Basic Information

Gene Symbol
-
Assembly
GCA_958502065.1
Location
OY293412.1:92151358-92158332[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 7.7 1.3e+03 2.1 0.5 1 8 207 214 207 215 0.92
2 15 1.1e-05 0.002 20.4 0.3 1 23 250 272 250 272 0.97
3 15 0.26 45 6.7 4.7 1 23 360 383 360 383 0.92
4 15 0.004 0.69 12.4 5.3 1 23 393 415 393 415 0.97
5 15 4.7e-07 8.1e-05 24.8 0.4 1 23 420 442 420 442 0.98
6 15 2.2 3.9e+02 3.8 0.2 1 11 448 458 448 462 0.89
7 15 0.43 74 6.0 1.5 3 23 599 619 598 619 0.94
8 15 5.4e-05 0.0093 18.3 0.2 1 23 624 646 624 646 0.98
9 15 0.0027 0.46 13.0 1.0 1 23 650 672 650 672 0.98
10 15 0.12 20 7.8 0.5 1 23 678 700 678 700 0.93
11 15 0.00043 0.073 15.5 0.6 1 23 706 729 706 729 0.93
12 15 3.4e-05 0.0059 18.9 2.0 1 23 740 763 740 764 0.96
13 15 1e-05 0.0018 20.6 0.6 2 23 772 793 771 793 0.98
14 15 0.002 0.34 13.4 3.5 1 23 799 821 799 821 0.97
15 15 0.0084 1.4 11.4 1.4 1 23 849 871 849 871 0.97

Sequence Information

Coding Sequence
ATGGATTTTTTCACACCTATAGTAACGTTAGAAGAAGCACCTCCGAAGCCTCAAACACCAAAATCTTcgccaaaaataaaaaagataaaaattaaaattgaaggCACTGAAGAAGGGGACATTTCTGGAGAGATCGTCAAGCCAAAACGGGGTAGACCAAAGAAGATCAGTACCATAGTCAAAACTGAAAATACTGAAGAAGCCGGAAATACCGAAGAAACCGCAAATACCGAAGAAGTAGTAAAACCGAAACGAGGTAGACCCAGAAAAGCCGCCACTGGTTCAGTAGCAGATGCCAAAAAAGATATTACTAGCATAAACTTTGATAATGAAGATGACGATCCTTCGTGGTCTACAGGAGCTAATcataagaagaagaaaaagaaaaaagaaattaaaatgaaaaacaaaaaatcttctAAGAAATCATCGAAAGTAAAAAATGAAGAAGTTGTTATAAAAACAGAGCCCTTAGATGAGAATATCGCTGGGAATTTCGAAGGGGAAATCAAAAAGGAAATCAAAGAAGAACCTGCCGACTCCATTGAATTGCCCGTTATAGTTCCACTGACAGAGGAGGAATTCAAAGCAATGATGCCTCCGGAAGACCACAGAAAGTTTCGATGTCCCCTCTGTCACAAAGAAAAACAAGACGTAACAGAACGGACCCCAAAAGATCTCAAGGAACACTACAAGGACCAGCATCCCGGCAAGAGGCTAAGACAGTCTCGCTTTTCCAACGAGGTGCACCCTTGTGATATCTGCGGAAAGGAATTTCGAACAAACAGCGCTGTCAAAGACCATGTTGAAACACACAACAACTACTTCTACTGCGAAGTTTGTAACGCTTCTCAGAAAAAAATCCTTGATCACATTATACATTTGAGGATACACTCGGAACCAGGCATATTCCAGTGTCTGATGTGTGAACTCAACACTCCTGATATCAACAAGATTACGGAGCACGTAAACAACCATGAAGATTTGTTGAAGTATTGGTGTCAACCCTGCAAAAAGGGGTTTCAGGTCTTGCCGTGGTTTCAAGAGCACGATAACTACCATACAGGATTGAAACCGTTCGACTGCGAGTTTTGCGGAAAATGTTTCTTGTATTCGCGCTATCTCCATGCCCACAAGATAAACATGCACAAGGAAGATATGAACTTCCCGACCTTGCATGAGTGTGTCATATGCAAGAAGCAGTACCAGCACAAAAACAGCTTGAAGTTGCATATGAACTCCCACACGGAACGACCTTATATATGCGATTACTGTACGAAAGCATTCTCTCAAAGGTCTAGTCTTGTCATACATATGAGGGGACATACGGGCGAAAGGCCTTATGTCTGCCAATTTTGTACTAAAGCCTTCGTTGCTAAAGCAATGACCTACCAGTTAAACGATAATGTTTGGGAAGAAATTGTGATATCTATTGTTGACGAAGATTCGGACGAATGTACGCTTGAATATTCAGATGACTCTAAACCCATGGACATAAATGATTTCATAAATAATCTGAACACTGCAATAAAAAATGAACCGCCAGATCAGGATAATCTGTTCATAGAAAcacttgaaacaaaaaataatccctCTTCAACAGATCTTCTATACATAAATGGTACACTTATGGACACAATCGACGACCACTATATGACCGAACCTGAGTCCGATAGATCTGATCgaagaaggaaaaaaaaaactattttccacGACAGCTTATGCGCCGTCTGTGGTAAAATAGTGAAGGGTAAGAATATGCCCAAGCACATTGCCAGTCACAGCGATGAACATTGTGACATTTGCATGGCGTCATTCAAATCAACCAAAGAACTGGAAAGTCATAAAGAATTGCACTTGGAAAACGATTATCCTTGTGACGTTTGTGGCCtgagtttcaaaaatgctagAGATTTTGCTCTTCACACAAACAAACATTCCGGAGAATATTCCTGTCCAATGTGTAACTTCAACACGAAGAGCAAAAGCTCTGTGATGGGACATATCAAGAGGCACGAAGGAAAGTTTACCCACCATTGCGCCATCTGCGGAAAGGGTTTTCTGGGTAAAGCACTACTGATGACTCATGAGGAAATTCACCTGGACATCAAACGATATGCGTGCGATATTTGTGATAAAAAATTCTCTGTCAAAAGGTACTTGGATGTCCATCGCTCACTCAACCACAAGAAGGAACTGTTTGGTATCGATCAGCTCTATAAGTGTGGTCTTTGTGGAAGGGAATTCACATTCGAGAAAAGCCTGCGTCGTCATCAAAGCGTCATACATCACATTGGGGAAGATCTCACCGTCCAATGCGAAGTATGCCACAAAGTGATCGCCAACAGTTATAACCTTAAAATGCATATGCGCATTCACACTGGTGAGAAGAATTTCTGCTGTGATACGTGTGGGAAAGCCTTTTCGGGCTATAAGTATTGGAAAAAACATCGAGTGACGCATGACAGGCAGAAACCAGATGAAAGAAATAATAAGAATGCCGAAAGTGAGCCAAGCCGGAATAGATTCCCTAGATCGAGGAACTATTGCTGTGAATTTTGTGATGAAGAATTTTCTTCTATAAAAGCTTGGAAAAAACACGAATTAATGCATGTATCGTTAAATGATGAAGCcactgaagaagaaaaaaatatgattgaaatCGAAGATATTGAGTTTGGGTTTAGTGATGAAATGCTTCCATATGGGATCAACTGA
Protein Sequence
MDFFTPIVTLEEAPPKPQTPKSSPKIKKIKIKIEGTEEGDISGEIVKPKRGRPKKISTIVKTENTEEAGNTEETANTEEVVKPKRGRPRKAATGSVADAKKDITSINFDNEDDDPSWSTGANHKKKKKKKEIKMKNKKSSKKSSKVKNEEVVIKTEPLDENIAGNFEGEIKKEIKEEPADSIELPVIVPLTEEEFKAMMPPEDHRKFRCPLCHKEKQDVTERTPKDLKEHYKDQHPGKRLRQSRFSNEVHPCDICGKEFRTNSAVKDHVETHNNYFYCEVCNASQKKILDHIIHLRIHSEPGIFQCLMCELNTPDINKITEHVNNHEDLLKYWCQPCKKGFQVLPWFQEHDNYHTGLKPFDCEFCGKCFLYSRYLHAHKINMHKEDMNFPTLHECVICKKQYQHKNSLKLHMNSHTERPYICDYCTKAFSQRSSLVIHMRGHTGERPYVCQFCTKAFVAKAMTYQLNDNVWEEIVISIVDEDSDECTLEYSDDSKPMDINDFINNLNTAIKNEPPDQDNLFIETLETKNNPSSTDLLYINGTLMDTIDDHYMTEPESDRSDRRRKKKTIFHDSLCAVCGKIVKGKNMPKHIASHSDEHCDICMASFKSTKELESHKELHLENDYPCDVCGLSFKNARDFALHTNKHSGEYSCPMCNFNTKSKSSVMGHIKRHEGKFTHHCAICGKGFLGKALLMTHEEIHLDIKRYACDICDKKFSVKRYLDVHRSLNHKKELFGIDQLYKCGLCGREFTFEKSLRRHQSVIHHIGEDLTVQCEVCHKVIANSYNLKMHMRIHTGEKNFCCDTCGKAFSGYKYWKKHRVTHDRQKPDERNNKNAESEPSRNRFPRSRNYCCEFCDEEFSSIKAWKKHELMHVSLNDEATEEEKNMIEIEDIEFGFSDEMLPYGIN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-