Came021414.1
Basic Information
- Insect
- Chrysolina americana
- Gene Symbol
- Zfx
- Assembly
- GCA_958502065.1
- Location
- OY293412.1:92067051-92076302[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 26 0.71 1.2e+02 5.3 0.8 2 23 33 54 32 54 0.94 2 26 4.1 7e+02 2.9 1.5 1 23 60 82 60 82 0.91 3 26 8.6e-06 0.0015 20.8 3.9 1 23 116 139 116 139 0.97 4 26 0.015 2.5 10.6 6.3 1 23 151 173 151 174 0.94 5 26 2.6e-05 0.0044 19.3 0.7 3 23 185 205 184 205 0.99 6 26 8.6e-05 0.015 17.7 3.2 1 23 211 233 211 233 0.97 7 26 0.00084 0.15 14.5 2.2 2 23 240 261 239 261 0.96 8 26 0.00027 0.047 16.1 0.3 3 22 269 288 267 288 0.90 9 26 1.1 1.9e+02 4.8 1.8 2 16 354 368 353 375 0.80 10 26 0.013 2.3 10.8 1.6 1 23 381 403 381 403 0.98 11 26 0.14 24 7.6 4.7 1 23 409 431 409 431 0.91 12 26 4.1e-05 0.0071 18.7 2.4 1 23 437 460 437 460 0.97 13 26 0.0038 0.65 12.5 4.4 1 23 472 495 472 495 0.96 14 26 0.00014 0.024 17.0 0.2 2 23 505 526 504 526 0.97 15 26 1.5e-05 0.0026 20.0 1.5 1 23 532 554 532 554 0.97 16 26 0.00017 0.029 16.7 1.1 1 23 560 582 560 582 0.98 17 26 0.00037 0.063 15.7 0.4 1 21 588 608 588 609 0.95 18 26 0.05 8.6 9.0 0.7 2 23 656 677 655 677 0.96 19 26 0.074 13 8.4 2.1 1 23 683 705 683 705 0.97 20 26 0.054 9.3 8.9 2.6 1 23 708 730 708 730 0.91 21 26 0.00014 0.024 17.0 2.6 1 23 736 759 736 760 0.97 22 26 0.00084 0.15 14.5 2.0 1 23 771 794 771 794 0.95 23 26 1.6e-05 0.0027 20.0 0.7 3 23 805 825 803 825 0.97 24 26 5e-05 0.0087 18.4 1.9 1 23 831 853 831 853 0.98 25 26 0.0018 0.32 13.5 1.8 1 23 859 881 859 881 0.98 26 26 1.2e-05 0.0021 20.3 0.3 1 21 887 907 887 908 0.93
Sequence Information
- Coding Sequence
- ATGAGAAAGTGTGAAACGAAAGCAGTGGCAAAAcctaaaaagaaaaagaaacctTTACTAATAATTGTTGAACCTACGGATTTCGATATACCTCTCAAGTGTGACTTATGTCAGTCGACATACAAAAACAACCTAGACTTTGCCCTCCATTCGAAAGAACACAGCGACAATGGAACATTTTCCTGCCACATATGCACTTATAAAAACTCCTTGAAACCGCTCTTCGAGCTCCACGTAAGAGCACACGAAGGCATCAACAAGTACAAGTGCCAAACCTGCTGCAAAACGTTCAAAAGAACCGTTGATGCAGACGAGCACAAGTATTTTCATACAGGAGAGAAGCCATTCCAATGCGAAATCTGCGGGAAGCACTTCAGCTATTCCAGAACGCTGACTACACACCGACGCCTCACACACTACGAGGTGGTAACAGGGCAGAAACTGGTAAAATTCGACTGCACTATCTGCAACAAGCACTACGCCACCCACTCTGGTCTTTATAGGCACAACTCGATGCACCACAAGGAACTGGGCTTCGATTGGTCCGTGTTGTGCGACATCTGCGGCAAAAGTATCGCCACGAAGAACAAGCTCAAGTACCACATGCGCACGCATACCGGTGACCGGCCGCATGTCTGCCACGTATGTTCGAAGGGATTCGCCAAAAAGGAACAGCTCAAAACTCACGAAAGGGTGCACACCGGGGAAAAACCTCTCAGCTGTGACCACTGCGGTAAGAGGTTCGCGCATTTGGCACCCTTCAACTATCATTTGAAGATCCACTCGGGAGAGCGTTCCCATGCTTGTATAATTTGCGGGAAGACTTTCATTTCGTTGAGTAATATGAAGATCCACATGAAGACCTGCGATCGAGGAAAGATATCTGTTGTCCCTGAGAAcaagaaaacaaaaagaaagTACGTCAAGAAAAAGCTTAAAGAACCTAGAAACGGAAAAGAAGAAAAAGCAAAACCCGCCAAAAGAGATCGAAAACCAAGAATAAAGTCCGAGAAACCCCCCAAAATCATAGCCAAACCCGTAGATCTAGAAGAACCTCTCAAATGCAAACACTGCAACGCAGAGTTCAAGAACAACCTCGACTTCGCATTCCACTCGAAAGACCACAGCATCGAGGGAGAATTCTCTTGTCACATTTGCGACTACAAAAGTACTTCGAAGCCGCCATTCGATCTGCACATGCGCGAACACGAGGGCATCAACAAGTACAAGTGTCCGTGCTGCGACAAAACGTTCAAGCAGAGCAAGGATGCCATGGAACACAAATATTTCCACTCGGGCGAAAAGCCCTTCCAGTGCGAAATATGCGGGAAGCATTTCCCGTACACCAAAAGCCTCTCCGCTCACAGGCGCAATACTCACTACGAAATAATCACGGGCAAGCCCTTGCAGAAATACGACTGCAAGATCTGCAAGAAGCACTACGAGAGCCATTCAGGTTTGGTCAGGCACTACTCTTCTAGTCACAAAGAACTCGGGTACGACTATTCCGTCGTGTGTGATATATGCGGAAAGACCATAGCCACGAGGAACAAGCTCAAGTACCATCTGCGGGTGCACTCGGGATACAAGCCGCACGTCTGCAGCATTTGTAACAAGGGCTTCTCGAAAAAGCAGGAACTGAAGATTCACGAACGGGTGCATACTGGAGAGAAACCGTTCTCCTGCTCGTTTTGCGGAAAGAAATTCGCCCAGCTAGCGCCTTATCGGTACCATATCAAAACGCACACCGGAGAAAGAACCCATGTGTGTATGATATGCAAGAAAGGTTTCATTTCGTTGAGCAACATGAAGATTCACATGAAAAATTGCGATCAAATCATCAAGTGTGAGCCAAAGAAATCCGGAAAGAAATTGAAGAGCGTGACAGTCAAGCCTCCTGTGGAACCTCAAATCGACGAAGAATCCACCAATCTCATCATCCTCCTGAAAGTCGACAAACTCCTAGTCTGTGGAAAATGCTCCAAAGGTTTTCCTGACCACCTCGAATTGGCTTATCATTCCAAAAAACACAGCGATTCAAGAGAATACTCCTGCCACATATGCCCCTTCAACGTAAACTCGAAATTCCGCATCCGACGGCACATAAAAGCCCATGCGGGTTACAAATGCCGATTGTGCAACAAGGTTTTTAAACGGGGACGCACAGCTCTCAAGCATTCCTACCGCCACAGCGGCGAAAAGCCCTACAGATGCAACATCTGCGACAAAAAACTGGCAAATCCAAAGAGCTTGGATACGCACATGCACACCATACACCATGAACTGCTAACGGGCAAGCCTCTGAGCAAATTCGACTGTCCCATCTGCAAGAAACACTACGAGTCGGAGACGGGTCTGAGAAGACACTACTCCAGCACACACAAAGAGATGGGCGTTGACTTGACAGTGATTTGTGAGGTGTGCGGGAAGAGAATTTCCAACAGAACGAGGCTGACGCGCCATATGCGCACCCACACCGGACAAAAACCTTTCCCTTGCAGCATTTGCAATAAGagtttcgccacaaaatgcctCATGATCTCCCACACGAGAATCCACACCGGCGAAAAACCGTTCGAATGCTCGTTCTGTGGTAAGAGGTTCGGCCATTCGGCACCGTATCGGTACCACGTAAAAATCCATACAGGAGATCGGAAATACCTCTGCAAGCTTTGTGGAAAAAGTTTCATTTCTGGCAGTAACTTGAAGATTCATATGAAGAGTTGTTATATACCCATGAAAGGGGAGAGAGTTTGA
- Protein Sequence
- MRKCETKAVAKPKKKKKPLLIIVEPTDFDIPLKCDLCQSTYKNNLDFALHSKEHSDNGTFSCHICTYKNSLKPLFELHVRAHEGINKYKCQTCCKTFKRTVDADEHKYFHTGEKPFQCEICGKHFSYSRTLTTHRRLTHYEVVTGQKLVKFDCTICNKHYATHSGLYRHNSMHHKELGFDWSVLCDICGKSIATKNKLKYHMRTHTGDRPHVCHVCSKGFAKKEQLKTHERVHTGEKPLSCDHCGKRFAHLAPFNYHLKIHSGERSHACIICGKTFISLSNMKIHMKTCDRGKISVVPENKKTKRKYVKKKLKEPRNGKEEKAKPAKRDRKPRIKSEKPPKIIAKPVDLEEPLKCKHCNAEFKNNLDFAFHSKDHSIEGEFSCHICDYKSTSKPPFDLHMREHEGINKYKCPCCDKTFKQSKDAMEHKYFHSGEKPFQCEICGKHFPYTKSLSAHRRNTHYEIITGKPLQKYDCKICKKHYESHSGLVRHYSSSHKELGYDYSVVCDICGKTIATRNKLKYHLRVHSGYKPHVCSICNKGFSKKQELKIHERVHTGEKPFSCSFCGKKFAQLAPYRYHIKTHTGERTHVCMICKKGFISLSNMKIHMKNCDQIIKCEPKKSGKKLKSVTVKPPVEPQIDEESTNLIILLKVDKLLVCGKCSKGFPDHLELAYHSKKHSDSREYSCHICPFNVNSKFRIRRHIKAHAGYKCRLCNKVFKRGRTALKHSYRHSGEKPYRCNICDKKLANPKSLDTHMHTIHHELLTGKPLSKFDCPICKKHYESETGLRRHYSSTHKEMGVDLTVICEVCGKRISNRTRLTRHMRTHTGQKPFPCSICNKSFATKCLMISHTRIHTGEKPFECSFCGKRFGHSAPYRYHVKIHTGDRKYLCKLCGKSFISGSNLKIHMKSCYIPMKGERV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -