Basic Information

Gene Symbol
-
Assembly
GCA_035041775.1
Location
JAWNKW010000148.1:1586693-1591567[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 4.4e-05 0.0034 17.8 0.8 2 23 168 190 167 190 0.96
2 10 0.0042 0.33 11.6 6.7 1 23 197 220 197 220 0.95
3 10 0.091 7 7.4 0.7 3 20 234 251 232 253 0.90
4 10 0.018 1.4 9.6 0.2 1 23 270 293 270 293 0.95
5 10 0.011 0.84 10.3 3.8 3 23 392 412 391 412 0.96
6 10 0.0063 0.49 11.0 0.0 1 23 428 451 428 451 0.97
7 10 0.00014 0.011 16.3 1.7 1 23 457 480 457 480 0.97
8 10 5.7e-06 0.00044 20.6 2.0 1 23 486 508 486 508 0.96
9 10 0.0012 0.093 13.3 4.6 1 23 515 537 515 537 0.98
10 10 0.024 1.9 9.2 0.0 1 20 543 562 543 564 0.93

Sequence Information

Coding Sequence
ATGTACACTGCTGCAAATATAGACAAGTTTTGCCGCATTTGCATGCGGCAACTAGCTCTATTTGGGAATGAGCAAGAAACCAGCCATAACACTGAATCGTTACCTGAAATAGCTTACGAGCTTCAACACTTCTTTGCCATAGACGTCTTTAAGCCGTACATTTTACTTtccaaaaacatttgcattttatgctaCCGTACAATAGCTCACTTTAAGGAGCTATGTGCTGTGGCTCAGCAAAGCACAGATGTATTAACACGCCTTGCCATTGCTAATGGGAACCACAATGCTGATGCCGGACGTACTTTGCTTACAGCGGATGATTACTTGGCTCAAGTTGAAGTGCTTTTGGAAGAAAAACCAGTAGTAGCAGAGTCAATTGACAATGAGGATGCTGAATCAAAATCAAGGGACAACAGTTTCCCTCAACTCCAGCCCACATCGATTGATTTAGCTAGCACATTGTTTACAAGCAATCTCCCCGACAAGCGTATTCCTCTCGTTTGTCCTCAATgtggaaaacaatttttcaagtcACACTTTTTGGAAGCGCATGTACGCAGCGTACACGAGGGTGATCCTGAGCCCTTTTGCTGTCGTGACTGTGACATATCTTTTAAGCGTTATGACCTGCTGCGCTCCCATAACCAAAAGTGCCATCCAGAATCTATTGAAAACCATGCCAATAGAATTATAATTTGCGAGCATTGCAAAAGTGAgttcaaaacaaagaaagcGCTGGGTGAACATTTCAAGCAATATAAGGATCACAAACCACCCAGGGCTGTGCTTCCCAAATCGGAGAAGTTTAAGTGTCCTCAGTGCCCCCagttatttacatttaagACCGCAATACCCCGGCATGTACGAGTCGTGCATGAAGGAAGGCGTCCTCTTTTTGATTCGCACTTTAAGGAGCTATGTGATGTGGCTCAGCAAAGCACAGCTGTATTAGCAAGCCTTGCCATTGCTGATGGGAAACACAATGTTGATGCCTTAACGACTTTGCTTACAGCGGATGATTACTTGGCTCAATTTGAAATGCTTGAGGAAGCAGAGCCAACAGAAGCGGAGTCAATTGGCAATGAAGATGGTGAATCAAATTCGAGCGTCAACAGTTGCCCTGAACTTCAGGCCCCATCGATTGATTCAGCAGGCgatagcaacaaaatttgcgAGCATTGCAAAAGTGagtttaaaacaaagaaagcgCTGCGGGAACATTTTAAGCAACATAAGGATCACAAACCACCCCGTAATATGATTCCCGAATCGAAGAAGTTCAAGTGCCCTCAGTGTCCGCAGCTATTTGCATTTAAGGCCGGGATAGCCACGCATGTGAGAGTAGTGCATGAAGGCCAGCGTCGTTTCCAGTGCACACATTGTCAAAATAGATTTGCAACAAACGCTGCACTGTTGAATCATGAGCGTTCTTCACATATAGACAAACTGCCCCATTCTTGTAAGATATGCGATAAGCGTTATTCTACTTCTGATGAGCTGGACAAACATATTCTCTACCATGACCGGAATCTGTGGCGTTATACTTGCTCGATTTGCACCAAGAAATGTTTTACACGACAGAATTTGATCGACCATGAAAAGCGACATAAAGGGGATAAACCATTTATATGCCCAAATTGCAGCTTGGGCTTTGGTACTGAAGAACTACTAGCCAAGCACAAGGAAGTGCCATGTGCTGATCGCACGCTAAGATTgcgtaaaaaaaagtaa
Protein Sequence
MYTAANIDKFCRICMRQLALFGNEQETSHNTESLPEIAYELQHFFAIDVFKPYILLSKNICILCYRTIAHFKELCAVAQQSTDVLTRLAIANGNHNADAGRTLLTADDYLAQVEVLLEEKPVVAESIDNEDAESKSRDNSFPQLQPTSIDLASTLFTSNLPDKRIPLVCPQCGKQFFKSHFLEAHVRSVHEGDPEPFCCRDCDISFKRYDLLRSHNQKCHPESIENHANRIIICEHCKSEFKTKKALGEHFKQYKDHKPPRAVLPKSEKFKCPQCPQLFTFKTAIPRHVRVVHEGRRPLFDSHFKELCDVAQQSTAVLASLAIADGKHNVDALTTLLTADDYLAQFEMLEEAEPTEAESIGNEDGESNSSVNSCPELQAPSIDSAGDSNKICEHCKSEFKTKKALREHFKQHKDHKPPRNMIPESKKFKCPQCPQLFAFKAGIATHVRVVHEGQRRFQCTHCQNRFATNAALLNHERSSHIDKLPHSCKICDKRYSTSDELDKHILYHDRNLWRYTCSICTKKCFTRQNLIDHEKRHKGDKPFICPNCSLGFGTEELLAKHKEVPCADRTLRLRKKK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-