Basic Information

Gene Symbol
-
Assembly
GCA_035046065.1
Location
JAWNOJ010000013.1:10634448-10635616[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 7 0.27 19 6.0 0.9 1 23 154 176 154 176 0.96
2 7 0.0034 0.25 11.9 0.3 1 20 181 200 181 205 0.91
3 7 0.0043 0.31 11.6 5.5 1 23 217 240 217 240 0.97
4 7 0.0016 0.11 13.0 1.2 1 23 247 269 247 269 0.98
5 7 1.8e-06 0.00013 22.2 3.3 1 23 280 302 280 302 0.98
6 7 4.2e-05 0.003 17.9 0.7 1 23 308 331 308 331 0.98
7 7 3.9e-05 0.0028 18.0 1.0 1 23 337 359 337 359 0.98

Sequence Information

Coding Sequence
ATGAACGAAATATTGTGCAAGTTGTGTTTAATCACGACAACTTGCCGCCTTGAGTCAAAACCAAAGAATTTACCCAAAGATAAGACGTTATTACAGCACTTGTTGGACTTGTGCAACATAGAGctggATTTTGAGCAACTGTCTGAAACTATTTGTGAGAACTGCTTTAACAAGCTACTTAATATATACGAGACGCTGCATGGTTGGAAAAAAGCACAAACTGAACTTGTAGACGAAGATACAGAAGAGCACATTGATCTGGAGATTTCGTTGGAAATAGAGCAATTGCTATCGGCACAAATCAATTCATCACAAACGCCACCATTAGAAGCAACAGCTGCTGACGCTACTGATGATTTTGCACAGGCAACAAACaatattcaacattttgcGCTAGCTATTGGGCACAATGGTGCTATACTGGCTTGCATAGCAAAGTCGAACACCAAATCCCATATATTTGCTTGCTACTATTGCCAGGAACCACACAAGCGTGTTGTTCAATTGCTACAACATGCACAGACTCACAGCGAGCGCTGCTTTATGTGCCGCAAATGTGGccaagaatttgaaaaaattgagcaATTGCAGCAACACGAGTTGCTAGAACAACATACTAGCGCAGTTAAGCAGGAGCATGATGTGGACTATCGCTGTGTACAATGCGGCTGTGTGTTTGATCGCTTCTTTTGCCTAAGTCGTCATTATCGTGAGGTGCATCGCGACAAATCGAAATACTACAAATGCGATTTATGCGACGAGCAATTCAAGTACAAACCCATCTATGAAAAACATCTAAATCGCCATCTGGGCATTGAGCGTAAGCCCGCAACCACATACAGCTGCAGCCAATGCGACAAAAGTTTTGAGCGACGCTATCAGCTAACCACGCATTTTCGCCTGCATACCGGACAGAAGCCGTACAAATGTGAACCCTGTGGCAAGCTTTTTGCACATCGTGGTAATCTGGTGCTGCATTATCGCACCGTACATTCCAAGCAGCGTCCCTATGAGTGTGACTTGTGTTTGTCACGCTTTACCACCAACTCGTATCTCATGAAACATCTCATCACACATGGCACAATGGATTCTTCAGAAGATGTTCAGCAGCTGCAGTAG
Protein Sequence
MNEILCKLCLITTTCRLESKPKNLPKDKTLLQHLLDLCNIELDFEQLSETICENCFNKLLNIYETLHGWKKAQTELVDEDTEEHIDLEISLEIEQLLSAQINSSQTPPLEATAADATDDFAQATNNIQHFALAIGHNGAILACIAKSNTKSHIFACYYCQEPHKRVVQLLQHAQTHSERCFMCRKCGQEFEKIEQLQQHELLEQHTSAVKQEHDVDYRCVQCGCVFDRFFCLSRHYREVHRDKSKYYKCDLCDEQFKYKPIYEKHLNRHLGIERKPATTYSCSQCDKSFERRYQLTTHFRLHTGQKPYKCEPCGKLFAHRGNLVLHYRTVHSKQRPYECDLCLSRFTTNSYLMKHLITHGTMDSSEDVQQLQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-