Basic Information

Insect: Chymomyza fuscimana
Gene Symbol: zfh1
Assembly: GCA_949987675.1
Location: OX465088.1:130635944-130640307[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.7e-05 0.0028 18.6 1.0 1 23 151 173 151 173 0.97

2 15 0.0063 0.66 11.1 1.9 3 23 181 201 179 201 0.93

3 15 9e-05 0.0093 16.9 0.1 1 23 343 365 343 365 0.98

4 15 0.0018 0.19 12.8 0.6 1 23 371 393 371 393 0.98

5 15 6.5e-05 0.0067 17.3 4.5 1 23 423 445 423 446 0.94

6 15 0.00023 0.024 15.6 0.1 1 23 472 494 472 494 0.95

7 15 0.018 1.8 9.7 1.3 1 23 500 523 500 523 0.97

8 15 0.011 1.2 10.3 0.9 1 19 530 548 530 549 0.95

9 15 0.00016 0.016 16.1 5.6 1 23 558 580 558 580 0.97

10 15 0.046 4.8 8.4 0.3 3 23 587 607 585 607 0.96

11 15 9.1e-06 0.00095 20.0 0.3 1 23 616 638 616 638 0.98

12 15 0.001 0.11 13.6 0.1 3 23 646 666 644 666 0.97

13 15 5.5e-05 0.0058 17.6 0.5 1 23 672 694 672 695 0.95

14 15 0.012 1.2 10.2 0.1 1 23 705 727 705 727 0.96

15 15 0.0056 0.58 11.3 0.2 1 23 1268 1290 1268 1290 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.7e-05	0.0028	18.6	1.0	1	23	151	173	151	173	0.97
2	15	0.0063	0.66	11.1	1.9	3	23	181	201	179	201	0.93
3	15	9e-05	0.0093	16.9	0.1	1	23	343	365	343	365	0.98
4	15	0.0018	0.19	12.8	0.6	1	23	371	393	371	393	0.98
5	15	6.5e-05	0.0067	17.3	4.5	1	23	423	445	423	446	0.94
6	15	0.00023	0.024	15.6	0.1	1	23	472	494	472	494	0.95
7	15	0.018	1.8	9.7	1.3	1	23	500	523	500	523	0.97
8	15	0.011	1.2	10.3	0.9	1	19	530	548	530	549	0.95
9	15	0.00016	0.016	16.1	5.6	1	23	558	580	558	580	0.97
10	15	0.046	4.8	8.4	0.3	3	23	587	607	585	607	0.96
11	15	9.1e-06	0.00095	20.0	0.3	1	23	616	638	616	638	0.98
12	15	0.001	0.11	13.6	0.1	3	23	646	666	644	666	0.97
13	15	5.5e-05	0.0058	17.6	0.5	1	23	672	694	672	695	0.95
14	15	0.012	1.2	10.2	0.1	1	23	705	727	705	727	0.96
15	15	0.0056	0.58	11.3	0.2	1	23	1268	1290	1268	1290	0.97

Sequence Information

Coding Sequence: ATGAACAATCAAGACTATGGCGGCATTCAGTGGATACAACACCACGCCTCTGTGGTTGAATCGGAGGATGATATATTGGAGAACGGCGATGGCAATGACGCCGCCGAAAATGTTGCGTATCTTGTGAATGATAGCGAAAGGGATGAGGATTTGGACCACATGGCAGCCGAAAATCTAATTTTCATGGCACGCGATGGTCAGTTAAGCGAAATTATAGACGCAAGTGGTACTAGTGGCACAGTGCTGGTTGCTGATGATGGCACTGCCGTGGCCTATGCAGAGTCATTTGATGATGATGCCCAGGTTGTCACTGAGGAGGTCATTACTGACGACTGGGTGCAGCATCAAGGGGCGGAGCGCGTGGAAATTGCCGCAGAACAAATTGCTGGCCCTAGCAGTTCACAGGAGCTCTTGGATATGGAACAAGATGAGTACACAGCCTTGCGTCCATATCCCTGTGATTTTTGCAGTCGCCGTTTTCGCAAAAAGGCCAGTCTTAATAATCATATGCTAGCGCATCAAAACGACAGACCGCATTTATGCAGACTTTGTGGTGCTAGATTCTCACGACGCGAAGAGTTATATAATCATTTCAAGGCTCATGCCGAGGCACAAGATGCAGCCGATGCAAAGGCCATTCTAGAGGCCACTGCTGCTGTTAAATTTGAGCCGCAGCATAGATTCTTGGACGATCATTACTATGAACACGAGTGGCCTTCTTCGTATCAGGAGCCTGTGGCAAATAATACCAGCCCCAGTCAAACCAACTACTTGACAGGCGAGAACTGCCATGCAGCACCGACTGTGCAACGTGGACGCATTAGTCGGCTAAAGCCTAAAGAGGAGGCATCGCAATACATTGTAACTGCCGATAAGCCATCTATGGCTGAGCTGGAGTATATGGAGTGCTCAGAGTCACAGCCAACAGCGTCCTCAGCTGACTTAACCCAAACCATACGCGCAACACAGCAACAGCCAGCTGTTGCGCAGCTTGCACGCTTTCCTGTGCTGGACGATAGTAAGCCGTTTGTTTGTCAGCAGTGTGGTTTGGCATTTGCGCGGGAGAAGGCCTTGGTGTCCCATATAAAGAACCATCGGGTGGATTCGCCATTTGAGTGCAACCAATGCCAAGAGATGTTTTGGGATAACAACAGTCTGCTGGAGCACCAGAAAACACATAAATTTGAGGAAAGTAATTCGGAATACGATCCTACCTCAGCTGAAGACAGTGCTTCCGATTCAGAGCCAGAGCAGTTGtatggtgactttttttgcaacgaTTGTGGCATTAGTTTTCATAGGCAGGATCTTCTTCGCCGCCATGCCAAGCAGCACCACAAGCAACCCACGGCCGTTTTGAAAAATTCGCCTATAACTGCCGATAGTGTCAACGAGGATGCCAAAGATTCAGAACATAGCTGTACGACATGTGGCAAGTCTTTTCCTAGTGCGTTGGAGCTACTAGCTCACGCAGAAATTCATGCGCGTTTCCCGCCCTTTAAATGCGTGCTGTGCGGCGTAAGTTTCTATGAGGAACAAGCCATTAAGCGTCACTTACACACACGCCATCCCCATGAGCTAAAGCCACATTCGTGTGTGCTCTGCGGCAAAGAGTGTCGTGATCGCAAGGCCCTAATCAAACATGCTTGGGATCACTCTCGTGAAAAGTGTCATTCGTGCTCCAAGTGTGGCAAGAACTTTCACAACAAAGCGCGCTTGAAGCGTCACATGGCCTCACATCGTGATAAATCGGTTATCTGTGAAGTCTGCCAGGAAGAGTTTCCCGATGGTCGTTCCCTGTCCAATCATAGACACTCGCATAGCACTACTTCAACTGGCAAACTGTTCCCGTGTAATGAGTGCGGCAAAACGTTCGGCTCGCGCAGCTCACAGCAGATCCATGTGcgcatacatacaggtgaaagACCATATGGTTGTCGTTATTGCTGGAAAGCTTTTGCAGATGGCGGCACATTGCGCAAACATGAGCGTATTCACACCGGAGAGAAGCCCTATGCGTGCTCCGTGTGTCCACGTGCCTTTAATCAGCGCGTGGTTCTGCGTGAGCACATACGCTCACACCACTCGGGCATGGATGCGACGCGAGGAACTTATTTTTGCCCTGTGTGTTCCGCAAATCTGTCGACATCGAATGAGCTTATACAACATCTTATCCAGCACAGCGACTCCAATACAGCCAAGCAGCGGCAGCCAGTTACTGGGCCGCGTAAATACAAGCGCCGTCGAAAGCTACAGCCACATGAGATTGCGCATAGGCGCGGTGAAAATCAAAACGGCGAGGGGGAGGAATATACCAGTGATATGGATATGTGTGAATTTGATGTAGACAATGTGGATGATTTATTAGAAATGGCGGAGTCACCAACCAAGTCCAGCAACAAGGCCAAGCGTAAGAAGGGCAATGCATGCTCAAAATCAGTCACAAATGGTAAACACTTGGAAATGACAGGACAAGCTACACAAGCCATGGATCGCAATAAAACGGATAATGTCAAGGCACGTTATGACTCTACTAGCAGTAACTCGGATCGTTTGTGGGCAGAAAAGTTTATGCAGAACGCTAATCAAACTGCTGACGACGCACTCTTTCAGATTGACTCTCTGGTAGTAGTCAACGATACCACCTTGCCAGCAAGCAGTATCTCAGGTGTGACCAAAACGCGTCGTAGTGGCAAGCAGCCAATTAATAGATCTAATCATTTGACCAATAAACCTACAGCAGCGTCTGAGCCAAAGGTCAACAACAGCGCAACCTCCGGCAGCAATAGtcgtagcaaaaaaaaaccaaccaaagCAGCCAAGTCTGAGTCAAACACAAGCTCTCGTCCGCGCATGATTCACACAGAAAAGTCACGTGTGCCGGCTGCTACACAGGAATCAGCAAGCAACGCTAAGAAGTCGCGTTCAAAGACCTATTTAGCACGCTCGGATACTAGCAGCATTGGTTTGCTGCCTGGCGTAAAATCCAGCAGTACTGCGCGCACTAGCACATCGACTATTGTAGATGATTATGAAATAATATCGCCCGCCACACAGCCTCCCAACCAGATCAGTTCCAGTCCTTTGCATATAAAACaagagcaggagcagcagcgtGTGCAACTTATGTACGATGACACGCATCTGCTGATTGATACTGCTTTACTGCGTGAAAAAGCCTATGAAAAGTTTAATCCAAGCATTGTCAATGATCTGGAGGAGATTTTGCGCTCACCACTTAAATCCGAACGAAACATGCGCCTGCGTTTTACCAGCGAAAGCTCAACAACACCACAATTCCTGCCGGAGGAGGATCAAAACATGATCAAGATTGAGCCCACATCGCCAGATTTGCGCGAAATGATAGAGAGCCAACAGCGCATTATGAGTAGTTCAAGCTCGTCAGCGCGGACCACGCGCCATCTCAGACAGCCAAGTGATAATAGAAAATATCAGCTAGAGAACAGCAGCACGGTGCCAAGTCACTCAAGAGCCTCGACAAAACGTGGCAGCAATAAGCTGGCGAGCAGCTCTGCGCAGAAAAAAAACACTACCATGATACGCTCGCAGTCTGCAGCGCGTACCACAACCAAAACGAATTCAGCGAGCAGCTCAGCTACCTCATCGTCATATCTTAGCTATGGGGAGGATTCTTACAATGTAAATGTACCTGCCAGCTCCAATACTGCTGATGTAAGCTCGGGCTTTTTTTCCATATCCGAAGTTGTCTCTGCGGCAGATGCAGCTGATGCTGCCGCCAAAGCAGCTGCTGCTGGTAAGCCGGAGCGCAAGACGCGTTCCTTTGAGTGCGAAATGTGTTCGGCCATCTTCTACGATCGCGCCCAGCTACTGGATCATGTTCACATTCATATTTAA
Protein Sequence: MNNQDYGGIQWIQHHASVVESEDDILENGDGNDAAENVAYLVNDSERDEDLDHMAAENLIFMARDGQLSEIIDASGTSGTVLVADDGTAVAYAESFDDDAQVVTEEVITDDWVQHQGAERVEIAAEQIAGPSSSQELLDMEQDEYTALRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCRLCGARFSRREELYNHFKAHAEAQDAADAKAILEATAAVKFEPQHRFLDDHYYEHEWPSSYQEPVANNTSPSQTNYLTGENCHAAPTVQRGRISRLKPKEEASQYIVTADKPSMAELEYMECSESQPTASSADLTQTIRATQQQPAVAQLARFPVLDDSKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNNSLLEHQKTHKFEESNSEYDPTSAEDSASDSEPEQLYGDFFCNDCGISFHRQDLLRRHAKQHHKQPTAVLKNSPITADSVNEDAKDSEHSCTTCGKSFPSALELLAHAEIHARFPPFKCVLCGVSFYEEQAIKRHLHTRHPHELKPHSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVICEVCQEEFPDGRSLSNHRHSHSTTSTGKLFPCNECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGMDATRGTYFCPVCSANLSTSNELIQHLIQHSDSNTAKQRQPVTGPRKYKRRRKLQPHEIAHRRGENQNGEGEEYTSDMDMCEFDVDNVDDLLEMAESPTKSSNKAKRKKGNACSKSVTNGKHLEMTGQATQAMDRNKTDNVKARYDSTSSNSDRLWAEKFMQNANQTADDALFQIDSLVVVNDTTLPASSISGVTKTRRSGKQPINRSNHLTNKPTAASEPKVNNSATSGSNSRSKKKPTKAAKSESNTSSRPRMIHTEKSRVPAATQESASNAKKSRSKTYLARSDTSSIGLLPGVKSSSTARTSTSTIVDDYEIISPATQPPNQISSSPLHIKQEQEQQRVQLMYDDTHLLIDTALLREKAYEKFNPSIVNDLEEILRSPLKSERNMRLRFTSESSTTPQFLPEEDQNMIKIEPTSPDLREMIESQQRIMSSSSSSARTTRHLRQPSDNRKYQLENSSTVPSHSRASTKRGSNKLASSSAQKKNTTMIRSQSAARTTTKTNSASSSATSSSYLSYGEDSYNVNVPASSNTADVSSGFFSISEVVSAADAADAAAKAAAAGKPERKTRSFECEMCSAIFYDRAQLLDHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00336126;
90% Identity: iTF_00336126;
80% Identity: -