Cfor000517.1
Basic Information
- Insect
- Chloromyia formosa
- Gene Symbol
- ZEB2
- Assembly
- GCA_964017055.1
- Location
- OZ024813.1:3952336-3959450[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.055 5.6 8.8 0.3 1 23 244 269 244 269 0.94 2 13 0.00089 0.092 14.4 4.1 1 23 304 326 304 326 0.98 3 13 0.00078 0.081 14.6 1.2 1 23 332 355 332 355 0.98 4 13 0.0031 0.33 12.7 6.2 1 23 361 383 361 383 0.97 5 13 6.4e-07 6.6e-05 24.3 0.7 1 23 389 411 389 411 0.99 6 13 0.00093 0.096 14.4 1.8 1 23 428 451 428 451 0.97 7 13 3.6 3.7e+02 3.1 1.9 1 23 456 477 456 477 0.83 8 13 0.00052 0.054 15.2 1.5 2 23 521 543 520 543 0.96 9 13 0.025 2.6 9.9 2.8 1 23 549 572 549 572 0.94 10 13 6.5e-05 0.0068 18.0 0.6 1 23 578 600 578 600 0.98 11 13 0.0053 0.55 12.0 5.8 1 23 606 628 606 628 0.96 12 13 1.9e-05 0.0019 19.7 1.4 1 23 634 656 634 656 0.98 13 13 0.0011 0.11 14.2 3.3 1 23 662 685 662 685 0.98
Sequence Information
- Coding Sequence
- ATGGACGACGATATTGCCGAAGAAGTGTACGATGCAGAAATCATCGAGACGGATATAAATGAGTTGTGCCGAATTTGTGGTAGCACGTCCGACAGTCCCCTGGTGCCGATTTACGAAGAAAGTGGGCTGGTCGAGGAGTTGGCATCGAAAATTATGCTCTATTTGCCAATCAAGatcTCCGAAGACGATGCCCTGCCCGTCAAAGTTTGCGTCAATTGTGCCAATGGCGTCTTGACTTGGCACCTACTTTTCGAATGTTGCGTAGACGCTGATAGACGCTTTCAAGCCATGCTTTCCGAAGTGCATGAAATACGACCCGAATCCCGGAAAAAATCAATCGGCGGCGGAAATATGCATACGACGGATAAAACCCTCGACCAGTCAATGAAAGAGGACGAACTGAACGAGAGAAACCAAGCGGAAGAGCATGAAATGGAGGATGTAATGTTTCTGCGAGCAGAATTTGGACCGGAAGACGAACAGTATCTGGAAGATGAGACACATTTAGCCGATGAAGAACTGGATATGAAAAATGAAGATCAATCGCCAGTGAAACATGCCACTTCATTTGACAATTTTCTTGATCCCTCTACGTCAACATCACCAATCACATCCGACTTTATAGTGTTAGACATAGAACGTCATCCATCACTGGCTGTTGATGTTGAAGATTCCGACGTTTTCGATTGTGAACCCGAACACGGCGTCCCTGAAACGACTGAAAATACTTTTACATGCCCAAGTGACGAATGTCTTGCCGGCTATAACACAAAAAGTGAATTTTGCGCGCACTTAATTGAAGAACATAGAAACAATCCCGAATTACTGATCAAGCTGGGAGATCGAAAATTTCACGTTGACAAGAAAACCATTCGTGATGTAAGGATTATTGTCGATGGTCGTCGTATGTTTAAATGCCCACAATGTGACAAGTTGCTTTCAACATCGTATTGTTTTAAGAATCACCTGAAAATTCACACCAACGAAAAGCCATATGTTTGCTTCTTCTGCAATAAATCGTTTCGCATCTATTCGGGCATTGTACGACACATACGATCAACACATTTACAAATTAAGAAATTCTCGTGTGATATTTGCAATAAGAAATTCACGTGTCGCGATAATCTTCGTCAGCACTTGCATTTGCATGCGGACGTAAAGTCGTACGTTTGTAGTATTTGTGGCAAAGGATTCAAGCAGAAAGCGTCATTGTTTTTGCATACGCAAACACATTCCGATACGTTGCCGTTCAAGCATCGGATATTCAAAAGCCGTCAGCAACATCAGTGTAACTTTTGCAAGGAGGTCTACACGGCAAAGGACTTATTGACCGAGCACTTGAGAAATAATCACTATAATCAGATATTTCATTGTGACGTATGCAATGAGTACAAAGATCAAAATGAACTCATATCACATATGACTCAGCATGCCTTAAATTCGTTACAACACCAGGCGGAGCCAAAAAGTGAGCCTCATCCAGACGAAGCAGCGCCGCAGAATCAACATGCCAAAGTGATAAAACCAAAGAAtaaaacaacagcaacaaccgcTAAACTGAAATGTAAGAAATGTGATAAGATCTTCACTAGTATAAGTGGCGTACACTATCACATGAACTCGGCCCATGCTAAATTGAAAACGTTCAAATGCGATCAGTGCGACAAGGTGTTTTCATGCAAACGCATTTTGGACAATCACATCCGAAGTATGCACGTGAAGAAGAAAATGTATCAATGCGACATTTGCGAGAAGGCGTTCAAAACTGACACGGCTCTCTACTCGCATAAGAAAGTGCACGACAACGTCTTTCCCTACGAGTGCGAGAAGTGCGGCAAAACATTTCGTTTTAAACATCACCATGTTGCCCACTTGGAAATCCACAATTTGGAGAAGAAGTATGCATGCAATATGTGCAACAAGCAGTTTTATGCCAAGGGTAATTTAAGTAAGCACTTAAAAACGCACGAGACAGCACTTGAGTATACGTGTCATATATGTAACGTGAAATTGAAGCAACGGCGCTACCTCTACGAACATATGAAACGTGCCCATCAGCCCATCTTGAACAAGCAGGCTAACAATTAA
- Protein Sequence
- MDDDIAEEVYDAEIIETDINELCRICGSTSDSPLVPIYEESGLVEELASKIMLYLPIKISEDDALPVKVCVNCANGVLTWHLLFECCVDADRRFQAMLSEVHEIRPESRKKSIGGGNMHTTDKTLDQSMKEDELNERNQAEEHEMEDVMFLRAEFGPEDEQYLEDETHLADEELDMKNEDQSPVKHATSFDNFLDPSTSTSPITSDFIVLDIERHPSLAVDVEDSDVFDCEPEHGVPETTENTFTCPSDECLAGYNTKSEFCAHLIEEHRNNPELLIKLGDRKFHVDKKTIRDVRIIVDGRRMFKCPQCDKLLSTSYCFKNHLKIHTNEKPYVCFFCNKSFRIYSGIVRHIRSTHLQIKKFSCDICNKKFTCRDNLRQHLHLHADVKSYVCSICGKGFKQKASLFLHTQTHSDTLPFKHRIFKSRQQHQCNFCKEVYTAKDLLTEHLRNNHYNQIFHCDVCNEYKDQNELISHMTQHALNSLQHQAEPKSEPHPDEAAPQNQHAKVIKPKNKTTATTAKLKCKKCDKIFTSISGVHYHMNSAHAKLKTFKCDQCDKVFSCKRILDNHIRSMHVKKKMYQCDICEKAFKTDTALYSHKKVHDNVFPYECEKCGKTFRFKHHHVAHLEIHNLEKKYACNMCNKQFYAKGNLSKHLKTHETALEYTCHICNVKLKQRRYLYEHMKRAHQPILNKQANN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -