Basic Information

Insect: Choristoneura rosaceana
Gene Symbol: Zfx
Assembly: GCA_037349165.1
Location: JAZBNJ010000015.1:13480449-13488673[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.00098 0.079 14.4 4.1 1 23 134 156 134 156 0.98

2 13 3.1e-05 0.0025 19.1 3.6 1 23 161 183 161 183 0.98

3 13 0.06 4.8 8.8 0.3 2 23 185 206 184 206 0.96

4 13 7.8e-05 0.0062 17.9 2.5 1 23 221 243 221 243 0.99

5 13 1.3e-06 0.0001 23.5 1.1 1 23 255 277 255 277 0.98

6 13 3.3e-06 0.00026 22.2 3.1 1 23 283 305 283 305 0.99

7 13 4.8e-06 0.00039 21.7 3.8 1 23 311 333 311 333 0.99

8 13 3.3e-07 2.7e-05 25.3 1.3 1 23 339 361 339 361 0.95

9 13 0.0048 0.38 12.2 2.0 1 23 367 389 367 389 0.92

10 13 5.1e-06 0.00041 21.6 0.3 1 23 395 417 395 417 0.98

11 13 0.03 2.4 9.7 5.2 1 23 423 445 423 445 0.97

12 13 1e-06 8.4e-05 23.7 1.4 1 23 451 473 451 473 0.99

13 13 0.00033 0.027 15.9 1.5 1 22 479 500 479 501 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.00098	0.079	14.4	4.1	1	23	134	156	134	156	0.98
2	13	3.1e-05	0.0025	19.1	3.6	1	23	161	183	161	183	0.98
3	13	0.06	4.8	8.8	0.3	2	23	185	206	184	206	0.96
4	13	7.8e-05	0.0062	17.9	2.5	1	23	221	243	221	243	0.99
5	13	1.3e-06	0.0001	23.5	1.1	1	23	255	277	255	277	0.98
6	13	3.3e-06	0.00026	22.2	3.1	1	23	283	305	283	305	0.99
7	13	4.8e-06	0.00039	21.7	3.8	1	23	311	333	311	333	0.99
8	13	3.3e-07	2.7e-05	25.3	1.3	1	23	339	361	339	361	0.95
9	13	0.0048	0.38	12.2	2.0	1	23	367	389	367	389	0.92
10	13	5.1e-06	0.00041	21.6	0.3	1	23	395	417	395	417	0.98
11	13	0.03	2.4	9.7	5.2	1	23	423	445	423	445	0.97
12	13	1e-06	8.4e-05	23.7	1.4	1	23	451	473	451	473	0.99
13	13	0.00033	0.027	15.9	1.5	1	22	479	500	479	501	0.92

Sequence Information

Coding Sequence: ATGCTTAACGTAGATACAACTTGTCGAACATGTACGAAGAATGGAGATAATTTGGTGGATATTTTTGACCCCTGGAAGTCTGAAAATAAGGATTCTGATCAACTTCCAGACTTCTCAGAGGTCTTGAAGACTTTTACGGGAACACAGattaCTAAAGATGATGGATTACCTACAAAATTATGTGAAGAATGTGTCAAAGCTCTTCAATTCATGTTCAATTTTCGTCAACAAGTACTCAACTCCTATGATGAGTTGAAAAGAATGATAGAAGAGCAAACCGATGTGAAGAACGAACATATTGAAATAGATCTTAAGACAGAGGACCAATTTGACTATGATTTCTGTTACGATGATTTCTTACTTGATGATTTTCCCAAACAAGAGAATGAAGAGAAGGGCTTTGTTTGCAATGAATGTAACAAGCACTATGTTAATGAGAAACGGTTTTTGAAACACTTAAAGACACATGAAAAACCTGGCTTTCAGTGTACTATATGTAGTAAAGCTTATCACAGGCAGTCTAATCTGGACCGTCACTTGACTAAACACAGCAAATGTACAATATGCCTTAGTTATTTTGAATCGGAGGCTCTACTATTAAAACATATGAGCGAACATGTTAATGGTGTTGAAATAAAGACTGAGGAAGAAGATGAACTGTACAAATGCTCTGAATGCGATGTGGTTTATACAAAACATAGGTCTTTAGCTATGCATATGAAGAAACATAAGTTCAAAGGGAAAATAGAAGGGAAAAAGGATTATGAATGTGATGTTTGTTCAAAGGAGTTTACGTTAAAAAGCTTATTGCGGAGGCATATGAAGCTGCATAGCAAGGAACGTCCATTCCAGTGCCTGAAATGTAACAAAAGCTATTCTAGACAAGACCAATACAATGATCATATGAATAAACATAATGGAGTCAGGCCTTACGTCTGCCCGCATTGTAGTAAAGCCTTTACGCAGCTCTGCAGCCTCAAGGACCACGTGCGCACGCACACGGGCGAGACCCCGTTCCTGTGCTCGCAGTGCGGCCGCGGCTTCAACAACAGCTCCAACCTGCGCCAGCACATGATGCGCCACACCGGGCTGAAGCCCTTCGCTTGTAACTTGTGCCCCAAACGGTTCTCCACCAAAGGGCAGATGACGTGCCACGTGGGCACGCACACGGGCGCGCACCCGTACAAGTGCGCGCAGTGCGGCGCCGCCTTCACCAAGCCCAACTCGCTCAAGAAGCACCAGCTCATACACCTCGGGGTCAAGCCCTTCGCCTGTGACAGCTGCAGCATGCGTTTCGCGTGCAAGGACCACTTGAAGCGCCACTACCGCATCCACACGGGCGAGAAGCCCTACCGCTGCCAGTACTGCGAGCGCGCGTTCACGCAGAGCAACGACCTCGCCAAACACACGCGCATGCATCTCGGACAGAACATATACCAGTGTACAAAATGCGACATGCGTTTTCGTCTTCTGAGCGAGTTGAAACAGCACTATCCTACGCACTACCTCGCTGACGGAGAACCGCCCTTAATACCAGTGAGTAAGGACGAATCTGCGCCGGTCCTCGTTCTGAAACCGCCTGAGCCCGAGAAAGAGACGGAAGGCACTATTACCATCACTTTCAGCAGCAACGGGCTAGACAAGGATGGGCTACATGGGAATATTACGATTGATATCACACCGCAAAATACTTGA
Protein Sequence: MLNVDTTCRTCTKNGDNLVDIFDPWKSENKDSDQLPDFSEVLKTFTGTQITKDDGLPTKLCEECVKALQFMFNFRQQVLNSYDELKRMIEEQTDVKNEHIEIDLKTEDQFDYDFCYDDFLLDDFPKQENEEKGFVCNECNKHYVNEKRFLKHLKTHEKPGFQCTICSKAYHRQSNLDRHLTKHSKCTICLSYFESEALLLKHMSEHVNGVEIKTEEEDELYKCSECDVVYTKHRSLAMHMKKHKFKGKIEGKKDYECDVCSKEFTLKSLLRRHMKLHSKERPFQCLKCNKSYSRQDQYNDHMNKHNGVRPYVCPHCSKAFTQLCSLKDHVRTHTGETPFLCSQCGRGFNNSSNLRQHMMRHTGLKPFACNLCPKRFSTKGQMTCHVGTHTGAHPYKCAQCGAAFTKPNSLKKHQLIHLGVKPFACDSCSMRFACKDHLKRHYRIHTGEKPYRCQYCERAFTQSNDLAKHTRMHLGQNIYQCTKCDMRFRLLSELKQHYPTHYLADGEPPLIPVSKDESAPVLVLKPPEPEKETEGTITITFSSNGLDKDGLHGNITIDITPQNT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00462615;
90% Identity: iTF_00156466;
80% Identity: -