Cfes043770.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Chrysotoxum festivum
Gene Symbol
tbx1-b
Assembly
GCA_963931855.1
Location
OZ007556.1:86048593-86098112[+]

Transcription Factor Domain

TF Family
T-box
Domain
T-box domain
PFAM
PF00907
TF Group
Unclassified Structure
Description
The T-box encodes a 180 amino acid domain that binds to DNA. Genes encoding T-box proteins are found in a wide range of animals, but not in other kingdoms such as plants. Family members are all thought to bind to the DNA consensus sequence TCACACCT. they are found exclusively in the nucleus, and perform DNA-binding and transcriptional activation/repression roles. They are generally required for development of the specific tissues they are expressed in, and mutations in T-box genes are implicated in human conditions such as DiGeorge syndrome and X-linked cleft palate, which feature malformations [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 3.3e-83 2.7e-79 267.1 0.1 1 182 135 322 135 322 0.96
2 2 2.8 2.3e+04 -3.2 0.4 84 106 344 366 327 384 0.45

Sequence Information

Coding Sequence
ATGCATCAGACGGCTTATCGTCGAGCAATGTCATCAGATTGCACTTCTATGGTAGCTTCGATGTCACCTTTCATCGAAAATGGATTAAATTCGAGTTTTACGGAATGCTGTTATACTGCTGCACCGGATTATTGGACTGGATCTTATGGAAACAGTGCCATTAGTCCAATGAAACAAATTGAAGCATGCATCCAAACAGCAGGGAAAGATCGGTCTTCATATAAACCTCTTGAGCACATAGCAATCAATTCCAAGCATCCTGAGGAAAGTAGCTGCCAGGATAACCGCACAAACaatgaaaatattaacaataatAGCAGCAATGGAAAGAAGTACAAATCAAAAAAGGATACAATCAACAAAAACGATGAAATCGTTCACCCATCTGTAGCCCAAGCTGTGGTCATTCTTGAAACTAAGCAGCTGTGGGATAAGTTCCACGAACAAGGAACCGAAATGATTGTCACGAAAACCGGTAGGCGAATGTTTCCAACATTTCAAGTTCGAATTGGTGGCCTAGACCCGCAGGCAACATACATCATGATGATGGATTTCGTCCCAGTTGATGATAAACGCTATCGATATGCATTCCATAATTCCAGTTGGGTTGTTGCGGGTAAAGCTGATCCAATTTCACCACCGCGCATCCATGTACACCCGGATTCCCCAGCACCCGGTACTAATTGGATGAAACAAATCATTTCGTTTGACAAACTCAAGCTCACCAACAACCAACTCGATGAAAATGGCCACATAATATTGAACTCGATGCACAGGTATCAGCCAAGATTCCACATTGTCTACCTGCCACCTAAAAATACATCTTTGGATGAGAATGAACACGCCAGCCATTTTCGCACTTTCGTCTTTCCGGAAACATCGTTTACGGCGGTCACTGCCTATCAGAATCAGAgaGTTACCCAGCTAAAAATTGTGAGTAATCCATTTGCTAAAGGATTCAGAGATGACGGAACTAACGACgtaaCATCAAGCAACATGAGTATAAGCCAAATGAATCATGATAATCATAATCGTATGAAGCACCACACACAACAGCAACCATCACATCAGCCACAATTAAATCAATTGAAGCTCTCATCGAAAGATTCGAATTTAGAGTTAGATGCACATCAAAATTCACTGCAAGTGACAGCTCCCCTTCCTCCCGCAACCACTGCCCATAATAATGCTTCACCCGAATTGGGATACCATTGCAGCAATGGCATAAAAACTGATGTAGCAAATGCAGCTGCGGCTGCCTCGACAGCAACCCTCAACAACACCCAAATGAATAGCCTGGTGACAAACGGGACCAATATATACTCCGCCATAGGGCAATCCTATACCAGCGATAGTAGCAACTTCGGAGCGATCTATCATCACAATCATCACCATTTGTCTCATGGCCACGGTTATGGGAATCCGTATGATTTTAAAAGTAAAGTGCCAGGTCATATGCGTCAGACGAATCCCTACAGTACGTATCAGACTTTCTATGGCAGTCCCCACCATCAGATGGTTCGACCCAATGGATACATTGACTTGGTTCCAAGGTGA
Protein Sequence
MHQTAYRRAMSSDCTSMVASMSPFIENGLNSSFTECCYTAAPDYWTGSYGNSAISPMKQIEACIQTAGKDRSSYKPLEHIAINSKHPEESSCQDNRTNNENINNNSSNGKKYKSKKDTINKNDEIVHPSVAQAVVILETKQLWDKFHEQGTEMIVTKTGRRMFPTFQVRIGGLDPQATYIMMMDFVPVDDKRYRYAFHNSSWVVAGKADPISPPRIHVHPDSPAPGTNWMKQIISFDKLKLTNNQLDENGHIILNSMHRYQPRFHIVYLPPKNTSLDENEHASHFRTFVFPETSFTAVTAYQNQRVTQLKIVSNPFAKGFRDDGTNDVTSSNMSISQMNHDNHNRMKHHTQQQPSHQPQLNQLKLSSKDSNLELDAHQNSLQVTAPLPPATTAHNNASPELGYHCSNGIKTDVANAAAAASTATLNNTQMNSLVTNGTNIYSAIGQSYTSDSSNFGAIYHHNHHHLSHGHGYGNPYDFKSKVPGHMRQTNPYSTYQTFYGSPHHQMVRPNGYIDLVPR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01211957;
90% Identity
iTF_01396529;
80% Identity
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