Cten015355.1
Basic Information
- Insect
- Chironomus tentans
- Gene Symbol
- ZFY
- Assembly
- GCA_963573255.1
- Location
- OY754305.1:3251296-3254418[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 6.1e-05 0.0032 18.0 1.1 1 23 592 614 592 614 0.96 2 15 0.001 0.053 14.2 1.3 1 19 619 637 619 639 0.95 3 15 3.4e-05 0.0018 18.8 0.5 3 23 642 663 641 663 0.92 4 15 0.0014 0.076 13.7 0.2 1 23 672 694 672 694 0.97 5 15 3e-05 0.0016 19.0 1.5 1 23 703 725 703 725 0.97 6 15 0.24 13 6.7 2.3 2 20 731 749 730 751 0.88 7 15 1.8e-05 0.00096 19.7 2.0 2 23 752 774 751 774 0.95 8 15 0.0008 0.042 14.5 0.6 1 23 783 805 783 805 0.95 9 15 0.0032 0.17 12.6 0.9 1 23 811 834 811 834 0.98 10 15 5.3e-06 0.00028 21.4 1.8 1 23 867 889 867 889 0.98 11 15 4.1e-05 0.0022 18.6 1.6 1 23 893 915 893 915 0.97 12 15 5.4e-06 0.00028 21.3 2.8 1 23 921 943 921 943 0.97 13 15 0.13 7.1 7.5 4.3 2 23 951 972 950 972 0.97 14 15 0.025 1.3 9.8 0.7 2 23 987 1009 986 1009 0.96 15 15 0.00031 0.016 15.8 4.3 1 23 1014 1037 1014 1037 0.96
Sequence Information
- Coding Sequence
- atgcCAAAACGCCGACGAACAGCAAGTCTGCAAAACCAAAATCACCTTCCAGACGACGTCAGGATAAAGATTGAAAAGGACTGTGAGGATGAAGAATCGCTTGTCATTCAGAACTTCCAATTAACATCAAGTTTCGATGAAGCAAGCAAAATCAAGAAAGAAACTGAgattaattatgaatttattgttgAGGATAAGGATGAGTCAAATGAGAAGATACAGCAAGATGCTGAGGATGGTCCAACATCGGACGATGAAGTTGAGTCCAGCTCTGGAAATGAGGaagatttaaatcaaaaatttacgaaTAAACCTCACGTAAATGAAGTTCATGTAAAATTGGAACCTGAAGAGTATTTCGAGTCAACAGCAAGTCACACCTTGGATAACCAACAGAACAATGAAGAACTGCTCAACTCACAAGACATAAAAGAAGAATTCATGATAATCAAGGAAGAAATACAAGATTTTGGAGTTGATTTGGttaaaattgaagttaaaatcacaaaagttGACATGGAAATAGCCGAACCTTATGCAAAGAAGCTTAAACTTGACCAGCAGAACGCTACAAGCAGAAATTCAACAAGAGGAAGGAGGTCTGTTCCAAAAGTTACcgaaaaaactacaaaatctACAAGTTCTGATAAAACTGCTGCAAAGGAGGATGaaggtagaaaaaaatcattaaaaaatgccaaaattttatcaaaaagtaaaaaaactGAGGACATTGAGACAACGTCAAAGAATTTTAACTCTGATCAAGATAATGAATCACACTTTGATGATGGTAATGATGTAATATCAACAGCAAGTCATGACTCAGACTCGAATTCATCAAAATCGTCAAACAACAGGATAAAAACCTCAGAATTATCAACAAAATCGAGAAAAGCTGCTCCCAGAAATGactcgaaaaattcaaaaaatattcaaaatttgtcaaattccTCATCAAAGTTAAAATCATTTCCAAATTCGACTTCAAAGAATAAAAACGTTGACAATTCTGGTTCAAGTTTTACAGAAAGCAGTAAAAGTGATCCAAAATCCactaaaaactcaaaaattgcCAACGATTTAGAACAAAAAGGTGAAaagtatttcaaaatttttgatcagtCCAAGCCGCAAAGTCAAAAAAGTAGCACTAAAACATCAGATCCACAAAACTCAAAACAAAAGTCCAAGGATCCAAGTGAATCATCAAAAGATCCAACTAAGTCTTCAAAAGATTCAAAcaagtcatcaaaaattccaagtaaatcatcaaaaaattcatcagaatCTGTATCTTCAGCAACAAAACCTGGTCCATCCAAGAAACCAAACAGAAAGTCACGCAGTTCATTGATTAAAGATTCCAATTTTGTCGATAAAATTCCTGAAGACACAAATCTTCAAGACACAAAAGTCAACCTCAAACACTCCTCGAATTCTGACAGAAAATCTGTATTTATTGACAACAACGAAGCCAATTCTATCTTATGCTCAAGATTAAGCATTGAGGATACCAAAGATCCAAGATTAGCTGAACTTTTCAATGATTTCTCAGTTAAAAATGAACAAGGAACAGAATTAACCTCAAAAGCGTCTCAAATAAATccagaaaattctcaaattgaCTCCAAAAATGCAGACATCATGAAATTACATCAAATGCACTTAGATGCATTGGGTATTGGTGATATTAATGCTGGTTCCCTCAATTTACCATCAACATCCAAAAGACAGCCAAAATTGCCATCAAAATCCACCCCAAGAAAGGAATTCCAATGCAAATTATGTCCAAAGTCATTCGACAAAAAATTGAGTCTCAAAAACCATCAAGCAGCTCACGTTGCATATGACTATCCATGCAAAAAATGTGGAATggaattcaaaactttaagAGCTCTCAAGAATCATGAATGCCCAATTTGTACAATTTGTGGTAAAAAGTTCAAGAACAAACCAAAATTAATCAGACATGTCACTTATGTCCACTCAGAAAAATCAAGTTTGAAACTATTTTCATGTGATTTATGTGGAAAGGcactaaaatataaaatatcaattgaaAGACACATGATTGAGCATTTGGAAGtgacgaaaaatttaaaattcaaatgtgaGATCTGCAACAAGAATTTTAAGAAGCGGATGGGACTGCAGAACCACCAGATCCTTCATGTCTTTGCGACactttcatgcaaaaaatgtgGAGTGAGTTTTAAGAAGCAGAAGCCATTCGATCAGCACAAGTGCCTGTCCTGTACTCACTGCCCAAAGATATTctcatcaaaaacaaaacttaATGATCACATCAGGAACATCCATACTGATGAGTCAGAACTGAACCTTTTTATGTGTGATTTCTGTGGTAAAACCTTCAAGTATCGTCCTTCAATCGTCAGACATGTCCTGGATCATCGCGAGGAAGCCAAATACAAATGTGAAGTTTGTGGTAAGAAATGGAAGTCAGATATTGCTTTAAAGGATCATATCCGGATGTGTCATGCAGCTGAGCTTATAACCTGTAAGATTTGCTTCAAACAGATGAAACCACAGTGTATTTATCAGCACATGAAGTATGTCCACACATCAGTCAGggattttaaatgtaaaatttgtgaTGCTGATTTTAAAACGAAAGAAAAGCTGAAAAGACATTTGGACACGCACAACAGGAAGTTCAACTGTGACCAGTGCACCAGAAAATTCTCATCACAATACGAACTGACTGAACATCTCAAATGGCATGAAGATCCAGAAGTTTTCAAATGCAGCATctgtaaaaaatcattttcaactcGAACAAGCTTGACGACTCATGCTAAGCTTCATAAAGGCATTGTGAGGAACTTGCAGTGTCCACATTGTCCATTCACAACTCACCGAAAAGAAAGCATCAAGTATCACCTGACGACACACGAAAAACgcgataaaaaattagaaatgaagaaaagttgGCTGAAATGTGAGAAATGTGGAGCACTGTTGAAGAACAAGGCATCACTTTGGGGTCATCACCGTAAAGTTCATCCTACTGAGAGATTTACATGTGATCATTGTGGAGTTGTTGTTAAGACGAAGCACAGCTTGAAGCATCACATTGAGGTCAAACACATGGGACAGTAA
- Protein Sequence
- MPKRRRTASLQNQNHLPDDVRIKIEKDCEDEESLVIQNFQLTSSFDEASKIKKETEINYEFIVEDKDESNEKIQQDAEDGPTSDDEVESSSGNEEDLNQKFTNKPHVNEVHVKLEPEEYFESTASHTLDNQQNNEELLNSQDIKEEFMIIKEEIQDFGVDLVKIEVKITKVDMEIAEPYAKKLKLDQQNATSRNSTRGRRSVPKVTEKTTKSTSSDKTAAKEDEGRKKSLKNAKILSKSKKTEDIETTSKNFNSDQDNESHFDDGNDVISTASHDSDSNSSKSSNNRIKTSELSTKSRKAAPRNDSKNSKNIQNLSNSSSKLKSFPNSTSKNKNVDNSGSSFTESSKSDPKSTKNSKIANDLEQKGEKYFKIFDQSKPQSQKSSTKTSDPQNSKQKSKDPSESSKDPTKSSKDSNKSSKIPSKSSKNSSESVSSATKPGPSKKPNRKSRSSLIKDSNFVDKIPEDTNLQDTKVNLKHSSNSDRKSVFIDNNEANSILCSRLSIEDTKDPRLAELFNDFSVKNEQGTELTSKASQINPENSQIDSKNADIMKLHQMHLDALGIGDINAGSLNLPSTSKRQPKLPSKSTPRKEFQCKLCPKSFDKKLSLKNHQAAHVAYDYPCKKCGMEFKTLRALKNHECPICTICGKKFKNKPKLIRHVTYVHSEKSSLKLFSCDLCGKALKYKISIERHMIEHLEVTKNLKFKCEICNKNFKKRMGLQNHQILHVFATLSCKKCGVSFKKQKPFDQHKCLSCTHCPKIFSSKTKLNDHIRNIHTDESELNLFMCDFCGKTFKYRPSIVRHVLDHREEAKYKCEVCGKKWKSDIALKDHIRMCHAAELITCKICFKQMKPQCIYQHMKYVHTSVRDFKCKICDADFKTKEKLKRHLDTHNRKFNCDQCTRKFSSQYELTEHLKWHEDPEVFKCSICKKSFSTRTSLTTHAKLHKGIVRNLQCPHCPFTTHRKESIKYHLTTHEKRDKKLEMKKSWLKCEKCGALLKNKASLWGHHRKVHPTERFTCDHCGVVVKTKHSLKHHIEVKHMGQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -