Came021396.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Chrysolina americana
Gene Symbol
zfh1
Assembly
GCA_958502065.1
Location
OY293412.1:91942818-91964277[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 39 1.4e-06 0.00024 23.3 1.3 1 23 42 64 42 64 0.98
2 39 0.0017 0.3 13.5 4.8 1 23 69 92 69 92 0.92
3 39 1.6 2.8e+02 4.2 3.8 2 23 99 121 96 121 0.86
4 39 0.00062 0.11 14.9 1.7 1 23 127 150 127 150 0.93
5 39 7.4e-05 0.013 17.9 3.4 1 23 155 177 155 177 0.99
6 39 0.023 3.9 10.0 2.3 1 23 186 207 186 207 0.95
7 39 7.9e-06 0.0014 20.9 0.4 2 23 216 237 215 237 0.97
8 39 7.7e-06 0.0013 21.0 0.6 1 23 243 265 243 265 0.99
9 39 6e-06 0.001 21.3 0.2 1 23 271 293 271 293 0.98
10 39 0.37 63 6.2 8.2 1 20 299 318 299 320 0.92
11 39 0.0015 0.26 13.8 1.2 2 23 336 357 335 357 0.97
12 39 0.045 7.7 9.1 1.5 2 23 363 385 362 385 0.96
13 39 0.0011 0.2 14.1 5.6 2 23 392 414 391 414 0.95
14 39 0.0075 1.3 11.5 4.3 1 23 420 443 420 443 0.95
15 39 0.00065 0.11 14.9 2.5 1 23 448 470 448 470 0.98
16 39 0.0039 0.68 12.4 4.9 1 23 479 501 479 501 0.98
17 39 0.00055 0.095 15.1 1.4 1 23 508 530 508 530 0.97
18 39 2.8e-05 0.0049 19.2 1.5 1 23 536 558 536 558 0.98
19 39 8.9e-07 0.00015 23.9 0.2 1 23 564 586 564 586 0.98
20 39 0.62 1.1e+02 5.5 0.3 1 14 592 605 592 608 0.89
21 39 0.034 5.9 9.5 2.4 1 21 611 631 611 632 0.94
22 39 8.5 1.5e+03 1.9 0.1 2 23 641 662 640 662 0.88
23 39 0.0008 0.14 14.6 1.6 1 23 668 691 668 691 0.92
24 39 0.009 1.5 11.3 0.4 2 23 698 720 697 720 0.93
25 39 0.049 8.4 9.0 4.0 1 23 725 747 725 747 0.96
26 39 7.6e-05 0.013 17.8 5.8 1 23 756 778 756 778 0.99
27 39 8.2e-06 0.0014 20.9 0.2 1 23 785 807 785 807 0.98
28 39 0.00086 0.15 14.5 4.5 1 23 813 835 813 835 0.97
29 39 1.4e-06 0.00025 23.3 0.6 1 23 841 863 841 863 0.98
30 39 0.29 51 6.5 0.3 1 14 869 882 869 885 0.88
31 39 0.00015 0.026 16.9 4.9 1 23 894 916 894 916 0.98
32 39 0.97 1.7e+02 4.9 0.0 1 23 931 954 931 954 0.92
33 39 0.003 0.52 12.8 4.5 1 23 960 983 960 983 0.95
34 39 0.00062 0.11 15.0 0.5 2 23 989 1011 989 1011 0.90
