Basic Information

Insect: Chironomus tentans
Gene Symbol: -
Assembly: GCA_963573255.1
Location: OY754303.1:32649561-32651844[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00017 0.0087 16.7 3.2 1 23 141 163 141 163 0.98

2 12 0.00033 0.017 15.7 0.3 1 23 170 192 170 192 0.96

3 12 0.00014 0.0076 16.8 0.1 5 23 210 228 206 228 0.92

4 12 2.3e-05 0.0012 19.3 1.0 1 23 237 259 237 259 0.98

5 12 4.1e-06 0.00022 21.7 2.2 1 23 265 287 265 287 0.99

6 12 3e-06 0.00016 22.1 4.3 1 23 293 315 293 315 0.98

7 12 1.5e-07 7.9e-06 26.2 1.4 1 23 321 343 321 343 0.95

8 12 0.0044 0.23 12.2 3.5 1 23 349 371 349 371 0.98

9 12 1.5e-05 0.0008 19.9 2.1 1 23 377 400 377 400 0.97

10 12 9.5e-05 0.005 17.4 5.4 1 23 406 428 406 428 0.97

11 12 0.00037 0.019 15.6 2.0 1 23 434 458 434 458 0.97

12 12 0.00014 0.0072 16.9 0.7 1 23 465 489 465 489 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00017	0.0087	16.7	3.2	1	23	141	163	141	163	0.98
2	12	0.00033	0.017	15.7	0.3	1	23	170	192	170	192	0.96
3	12	0.00014	0.0076	16.8	0.1	5	23	210	228	206	228	0.92
4	12	2.3e-05	0.0012	19.3	1.0	1	23	237	259	237	259	0.98
5	12	4.1e-06	0.00022	21.7	2.2	1	23	265	287	265	287	0.99
6	12	3e-06	0.00016	22.1	4.3	1	23	293	315	293	315	0.98
7	12	1.5e-07	7.9e-06	26.2	1.4	1	23	321	343	321	343	0.95
8	12	0.0044	0.23	12.2	3.5	1	23	349	371	349	371	0.98
9	12	1.5e-05	0.0008	19.9	2.1	1	23	377	400	377	400	0.97
10	12	9.5e-05	0.005	17.4	5.4	1	23	406	428	406	428	0.97
11	12	0.00037	0.019	15.6	2.0	1	23	434	458	434	458	0.97
12	12	0.00014	0.0072	16.9	0.7	1	23	465	489	465	489	0.97

Sequence Information

Coding Sequence: atggacCAAATAAGCGATTTGTGTAGATTGTGTGTCAGTGAAATAACGGAGAATCCTAAATCGCTGTTTGATTCACACATAGAACAAATTCCTGTAGTTGATGTCATCCGTAAATTCTGTTTTAGAATCACCGTACATAAAGATGACAAATTATCAAAGtatatttgtgaaaattgctATAATATACTACACAATGCTTATGATTTAAGTGAGAGAAGTGTTCAGTCAGAAAGAGAGCTTCATTTAATGTTATCAGATGTAATTATAAAGGAAGAACAAATCGATTTTGATGATGAGGATTACAAAGTTATGGTCCATGACGTTTCAATGGTCAAACCAGACATAGAACTTATAGAAGGCACCAATGCATTGGACGAGGAGGATGTTAAGGAAGAGAAGAAACCGAAACGAGTGAAAAAACATCAATGCAAAACTTgcttgaaaatgtttgaaaaaccATCGAAATTGGCCAGGCATGAAAAGACTCACGATGTCAACCGAAGACCATTTGCCTGTGATGATTGTTTTCAACGGTTCCAAACAGCTGAATCACTCGAAAGACATAAAATCATTCACTCTGgaatgacattaaaaattggacCAGACATTAAGGAATGGCCTTGCATAATGTGCGGAAAGGTATTTGATACACAGACAACAATGGCATCACATATGAGGATCCATAAAGATGAAATGGAAAAGCTTGAGTTTCCATGTAATTTATGCGATCGCGTCTTTCAGAAACTTAATGAGCTAACTAGACACTCGAGAACGCACGCAGAAAACAAGAACTACAAATGTCAAatttgttcaaaaatgttttctcaAGGATCACATCTAATTGACCACTTAAACCGTCACAACAATGTCCGACCACACGTTTGTCACGTATGCAACAAAGCATTTCAACAGTCATCAACCCTAAAGGATCATTTAAGGACACACAGTCAGGAAAAACCATTTTTGTGTAGCACCTGTGGCAAATCATTTAATAATCCTTCAAATCTTCGTCAGCACGTTAAGAGACACATGAACTTGAAGGAATTTGAATGTCATCTATGTCCTGGGAAGTTTTCCTGCAAAGCATCTCTTCAGTCGCACATAAGGTCACACGAAGGAATTAAAAGTCATACGTGTCAAATTTGTGGATCCTCATTTACAAAAGGAAGCTCACTTAAGAAACATGTACGGACCATACACGAAGGAATAAAAGAACATCCATGCTCGACATGTTCCATGAGATTCTCAAGTGCTGAACATCTCAAGAGACATTTTAGAACCCATAGTGGCGAAAAACCATACAAGTGCGACCATCCGAACTGTGACAAAGCTTACGCCCAATCGAATGACTTGTTGAAGCatagaaaattccatttgGGTGGAGAAAATGTCTACAAATGCACTTATGACAACTGCGATGAATCATTCAGATTGAAGAGCTTACTACGCGACCATTATGCAGTCCACAAGCAAGCATCCATTCCAGAAGAAGAAGATATGATTCCATGTGATTAA
Protein Sequence: MDQISDLCRLCVSEITENPKSLFDSHIEQIPVVDVIRKFCFRITVHKDDKLSKYICENCYNILHNAYDLSERSVQSERELHLMLSDVIIKEEQIDFDDEDYKVMVHDVSMVKPDIELIEGTNALDEEDVKEEKKPKRVKKHQCKTCLKMFEKPSKLARHEKTHDVNRRPFACDDCFQRFQTAESLERHKIIHSGMTLKIGPDIKEWPCIMCGKVFDTQTTMASHMRIHKDEMEKLEFPCNLCDRVFQKLNELTRHSRTHAENKNYKCQICSKMFSQGSHLIDHLNRHNNVRPHVCHVCNKAFQQSSTLKDHLRTHSQEKPFLCSTCGKSFNNPSNLRQHVKRHMNLKEFECHLCPGKFSCKASLQSHIRSHEGIKSHTCQICGSSFTKGSSLKKHVRTIHEGIKEHPCSTCSMRFSSAEHLKRHFRTHSGEKPYKCDHPNCDKAYAQSNDLLKHRKFHLGGENVYKCTYDNCDESFRLKSLLRDHYAVHKQASIPEEEDMIPCD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00319913;
90% Identity: iTF_00319913;
80% Identity: -