Came012637.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Chrysolina americana
Gene Symbol
mecom-b
Assembly
GCA_958502065.1
Location
OY293411.1:73170273-73211979[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.13 23 7.6 0.1 2 23 179 201 178 201 0.95
2 10 0.001 0.17 14.3 3.1 1 23 208 231 208 231 0.96
3 10 0.95 1.6e+02 4.9 0.2 1 14 237 250 237 251 0.88
4 10 0.0013 0.22 14.0 0.1 9 23 276 291 275 291 0.96
5 10 1.9e-06 0.00033 22.8 1.7 1 23 297 319 297 319 0.95
6 10 4.8e-05 0.0083 18.4 5.0 1 23 325 347 325 347 0.99
7 10 0.00096 0.17 14.4 0.7 2 21 355 374 354 375 0.95
8 10 1.6e-08 2.8e-06 29.4 0.7 1 23 697 719 697 719 0.98
9 10 2.1e-06 0.00037 22.7 1.6 1 23 725 748 725 748 0.97
10 10 4.9e-06 0.00084 21.6 3.4 1 23 754 776 754 776 0.99

Sequence Information

Coding Sequence
ATGAAAGGATCCGATCTTAGCTCTCATATCGTAGACAAGAAACAGGTAGTTGCTGGTTCTGGCGTTCGAGGCTGGCTGGATGGTTCTGTGGAACATCAAAATTGGTTGAAGCTCATCCAGAGCGCTCCCGACAAATCAGACGCAAATCTCAGATATAATTTGCAAGGAGGTCAGCTATGGTACGAAACGTTTCAAGAGATACCGACAGGCACCGAGTTGACATTGGCACAGAGAGAACCTCTGAATCTTCAGGATATGTTTGGGGATTCAGCCGATGAAAGATCCGATAGAGAAACagATGATTTCATATCAATGACAGGACAACGAGTAGCTGAACCGGATATTGCAAATGAAGAGCAAACAGAGAACAAAAAAAGAGATAATAATTCACAAAACATAAGAACTAGGTGCCAAGAGAAATATACGTACAGAGAAGTCAAAGCTAAAACATTTGATGATAGTGCTAAACATAAAGCCTCTCAACACAGTGGAACTCTAGACGAGCGCGAAGAAGACGACGAAGATTCCGAAATCAGATGCTACGTCTGCGATCAGGCATACAACGATATCGACAAGTTAGATGAGCATCTCATATCAAAACACAACTATCGAAGAGACGAGTATCAATGCGAGTTCTGTCCCAAAGCATATTCACATCGTCCTTGTTTGATCAAACATCGAGCCGTCAAACACGGAGAAACAAAGAAATATCATTGTGAAAACTGCCCAAAGTCCCTGAGCTCCCCAGAAGATCATCACAGCATATTAAAGACCCCGCAGCCATATAATGGAAGAGTGATTAAATCAAATGCTGCTGAATTTCCGGTTTTCACAGATCCAAGCAATCTCCAAAGGCATATAAGAACAAATCATGTGGGTGCAAGGTCTCATGCTTGTCCCGAATGCGGAAAAACATTTGCAACATCCTCTGGTTTGAAACAGCATACTCATATCCATTCCTCTGTGAAACCTTTTCAATGTGAGGTGTGCTTCAAGgcGTACACACAGTTTTCCAACCTTTGCCGTCACAAACGAATGCATGCCGATTGCCGAATGCAAATAAAGTGCGTCAAGTGTGGACAGTCCTTCTCCACTGTTACTTCCTTATCGAAACACAAACGATTTTGCGATTCTACGGCGCCCACGTCTTCTCTAGCATCACAACCTCAATTACCTCTGAGTGCAATGGCTGGGACCAATCCATTTCCACTATATAGGTCACCAGGATGTCCTCTACCATTTGGATTTCCCCCCCAGTTTCCATCTTACCATCAACTGTTTCCTTCTGGTCCGATGATTCCACCcctatttttcaatcaaatgcatAAGTTGAACTCTGGGGAGGACCACTCCCCACCTAAGAAACTAAGGTTGAGTAACGAAGGTATGTCCCCGAAAGTGGAGAGATTTTCGCCAAAAATGGAAAGAGTTTCACCCAACGTTGAGAGATTCACGCCACCAAGAGAAACAACCTTTATGGCAAAAATTAGTCCACCCAAAGGCGCCGAAGCCAATGTAGCTCCTTCACCAGCAAGACCTAACAAAGTATTTACACGAACTGACCATATTAGAGTGGAAATACCTGAAGAAGAAGATGATTTTCCTAGGGACTTGTCAAAGAACTCATGTAGTCCGGCATCTTCAAGTAGTGATGGAGATCAACCGTTAGACTTGAGCGGAtggaaaaaatctaaatttgttCCAGATACAAAATCTGTTGAATTGCAACGACAGACTCCCAAGTCACCAGATCCCACGAGAGAAGAAAGAATTGAAGTCGTGGAGGTAGAGGAGGACAAGTCACTGAACATGGATAAAACCCCTATTAAACCAACAATGGCATATCCGCGACCGATACATCCAATGATGCCTGAGTTAGGTAGAACATTTCCCTATAACTACCCACACCCTCAGAGCAATGAGAGATTTCTGACCTATCCTTTCCACCACCAAAGATTTCCTTTCTTGAATACCCTACCACCTCAGAGAATGGACTTGTTCAGACCTACCTTACAGGGATTCAATAACGGTAGGCCTTTTCATGAAGTTATGCAACAGCAGGGGCAAGGCAAGGTCAATAAAGACAGGTATGCTTGCAAGTTTTGCGGAAAAGTTTTTCCTAGGTCCGCTAACCTAACTAGGCATTTGAGGACACATACAGGAGAACAACCTTATAAGTGCAGGTACTGCGAGAGATCCTTCAGTATATCTAGTAACCTTCAGAGACACGtcagaaatattcacaataAAGAAAAACCATTCAAGTGCCCCCTTTGTGACAGATGTTTTGGTCAACAGACCAATTTAGACAGGCACTTGAAGAAACATGAATCTGACGATGGTAACGGAGGAGTAGCTGTAGCAGATTCACCAGGAAGTAGTAACGAAAATGAGAGAGAAGATGCCTGCTTTGATGATATCAGAACTTTTATGGGAATAGTGACGTCTGGTAGCGCAGAATACTATAATAATAGCAGGAGTTACAATACCTCACCTTCAAATAATGATATCGATGTTGTTGGTAAAGAAGATGAGGATTCGGAAACATACTCAGAGGTTGCTGAAGATTATTTGCCACAAAAGTCGAATTTTGAGCAATCCATGAAACAAGAGAAGGAAACATTGCTGAATAATAATGACCAGACCATCGAGGTTTCTACTTAG
Protein Sequence
MKGSDLSSHIVDKKQVVAGSGVRGWLDGSVEHQNWLKLIQSAPDKSDANLRYNLQGGQLWYETFQEIPTGTELTLAQREPLNLQDMFGDSADERSDRETDDFISMTGQRVAEPDIANEEQTENKKRDNNSQNIRTRCQEKYTYREVKAKTFDDSAKHKASQHSGTLDEREEDDEDSEIRCYVCDQAYNDIDKLDEHLISKHNYRRDEYQCEFCPKAYSHRPCLIKHRAVKHGETKKYHCENCPKSLSSPEDHHSILKTPQPYNGRVIKSNAAEFPVFTDPSNLQRHIRTNHVGARSHACPECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHKRMHADCRMQIKCVKCGQSFSTVTSLSKHKRFCDSTAPTSSLASQPQLPLSAMAGTNPFPLYRSPGCPLPFGFPPQFPSYHQLFPSGPMIPPLFFNQMHKLNSGEDHSPPKKLRLSNEGMSPKVERFSPKMERVSPNVERFTPPRETTFMAKISPPKGAEANVAPSPARPNKVFTRTDHIRVEIPEEEDDFPRDLSKNSCSPASSSSDGDQPLDLSGWKKSKFVPDTKSVELQRQTPKSPDPTREERIEVVEVEEDKSLNMDKTPIKPTMAYPRPIHPMMPELGRTFPYNYPHPQSNERFLTYPFHHQRFPFLNTLPPQRMDLFRPTLQGFNNGRPFHEVMQQQGQGKVNKDRYACKFCGKVFPRSANLTRHLRTHTGEQPYKCRYCERSFSISSNLQRHVRNIHNKEKPFKCPLCDRCFGQQTNLDRHLKKHESDDGNGGVAVADSPGSSNENEREDACFDDIRTFMGIVTSGSAEYYNNSRSYNTSPSNNDIDVVGKEDEDSETYSEVAEDYLPQKSNFEQSMKQEKETLLNNNDQTIEVST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00329906;
90% Identity
iTF_00329906;
80% Identity
-