35 39 0.0018 0.31 13.5 1.2 2 23 1019 1040 1018 1040 0.97
36 39 0.00072 0.13 14.7 0.5 1 23 1047 1070 1047 1070 0.97
37 39 3.3e-05 0.0057 19.0 0.6 1 23 1076 1098 1076 1098 0.98
38 39 1e-05 0.0018 20.6 1.2 1 23 1103 1126 1103 1126 0.98
39 39 0.013 2.2 10.8 1.8 1 20 1132 1151 1132 1153 0.95

Sequence Information

Coding Sequence
ATGATTAAAATAATGATAAGTTGTGTTGACACATCTCCGAACCGATCAGAAGGCAGTAGGTTGAAAGGAAAGCTCGCCATCGACTATTCTGCTGTTTTCCATTGCGAAGTAGATTATAGGGAATACAACTGCGATAGTTGCCCCAAAACGTTCGCTTCCTTGTCGAATTTGAGGCGACACAGAAACACTCACCGAGAAAAAATGTTCGCCTGTGATATGTGCAACAAGTCCTTCCACCAAAAATACAACCTCGAATATCACAAGAACTTCAAACACTTCAGGAAATTCACGTGCAAGTGCTACTACTGCGACCAAGTGTGTTTGAACAAAAACGGGCTCAAGCTGCACATCGACAACGTGCACTTGAACAAGTACAAATTCTGCTGCGACCAGTGCCCGAAGGGCTATAATTCGAAAAGCGAGCTCGCCAAGCACGTCCAGTTCGACCACGAAGGGCTCCGATACACGTGCTTGGTGTGCGAAAAGGAGTTCAAGGACAACAACCACTTCAAGCTCCACATCAAAACCCACGACCCGAATTACAGCAAGCCGGAGTTTACGTGCAAGATTTGCCAAAAGGTGCTGTCCACGAAGTCTTTCGACAGGCACATGAAGATGCACGCGGGAGACACCGACAACAACGTTGTGTGCGACATTTGCGGCTTGGTCGTTTCGAGCAAGAGCCACCTCATCAACCATCGGCGCACGCATACAGGGGAAAAACCGTACGAATGCGACTTCTGTGATAAACGATTCGCGAGGAACGAGACCTTGGTGGATCACAGGAGGGTGCATACGAAAGAGCGGCCGTATATTTGCTCGGTGTGTTCGAAGGGGTTCACGCAAAAGTCCGCTTTGAACGTTCACGCGCGGATCCACACCGGTGAAAAACCGCACGATTGTATGTTCTGCACAAAGAAGTTCAGTACGAAACATTTGCTTAAACATCACAAGTGCGCTAGAACCGGTTATCATGCCGTAATGCCCGCTACCGATCAATTCATTCAATGTAAAGTATGCCAGAAGAAGTTCGACAGCTTGGGAAAACTAGGAAGACACTCGAAAACTCACACAGAAAAATCTCTCACGTGTGAATTATGCCATAAAAAGTTCAAGTGGCCAACGAGCTTGGGCATGCACATAAAAAAAGACCACCTGAATGATTTTTCGTGCCAGTGTCAAATCTGCGATAAAAAATTCATGCACACTACCCAACTAAAAAGCCACATGGAGAAGGTGCACATGCAGATATACAAATTCAGTTGCCAGAAGTGCACCAAAGGCTTCAGGTATCAGTTCGAATATGACAAACATATGAAATTCCAACACGAAGGGCTGAGGTTTCGCTGTGCGCACTGCCAGAAGGAGTTCAAGGACGAACCTTACTTTCGGGAGCACTTGAAAATCCACGATCCGAACTACGAAAAGACCTCTTACTCCTGTCCCTACTGTGGCAACATCTACCACCACTACAACTCCTACACTAGACACATGAAAATCCACACCGGCGAGCAAAGGGAGCACATTTGCGATATTTGCGGGAAAATTCTGTGCTCCGGTCCTAGCTTGAAGATGCACATGAGAACCCACACGGGGGAGAAACCCCACAAATGTGTAATTTGCGGGAAGGGATTCGCCAACGCTGCGACTTTACACATTCACAAACGGACGCACACTAAAGAGAAACCTTACGTTTGTAACGTTTGTCAGAAGGCTTTCAGTCAAAAACCCGCGTTGAACGTTCACATGAAGTCGCATACCGGCGAAAAACCCCATGTTTGTGTTGTTTGTAATAAAAAGTTCATTACTAAGAAAGCCCAAAACGAAGTTTTCAGCTGCCCTACTTGTCCAAAAGTATACGGCTTTGAAAATCAGTTGCGCAACCATAGATGTCACAGGCAAAAAAGAAAGAGGCTGGTAACGTGCGAAATCTGCAACATTACGGTCATCGCGCAAAATCTCCGAGGTCATATCGATCGAAAGCACTTGAACGAATACGCGTTCTCGTGCAAACTATGCGACCGAAAGTTCAGGCACGCCATTTATCTGAAAGTACACGTGGATAACATTCACCTCAACAGATATAAGATATACTGCGAGGTCTGTAACAGAGGTTTCAACTTCCCAAACGAGTTGGATAAGCACCGAAAATTCGAACACGAAGGTGCTAGGTACTTCTGCAAGAAATGCCCGAGGATATTCAAAGACTGTAGGCGATTTAAGATTCACGTGGCTTCCCACGATCCGGACTATGTGGAGCCTGTCTACGAATGTACAGAGTGCGAGCAGAGGTTCAAGCAAAAGCATTCGTACAACAAGCATTTGAGGAAACACGGCGGCGAGAAGTTTGAGTACGTTTGCGAAACCTGTGGTAGAGTCACCACCACCCAAACTAGCTTGAGAGAGCACATGCTCATCCACACAGGGGAAAAACCGCATGAATGCGAGGTTTGTGGTAAGAGCTTCAACAAAAAGTGTCTGCTGGTGACGCACTTCAGACTGCACACCAATGAGAAGCCGTATGAGTGTACCGTTTGCGAGAAGACTTTCACGCAGAAGCCGGCATTGAACGTGCATATGAAATATCATACGGGTAAAAATTTGCACGAGTGTCAAGTTTGCGGAAAGAAATATGTGACTAAGCAAGGCGTCAAACTCGAACGTGATCACAACAAAGTGTACCGCTGTGAAAACTGCGGCAAGGAATGCTCCAGCTGGCACCAACTGAAAACCCACTTTCGGGGCCACGAAACCTCCACCAAGCGCCAAATCGCCATAAAACTCGAAGAATTCAGATGCGAGTTCTGCGCCAAGCTACTTGGAGATAAGGGCACGCTCGCAAGGCACGTCGCCGAAGCCCACCACCGAGAGACGCGATTCAACTGTTACAACTGCGACCAGAAATTCTACCACAAGTACATGCTGGTGCGGCATATCAAGGAGAAGCACACGGGCAGGCCTCCCACGTGCGACATCTGCGGACTGGAGTTCTCCACGTACGCGACGTTGCGTAGACACACCACCGACAAACATAACGTCGACTACCGCGATTTGTATTGTTACGAATGCAAAAAGTCCTTCGTCGGGGGCATCAGCTACAGGAAGCACATGAGGAAGCACACCGACGACGGGGCCAAGTTCGTGTGTACGGTTTGCGGCAAGATTCTGTCCTCGATGTCCAGCATGAGGGATCACATGACGCGACGCCACAGCGAGGAAACGCCGTACGAGTGCGATCAGTGCGAGAAGGCGTTCACCACCCCTTTGTCTTTGAAAAGTCACAAACTAACTCACGTCGGTCCGTCCTTCAAGTGTGAGCTCTGCCACAAGCAGTTCATCCAGCCAGCCTCGTTGAGGATCCACATAAAGAGGGTGCACGTTAAAGTGCGACCCCATCAGTGCGACATTTGTATGAAGTTTTTCGCGACAAGGACGGAGTTGAACAAACACCACGTGAGGTGTAAAGGGCCGAAGCAAGAAAAAGAATTGAAGTCTGAAACTATTCTCGCGGTTGGTCCTAACACGGTGGTTACGAGTGATGAAATAAATCAACCTACTAGTGGTAACACTGCACCTTTAGAAACTAATAACGATGACAATCATGAAGAGCAGAACTCACCAACTCCACGTCCTACGCCTTTGCAAAATAATACCAACAACAAAGATGGCATTAACACTCCCATTCGACGTCAGAAGAAAACCGTGCAAAAGATAACATCCTACGAAAGCTCGTTATTAAACATACTACAACAAAAACAACACGAAGAAATTAACGAGGAGAAACAGTTTGCTATGATGCTTGTCCCCATGTTACAGAAACTGAACAACGATCAAAAACATTATGCTCAAATAGATATCCTAAATGTAACGAGATATGCCAGAAATTTCCATCCTACGCCATTCGTTCAATATCCTCACACACATCGTAGTAACATGGTTCCATCAACTTCATTGGGCCACGCTACTGCCTACCAGTTGCCTTCGCAAGTTCCATCCTCAAACTTCCAAATGGAGCCACCCGGACATCTGCAAACAGTTTCCCAGTATTCCCTGACTAATAACCAACGTCAGAATTCTGCAGGTTCCGTGAGGACTTACTTGTCAGAATTTTCAGAAGGTTTACTATCCCCCACAGCGGGTTCCTCATCATGTGACTACTCTATGGCATCATCGATAATACCCAGTTATTTGACATGTCGAATCAATAATTATGTGGTCCATTGA
Protein Sequence
MIKIMISCVDTSPNRSEGSRLKGKLAIDYSAVFHCEVDYREYNCDSCPKTFASLSNLRRHRNTHREKMFACDMCNKSFHQKYNLEYHKNFKHFRKFTCKCYYCDQVCLNKNGLKLHIDNVHLNKYKFCCDQCPKGYNSKSELAKHVQFDHEGLRYTCLVCEKEFKDNNHFKLHIKTHDPNYSKPEFTCKICQKVLSTKSFDRHMKMHAGDTDNNVVCDICGLVVSSKSHLINHRRTHTGEKPYECDFCDKRFARNETLVDHRRVHTKERPYICSVCSKGFTQKSALNVHARIHTGEKPHDCMFCTKKFSTKHLLKHHKCARTGYHAVMPATDQFIQCKVCQKKFDSLGKLGRHSKTHTEKSLTCELCHKKFKWPTSLGMHIKKDHLNDFSCQCQICDKKFMHTTQLKSHMEKVHMQIYKFSCQKCTKGFRYQFEYDKHMKFQHEGLRFRCAHCQKEFKDEPYFREHLKIHDPNYEKTSYSCPYCGNIYHHYNSYTRHMKIHTGEQREHICDICGKILCSGPSLKMHMRTHTGEKPHKCVICGKGFANAATLHIHKRTHTKEKPYVCNVCQKAFSQKPALNVHMKSHTGEKPHVCVVCNKKFITKKAQNEVFSCPTCPKVYGFENQLRNHRCHRQKRKRLVTCEICNITVIAQNLRGHIDRKHLNEYAFSCKLCDRKFRHAIYLKVHVDNIHLNRYKIYCEVCNRGFNFPNELDKHRKFEHEGARYFCKKCPRIFKDCRRFKIHVASHDPDYVEPVYECTECEQRFKQKHSYNKHLRKHGGEKFEYVCETCGRVTTTQTSLREHMLIHTGEKPHECEVCGKSFNKKCLLVTHFRLHTNEKPYECTVCEKTFTQKPALNVHMKYHTGKNLHECQVCGKKYVTKQGVKLERDHNKVYRCENCGKECSSWHQLKTHFRGHETSTKRQIAIKLEEFRCEFCAKLLGDKGTLARHVAEAHHRETRFNCYNCDQKFYHKYMLVRHIKEKHTGRPPTCDICGLEFSTYATLRRHTTDKHNVDYRDLYCYECKKSFVGGISYRKHMRKHTDDGAKFVCTVCGKILSSMSSMRDHMTRRHSEETPYECDQCEKAFTTPLSLKSHKLTHVGPSFKCELCHKQFIQPASLRIHIKRVHVKVRPHQCDICMKFFATRTELNKHHVRCKGPKQEKELKSETILAVGPNTVVTSDEINQPTSGNTAPLETNNDDNHEEQNSPTPRPTPLQNNTNNKDGINTPIRRQKKTVQKITSYESSLLNILQQKQHEEINEEKQFAMMLVPMLQKLNNDQKHYAQIDILNVTRYARNFHPTPFVQYPHTHRSNMVPSTSLGHATAYQLPSQVPSSNFQMEPPGHLQTVSQYSLTNNQRQNSAGSVRTYLSEFSEGLLSPTAGSSSCDYSMASSIIPSYLTCRINNYVVH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-