Basic Information

Gene Symbol
-
Assembly
GCA_964017055.1
Location
OZ024813.1:161094989-161097992[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.014 1.4 10.7 0.3 2 23 173 194 172 194 0.97
2 18 1.8e-05 0.0019 19.7 0.1 3 23 198 218 196 218 0.96
3 18 0.23 24 6.8 10.8 3 23 225 246 224 246 0.97
4 18 4.7e-05 0.0048 18.5 0.6 1 23 252 274 252 274 0.96
5 18 0.00019 0.02 16.5 1.0 1 23 280 302 280 302 0.98
6 18 0.00019 0.019 16.5 2.5 1 23 336 358 336 358 0.98
7 18 1.4e-06 0.00014 23.3 0.4 1 23 364 387 364 387 0.96
8 18 1e-05 0.0011 20.5 3.1 1 23 395 417 395 417 0.98
9 18 0.056 5.8 8.8 0.6 2 23 530 551 529 551 0.97
10 18 9.1e-07 9.5e-05 23.8 0.2 2 23 554 575 554 575 0.97
11 18 0.0013 0.13 13.9 5.7 3 23 582 603 581 603 0.97
12 18 5.8e-05 0.0059 18.2 2.6 1 23 609 631 609 631 0.96
13 18 2.3e-05 0.0024 19.4 0.5 1 23 637 659 637 659 0.98
14 18 2.9 3e+02 3.4 0.0 8 23 672 687 671 687 0.92
15 18 0.17 18 7.2 6.6 1 23 693 715 693 715 0.98
16 18 6.1e-06 0.00063 21.2 0.6 1 23 721 744 721 744 0.93
17 18 7.7e-06 0.00079 20.9 1.7 1 23 752 774 752 774 0.98
18 18 0.052 5.4 8.9 2.7 1 23 780 803 780 803 0.98

Sequence Information

Coding Sequence
ATGGCATACGAGTTTGTAGCGCAATGTAAAAAGGCGGATAAACTTCTGCGAGGAAGACTTCATGGAGTCATTAAAATTGAGCCCGTCGACACGCTGCAACAACCTCTCGACAAATCTGACGACGGCTGCGCATCTATAAAAATTGAGCCCATCGAAGGAATCATCGTAAAGTCTATTTTTGATCAGGATAATACGAGTATCATAGTCATCGAAGATTATCCGGAAGACGATATAATCAATCAAGGATTCTTAGACTACAGAGGAATGGAATTTGATGAGAATGATATTATTGAGGTGGACGAAGATTTCGTCGAAGAAACTTCAGACTTGAATAATTGCATTAATTACACTTTTGAAAATACCGCTGAAGTAACGACTGAAAACACCACGCTAACATTGCAGCCTGATATTGATCAGCAAGCCGTCACGAAATCTTCAACGAGATCTAAACGTGTGGCGTCAACTTCCAAAGTAAAGACAAAAAAGCTGTCAAAATTAAAACCGCGCAAAACGTGGACTTGCCCCTTTTGTCCCTCCACTTTTACCGAGTATGCTAAATTCGTGGCGCACAAGAGGTCGCACGGGCTTGCATGCAGGATTTGTGGTAAAAAGTTCAGCAGAGTTGGTGGACTCAAGTCTCATATGGAAATCCATAATGGAAGCAAAGCTTTGTGTCATCTATGCTCTAAGGAGTGTTCGAATCATGGGAACTTAGTACGGCACATAAGACATTGCCATGATAAAATCCGGCCACATTCCTGCGATGTGTGTGGAGCGCAGTTTTCccggagatcgtcattgcaactGCATGTCGCGTCTCATAGTGACGAACGCAATTACGTATGTGATGTGTGCGACAAAAGATTTAAAACACCCATGGCCGTGTATTACCACAAGCGAAAGCATCGGCCTGATTTTGACAAATCGTGGCGCAAAAGATATGAAAAGTGTAATTCGGTTGGAAATTTAATAGTACACAGACTAATCCACTCGGGTGTGAAAGAATTCGAATGTTTAGTGTGTCACAAGGGATTCCACTCTAAGGCTGCCTTAAAGATACATACGCGCATTCACACTGACGAGAGACCTTATAGTTGCGATATATGTGGAAAGGATTTTCGCCAGGCAGCCAACTTGAAAACTCATAAACTTCGTATTCATGAACCAGAAGCTGCCAGACGGTACACATGTAACTTTTGCGAAAAGTGTTTCACAAGTAGCGGTACACTGAGAGTGCACGAGCGAATTCACACGGGCGAGAAACCATACAAATGTGACACCGAAGATTATCCGGAAGACGATGTAATCAATCAAGGATTCTTAGATTACAGAGGAATGGAATTTGATGAGAATGATATTATTGAGGTGGACGAAGATTTTGTAGAAGGAACTTCAGACTTGAATAATTGCATTAATGACACTTTTGAAAATACCGCTGAAGTAACGACTGAAAACACCAAGCTAACATTGCAGCCTGATATTGATCAGCAAGCCGTCACGAAATCTTCAACGATATCTAAACGTGTGACGTCAACTTCcaaagtaaaaacaaaaaagctGTCAAAATTAAAACCGCGCGAAACGTGGACTTGCCCCTTTTGTCCCTCCACTTTTACCGAGTATATGAAATTCGTGGTACACAAGAGGTCGCACGGGCGTGTATGCAGCATTTGTGGTAAAACGTTCAGCAGAGTTAGTGGACTCAAGTCTCATATGGAAATCCATAAAGGAAGCAAAGCTTTGTGTCATCTATGCCCTAAGGAGTGTTCGAATTCTGCGAACTTACTACGGCACATAAGACAATGCCATGATAAAATCCGGCCACATTGTTGCGATGTGTGTGGAGCTCAGTTTTCccggagatcgtcattgcaacaGCATGTCGCGACTCATAGTGACGAACGCAATTACGTATGTGATGTGTGCGACAAAAGATTTAAAACACCCACGGCCGTGAATTACCACAAGCGAATTCACCGGCCTGATTTTGACACATCGCGGCGCAAAAGGTATAAAAAGTGTAATTCGGCTGGAAATTTAATAGCACACAGACTAATCCACTCGGGTGTGAAAGAATTCGAATGTTCAGTGTGTCACAAGATATTCCACTGTAAGGCTACCTTAGAGAGACATACGCTCAGTCACACCGGCGAGAGACCTTATAGTTGCGATATATGTGGAAAGGGTTTTCGCCAGGCAGTCCACTTGAAAACTCACAAACTTGGTATTCATGATCCAGAAGCCGCCAGACGGTACACATGTAAGTTTTGCGAAAAGCGTTTCACAAGTAGCGGTACACTGAGAGTGCACGAGCGAATTCACACGGGCGAGAAACCGTACAAATGTGACCAATGTTTGGCGTGCTTCATTGATATAAAAGGTTTGAAAGGTCATCACCGGAAGGTTCATTCGATGGAGGCGTTGAATGTCGAACAGGAGAATACAACGAAAATAGTTGTATTGGATGAACACTGTTTAACGATTCACGGAAGTGATATTGGCGAATTAAGTATAAATCTGAAAGATACCGTTGACAGCCAAGATGTCTGCTTAGATCCGTATAATGAAATATAA
Protein Sequence
MAYEFVAQCKKADKLLRGRLHGVIKIEPVDTLQQPLDKSDDGCASIKIEPIEGIIVKSIFDQDNTSIIVIEDYPEDDIINQGFLDYRGMEFDENDIIEVDEDFVEETSDLNNCINYTFENTAEVTTENTTLTLQPDIDQQAVTKSSTRSKRVASTSKVKTKKLSKLKPRKTWTCPFCPSTFTEYAKFVAHKRSHGLACRICGKKFSRVGGLKSHMEIHNGSKALCHLCSKECSNHGNLVRHIRHCHDKIRPHSCDVCGAQFSRRSSLQLHVASHSDERNYVCDVCDKRFKTPMAVYYHKRKHRPDFDKSWRKRYEKCNSVGNLIVHRLIHSGVKEFECLVCHKGFHSKAALKIHTRIHTDERPYSCDICGKDFRQAANLKTHKLRIHEPEAARRYTCNFCEKCFTSSGTLRVHERIHTGEKPYKCDTEDYPEDDVINQGFLDYRGMEFDENDIIEVDEDFVEGTSDLNNCINDTFENTAEVTTENTKLTLQPDIDQQAVTKSSTISKRVTSTSKVKTKKLSKLKPRETWTCPFCPSTFTEYMKFVVHKRSHGRVCSICGKTFSRVSGLKSHMEIHKGSKALCHLCPKECSNSANLLRHIRQCHDKIRPHCCDVCGAQFSRRSSLQQHVATHSDERNYVCDVCDKRFKTPTAVNYHKRIHRPDFDTSRRKRYKKCNSAGNLIAHRLIHSGVKEFECSVCHKIFHCKATLERHTLSHTGERPYSCDICGKGFRQAVHLKTHKLGIHDPEAARRYTCKFCEKRFTSSGTLRVHERIHTGEKPYKCDQCLACFIDIKGLKGHHRKVHSMEALNVEQENTTKIVVLDEHCLTIHGSDIGELSINLKDTVDSQDVCLDPYNEI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-