Basic Information

Gene Symbol
Sall1
Assembly
GCA_958298965.1
Location
OY282587.1:8954679-8963839[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 21 0.92 1.4e+02 4.9 0.2 3 23 122 141 121 141 0.75
2 21 0.0075 1.2 11.5 0.9 3 23 146 166 145 166 0.95
3 21 0.00018 0.027 16.6 0.3 1 23 171 193 171 193 0.98
4 21 1 1.5e+02 4.8 3.8 1 23 197 219 197 219 0.98
5 21 0.038 5.8 9.3 0.9 1 23 225 247 225 247 0.93
6 21 3e-05 0.0045 19.1 1.0 1 23 253 276 253 276 0.94
7 21 0.0001 0.016 17.4 2.7 1 23 287 310 287 311 0.96
8 21 3.1e-06 0.00048 22.1 0.5 2 23 319 340 318 340 0.97
9 21 0.0031 0.47 12.7 2.6 1 23 346 368 346 368 0.97
10 21 0.026 4 9.8 0.5 3 23 395 415 393 415 0.94
11 21 0.0022 0.34 13.2 1.1 2 23 500 522 499 522 0.93
12 21 0.0051 0.78 12.0 0.3 1 23 547 569 547 569 0.98
13 21 0.86 1.3e+02 5.0 0.6 1 23 573 595 573 595 0.97
14 21 0.001 0.16 14.2 1.3 1 23 601 624 601 624 0.97
15 21 0.00099 0.15 14.3 4.5 1 23 630 652 630 652 0.96
16 21 0.0021 0.32 13.2 0.2 1 23 658 681 658 681 0.95
17 21 5.6e-05 0.0085 18.2 1.3 2 23 693 715 692 715 0.95
18 21 8.2e-05 0.013 17.7 2.0 3 23 729 749 727 749 0.96
19 21 8.8e-05 0.013 17.6 1.1 1 23 755 777 755 777 0.98
20 21 6.5e-07 9.9e-05 24.3 0.6 1 23 783 805 783 805 0.99
21 21 0.0003 0.047 15.9 0.6 1 21 811 831 811 832 0.96

