Basic Information

Insect: Chironomus tentans
Gene Symbol: L
Assembly: GCA_963573255.1
Location: OY754304.1:9357151-9374970[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 2.8e-05 0.0015 19.1 2.0 1 23 132 154 132 154 0.98

2 16 0.12 6.2 7.7 4.2 1 23 160 182 160 182 0.98

3 16 2.8e-05 0.0015 19.1 3.2 1 23 188 210 188 210 0.99

4 16 4.6e-05 0.0024 18.4 0.5 1 23 216 238 216 238 0.98

5 16 0.18 9.3 7.1 1.6 2 23 293 316 292 316 0.91

6 16 0.00075 0.04 14.6 0.3 2 23 339 361 338 361 0.95

7 16 0.29 15 6.4 0.6 1 23 453 475 453 475 0.95

8 16 0.0028 0.15 12.8 0.4 1 23 529 552 529 552 0.92

9 16 0.46 24 5.8 0.4 1 23 555 578 555 578 0.95

10 16 0.11 5.7 7.8 3.2 2 23 582 604 581 604 0.96

11 16 0.12 6.4 7.6 2.5 1 23 637 659 637 660 0.95

12 16 0.026 1.4 9.7 0.3 2 23 836 860 835 860 0.93

13 16 0.18 9.3 7.1 0.0 1 23 866 888 866 888 0.95

14 16 0.092 4.9 8.0 2.8 2 23 895 916 894 916 0.98

15 16 0.0033 0.17 12.6 0.2 2 23 1027 1048 1026 1048 0.96

16 16 0.027 1.4 9.7 1.8 3 23 1059 1079 1058 1079 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	2.8e-05	0.0015	19.1	2.0	1	23	132	154	132	154	0.98
2	16	0.12	6.2	7.7	4.2	1	23	160	182	160	182	0.98
3	16	2.8e-05	0.0015	19.1	3.2	1	23	188	210	188	210	0.99
4	16	4.6e-05	0.0024	18.4	0.5	1	23	216	238	216	238	0.98
5	16	0.18	9.3	7.1	1.6	2	23	293	316	292	316	0.91
6	16	0.00075	0.04	14.6	0.3	2	23	339	361	338	361	0.95
7	16	0.29	15	6.4	0.6	1	23	453	475	453	475	0.95
8	16	0.0028	0.15	12.8	0.4	1	23	529	552	529	552	0.92
9	16	0.46	24	5.8	0.4	1	23	555	578	555	578	0.95
10	16	0.11	5.7	7.8	3.2	2	23	582	604	581	604	0.96
11	16	0.12	6.4	7.6	2.5	1	23	637	659	637	660	0.95
12	16	0.026	1.4	9.7	0.3	2	23	836	860	835	860	0.93
13	16	0.18	9.3	7.1	0.0	1	23	866	888	866	888	0.95
14	16	0.092	4.9	8.0	2.8	2	23	895	916	894	916	0.98
15	16	0.0033	0.17	12.6	0.2	2	23	1027	1048	1026	1048	0.96
16	16	0.027	1.4	9.7	1.8	3	23	1059	1079	1058	1079	0.97

Sequence Information

Coding Sequence: ATGACAAGGAGGAAGCAACTGAAGCCTCGTGCTTTGACAAAACATAATGCCGAAAATAATACAGCAGAAGAGGATAACAAGACGCAACTATCAAGTCCCAATGATGATGACCAAATGCAAGGAGCAGATGAGATAGAGCAGAAAAGCAGTACAGTCGCCAACGAGGAAGAAAATGACGAGCCGGCGACTAACAAGGCAGCAAATTATGACTCTGACAATTCGGATTGTGACAGTGTTGGATCATACTCGTCAGAACTCTACTCATCACATTCATCAATCAGCTTCCCATCGTCAAGCAATAGCACATCAGAAATGGAAACAAATGGAATTGATGTTAATGATCCGAttaagaaagagaaaaaggaTAAGACGAAATTTAAAGGAGCATCCAGTTACAAATgtcaattttgtgagaaatcCTTTCCACGGTTGGGATATCTCAAGAAGCATGAACAGAGTCATGAAGATTATATGCCATTTAAATGCCCTGTATGTCTTCGATTATTTAAGCATAAGAGATCTCGGGATCGGCATTTGAAGCTTCATACTGGAGATAGGAGGTACAAATGTCTGTTCTGTGAGTCTGCATTTTCAAGGAGTGATCACCTGAAAATCCACATGAAGACCCACGACAGCAAGAAAGCATTCCAATGCAACTTTTGCAACCGTGGATATAACACAGCCGCAGCTCTTACGTCGCACATGCAAAACCACAAGAAACAGAATGAACTTCGAGAAAGGAACGAGTCTCCTTACAATTATAGCATGAAGTCATCAGAGTCATCTACGACTTCAATGGCCGATAAGAAAAGGTTGGAAATGGCTTCACCAAAATCAGTAAAATCCGATGGACAGTGTGAGTTAAAGAATCAAATTCGATGTTTTTACTGCACAAAGACAAATTTCGTGTCACTGGAGCAATTAACACATCACATTAATGTCATGCATAATCATAGATTTatgaaggaaagaaagaatAGAAGTGAACATGAATTGTCGTCTGCTCAATATATATCATGTGAATattgtttaatgaaatttacatcGTCGGAAAAGCTCATTAAGCACATTAATTTAGTTCATGAAGATAGAATGCAAGGAAcgaatgatgaatttttgagtcCAAAGCTAAATGAATcttccaataataataatattaatgcaCAGCATTCGAATGAAGGAAGtataagcaataaaaaattggcaCATAGATACAGCGACGAGCAACCAACGGATTTAAGTCAGAGGATTACGAAGAagattaaaatggaaaattattcaattccaAAGCATTTTGATGCACagattaataataataataatagccGAACAGCAGCACCTGGTACACCGGATGTTTTTTTATGCAATCAATGTAATGCATCTTTACCaagttttgaactttttcgGCTACATCTAAAGAACCATCTCGAAGAGAATTATGGAAGTAGAAGTAGCGAGCATTTTGAATTGAGCAATGCATTCTATCAGCACTCACAGAAGAAATTTGTATGTCAGCAATGTCGAGATGTTGTGTTTGATAATCGTTTTGAATATGATCAGCATGTTGAGCAGCATTATACCGAGTTTTTGTGTCAAGAATGTGACGATACGTTTACGAAAAATGAGGACTTGCAGAATCATTTGCTTGAGAATCACGTCCGCTTTAAGTGTACGCTGTGCAATGAAAATCTTGAGTCCATAATATCactaaaattacattttgcaACACGACATTCGGATAAAAGGTGCTCTGCATGTCACGATGTCTTTCGAAACGAAAGAgactttaaaaatcatattcagaCAAAGCATTCAGCTGTTGACTTAATAAAATGTATCTTTTGTCGCGTCACATGCTCGTCAGAACTTGAAAtgcatttccattttctctcATCGCATGTCAAGCAGTTTAGATGTCCAGCATGTTCTGAATCATTCcatgttgaatttttacttGACCGACACCTTCAAAATCATCATTCCGTTAATGAGGCTCCAACCAACCCAACCACCTTCAATTTAGAAAAGGAAGCAAGTGCGCTAAATCTACAGAATTACCATGCATCATTAATTGATAGTTATCGAGAGAAATTCCTAATGAATCATGATCCAAAGCTTCCCGACGCAAATTTCCTACATAAACTTaatccaacaatttttccattaaattccTTACATAATCAATATCCAAAAAGTATTAACTTAAATTCATTACATGATAGTCTTAGTAGAGTACAGACAAGTATTGATGAACAGAACCAACCGCAAGGCATGAGAGTCAAGCATTTATATAGTCTGGCAAATGACTCAAAATCTGTCAATTCTGAAGCTCAAGCTTCTTCctataaaattcagaattcgACAAATTCCAGCGTTACCACAAATGATAAGAATAACAATAAGAACTCGACATTTAAGGATAAAAGTGAACAACCTCAACTTGAACTACCAACGGAAAAATCTAGTCATATCATTCATCTTAATACTAAAACTGGCGTTAGCTTGAAATGTGCTTATTGTGAGGCTCGTGAGGACTTTAAATCTAGaaCTGAATTGGAGAATCATATGAAAATTCAGCATAATATCGCCGCAAAACATAAATGCTCaatttgtgatgaaattttaccAAGTCCCGCGGTATTAGCTGAACATAAACTACAGCACTGTAAAGTCATATCTGGAAAATGCTTCCATTGTTCAGAGTCAATTAAGGACATTGGCGATTTCAAGCATCACATCCAAAGCCACAATCAAAAGAACAAAAACTCGTTAGAACTTCCTGTGCATTGCATCTGCTGTCATCAGCTATTGACGTCTGATTTCGAGATTAATCTTCATGCCAAATTCCACACAAACACAGTAAGTTCAACGGCCACAAATGAAGACAAAACGTGTGCACTTTGTCTATCTGCACTAGAAAACAccaatttgaagaaaatctgCAATTCGTGTATGATGAAGCATAACTTTTCGCTGTCCAAAAATCAGCTACAGCTATGTAATCTCTGCAAACAAAATATCGAAGGTGATAAGTTCCAAGACCATTTAATTGAGCATGCATTTGACACTGAATCAATAACTTGTGTTGTTTGTAATGCgatattttcaacaattcatGGCTTAAAAGAGCACATCAGAGAGCACAAATTAACACCAGCAGATTTTAAAGAGGCATGCACGAAATGCAATGctagatttttatattcatcagAGTTACTTCATCACATGAAAGAACATGAGATTGTGGAAAGTCAAGCAAAGACAACAATTAAGCAAGAAAATCAGGAAGAGCCAATAATTATGAAGGAGATTAAGGATGAGGAGGAAGACGACTACATTGAGATTGAAAAAGTtccagaaaattaa
Protein Sequence: MTRRKQLKPRALTKHNAENNTAEEDNKTQLSSPNDDDQMQGADEIEQKSSTVANEEENDEPATNKAANYDSDNSDCDSVGSYSSELYSSHSSISFPSSSNSTSEMETNGIDVNDPIKKEKKDKTKFKGASSYKCQFCEKSFPRLGYLKKHEQSHEDYMPFKCPVCLRLFKHKRSRDRHLKLHTGDRRYKCLFCESAFSRSDHLKIHMKTHDSKKAFQCNFCNRGYNTAAALTSHMQNHKKQNELRERNESPYNYSMKSSESSTTSMADKKRLEMASPKSVKSDGQCELKNQIRCFYCTKTNFVSLEQLTHHINVMHNHRFMKERKNRSEHELSSAQYISCEYCLMKFTSSEKLIKHINLVHEDRMQGTNDEFLSPKLNESSNNNNINAQHSNEGSISNKKLAHRYSDEQPTDLSQRITKKIKMENYSIPKHFDAQINNNNNSRTAAPGTPDVFLCNQCNASLPSFELFRLHLKNHLEENYGSRSSEHFELSNAFYQHSQKKFVCQQCRDVVFDNRFEYDQHVEQHYTEFLCQECDDTFTKNEDLQNHLLENHVRFKCTLCNENLESIISLKLHFATRHSDKRCSACHDVFRNERDFKNHIQTKHSAVDLIKCIFCRVTCSSELEMHFHFLSSHVKQFRCPACSESFHVEFLLDRHLQNHHSVNEAPTNPTTFNLEKEASALNLQNYHASLIDSYREKFLMNHDPKLPDANFLHKLNPTIFPLNSLHNQYPKSINLNSLHDSLSRVQTSIDEQNQPQGMRVKHLYSLANDSKSVNSEAQASSYKIQNSTNSSVTTNDKNNNKNSTFKDKSEQPQLELPTEKSSHIIHLNTKTGVSLKCAYCEAREDFKSRTELENHMKIQHNIAAKHKCSICDEILPSPAVLAEHKLQHCKVISGKCFHCSESIKDIGDFKHHIQSHNQKNKNSLELPVHCICCHQLLTSDFEINLHAKFHTNTVSSTATNEDKTCALCLSALENTNLKKICNSCMMKHNFSLSKNQLQLCNLCKQNIEGDKFQDHLIEHAFDTESITCVVCNAIFSTIHGLKEHIREHKLTPADFKEACTKCNARFLYSSELLHHMKEHEIVESQAKTTIKQENQEEPIIMKEIKDEEEDDYIEIEKVPEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00320040;
90% Identity: iTF_00320040;
80% Identity: -