Basic Information

Gene Symbol
zfy1
Assembly
GCA_905475395.1
Location
FR997754.1:131508193-131510991[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 8.8e-05 0.0019 18.9 1.3 2 23 211 232 210 232 0.96
2 11 1.6e-05 0.00035 21.2 1.1 1 23 240 262 240 262 0.99
3 11 0.0044 0.095 13.6 0.2 2 23 269 291 268 291 0.96
4 11 0.022 0.48 11.4 1.5 2 23 297 318 296 318 0.97
5 11 3.2e-05 0.00069 20.3 0.9 2 23 324 345 323 345 0.96
6 11 3.4e-06 7.4e-05 23.4 4.5 1 23 351 374 351 374 0.96
7 11 0.0027 0.058 14.3 0.3 3 23 409 430 408 430 0.92
8 11 0.00022 0.0048 17.7 0.6 1 23 439 462 439 462 0.97
9 11 0.00044 0.0095 16.7 0.7 2 23 469 491 468 491 0.96
10 11 3.1e-05 0.00067 20.4 5.7 1 23 497 519 497 519 0.97
11 11 1.5e-05 0.00032 21.3 1.2 1 23 525 547 525 547 0.98

Sequence Information

Coding Sequence
ATGAATACTACAATAAATATAAACGATTTTGATAAAATTTGTCGAATTTGTTTAATAATCAAAGAAAATATGATTGAAATATCAACACGTGAAATAATACATATGTTAGAGGAATGTACTTCTGTACAAGAATCGAGAGATCTGAAATTACCTGAACACATATGCCTTGAATGTTCTTGGCAATTAAAAACCGCTTACGATTTTAAAAAACAATGCAACGTATCACGAGAAATTTTATATTCAATATTAAGAAAAGAGGAAAATTGTAAAGAAAATATTAAGACTGAATTATATGAAGACTTTTCAACTAAAACAGAACTATATCCATACAGCGAGGTTGAAACGTTATTAACCGAAGATACAAAAGAAAATTGCATCGAAACTAAGACTGAGATAATTAATAATGAAATAAGTAAATTAAATTCAGAGGATTCAAATGACTGTGAAAAATACTCTGATGATGAAATCCAAGGAGGTGACGATTCATCTGAAGAAGATGAAGAATCAAATGATGAAGATGAATCAAAACATACCGAAGAATCGGATGACAATGAGAATCATGAAGGTTACGATCGTAAACAACGATCTTTAGCTGATATTTTGCTCAAGAAATACAAAATTTATGGATTAACGTGTAATATATGTCATAAGGAAATTAGTACAAGATCTACGTTATTACGTCACATGGAAATTCACGATCAAAATCGTGCGCTGAAATACAAGTGCAATCTTTGTAATAAAGGATTCTATGCTGAGGAAAATTTAAAGAAACATATAAATCGTCATATGGGTAAAACAAAGCTACAATGTGATTTATGTCCGAAACGATTTTACGTGCTAAGTGCACTCGGTGTACATTACAAGTCTAGTCATAAAATTAAACCGAAACGTTGTACACGATGTCCTTTGGAATTTTACCACCCTTTACAATTAGAACAACATGAACAGACTCACGATGAGAAAAAATTAATCTGTGATGTATGCGGAAAAGTTTTTCCAAAGAAAAATAAATTAACACGACATAAAAAGAATCATACACAAGATCGACCGTTTACGTGTTCAATCTGTAATAAATGTTTTAAAACAAAGGGCAGCTTACAAACACATATCAAATTACGTCACGAAGAAACGGATCGTCGTGAAATGTGCTATATTTGTGGGAAATTAGTACCAGTTGGAACATTTACGGTACACTTAGAGACACATAAAGATCGTAGTGTTGCATGTCCTGAATGTGATAAAGTTTTTGCAAATAAAATTATCTTAGAACGGCATATTTACCATAAACATACCGATGATGGTAGTGCCACGAAATTTTATTGTAAAATATGTAACAAAGGTTTAGGTAGTAAGGGTACATTGTCAACGCACATGCGTATTACGCACTCGGAAGCGAAAAAAATTGAATGTCATATATGTGGGAAAGCGTATAAATTGGTATCGCATGTTAATGTACATATTAAAAGTGCCCATATGGATATTAGACCGCATATATGTCAAACATGTTCGAAAGCTTTTCATAGTAAGTCTGAATTGAAAAATCATATGCGTACGCATACTGGAGAACGGCCATTTCCATGTCATATATGTGGTAAAGCGTTTGGATTTAAAACTGTACTTAAAACTCATATGAAAGTACACTCAAAATAA
Protein Sequence
MNTTININDFDKICRICLIIKENMIEISTREIIHMLEECTSVQESRDLKLPEHICLECSWQLKTAYDFKKQCNVSREILYSILRKEENCKENIKTELYEDFSTKTELYPYSEVETLLTEDTKENCIETKTEIINNEISKLNSEDSNDCEKYSDDEIQGGDDSSEEDEESNDEDESKHTEESDDNENHEGYDRKQRSLADILLKKYKIYGLTCNICHKEISTRSTLLRHMEIHDQNRALKYKCNLCNKGFYAEENLKKHINRHMGKTKLQCDLCPKRFYVLSALGVHYKSSHKIKPKRCTRCPLEFYHPLQLEQHEQTHDEKKLICDVCGKVFPKKNKLTRHKKNHTQDRPFTCSICNKCFKTKGSLQTHIKLRHEETDRREMCYICGKLVPVGTFTVHLETHKDRSVACPECDKVFANKIILERHIYHKHTDDGSATKFYCKICNKGLGSKGTLSTHMRITHSEAKKIECHICGKAYKLVSHVNVHIKSAHMDIRPHICQTCSKAFHSKSELKNHMRTHTGERPFPCHICGKAFGFKTVLKTHMKVHSK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01061024;
90% Identity
iTF_01061024;
80% Identity
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