Sequence Information

Coding Sequence
ATGATATTAATGGGCAAACTTATTAGGACATACCAGTTAAACGATAATGATTTGGAAGAAATTGTGATAACTATTGTTGACGAAGATTCGGAAGAATATACAGTTGAATATCCAGCTGGCTCTGAACCCATTGACATAAATGATTTCATAATCAACCTGAACACTGCTATAAAAAATGAACCGCCCGATATGGATAATTTGTTCAAAGAAACacttgaatcaaaaaataaatcctCTTTAACAGATCTTCTGTACATAAATGGTATACTCATGGACACATTTGATGACCACTATATGACCGAAGCTGAAACTGGTACATCTGATCCAAAAAAGAATAAacaaaacattctccatgacaGCTTGTGCGCTGTCTGTGGTAAAATGGTGAAGGATAAGAGTATGCGCAAGCACATTGCCAGTCATGGGACTGAACATTGTGATATTTGCAAGGCCTCTTTCAAAACAATTGAAGATCTGGAAAGTCATAAAGAATTGCACTTGAAAAACGCTTTTCCTTGTGACGTTTGTGGCCTGAGTTTCAAAAAGGCTAGAGATTTTGCTCTCCATACAAACAAACATTCCGGAGAATATTCCTGTCCAATGTGTAACTTCAGAACGAAGTGCAAAAGCTCTATAAGGGGACATATCAAGAGACATGAAGGAAAGTTCACTCATCATTGCACTATCTGCGGAAAGGGTTTTTTAGGTAAAGCGTTACTGATGACTCATGAGGAAATTCACCTGGACATCAAACGCTATGAGTGCGATCTTTGTGGTAAAAAATTCTCTGTTAAAAGGTACTTGCAAGTTCATCGTTCACTCAACCACAGGAAGGAACTGCTTGGTATTGATGGGCTCTACAAGTGTGGTCTGTGTGATAGGGAATTCAAATTCCTGAAAAGCCTGCGGCGCCATCAAAGCGTCATACATCACGTTGGTGAAGATCTCACCGTAGAATGCGAAGTATGCCATAAAGTAATCGCCAACAGTTATAACCTCAAAGTGCATATGCGCACTCACACTGGAGAGAAGAATTTCTGCTGTGATCTGTGTGGGAAAGCCTTTTCAGCCTTCaagtattggaaaaaacatACAGCGACACATGAAAGGCAGAAATCAGATAAAAGAAATGTTAAAAAAGCCGAAAGCCTGAGTGAATTCACCAGTTCGGCAAATTATGGCTGTAGATTTTGTGATGAAGAATTTCCTTCCAAAAAATCTTGGAGAAAACACGAATTGCTGCATGCAGCGTTGAATGAAGTACcaacagaagaagaagaagaaataaatatGATTGAAAGTGAAGATATTGAATTCGAgacTGACGTTATCAAATGCCTGGATGAAGATTGGGTGGCACCtaaaaggaaattgaaaaaattgaagctcGTCAAAAAGAAAACTATAAAGCTGAAGACGTCTcccaaagaaaagaaaataaaaaaacctgGCAAGTACATACCCAAGCTGAAACCCAATCACAAAGCAAGAGCTTGGGTATGTAAAATATGCTTTGAAGAGTTCAGTACAAGGAAAACCCTATTTGACCACAGAAAGTTTGTGCATGAAGACACTGAAGACGCGATAAAAGAAGAATTTGATTCTGCAAAGTACACATTTGATGCCACTCTTGAATTCTTCACTTGCAACAATTGTTCTGCGGAGTTTCAGACAAGAGAAGAAGTGGAAAAGCATGTGGAAACACATATAGAAAAGTATGAGTGTGTAAGATGTAACCTAATAATAAATGGAGCCTTACATTTCTCTTCCCATATGCAGACACACCGAATAGATGGACATTTTCCCTGTCCTTTATGTACCCACACTACTAGTAGGAAATCGGCTATGCTGACTCATATCCAGCGTATGCATTATAGAAAGTACGATTTTCAGTGTCGTACATGTGGTAAATGTTTTAACGATGCCACCACATTCAAAGAGCACGAAAACTTCCATTTGGGCGTAAAGCCTTTTATTTGTGTGGTGTGTAACAGAGAATTTATCTATTCACGATACCTCATAGCTCATCAGGTACGAAATCATAGGGTTCAGGTTCTGGATAAGGATTCGAAGACGCAGTGCCATATGTGCCCCAAAATGTTTGCTAGAAACGAAACGTTGGTCAAACACGTGGTCACTAAGCATTTGACTTTCCACGAAGGGCCTCATGAGAAGAAACACTTATGTGATGTATGCGGTCAAGGATTTTCAAGAACCGATAAACTGAAGATCCATTATAGGAAGCATACCGGTGAAAAACCTTATTCTTGCATGTATTGTAGCAAAAGCTTCATCAAACGAGACTACTTGATAATGCACGAAAGAATTCATAATGGTGAAAAACCGTATGTTTGTGATCATTGCGGAAAAAGTTTCAACCAGGGAGCTCCTCTGAGGATACATATGCGAACTCATACTGGTGAGCGACCCTACAAGTGCCCTCATTGTACCACTGGTTGCGTGTCTAAAGGGGCGCTGAACGCTCATATTAAAAGCTGTTTAAACTCATTCTGA
Protein Sequence
MILMGKLIRTYQLNDNDLEEIVITIVDEDSEEYTVEYPAGSEPIDINDFIINLNTAIKNEPPDMDNLFKETLESKNKSSLTDLLYINGILMDTFDDHYMTEAETGTSDPKKNKQNILHDSLCAVCGKMVKDKSMRKHIASHGTEHCDICKASFKTIEDLESHKELHLKNAFPCDVCGLSFKKARDFALHTNKHSGEYSCPMCNFRTKCKSSIRGHIKRHEGKFTHHCTICGKGFLGKALLMTHEEIHLDIKRYECDLCGKKFSVKRYLQVHRSLNHRKELLGIDGLYKCGLCDREFKFLKSLRRHQSVIHHVGEDLTVECEVCHKVIANSYNLKVHMRTHTGEKNFCCDLCGKAFSAFKYWKKHTATHERQKSDKRNVKKAESLSEFTSSANYGCRFCDEEFPSKKSWRKHELLHAALNEVPTEEEEEINMIESEDIEFETDVIKCLDEDWVAPKRKLKKLKLVKKKTIKLKTSPKEKKIKKPGKYIPKLKPNHKARAWVCKICFEEFSTRKTLFDHRKFVHEDTEDAIKEEFDSAKYTFDATLEFFTCNNCSAEFQTREEVEKHVETHIEKYECVRCNLIINGALHFSSHMQTHRIDGHFPCPLCTHTTSRKSAMLTHIQRMHYRKYDFQCRTCGKCFNDATTFKEHENFHLGVKPFICVVCNREFIYSRYLIAHQVRNHRVQVLDKDSKTQCHMCPKMFARNETLVKHVVTKHLTFHEGPHEKKHLCDVCGQGFSRTDKLKIHYRKHTGEKPYSCMYCSKSFIKRDYLIMHERIHNGEKPYVCDHCGKSFNQGAPLRIHMRTHTGERPYKCPHCTTGCVSKGALNAHIKSCLNSF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
-
80% Identity
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