Cv-a017253.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Chloroclystis v-ata
Gene Symbol
Bcl11b
Assembly
GCA_963691955.1
Location
OY829907.1:3005808-3020612[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 22 0.036 2.5 9.1 0.2 1 23 137 160 137 160 0.90
2 22 1.5 1e+02 4.1 2.0 1 23 164 186 164 186 0.97
3 22 3.5e-05 0.0024 18.6 4.4 1 23 191 214 191 214 0.98
4 22 0.014 0.99 10.4 0.8 1 23 218 241 218 241 0.96
5 22 0.019 1.3 10.0 0.2 2 21 254 273 254 278 0.93
6 22 0.078 5.4 8.1 0.1 3 23 288 309 286 309 0.95
7 22 0.031 2.2 9.3 0.8 1 23 327 350 327 350 0.90
8 22 0.002 0.14 13.1 1.2 3 23 368 388 366 388 0.89
9 22 0.0044 0.31 12.0 2.8 1 23 394 416 394 416 0.92
10 22 6.4e-07 4.5e-05 24.1 0.5 2 23 422 443 422 443 0.97
11 22 0.077 5.4 8.1 1.3 1 19 449 467 449 468 0.93
12 22 0.0031 0.21 12.5 0.8 1 23 652 674 652 674 0.98
13 22 0.00025 0.018 15.9 0.4 1 23 681 704 681 704 0.95
14 22 0.0015 0.11 13.5 0.2 1 23 735 758 735 758 0.95
15 22 6.7 4.6e+02 2.0 0.1 2 23 796 818 795 818 0.90
16 22 0.0022 0.15 13.0 2.9 1 20 824 843 824 848 0.94
17 22 0.00049 0.034 15.0 4.7 2 23 874 895 874 896 0.94
18 22 0.026 1.8 9.6 0.5 1 21 902 922 902 926 0.91
19 22 0.0062 0.43 11.5 2.7 3 23 991 1011 989 1011 0.94
20 22 0.0053 0.37 11.8 0.4 1 23 1017 1039 1017 1039 0.98
21 22 2.8e-05 0.0019 18.9 4.7 1 23 1044 1066 1044 1066 0.98
22 22 0.0015 0.1 13.5 0.4 1 23 1072 1095 1072 1095 0.96

Sequence Information

Coding Sequence
ATGAAAAACCCAAACCAAAATAAaAATGATTTGAATCAACCTTTtgacaataaacaaaatgatgGTAAAACTGAGGAAATTGATTCAGACGATGACAAATGTCTCATCGATTTTGTGAAGCCCAAGCTTAAGGTTAGAGTTAGGAAGAAGAAATTACATATTGAAAATTCAGTTGATAAGAAGATAACTAAACAACGGAAACCACTCAAAGACCACAAGGAGTACGAAAGCGTGTTCGACATTCAACTGTTCAGAACGGAAGCGGAAATACTACAGGAGTTTGACAGCCGGAAGTCATGTCCGCGATACATCGCCGCGGCCCACAAGTGTCCCGTCTGTTACACCGTATACAAGTGCCAGAAGCTAAGGGATTTTCATATGAAGTGGCACTTACCGTCCGCGGGTGAGTTCCCGTGCGGCGTGTGCGCGATGCGGTTCCGGTCGCGCGCGGCGATGCGCAAGCACAAGACGGACGTGCACTTCGGACGGTTCGCCTGCAAGAAGTGCCCGCTCATCACATACCACAAGATGGTTATGATCCTGCACTACAGAAAACACCAAGGAGTCAGCTATGTTTGTAAGATTTGCAACAAGACTTACAACCACAGTTCTACATACATGTCACATTTACGTAAGTCACATCGCACTGAGCATGTGTGCGTGACGTGTGCTCAGACGTTTGTGTCCGAAAAAGGACTCACTGTGCATCGCAAGAAGGTACATAATACATCCAGTAAAGTGGACGCCAATGCGTCCGCTCGCTGCGAGGAGTGCGGCGTCACGTTCGCGGACCAGCGCGTGTACACCGTGCACCTCATGAACACCACCAAACACAAGCACGTGGCAGAAACACTCATCGCGTGTCCAGAATGTGGTATCCATTTACCGGACAAGTTGTCCGTACGAGCGCACCGCAGAGAGAAGCACCCCCAGTACAACTTCAGCGCCATGAAGCGAGCCGAGAGCGGACTGACGGGACACGTCTGCCCATTGTGTGGAGCATCCGGAACCCACAATACCTGGCTATACCGCCATTTCCTGGCCTCCCATCCATCGCACAACTACGAGCTATGTGTGGCCTCCGAGCGACGCCGGCACCTCTGCGACCAGTGCGGGAAGAGCTTCTACAATATAACCCAGCTAAAGGAGCACGCGTTCGCACACGCGGGACTCAAACCGTTCCGCTGCGACAAGTGCCCGGCCGCTTTTAGCTCCAAGTCACATCTTAAGtttcattcAGAAAGACACGCTCCGCCTAAGAGGGAATGCACTCAATGCGGCAAGAAATTTGTCAGCGCAGCCAACCTCTCAAACCATATGAGATCTCACATCGGCGACCGCCGCTACAAATGCTCGCTCTGCGGCAAAGGCTTCCTTCATTGCGCCGCGCTGAGGGAACATGAACCGGAACTTAATGATGAACACAACCGAACAACAAATGATAATGAATATACAACTAGTAATCCATCTCCAAATACAACACTCGAAATCAAATTAGAACAAGACGACTTAACAAACACTGAAGAAATTAATGATATTAAACCTGATCTAAGACACAAAGAGATAGATGAACTCATTAACCTTAAAGTTGAAGACACATACGACGATTCAGgcaattatgatgatgatgattatttaccactgaagaagaaaaagaaacTAAAGAAAGAAGAGAGAGAAAAAGATGGGAAAATAGTAAAAAGCAAAACAAATAGAACTGCTAATAAGAAGAAACTTAGAGATAGGATTTTAGAGTTGTTTAAATGTGGAGAATTTCAAGATTTAGATACAAAACAAGAGTTAGACCGGTTGAAAGCTTACCTACTTAACCTACTGAATAAGAACAATCCAGAATACGAGGACATGTTCAATATAACGATACTGGACACAGATGAGCTTAAGCAACAAGAATTTGACGGACGGAAACACAGCAAGGAGTATTTAGAAGCGGAGTTCAAATGTGAGATATGCTATAAAGCGTTTGAGGTACAAAGGTTGTTGGATTATCATAGGAAATGGCATGAGCCGTCCACAGGTGCGTATGTGTGTTCCCTGTGCGGTATGCGGTTCGCGCGCTACAAGTCCCTCGCGCAGCACGTCAAGGACAACCACTGCGCCGTGTACCGCTGCACGCTGTGTGCGCTCATCACATACAACttCTCAGTGATGGtgaatcattatcatcatcacaagGGGAAGGAGTACCCGTGCCCCGTCTGTCTGAGCGTATTTAGCAATAAGAGTACAATGAACAACCACCGACTGCAGGCGCACAAAACAGCGCACATCTGTCCGTTCTGTGCGCGCTGCTTCGTCTCAGAGAAGGGCCTGTACTTCCACAAACAACTTAAACACAAGGATGAGGAAGTAATGCAACACACAGTGTCTTGTGACAAATGTTCCGCTCAGCTCAGCTCCGAACAGATCCTACAGGAACACATTCGACAGATGCACGCCGCTACAACTATTCACAAATGCTACCATTGCAAGGAAGTGTTCCGATCTCTGGACGAGCTGAAGCAGCACAAAGTCGCGTCCAACCACCTGCGGTCGCCGCGGACTGTTCATAAGAAAATACTACATAATGCGCCCGTACCCCTGAATAGTGAAGAGAAGCCCTACTGTGAAGAGTGTGACAAAACTTTCAACACTCGGCAAGCATATCTCCGACACCACAACATGCATCACAATACTAACAGAATtcaCAAATGCGGTTTCTGTCAAGCCAAGTTCACTTCCATTGAAGAGCTCGAGGCGCACAGACTGGCGAACAACCATCACTTGAAGGAAAAATGCGTCAAGCGACGAACACGCGTCAAAGCGCCGACTGACAAGCCGACTGAGAAGTGCGAACTGTGTGGAGAGTCAGTAGACACGGTCCGGGTAAAAAGCATGTACCAGCACTTCGTGACGTCACACCCGGACACGCCCTACTCCTCCGTGTACCGGAACCCGCACAACCGCCATCTTTGCGAGCTCTGCGGAAAAACATTCAAGGACCTCCGCTTCTTCCTGGACCACCGCAACTTACACACGGGCGAGAAGCCGTACCGCTGCGCCGTCTGCGCGCGCTCGTACGCCAGCAAGCGGCACCTCGGCTGGCACGTGGCGCGCCACGGCCCGCCGCGACACCGCTGCACCCTGTGCCACAAGATGTTCAACAGTGCCGCCAATCTGTTCGCGCATCGACGGAGTCACGTTGGCGATCGTCGCTTCAAATGCGATATCTGCAGTAAAGGTTTCTTGCACCAAGCGGCGCTCAAGGAGCATGTTCGCGGCGTCCACAACCACATTCGACGAACCAGAAAGTGTAGGGACAAGTGA
Protein Sequence
MKNPNQNKNDLNQPFDNKQNDGKTEEIDSDDDKCLIDFVKPKLKVRVRKKKLHIENSVDKKITKQRKPLKDHKEYESVFDIQLFRTEAEILQEFDSRKSCPRYIAAAHKCPVCYTVYKCQKLRDFHMKWHLPSAGEFPCGVCAMRFRSRAAMRKHKTDVHFGRFACKKCPLITYHKMVMILHYRKHQGVSYVCKICNKTYNHSSTYMSHLRKSHRTEHVCVTCAQTFVSEKGLTVHRKKVHNTSSKVDANASARCEECGVTFADQRVYTVHLMNTTKHKHVAETLIACPECGIHLPDKLSVRAHRREKHPQYNFSAMKRAESGLTGHVCPLCGASGTHNTWLYRHFLASHPSHNYELCVASERRRHLCDQCGKSFYNITQLKEHAFAHAGLKPFRCDKCPAAFSSKSHLKFHSERHAPPKRECTQCGKKFVSAANLSNHMRSHIGDRRYKCSLCGKGFLHCAALREHEPELNDEHNRTTNDNEYTTSNPSPNTTLEIKLEQDDLTNTEEINDIKPDLRHKEIDELINLKVEDTYDDSGNYDDDDYLPLKKKKKLKKEEREKDGKIVKSKTNRTANKKKLRDRILELFKCGEFQDLDTKQELDRLKAYLLNLLNKNNPEYEDMFNITILDTDELKQQEFDGRKHSKEYLEAEFKCEICYKAFEVQRLLDYHRKWHEPSTGAYVCSLCGMRFARYKSLAQHVKDNHCAVYRCTLCALITYNFSVMVNHYHHHKGKEYPCPVCLSVFSNKSTMNNHRLQAHKTAHICPFCARCFVSEKGLYFHKQLKHKDEEVMQHTVSCDKCSAQLSSEQILQEHIRQMHAATTIHKCYHCKEVFRSLDELKQHKVASNHLRSPRTVHKKILHNAPVPLNSEEKPYCEECDKTFNTRQAYLRHHNMHHNTNRIHKCGFCQAKFTSIEELEAHRLANNHHLKEKCVKRRTRVKAPTDKPTEKCELCGESVDTVRVKSMYQHFVTSHPDTPYSSVYRNPHNRHLCELCGKTFKDLRFFLDHRNLHTGEKPYRCAVCARSYASKRHLGWHVARHGPPRHRCTLCHKMFNSAANLFAHRRSHVGDRRFKCDICSKGFLHQAALKEHVRGVHNHIRRTRKCRDK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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