCGAAGACGGTACGAGCGAATCCTTCGGAGACGATGCGACTAAAGCCATCGCGTGCGGTCTGTGCGATTACAGATGCGACAGGCTACAGTCGATGAACCGGCACATGAAACTACATCCGGGCGAGAAACTTTTGTCGTGCAAATTCTGCGAGGTTACTTTCTCGGTACGACACGATTTGAAAGAACACATCAAGACGCACAAAGGCGATAAAAGGTACGAGTGTTCGACGTGTAATTACAAGTGTTCGCAAAGGAAAGATTTAAAGAAACACATTTTCACGCATACGGGAGAGAAGCCGTATTCCTGCAGCCTCTGCGATTACAGATGCTCGCGTCGGGATGCCTTGACGCAACACATGTTGGTCCATACCGGCGAGAAGCGATTCACCTGCGACTATTGCGAATACCGATCCTGGCACAAGTGCAGCATGCAAAAGCACATGTTGAAACATTCAGATGATAAGCCTTATTCCTGTAATTTATGCGATTACAGGAGTGTGCATCCTTCTTATATCGAAAAACACATGATGACACACACAGGAGAGAAGCCGTTCTGCTGTTATTTCTGTGATTATCGATGTACGCGTCAGAACGACATGCAGAAGCATATACTGAATCATACTGGCGAAAAGCCTTATACGTGTACAGTCTGTGGTTATAAATGTTCGCAGAGGTCGTATATGAAAAAACACATGGTGATACACACAGGGGAGAAGCCGTTTTGCTGTCAGCTCTGCGATTTCAGGTGTTCTTGGGAACGCAGTCTTAAGATGCATATGGCGAGCCATGCAGACTGGAAACCGTACAGTTGCGATTTCTGCGAGTACCGTTGCCCGCAGCCGTCGCACCTCAAGGAACACTTGAAAACTCACACGGGCGAGAAGCCGTTCAGTTGCAGCTTCTGCGATTACAAGAGCTCGAGACAGTCAACATTGAACATGCACGAAAAGATACACTACAGCGAGAAGAACATAGCTTGCGATTTCTGTGATTACAAGACGTTCAGACAGTACGATTTTCAGAAACACCTACGAACGCACACAGGCGAGAAACCGTTTTCGTGCGACTTCTGTGAGTACAAGAGTGCAAGGAAAAATTTACTTCAGATGCACATGGCAACGCACACTGGCGAGAAGCCGTTTGGCTGTTCGCACTGCGACTTTCGCACGTCGAACCGTTGGTACGTCAAAGAGCACATGAAAAAGCACACGCAGAAGCTCCTTTGCAATCTGTGCGACTACCAGTGCGCCCGGCAGATCCACCTCAAGAAACACATCGAAACGCATAAAAACCGAGAGACCATAGTCTGCAACCTCTGCCCTTATAAATGTTTGTCAAAACAACTTTTGAGAAAACACACCGACGAAACTCATAAAACAgTCTCTGAcctactttttatttacttttttaattccttGTCAGAGTTTGCTTgtgttatattttgtttttatactgaTGATGTGTTTATCTTAGGTTTTTTATTGATTTGTCTAAGGATTATGTTGAACTGTATTAAGAAAGAATTGGAAGATGATGATGACACAGTTTGCCCTGCGTACTCTTGTGTCGAGTGTGATTACAAATGTTATTCAGATTTCGAACTGAGGATTCATATTGAAGCGCATGATTCAGTTTTCTACTGCGACGACTGCGATTACAATACCAGTGTTCGAGACGAGTTCAAAAGGCATATCGCAAATCATGTTTTTTCATGTAGCCTGTGCGAGTATCAGTGTACGAGACGACAGTATCTAAAACGTCATATGATGCTCCATAAAGGTGAAAAGACATTTCTATGTGGCTACTGCGATTATAAGTGTTTGCAGAGGAAGGAGTTAAAAAGGCACGTCTTAACGCATACGGGCGAGAAGACTTTTTCATGCGATCTTTGCGATTACAAGTCATCTCGTCAGAACAACCTGCACAAGCATATTATGACGCATTCTGATGAAAAGCCGTATTCGTGCGGATTCTGCGATTACACAAGCTCGCAGCCTTATTACGTCAAGAAGCACATGGTGAAGCATACAGGGGAGAAGCCgttctgttgttttttctgtGATTATCGATGCGTAAGGAAGAACGATATGCAAAAGCACGTTAGAACGCACACGGGCGAGAAGCCGTATTCCTGTACACTCTGCGATTACAGAAGCTCGCAGATGTCTTATGTAAAGAAACACATGATAAAACACACTGGTGAAAAGCCGTTCGGCTGCGATATATGCGATTATCGTTGTTCGAGGCAAAACAGCCTCAAGATACACCTCGTCAGTCATACCGAGTGGAAACCGTACTCTTGCGATCAGTGCGATTACAGATGCCCTTTGAAATCCAATTTAAACCAACACATGAAAATACACACCGGTGAGAAACCGTATCACTGCGATCACTGCGATTATAAAAGCTCGCAGAGTTCGACGTTGAAACAGCACGTCAAAATACATTCGGGCGTTAAGGACATATCGTGCGAGTTGTGCGATTACAAGACTTTCCGTAGGTACGATTTTCAAAAGCATGTACGCACCCATTCGGGCGAGAAGCCGTTCTCGTGTGATGTATGTGAGTACAAGAGCTCGAGGAAGTCTGTACTTAAGAACCACATGCTCACCCACACCGGTGAGAAGCCGTTCTGCTGCTATCTCTGTGACTACAGGTGCGCACAGCAGAACCACCTTAAAAAACACCTTGAAACACACTCGAGGCGTGATTCTATCAATTGCGGCCTTTGCCCCTACAAATGTTTGTcgaaacaacttttaaaaaagcataGTGATGAAGTTCACAAAACATGA
Protein Sequence: MLNCVREQLKHDGTGMSQSVAVSLAYSCVECDYDCNTDLDLRNHIKSHTFLYDCDYTTFEDGTSESFGDDATKAIACGLCDYRCDRLQSMNRHMKLHPGEKLLSCKFCEVTFSVRHDLKEHIKTHKGDKRYECSTCNYKCSQRKDLKKHIFTHTGEKPYSCSLCDYRCSRRDALTQHMLVHTGEKRFTCDYCEYRSWHKCSMQKHMLKHSDDKPYSCNLCDYRSVHPSYIEKHMMTHTGEKPFCCYFCDYRCTRQNDMQKHILNHTGEKPYTCTVCGYKCSQRSYMKKHMVIHTGEKPFCCQLCDFRCSWERSLKMHMASHADWKPYSCDFCEYRCPQPSHLKEHLKTHTGEKPFSCSFCDYKSSRQSTLNMHEKIHYSEKNIACDFCDYKTFRQYDFQKHLRTHTGEKPFSCDFCEYKSARKNLLQMHMATHTGEKPFGCSHCDFRTSNRWYVKEHMKKHTQKLLCNLCDYQCARQIHLKKHIETHKNRETIVCNLCPYKCLSKQLLRKHTDETHKTVSDLLFIYFFNSLSEFACVIFCFYTDDVFILGFLLICLRIMLNCIKKELEDDDDTVCPAYSCVECDYKCYSDFELRIHIEAHDSVFYCDDCDYNTSVRDEFKRHIANHVFSCSLCEYQCTRRQYLKRHMMLHKGEKTFLCGYCDYKCLQRKELKRHVLTHTGEKTFSCDLCDYKSSRQNNLHKHIMTHSDEKPYSCGFCDYTSSQPYYVKKHMVKHTGEKPFCCFFCDYRCVRKNDMQKHVRTHTGEKPYSCTLCDYRSSQMSYVKKHMIKHTGEKPFGCDICDYRCSRQNSLKIHLVSHTEWKPYSCDQCDYRCPLKSNLNQHMKIHTGEKPYHCDHCDYKSSQSSTLKQHVKIHSGVKDISCELCDYKTFRRYDFQKHVRTHSGEKPFSCDVCEYKSSRKSVLKNHMLTHTGEKPFCCYLCDYRCAQQNHLKKHLETHSRRDSINCGLCPYKCLSKQLLKKHSDEVHKT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -