Basic Information

Insect: Chrysops caecutiens
Gene Symbol: ZEB2
Assembly: GCA_963971475.1
Location: OZ020567.1:18491889-18493802[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.00017 0.04 15.7 1.0 1 23 249 271 249 271 0.99

2 10 9.6e-05 0.023 16.5 1.6 1 23 276 298 276 298 0.99

3 10 5.4e-06 0.0013 20.4 3.8 1 23 303 326 303 326 0.97

4 10 8.7e-06 0.0021 19.7 0.1 1 23 332 354 332 354 0.96

5 10 4.8e-06 0.0012 20.6 4.1 2 23 361 382 360 382 0.97

6 10 6.2e-05 0.015 17.1 0.2 1 23 402 424 402 424 0.99

7 10 1e-05 0.0024 19.6 1.1 1 23 430 452 430 452 0.98

8 10 4.5e-06 0.0011 20.6 0.8 1 23 458 480 458 480 0.98

9 10 1.9e-05 0.0047 18.7 4.4 1 23 486 508 486 508 0.97

10 10 2.6e-06 0.00064 21.4 2.6 1 23 514 536 514 536 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.00017	0.04	15.7	1.0	1	23	249	271	249	271	0.99
2	10	9.6e-05	0.023	16.5	1.6	1	23	276	298	276	298	0.99
3	10	5.4e-06	0.0013	20.4	3.8	1	23	303	326	303	326	0.97
4	10	8.7e-06	0.0021	19.7	0.1	1	23	332	354	332	354	0.96
5	10	4.8e-06	0.0012	20.6	4.1	2	23	361	382	360	382	0.97
6	10	6.2e-05	0.015	17.1	0.2	1	23	402	424	402	424	0.99
7	10	1e-05	0.0024	19.6	1.1	1	23	430	452	430	452	0.98
8	10	4.5e-06	0.0011	20.6	0.8	1	23	458	480	458	480	0.98
9	10	1.9e-05	0.0047	18.7	4.4	1	23	486	508	486	508	0.97
10	10	2.6e-06	0.00064	21.4	2.6	1	23	514	536	514	536	0.98

Sequence Information

Coding Sequence: ATGACAGCGGATGTGTGCCGTGTGTGCGAAGACCCAACtgcaaacaaaaatattttcagtccAAAAAACAAGCATATACAGAAAAAATTAGCCGCTTGTGCCGATATTGAATTATCTGTATTAGATGACCTACCAAAGTTTATTTGCGAAAAATGTCAAGATACCTTGAACATTGCATATGATTTTAAAGTACAAGTGGAATATACAGATAGAAAATTACGTTCAGCAAAGAAGGGACAACCGCCTACGGACATAGTCACGATTTCACAGCTGAAAgttgaaaatgatttcaaagTTGAAGCAGACATATCGATGGGCTCGATACAGGAATATAGCAATATTGGTTACCAGGAAACTGAAAAGTTTTATGTCAAAGAAATGAATGATAATGAATTGGATTTCCCTGATAGCGAGAGCGAGTTTGGACATATAGTCGATGATAACAGTATCGACGATGATATCACCCTCAGTCCAATAAGTTTAAAATCGGAGTCTGAAACTTATCATGACGATGATATAATAGACATTACCCAATTCAATACACAGGATAATACTGACTACAATTTGTCGTTTGAATGTGAACAGTACAAAGCAGAAAAGTTGGATCCTGATGAAAATAAAGATGAGAATCGGATTGATAGACCTACAATAGATTCCCAGAAAAAAGTTGCTGGTCCGGGTTCAAgtagaaaaccaaaaaaagcACGAAAACCAAGGGAAACTAAACCAGAAAGAGATAAGAAATATCGCTGTTCAACTTGTAACGAACCATTTATTAGTTTTCCTGAGTTTCAAAGTCACCAAAAATCACATGGAGCCAAAAGATTTAAATGTGAGATATGTGAAAAATggttttcaaaaaaatatagaCTTCAAGTGCATTTACAAACCCATGAAAAGCGAGAATATCCTTGCACAGATTGTGACAAAAAATACAGCAATATTGGAAACCTACATAGGCATATCAGgcattttcataaaaaagAAAGGCTATACATGTGCAGTGAATGTGGCTTATCTTTCAACAGATCAGCGTTATTAGAACAGCATTATGGTATTCACATAGACGAGAAGAATATTCCTTGTGACCTGTGTGATAAAAAATTTAAAACGAGACATCATTTGGTAGCACATAAGAGAACTCACATACCTATAGAAGAACGGCGTCAACGACGCCGTAAACCAATAGATCCTTCTGTCCAGTATGTGTGTCAGTATTGTGGTAAAATATCCGGTAATCCTTATTTAGCTAAAAATCACTTGAGAACACATACCGGTGAACGACCGTACGAATGTAAACTTTGCTCCAAGAAATTCGCATTTCAACAATCTTTGAATGTTCATATGACAGTGCATACTGGAGAACGACCATACAAATGCAATCAGTGCGATGCAACTTTCAAGCAACTTGGTCATTTAAATGGTCACATATTGATACACACTGGTGTAAAGAAACATGAATGCAATTATTGCCACAAGGCATTTCGTCTTAAAAGTAGTCTAACAATACACGAAAGGTTACATACTGGGGAAACGCCTTACAAATGTCCTGTATGTCATAAAAAGTACGCTGATCCTTCTACTTTTCGAAAACACAAAGCGACTCACGGAAATGTGCCTGAGGAGCCAATTGTCAATGATCAAACTACTAGAGATATATCAGAATATTTTGGTGAAGATTGTACCGAACTAGGTGAAATTATCGAGATGCATTCAGCGGTTGAagaaaagtaa
Protein Sequence: MTADVCRVCEDPTANKNIFSPKNKHIQKKLAACADIELSVLDDLPKFICEKCQDTLNIAYDFKVQVEYTDRKLRSAKKGQPPTDIVTISQLKVENDFKVEADISMGSIQEYSNIGYQETEKFYVKEMNDNELDFPDSESEFGHIVDDNSIDDDITLSPISLKSESETYHDDDIIDITQFNTQDNTDYNLSFECEQYKAEKLDPDENKDENRIDRPTIDSQKKVAGPGSSRKPKKARKPRETKPERDKKYRCSTCNEPFISFPEFQSHQKSHGAKRFKCEICEKWFSKKYRLQVHLQTHEKREYPCTDCDKKYSNIGNLHRHIRHFHKKERLYMCSECGLSFNRSALLEQHYGIHIDEKNIPCDLCDKKFKTRHHLVAHKRTHIPIEERRQRRRKPIDPSVQYVCQYCGKISGNPYLAKNHLRTHTGERPYECKLCSKKFAFQQSLNVHMTVHTGERPYKCNQCDATFKQLGHLNGHILIHTGVKKHECNYCHKAFRLKSSLTIHERLHTGETPYKCPVCHKKYADPSTFRKHKATHGNVPEEPIVNDQTTRDISEYFGEDCTELGEIIEMHSAVEEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -