Basic Information

Insect: Chrysolina americana
Gene Symbol: -
Assembly: GCA_958502065.1
Location: OY293412.1:92112929-92118407[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.9 3.2e+02 4.0 1.3 3 23 85 105 83 105 0.94

2 17 0.72 1.2e+02 5.3 4.4 1 23 111 133 111 133 0.98

3 17 0.63 1.1e+02 5.5 4.1 1 23 136 158 136 158 0.94

4 17 1.7 3e+02 4.1 1.3 2 12 165 175 164 186 0.79

5 17 1.9e-05 0.0032 19.8 0.2 2 23 196 218 195 218 0.92

6 17 0.41 72 6.1 0.6 2 23 228 249 227 249 0.96

7 17 0.0031 0.53 12.8 0.0 1 23 255 277 255 277 0.97

8 17 0.034 5.8 9.5 0.7 1 14 283 296 283 300 0.88

9 17 1.1 1.9e+02 4.8 4.3 2 23 374 395 373 395 0.96

10 17 0.34 58 6.3 4.8 1 23 401 423 401 423 0.98

11 17 0.069 12 8.5 2.0 1 23 426 448 426 448 0.97

12 17 0.019 3.4 10.2 1.2 2 23 455 476 454 476 0.94

13 17 0.007 1.2 11.6 0.3 2 23 486 508 485 508 0.96

14 17 0.17 29 7.3 0.7 2 23 518 539 517 539 0.97

15 17 7.1e-06 0.0012 21.1 0.1 1 23 545 567 545 567 0.97

16 17 0.00036 0.062 15.7 0.9 1 23 573 595 573 595 0.99

17 17 3.5e-06 0.00061 22.0 0.2 1 22 601 622 601 622 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.9	3.2e+02	4.0	1.3	3	23	85	105	83	105	0.94
2	17	0.72	1.2e+02	5.3	4.4	1	23	111	133	111	133	0.98
3	17	0.63	1.1e+02	5.5	4.1	1	23	136	158	136	158	0.94
4	17	1.7	3e+02	4.1	1.3	2	12	165	175	164	186	0.79
5	17	1.9e-05	0.0032	19.8	0.2	2	23	196	218	195	218	0.92
6	17	0.41	72	6.1	0.6	2	23	228	249	227	249	0.96
7	17	0.0031	0.53	12.8	0.0	1	23	255	277	255	277	0.97
8	17	0.034	5.8	9.5	0.7	1	14	283	296	283	300	0.88
9	17	1.1	1.9e+02	4.8	4.3	2	23	374	395	373	395	0.96
10	17	0.34	58	6.3	4.8	1	23	401	423	401	423	0.98
11	17	0.069	12	8.5	2.0	1	23	426	448	426	448	0.97
12	17	0.019	3.4	10.2	1.2	2	23	455	476	454	476	0.94
13	17	0.007	1.2	11.6	0.3	2	23	486	508	485	508	0.96
14	17	0.17	29	7.3	0.7	2	23	518	539	517	539	0.97
15	17	7.1e-06	0.0012	21.1	0.1	1	23	545	567	545	567	0.97
16	17	0.00036	0.062	15.7	0.9	1	23	573	595	573	595	0.99
17	17	3.5e-06	0.00061	22.0	0.2	1	22	601	622	601	622	0.96

Sequence Information

Coding Sequence: ATGATTTCTATTAAAAGATTTTACAATGAGTTTTGTTTTAGTATCAATAACGGAGGTGGTGAACTAGTCTCCTGTGAAAACCTCAAGCTGGAAAAGAAATCAAGAATAAAAGATGAATTTCCTATGAAAGACGATCCCGACTTCATATTTGTCCAGGAAAAAAGCCCCcgaaaaaaacgagaaaagaaGTCTGGACCGGAACTCACCCTGGAGAAATTCGTAAATCTCAACGAAGTAACCGAACCTTTATTCTGCAAAATGTGTCGTATGGTGTACAATAGCCACCTGGATTTGGGCCTGCACTCCAAAGTGCACAACGAAGACGGTTTCTTCTCCTGTCACATGTGCGATTACCGGAAAGACGTCAAGAAAACCTTCAAGATCCATATCAAGAGTCACGACCTTTTCAAATGCGAGAAATGCGGCAGAATCCTGAAGAGCAAGCTGTGCGCATACAAACACTCCAAATCACATTCCACGCAGAACACTGTCCAGTGCGAAATTTGCGGCAAACACCTCAAGAAGCAGTGTCTTCCGATCCATAAAAAAATCCTGCACTGCGACGATCGAAACGCGTTGATAACCAAATGCCCTATTTGCGGGAAGGAATACCAGAATCCCAGCAGCTTGAGACAGCACTACTCCGCTGCTCACAAAGAGTTGGGCATCGACGTTTCGGTCGTGTGTGACATCTGCGGAATGAGACTTTCTTGCAAAGGCAAGCTGCCGCAGCACTTGCGCACACACACCGGGGACAAGCCATTCGCTTGTGAGTCTTGTCCTAAGCGGTTTATAGCGAAAGACATACTTGCCGCCCATATGAGGGTTCACACGGGAGAGAAACCTTACGAGTGCAGCTTTTGCGGAAAAAAATTCGCCCACAGCGCTCCTTATAGGTCGAAGAACAGCAGAAACACGAGATCTTCTACGAAGTCATGCATCCAGAAAAAATCCACGaaggaaacaaaagaaaatgaaTCTTTCGACGTCAGCCAAGACTCAGAGTTTATTCCCGAAAAGAAGTCATCGAGCACAAAGGTGAAACATCGGAATTCAGAAGAATTACTCAAACTAATTCTAGAAAATTTCACCAGCTTAAACGAAACGAAAGCGCCTCTCGAATGTAGCCATTGCTTGAAATTATTCTCCACTCATATGGATTTCGGACTGCATTCCAAAACGCACAACAGAAAAGGTCTCTTTTCCTGTCACTTGTGCGAATATAAAAAAGATACCAAGAAAACGTTCGAGAACCACATCAGGAGTCACGATCTTTACAAATGTCAGAAGTGCAGTAAAGTAATGCGAAGCAAGCGCTGGGCTTACAAACACTTGAAAGCGCATAGTCTGACGAACAGTTTGCAGTGCGAAATCTGCGGCAAACATCTGAAGAAAGAGTCTCTCTCGACGCATCTCAAACTGATCCACGCAGAAGACAGAAGTTCTCTCATCACGAAATGCCCCATTTGTAGCAAAGAGTACCTCAACGCCGGTAGCTTGAGACAACACTACTCGAGGGCGCACAAAGAGCTAGGAATCGACATTTCTGTAGTGTGCGATATCTGTGGCTTGCGACTCTCCTGCAAGAGTAAGCTGAAGCCCCACATAATGACCCATACGGGGGATAAGCCGTTCGCTTGCGCGCTGTGTCCGAAAAAATTCGTGGTGAAGGACAAACTGAACGCACATATGAGGGTGCATACGGGAGAAAAGCCGTACGAGTGCAGATACTGCGGGAAAAAGTTCGGTCAAGATGGACCGTACCGGTACCACATCAAAACTCACACCGGTGAGAAGTCCTACAGCTGTCCTCTTTGCGGAAAACGATTCATCACCAAGGCTAACATGCGGATACATTTGAAGACCTGCAATATATCCAATAGATGA
Protein Sequence: MISIKRFYNEFCFSINNGGGELVSCENLKLEKKSRIKDEFPMKDDPDFIFVQEKSPRKKREKKSGPELTLEKFVNLNEVTEPLFCKMCRMVYNSHLDLGLHSKVHNEDGFFSCHMCDYRKDVKKTFKIHIKSHDLFKCEKCGRILKSKLCAYKHSKSHSTQNTVQCEICGKHLKKQCLPIHKKILHCDDRNALITKCPICGKEYQNPSSLRQHYSAAHKELGIDVSVVCDICGMRLSCKGKLPQHLRTHTGDKPFACESCPKRFIAKDILAAHMRVHTGEKPYECSFCGKKFAHSAPYRSKNSRNTRSSTKSCIQKKSTKETKENESFDVSQDSEFIPEKKSSSTKVKHRNSEELLKLILENFTSLNETKAPLECSHCLKLFSTHMDFGLHSKTHNRKGLFSCHLCEYKKDTKKTFENHIRSHDLYKCQKCSKVMRSKRWAYKHLKAHSLTNSLQCEICGKHLKKESLSTHLKLIHAEDRSSLITKCPICSKEYLNAGSLRQHYSRAHKELGIDISVVCDICGLRLSCKSKLKPHIMTHTGDKPFACALCPKKFVVKDKLNAHMRVHTGEKPYECRYCGKKFGQDGPYRYHIKTHTGEKSYSCPLCGKRFITKANMRIHLKTCNISNR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -