Basic Information

Insect: Cimex lectularius
Gene Symbol: -
Assembly: GCA_000648675.3
Location: NW:2910041-2914603[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 4.4 2.7e+02 1.7 5.0 1 23 13 35 13 35 0.94

2 17 6.9e-06 0.00043 20.0 0.5 1 23 41 63 41 63 0.99

3 17 0.00035 0.022 14.6 3.5 1 23 69 91 69 91 0.98

4 17 0.0019 0.12 12.3 3.3 2 20 98 116 97 119 0.95

5 17 2.2e-05 0.0013 18.4 4.2 1 23 125 147 125 147 0.98

6 17 0.001 0.065 13.1 0.9 1 23 153 175 153 175 0.92

7 17 4.4e-07 2.7e-05 23.7 0.5 1 23 181 203 181 203 0.98

8 17 4.6e-06 0.00029 20.5 1.3 1 23 209 231 209 231 0.97

9 17 1.7e-06 0.00011 21.9 2.0 1 23 237 259 237 259 0.97

10 17 5.1e-05 0.0032 17.2 4.5 1 23 265 287 265 287 0.97

11 17 4.7e-06 0.00029 20.5 1.2 1 23 293 315 293 315 0.99

12 17 1.7e-05 0.0011 18.7 5.9 1 23 321 343 321 343 0.99

13 17 2.3e-06 0.00014 21.5 1.3 1 23 349 371 349 371 0.99

14 17 3.4e-05 0.0021 17.8 4.9 1 23 377 399 377 399 0.98

15 17 2.3e-07 1.5e-05 24.6 0.1 1 23 405 427 405 427 0.99

16 17 6.3e-06 0.00039 20.1 0.3 1 23 433 455 433 455 0.96

17 17 0.02 1.2 9.1 0.9 1 23 461 483 461 483 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	4.4	2.7e+02	1.7	5.0	1	23	13	35	13	35	0.94
2	17	6.9e-06	0.00043	20.0	0.5	1	23	41	63	41	63	0.99
3	17	0.00035	0.022	14.6	3.5	1	23	69	91	69	91	0.98
4	17	0.0019	0.12	12.3	3.3	2	20	98	116	97	119	0.95
5	17	2.2e-05	0.0013	18.4	4.2	1	23	125	147	125	147	0.98
6	17	0.001	0.065	13.1	0.9	1	23	153	175	153	175	0.92
7	17	4.4e-07	2.7e-05	23.7	0.5	1	23	181	203	181	203	0.98
8	17	4.6e-06	0.00029	20.5	1.3	1	23	209	231	209	231	0.97
9	17	1.7e-06	0.00011	21.9	2.0	1	23	237	259	237	259	0.97
10	17	5.1e-05	0.0032	17.2	4.5	1	23	265	287	265	287	0.97
11	17	4.7e-06	0.00029	20.5	1.2	1	23	293	315	293	315	0.99
12	17	1.7e-05	0.0011	18.7	5.9	1	23	321	343	321	343	0.99
13	17	2.3e-06	0.00014	21.5	1.3	1	23	349	371	349	371	0.99
14	17	3.4e-05	0.0021	17.8	4.9	1	23	377	399	377	399	0.98
15	17	2.3e-07	1.5e-05	24.6	0.1	1	23	405	427	405	427	0.99
16	17	6.3e-06	0.00039	20.1	0.3	1	23	433	455	433	455	0.96
17	17	0.02	1.2	9.1	0.9	1	23	461	483	461	483	0.97

Sequence Information

Coding Sequence: ATGGATGAAGAAGAGGCGATTCCTAAGCAAAAGCGGTTTAAATGTTCGGAATGCCCCTACAGGACAGATTGCAAAAGGAGTCTGATGTTTCACACCCGTACTCATACTGGAGAACGGCCTTACAAATGCACGATATGCAGTTTTGCCAGCGCAAGATCCGGTAACCTGAGGAAACATATGGTGACGCATTCTGATGAAAAGCCTTATTCCTGCTTAGAGTGTGATTTCAAATGTGCTCGTGCCCATTACttaaaaaagcatattttgaTTCATtcgacagaaaaaaatatatcctgCCCAGAGTGCGACTACAAATGTTCACAGATTCGAAATCTCAAGAACCACATGGTGTGCCATTACGGTGAGAAGACGTTTACATGTACAATGTGCGATCATCGGTGCGCACGAGCGAGGGATCTTAAGAGGCACATGATGATTCACAAAGGTGACAAACGTTTCATCTGCATACAGTGCGGTTACGCTTGTGTTCAAGGGAGTACGCTCAAAAGACATATGATGTCACatacaaatgaaaaaccttTTATGTGCGAAGAGTGCAATGGGAAATTCACATCGGCTGGAAATCTGAGGAAGCATATGATGACGCATACCGGTGAAAAGCCTTACTCTTGCACAGAATGTGACTACAAATGTTCGCAAGCTGGGAATTTAAAAAGCCACATGGTAATTCACACGGGTGGTGAGGAACATCCTTGCTTGCTCTGTGACAGGGTTTGCACAAGAGCGAGTGATTTGAAAAGGCACATGATGGTACACTCAGGAGAAAAAAGGTTCTGCTGTGCTATTTGTGACTACACCTGTGCTAGATCAGCACATCTAAGGAATCACATGCTTATCCATTCCGGAGAGAAACCCTACTCTTGCACAGAATGCAACTATAAATGTGCCAGGGCAATTAACTTAAAAGCTCACATTATGACACATACCGGGGAAAAACCTTATACTTGCACCCATTGTGATTATAGATGTTCTCaggcttttaatttaaagacaCACATTCTGACGCATACGGGTTTCAAACCTTACTCTTGTACAATCTGCTCATACACGAGCACACAAGCTGTGAATCTCAAAACTCATATGAAAACACACACAAAGGAGAAGCCATTTTCTTGTGATTTTTGTGACTATGTATGCTCTCAGAACACACATTTGAGAAGGCACTTGATGATTCACACAGGTGAAAAACCGTACGTATGCCCTGACTGCGATTACAGAACTTCAGTGCCTAGCAATTTGAAAACGCATATCATGACTCATACTGGTGAAAAACCGCATAACTGTACTATATGCGATTACAGCTCGGCCCAGGCGAGTGCTCTTAAAAGACACATGGCGGTTCATTCGCGAGGCCAACATTTTTCGTGCGCGCTCTGCAATTATTCAGCTTTGTCCAAAAGAAGCTTAAAGAAACACATGACCATTCATTATAAAGACATCGATAATTCAATAGTTAAAGCTCTAGCCGATTCCGTTGACGGATCGACAGTTAATTCAAATCCAGATGATATTGAAATCGACAACATAAAAGAAGAGATGCTAGATTCAAATGAACGACAAACGAACAGTCCAGACAGTTGTAAAGGTATTAAATGTGAAAGCGAAGAAATTGTAgataacattgaaataaaaaatgaattttttatagatgaatATGAACCAAAGGAATTAAAAGTTAGTTAA
Protein Sequence: MDEEEAIPKQKRFKCSECPYRTDCKRSLMFHTRTHTGERPYKCTICSFASARSGNLRKHMVTHSDEKPYSCLECDFKCARAHYLKKHILIHSTEKNISCPECDYKCSQIRNLKNHMVCHYGEKTFTCTMCDHRCARARDLKRHMMIHKGDKRFICIQCGYACVQGSTLKRHMMSHTNEKPFMCEECNGKFTSAGNLRKHMMTHTGEKPYSCTECDYKCSQAGNLKSHMVIHTGGEEHPCLLCDRVCTRASDLKRHMMVHSGEKRFCCAICDYTCARSAHLRNHMLIHSGEKPYSCTECNYKCARAINLKAHIMTHTGEKPYTCTHCDYRCSQAFNLKTHILTHTGFKPYSCTICSYTSTQAVNLKTHMKTHTKEKPFSCDFCDYVCSQNTHLRRHLMIHTGEKPYVCPDCDYRTSVPSNLKTHIMTHTGEKPHNCTICDYSSAQASALKRHMAVHSRGQHFSCALCNYSALSKRSLKKHMTIHYKDIDNSIVKALADSVDGSTVNSNPDDIEIDNIKEEMLDSNERQTNSPDSCKGIKCESEEIVDNIEIKNEFFIDEYEPKELKVS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -