Basic Information

Insect: Chymomyza amoena
Gene Symbol: topi
Assembly: GCA_037043745.1
Location: JBAMAX010000543.1:74152-76571[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 5.4 5e+02 1.9 2.0 2 19 100 116 99 119 0.90

2 11 2.9e-06 0.00027 21.7 1.1 2 23 186 207 186 207 0.97

3 11 0.93 87 4.3 0.8 2 23 234 255 233 255 0.89

4 11 0.035 3.3 8.8 0.1 2 19 324 341 323 343 0.95

5 11 0.012 1.1 10.3 4.0 1 23 392 416 392 416 0.91

6 11 6.7 6.2e+02 1.6 0.2 2 20 431 449 430 453 0.79

7 11 4.6e-07 4.3e-05 24.2 1.9 1 23 477 499 477 499 0.95

8 11 0.00027 0.025 15.5 0.8 1 23 505 530 505 530 0.96

9 11 0.4 37 5.5 1.7 1 23 536 558 536 558 0.88

10 11 6.7e-08 6.2e-06 26.8 0.5 1 23 564 586 564 586 0.99

11 11 0.0016 0.15 13.0 2.0 1 23 592 615 592 615 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	5.4	5e+02	1.9	2.0	2	19	100	116	99	119	0.90
2	11	2.9e-06	0.00027	21.7	1.1	2	23	186	207	186	207	0.97
3	11	0.93	87	4.3	0.8	2	23	234	255	233	255	0.89
4	11	0.035	3.3	8.8	0.1	2	19	324	341	323	343	0.95
5	11	0.012	1.1	10.3	4.0	1	23	392	416	392	416	0.91
6	11	6.7	6.2e+02	1.6	0.2	2	20	431	449	430	453	0.79
7	11	4.6e-07	4.3e-05	24.2	1.9	1	23	477	499	477	499	0.95
8	11	0.00027	0.025	15.5	0.8	1	23	505	530	505	530	0.96
9	11	0.4	37	5.5	1.7	1	23	536	558	536	558	0.88
10	11	6.7e-08	6.2e-06	26.8	0.5	1	23	564	586	564	586	0.99
11	11	0.0016	0.15	13.0	2.0	1	23	592	615	592	615	0.96

Sequence Information

Coding Sequence: atggaatCGGAAGAAATAACATTCGAGTTCGCACCTGGGGCCGTAGTTAACGATGAGGAAATGTTCAGAATTTTGGGATCTGCAGGGCATTTGCCAATTCGGTCTTTGACTGATCCGTTTTTAACTGAGGTGGTGCAAGAGGTGGAAAGCAATTCGGATTATAATGCAGaagaagagcaaaaaaaattgcacgATTTTTTGACTGGTGTCGGGCAATGCAAATTAGCTGCTGatgaaaatggcttaaaaaCTTCTGCTCAAGATATACCAGTCTCAGCAGGAAGCTACTCCTTAATTAAATGTGTCAATTGCAACAGACTCTTTGACTCGACTAGTTTTCAAAATCATTCTTGCAACTATGATTTGAATAAACTTCTTGAACATACTCCAATACAAGACAAGCCAACAGTGGGTATAGAAATTCCTCCTAAGAAGACGTGCAGCGACCGCGTTATTACGGAAAATCAAATACGATTACGTCGCTATTTGAAGGATGAGTTTAAGCATGACCTGGCATCTGGTGAGACTCGAATCAAAAAGTCCAAGGGCCCTAACGAGTGCAATATATGCGAGCGCAAGTTTGTACATCCTTCAGGCTTAAACCGCCACATGGAAAAACACGCGCTAGATCTTATTCCCGCACAGATAAGTAGTTCTGTAAATGGACTTACAGTTGCGCATGGCTTGCGTGTAGTATTGCAGTGCATACACTGCGGTCGTGTTTTTTGCGAAATACAGACAGCTCTGGATCATATTTTAGTGCACTTTCCGAAACATTCACCAGCTCCTATAGCCAATTTGGAACTTACAACAGATGAGGAGAATATTGAAGAAAGTGTTTTGGATCAAATCTTGAAGGAAGGCGAAAGTCTTCTATCATGCTTCGCTGATGGAACAGACTCCTCCGTACTCCAACAGACAGATACTTCCAATTTTTGCTTTGTCAATCTTATTGTAAGCAGTGTGTTACAGTGTGAATTTTGCGAATATATCTTCGTGGACATTTCGCATCTCTTAGTGCACTCAGCTTGCCATTTACCTGAGCGCCGCTTCGAATGTACTGCTTGTGATATACAAATGACGACGTCAAAAGAAGCTAGCACCCATTTTCAAACTGATTGCGTTTTTATGCGCGAAGGTGCAAAACATTTACAGATCTCACTGCATcgttattttgtttgcaatgTATGCGAACTAAAGTTTACCAGTACCGAACTGCTGCAGGAGCACCGCCATACCTGTTACCATTATTTTCCTCGCTTGAGCAAGAGCCGTATGCGCCTCTTGCTGCCCTGTGAATTTTGCGAAGCTGTCTTTGAATATTCCCATGAAATACAACCGCATTACGAAGAAaagcatttaaacaaaaaaaaacgtgatAAGGATTTACGCAGCAATGCCAACGGAGTTGCTGGACGCTTGCGACAGTACCTCTGTGATATTTGTGGCAAGTCTTACACTCAGTCTAGTCACTTATGGCAACATTTACGCTTTCATCAAGGTGTCAAGCCTTTTGTATGTCAAGAAGATGGCTGTGGGCGCAAGTTTACAATTCGCCCGGATTTAAATGATCACATTCGCAAATGCCACACGGGGGAGCGCCCTTACCATTGCCTGGTATGTGGCAAGCGTTTCTTAACTGGGTCTGTCTTTTATCAACATCGTCTTATACACCGCGGCGAGCGGCGTTATGAGTGTGAACAATGTGGCAAGCGTTTCTATCGTGCCGATGCACTCAAGAATCATCAGCGTATTCATACTGGGGAAAAGCCGTATAGCTGTTTGTTTTGTACCAAAACATTCCGCCAGCGTGGAGACCGTGATAAGCACATACGTGCACGACACTCGCATTTAGATGACAACACGCGTTTAATAATGCAAATACAGAAGTTCCAACTAGAGGCTCAAGCCGCCGCCGAGCAGGCAAAGAAGGTCCAGGAAAGTACCATGACGTTTCCGTTAATACCGCAAGGTTTGGCTGTAAATGAAATTGGACCTGACAGTTTTATTGAGGCTTCAAATGTGATATTGCCTCAATTTGTACAGCTAGCCAATCGTGAAGTCCAAAATGTTGTACACCAGGATTCCGATTTACCTATTATTCATCTAAATGACCAGGTTAGCGTTGAGTCGGAGATAGCAAGCAATTGCGCCACTAATATATCAGTTAAGGATCGGAATTGTGAGAAGGCAAAAGTGGTTGTTGTGGATAATAATGGTCCCAAACcgtttttcttttga
Protein Sequence: MESEEITFEFAPGAVVNDEEMFRILGSAGHLPIRSLTDPFLTEVVQEVESNSDYNAEEEQKKLHDFLTGVGQCKLAADENGLKTSAQDIPVSAGSYSLIKCVNCNRLFDSTSFQNHSCNYDLNKLLEHTPIQDKPTVGIEIPPKKTCSDRVITENQIRLRRYLKDEFKHDLASGETRIKKSKGPNECNICERKFVHPSGLNRHMEKHALDLIPAQISSSVNGLTVAHGLRVVLQCIHCGRVFCEIQTALDHILVHFPKHSPAPIANLELTTDEENIEESVLDQILKEGESLLSCFADGTDSSVLQQTDTSNFCFVNLIVSSVLQCEFCEYIFVDISHLLVHSACHLPERRFECTACDIQMTTSKEASTHFQTDCVFMREGAKHLQISLHRYFVCNVCELKFTSTELLQEHRHTCYHYFPRLSKSRMRLLLPCEFCEAVFEYSHEIQPHYEEKHLNKKKRDKDLRSNANGVAGRLRQYLCDICGKSYTQSSHLWQHLRFHQGVKPFVCQEDGCGRKFTIRPDLNDHIRKCHTGERPYHCLVCGKRFLTGSVFYQHRLIHRGERRYECEQCGKRFYRADALKNHQRIHTGEKPYSCLFCTKTFRQRGDRDKHIRARHSHLDDNTRLIMQIQKFQLEAQAAAEQAKKVQESTMTFPLIPQGLAVNEIGPDSFIEASNVILPQFVQLANREVQNVVHQDSDLPIIHLNDQVSVESEIASNCATNISVKDRNCEKAKVVVVDNNGPKPFFF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00338658; iTF_00337821;
90% Identity: iTF_00337821; iTF_00338658;
80% Identity: -