Basic Information

Gene Symbol
-
Assembly
GCA_905475395.1
Location
FR997756.1:49782876-49786911[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.0011 0.024 15.4 0.5 2 23 242 263 241 263 0.96
2 15 1e-05 0.00022 21.9 1.4 1 23 269 291 269 291 0.98
3 15 0.034 0.74 10.8 2.5 1 23 297 319 297 319 0.95
4 15 0.0061 0.13 13.1 1.0 2 23 353 374 352 374 0.96
5 15 0.064 1.4 9.9 4.7 2 23 381 402 380 402 0.95
6 15 0.0012 0.027 15.3 2.6 1 23 408 430 408 430 0.98
7 15 0.0042 0.092 13.6 0.7 1 23 464 486 464 486 0.95
8 15 0.0012 0.026 15.3 1.6 2 23 493 514 492 514 0.95
9 15 2e-05 0.00043 20.9 2.8 1 23 520 542 520 542 0.99
10 15 0.00011 0.0023 18.6 1.0 1 23 548 570 548 570 0.98
11 15 2.1e-06 4.6e-05 24.0 1.0 1 23 576 598 576 598 0.98
12 15 6.4e-06 0.00014 22.5 1.7 1 23 604 626 604 626 0.96
13 15 5.1e-06 0.00011 22.8 2.2 1 23 632 654 632 654 0.98
14 15 0.00012 0.0027 18.5 0.2 1 23 660 682 660 682 0.98
15 15 3.2e-05 0.00069 20.3 5.7 1 23 688 710 688 710 0.98

Sequence Information

Coding Sequence
ATGGATACAAAGTTACGGTTACCAGATTTAAAAACTAACTTACAGAAAATTTGTAGAACTTGTTTGATAGGAAAAGACAATTTACAAACAATTTTTCGTATTTTAGATTTATTAAGAGAATGTACTTCAATACAAATTAATATGGATGATAATTTACCAAAATTAATTTGTCTCGATTGTACTAACAAACTTAATACTGCATTTGAATTCAGACAACAATGTGAAGTGTCTGAAAAAATTTTGTTACAACTGAGGGAATTCGGAGAAACACCTGAAATTACTGTTAAACTAGAAAGTAACGAATCAAATTCTCTAATACAAATAGAAAATTTAGAAACAAATGAAATATATATCAAATCGGAGAACTCTTACAATACAAATGAAAATAATTTCGATGAGTATAATAATAATGAATTTAACGATGTTCATTCAACCAGTGTACATTCGGTTTTCGAAACTTCTCTTAGTGAAACTAAAAATATGTCGGACGTATCAAAGACACAAAACATTCGATTAGAAAATGAAAATGTTAACCTCTCGAAGAATTATTCACCTTTAAATATAATACTAAAGGCCAAAAACGAAGAATCTCATGAAGATAATGATAGTGATATTTCTTGGCAAAGTAGTGATGAATCTGTAACTTTAAGAAAAAGTAAACGTTATACAAAATCTAGTAAACTAAAAAACGAGGCAGAGTTGGAGATAACAAAAAATGGATTATCATGTTCAAAATGTAAAAAATCTTTTGAATTAGAAACAGATCTAGAGATTCATATATTGAAACATAAAACGTTTAATGACTTTATTTGTCCTAAGTGTTCAAAATCTTTTGAAAACTCAATAAAGTTAAAAAGACATCTTAGCACACATATGACTAACAAGCCCTATAAATGCAATTTTTGTGATAAAACTTTTATTGCTGCTTGCGACAGAAATCGTCATTCCCTAGTTCATATTGGTAATAAAGATAACGATATTTTCGTACAAAATAGTGATGAAGCTATAGCTTTAAGAAAAACTGAATATAATAGAATTATAATAAAAAATGGACTTTCATGTCGTCAATGTAAAAAATTTTTTGAATTGGAATCTGATTTAGAAATTCATATGTTTAAACACCAAAAATTTGATGAATGTATATGTCCCAAATGTTGCAAGTCTTTCGAAAATGAAACAAAGTTAAAAAGACATCTTGACATACATCTGATTAAGAAACCATATAAATGCAACGTTTGTGAGAGAAGTTTTATTACAGTTCATGACAGAAAGCGTCATTTACTAAGTCATAAGGAAAAAACGTATAGCGATAATATTCCTATTCAAAATAGTGATGAATCTATGAATTTACGAACAAATGAATTTGAAAACATTACAATAGAAAATGGATTTTTATGTTCTCAATGCAAAAAGTTTTTTGAATTAGAAGAAGATTTAAAAATTCATATATTAAAACATCAAAAATTTGATGATTTGATTTGTCCTAAGTGTTCAAAGTCTTTCGAAAACGAGCAAGGTTTAAAACATCATTTTGATACACATCTGATTCACAAACCGTATAAATGCAATTTTTGTGATAAAAGTTTTGTTAATTCTGATGATCGAAATCGTCATTCTCGTACTCATACAGGTGAAAAACCTTATGTATGTTCGACTTGTGGAAAACGATTTACAGATGGCCGTAGATTGTCAGCACATATGAAATATCATCTTGGAGTTAGAAGTTTTGTGTGTACAATTTGTTCTAAATCATTTATATTTAAACGAGAGCTTCGAATTCATATGCGTATACATACTGGTGAAAAGCCTTATTTATGTATGGAATGTGGAGAAAGTTTTAGTCAATCCTACAGCTTAACTAAACATAAACGAAAACATACGGGAGAACGTCCATATTCATGCACAGAATGTGATAAAAGTTTTACATTAAATAAATATTTAAAAACGCATATGCTGTCTCACACTGGTGAAAAACCTTATATGTGTAAAATTTGTGATGCCAGCTATACTTCGTCTGGTTCTCTTATTATACACAATCGATCACATACTGGGGAGAGACCTTTTTCTTGTAATGTTTGTGAAAAGACTTTTAAATCAAGAAAACATTTGCTACAACATAAACGAACGCATAATAAAATATTGTGA
Protein Sequence
MDTKLRLPDLKTNLQKICRTCLIGKDNLQTIFRILDLLRECTSIQINMDDNLPKLICLDCTNKLNTAFEFRQQCEVSEKILLQLREFGETPEITVKLESNESNSLIQIENLETNEIYIKSENSYNTNENNFDEYNNNEFNDVHSTSVHSVFETSLSETKNMSDVSKTQNIRLENENVNLSKNYSPLNIILKAKNEESHEDNDSDISWQSSDESVTLRKSKRYTKSSKLKNEAELEITKNGLSCSKCKKSFELETDLEIHILKHKTFNDFICPKCSKSFENSIKLKRHLSTHMTNKPYKCNFCDKTFIAACDRNRHSLVHIGNKDNDIFVQNSDEAIALRKTEYNRIIIKNGLSCRQCKKFFELESDLEIHMFKHQKFDECICPKCCKSFENETKLKRHLDIHLIKKPYKCNVCERSFITVHDRKRHLLSHKEKTYSDNIPIQNSDESMNLRTNEFENITIENGFLCSQCKKFFELEEDLKIHILKHQKFDDLICPKCSKSFENEQGLKHHFDTHLIHKPYKCNFCDKSFVNSDDRNRHSRTHTGEKPYVCSTCGKRFTDGRRLSAHMKYHLGVRSFVCTICSKSFIFKRELRIHMRIHTGEKPYLCMECGESFSQSYSLTKHKRKHTGERPYSCTECDKSFTLNKYLKTHMLSHTGEKPYMCKICDASYTSSGSLIIHNRSHTGERPFSCNVCEKTFKSRKHLLQHKRTHNKIL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-