Basic Information

Gene Symbol
-
Assembly
GCA_905475395.1
Location
FR997758.1:16906292-16908913[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 25 4.6e-06 9.9e-05 23.0 0.7 1 23 177 199 177 199 0.97
2 25 6.8e-06 0.00015 22.4 0.8 1 23 205 227 205 227 0.97
3 25 8.6e-06 0.00019 22.1 1.3 1 23 233 255 233 255 0.98
4 25 1e-06 2.2e-05 25.0 1.5 1 23 261 283 261 283 0.98
5 25 8.6e-06 0.00019 22.1 1.3 1 23 289 311 289 311 0.98
6 25 4.5e-06 9.7e-05 23.0 1.7 1 23 317 339 317 339 0.97
7 25 0.00071 0.015 16.1 5.9 1 23 345 367 345 367 0.98
8 25 0.0007 0.015 16.1 0.9 1 23 373 395 373 395 0.97
9 25 9.2e-06 0.0002 22.0 3.1 1 23 401 423 401 423 0.98
10 25 1e-06 2.2e-05 25.0 3.6 1 23 429 451 429 451 0.98
11 25 1.6e-05 0.00035 21.2 3.1 1 23 457 479 457 479 0.98
12 25 7.2e-06 0.00016 22.3 1.2 1 23 485 507 485 507 0.98
13 25 1.6e-05 0.00035 21.2 3.1 1 23 513 535 513 535 0.98
14 25 1.5e-06 3.3e-05 24.5 0.9 1 23 541 563 541 563 0.98
15 25 7.2e-06 0.00016 22.3 1.2 1 23 569 591 569 591 0.98
16 25 7.2e-06 0.00016 22.3 1.2 1 23 597 619 597 619 0.98
17 25 7.2e-06 0.00016 22.3 1.2 1 23 625 647 625 647 0.98
18 25 1.6e-05 0.00035 21.2 3.1 1 23 653 675 653 675 0.98
19 25 1e-06 2.2e-05 25.0 3.6 1 23 681 703 681 703 0.98
20 25 7.2e-06 0.00016 22.3 1.2 1 23 709 731 709 731 0.98
21 25 1.6e-05 0.00035 21.2 3.1 1 23 737 759 737 759 0.98
22 25 1.5e-06 3.3e-05 24.5 0.9 1 23 765 787 765 787 0.98
23 25 0.0007 0.015 16.1 0.9 1 23 793 815 793 815 0.97
24 25 2.1e-05 0.00046 20.9 2.4 2 23 822 843 821 843 0.97
25 25 1e-06 2.2e-05 25.0 3.6 1 23 849 871 849 871 0.98

Sequence Information

Coding Sequence
ATGGCAAATAATTCATTTTTTGATACAAATAATTATTTGTTTATTAATAAAGATAATATTAAAGTTGAAAAAGAATTACATACAGAACTAATTATTAAAAATGAAATATTAGATGAAACTATTTTAATGGAAGGTGGACAAATTACAAATAAAGAAGAAGGCAGCAATGATAGTGATAGTGTTGTGAGTGTAAAACATGAACTTGTGAGTGATGAAAATGATAAACAATTGTACACAATTAATTATGAAAATATTAAACTTGAAAAAGAATTACATACAGAACTAATTATTAAAAATGAAATATTAGATGAAACTATTTTAATGGAAGGTGGACACATTAAAATAAAGGAAGAAGGCAGCAATGATAGTGATAGTGTTGTGAGTGTAAAACATGAACTTGTGAGTGATGAAAATGATAAACAATTGTACACAATTAATTATGAAAATATTAAACTTGAAAAAGAATTACATACAGAACTAATTATTAAAGATGAAATATTAGATGAAACTGATTTAGAAGAAAAACCATTTGTATGTGATATTTGTAATAAAACATTTAATGAGAAAAGTAATTTAGTTAAACATAAACTTATTCACAGTAAAGAAAAACCATTTGCATGTGATATTTGTAATAAAACATTTAATGAGAAAGGTAATTTACTTAAACATAAACGTATTCACACCGGAGAAAAGCCATTTTCATGTGATGTTTGTAATAAAACATTTAATGAGAAAGGTAATTTACTTAAACATAAACGTATTCACAGCGGAGAAAAGCCATTTTCATGTGATGTTTGTAATAAAACATTTACTCAGAAAAGTAATTTAGTTTTACATAAACGTATTCACAGCGGAGAAAAGCCATTTTCATGTGATGTTTGTAATAAAACATTTAATGAGAAAGGTAATTTACTTAAACATAAACGTATTCACACCGGAGAGAAACCATTTGCATGTGATATTTGTAATAAACGATTTACTCGGCGAACTTCCTTAGTTAGACATAAACGTATTCACACCGGAGAGAAACCATTTTCATGTGAAAGTTGTAATAAAACATTTACTCAACAACATCATTTAGTTTTACATAAAAAGATTCATAGTGGAGAGAAACCATTTTCATGTGATGTTTGTAATAAAACATTTACTTGGCAAAGTGATTTAGTTGTACATAAAAGGTTTCATAGTGGAGCAAAACCATTTTCATGTGATATTTGTGATAAAAGATTTACTTCATCAACGCATTTAGTTACACATAAACGTATTCACAGCGGAGAAAAACCATTTTCATGTGATGTTTGTAATAAAACATTTACTACATCATCGCATTTAGTTAGACATAAACGTATTCACAGCGGAGAAAAACCATTTTCATGTGATGTTTGTGATAAAAGATTTACTTCATCAACGCATTTAGTTACACATAAACGTATTCACAGCGGAGAAAAACCATTTTCATGTGATGTTTGTAATAAAACATTTACTGATAAAAGTGTTTTAGTTAAACATAAACGTATTCACAGCGGAGAAAAACCATTTTCATGTGATGTTTGTGATAAAAGATTTACTTCATCAACGCATTTAGTTACACATAAACGTATTCACAGCGGAGAAAAACCATTTTCATGTGATGTTTGTAATAAATCATTTACTCAGAGAGGTGATTTAGTTAGACATAAACGTATTCACACCGGAGAGAAACCATTTTCATGTGATGTTTGTAATAAAACATTTACTGATAAAAGTGTTTTAGTTAAACATAAACGTATTCACAGCGGAGAAAAACCATTTTCATGTGATGTTTGTAATAAAACATTTACTGATAAAAGTGTTTTAGTTAAACATAAACGTATTCACAGCGGAGAAAAACCATTTTCATGTGATGTTTGTAATAAAACATTTACTGATAAAAGTGTTTTAGTTAAACATAAACGTATTCACAGCGGAGAAAAACCATTTTCATGTGATGTTTGTGATAAAAGATTTACTTCATCAACGCATTTAGTTACACATAAACGTATTCACAGCGGAGAAAAACCATTTTCATGTGATGTTTGTAATAAAACATTTACTACATCATCGCATTTAGTTAGACATAAACGTATTCACAGCGGAGAAAAACCATTTTCATGTGATGTTTGTAATAAAACATTTACTGATAAAAGTGTTTTAGTTAAACATAAACGTATTCACAGCGGAGAAAAACCATTTTCATGTGATGTTTGTGATAAAAGATTTACTTCATCAACGCATTTAGTTACACATAAACGTATTCACAGCGGAGAAAAACCATTTTCATGTGATGTTTGTAATAAATCATTTACTCAGAGAGGTGATTTAGTTAGACATAAACGTATTCACACCGGAGAGAAACCATTTTCATGTGATGTTTGTAATAAAACATTTACTTGGCAAAGTGATTTAGTTGTACATAAACGGTTTCATAGTGGAGCAAAACCATTGTCATGTGATATTTGTGATAAAAGATTTACTTCATCAACGCATTTAGTTACACATAAACGTATTCACAGCGGAGAAAAACCATTTTCATGTGATGTTTGTAATAAAACATTTACTACATCATCGCATTTAGTTAGACATAAACGTATTCACAATCGATAA
Protein Sequence
MANNSFFDTNNYLFINKDNIKVEKELHTELIIKNEILDETILMEGGQITNKEEGSNDSDSVVSVKHELVSDENDKQLYTINYENIKLEKELHTELIIKNEILDETILMEGGHIKIKEEGSNDSDSVVSVKHELVSDENDKQLYTINYENIKLEKELHTELIIKDEILDETDLEEKPFVCDICNKTFNEKSNLVKHKLIHSKEKPFACDICNKTFNEKGNLLKHKRIHTGEKPFSCDVCNKTFNEKGNLLKHKRIHSGEKPFSCDVCNKTFTQKSNLVLHKRIHSGEKPFSCDVCNKTFNEKGNLLKHKRIHTGEKPFACDICNKRFTRRTSLVRHKRIHTGEKPFSCESCNKTFTQQHHLVLHKKIHSGEKPFSCDVCNKTFTWQSDLVVHKRFHSGAKPFSCDICDKRFTSSTHLVTHKRIHSGEKPFSCDVCNKTFTTSSHLVRHKRIHSGEKPFSCDVCDKRFTSSTHLVTHKRIHSGEKPFSCDVCNKTFTDKSVLVKHKRIHSGEKPFSCDVCDKRFTSSTHLVTHKRIHSGEKPFSCDVCNKSFTQRGDLVRHKRIHTGEKPFSCDVCNKTFTDKSVLVKHKRIHSGEKPFSCDVCNKTFTDKSVLVKHKRIHSGEKPFSCDVCNKTFTDKSVLVKHKRIHSGEKPFSCDVCDKRFTSSTHLVTHKRIHSGEKPFSCDVCNKTFTTSSHLVRHKRIHSGEKPFSCDVCNKTFTDKSVLVKHKRIHSGEKPFSCDVCDKRFTSSTHLVTHKRIHSGEKPFSCDVCNKSFTQRGDLVRHKRIHTGEKPFSCDVCNKTFTWQSDLVVHKRFHSGAKPLSCDICDKRFTSSTHLVTHKRIHSGEKPFSCDVCNKTFTTSSHLVRHKRIHNR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-