Basic Information

Insect: Chilo suppressalis
Gene Symbol: topi
Assembly: None
Location: chr20:16717496-16730702[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.008 0.46 10.8 1.8 2 23 56 77 55 77 0.96

2 12 0.017 0.98 9.7 1.6 2 23 84 106 83 107 0.92

3 12 0.017 0.97 9.8 0.2 2 23 114 136 113 136 0.90

4 12 0.00024 0.014 15.6 3.4 1 23 142 164 142 164 0.97

5 12 6.5e-07 3.8e-05 23.6 2.1 3 23 172 192 171 192 0.99

6 12 0.0012 0.072 13.3 2.1 1 21 198 218 198 219 0.93

7 12 0.0036 0.21 11.9 0.2 2 23 236 258 236 258 0.89

8 12 1.2e-05 0.00069 19.7 3.5 1 23 551 573 551 573 0.97

9 12 0.00052 0.03 14.5 2.6 1 23 580 603 580 603 0.94

10 12 0.0003 0.017 15.3 0.3 1 23 611 634 611 634 0.97

11 12 0.0025 0.15 12.4 3.9 1 23 640 664 640 664 0.97

12 12 9.1e-06 0.00052 20.1 0.7 1 21 670 690 670 691 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.008	0.46	10.8	1.8	2	23	56	77	55	77	0.96
2	12	0.017	0.98	9.7	1.6	2	23	84	106	83	107	0.92
3	12	0.017	0.97	9.8	0.2	2	23	114	136	113	136	0.90
4	12	0.00024	0.014	15.6	3.4	1	23	142	164	142	164	0.97
5	12	6.5e-07	3.8e-05	23.6	2.1	3	23	172	192	171	192	0.99
6	12	0.0012	0.072	13.3	2.1	1	21	198	218	198	219	0.93
7	12	0.0036	0.21	11.9	0.2	2	23	236	258	236	258	0.89
8	12	1.2e-05	0.00069	19.7	3.5	1	23	551	573	551	573	0.97
9	12	0.00052	0.03	14.5	2.6	1	23	580	603	580	603	0.94
10	12	0.0003	0.017	15.3	0.3	1	23	611	634	611	634	0.97
11	12	0.0025	0.15	12.4	3.9	1	23	640	664	640	664	0.97
12	12	9.1e-06	0.00052	20.1	0.7	1	21	670	690	670	691	0.95

Sequence Information

Coding Sequence: ATGGAACCCGTATCATATTTTAGCCTGCCAATTGTAGATTCCGAATCAACGGATTTAACTCTTAGAATAAGGTCCCATGAGGGTGGTTACGATGAGGTATTGGCACAATTCCTCTCTGGTGACGAGCCTCTGGAGGAACCTGACTTAAATGGACCAACTACACTGCACTGTGAAATTTGTCGTAAACAGTTCGATAATGCGAAAAAATACTATGGACATTTACGTGTGCATTCCAAAGACAATCTCTGGACCTGTGATCAATGTCCTGATCAAAGATTTTCAACAAAGCAACAATTGATGAAACATAGCCTGGTTCATCATCCTTTGGAACGTGTTTGGAGGTGCCCTCAATGTAGTATGGCATTTGAAACCCTGTGGCGGCTTCAACAGCATCTCTTTGCAAAACATTTAGACTACAGACCACATAAGTGTGATGTATGTGAAAAAGCCTTTCATAAATTGTCTGATCTCAAGAAACACAAAGCAGTCCATACTGATGAAAGAAAACATGGATGTACAGAGTGCACAATGAAATTTAAAGATAAATCTAATTTAAAAAGGCACATGCTGACACACAATAAAGAGAAACCATTTTGTTGTAATGGCTGTGGAAACAGATTTAAACAGATTGCATCTTTGAAGCGCCATAAACAAAATTGTTCTTATATAAAACATACTACAGAAGATAAGGCAATAAGGAAGAATTACTGTAAGGTTTGTGGGATGACATTCCAGTACAATAGTGCCTTATTGGAACATAGTGTGAGAGAACATTCTACAACATCAAACATTGAGAAATCTAATCAAATCACAATAGATACTAGGACTGAAGATAATATTGTAGATGACATTTTATCTGCAGAAGATGATTACATGACTATGTCTACACAAAATGGCCTTCTCAATGGGTACCATAGCATGCTACCAGAGCCACCTGTTAACAATATCACAGAGATGAATAATTTACATATGCTTGATGAAGAACTCCTTTATAGTGATATTGACTTTGAAAATTTTCCAAATAATCATATATTTAATATGAATACCAATGATATAGATTACAGTAGTACTGATAGAAGTGCAGAAATACAATTTGATCTTGCAGATTATGGTAGAAGTATAGATCAAGACATAATGAATGCACTTTATCACGCTAAAGCAGAAAATTTTCCTGATGAATTTTTAAATCATTCTGATGTGACCAATTTTACTGAGAAACCTGAGGATCTACTAGAAAATCCTACAGTCTCTGTAAATGAATGTGCTACAATTTTCGAAAGTGATGTGGATTTAGAAGCAAGTGCTAATTTAACTGCAAATTTAAATCAATTGATAGGAGACAATAATGTTCAATATATTTCAACAGAGGATGATGATACCTTTATAATTAGTTTAAAAAGTGAAATAGATGCTGAGCAATTGACTGATATGTTAAATATAGGCGTAGAGTTAGCAGAGGAGAACAACAAAACATCAGATGATTATAACACAGAAAGTTTATCTGATGTGGACAATTCTGAGAATGTAGTCTGTAGTGATGAACCTATAGTGATAAAAATCCAAGAGCCAGCAGAAAATGTGTCCTGTATTGCATCTTTTGAAAATGAAAATAAACAAGCAATGAAGACTAAAACAAAAAAGAAACTAATTTTTGCCTGTCGCCATTGTAATAAAGTTTTCAATAAAAGAGATAATTTTAAATCACATATAGCCACTCATGATTCGTCGCTACGTCGCCATAAGTGTTCGGTGTGTGAGGCGCGGTTCAGCTACCGCTCCACGTTGAACAAACACTTCGCATCTCTGCACGAACCGCGCGTGTGGAACGCTCATACCTGCGACATCTGTGATAAGCAGTATCGCGCTAATTGGATGTTGGTAGCCCACATTCAGCGAGATCACGATGGCTTAACACCGTATGAATGCGACAAAAAAGGTTGTGGAAAGAAGTTCTTCAAAAAATGTGACTTGGTTGTACATAAGAGGTATCATACCGGCGAGCGGCCGTACGCGTGCGAGGTCTGCCAGCGACGATTCCCTCACCCCTCGCACCTGAGGCGGCACGAGCGGGCCGTGGATTGTACCAAGTGGGCTAAAAAGTTTTAA
Protein Sequence: MEPVSYFSLPIVDSESTDLTLRIRSHEGGYDEVLAQFLSGDEPLEEPDLNGPTTLHCEICRKQFDNAKKYYGHLRVHSKDNLWTCDQCPDQRFSTKQQLMKHSLVHHPLERVWRCPQCSMAFETLWRLQQHLFAKHLDYRPHKCDVCEKAFHKLSDLKKHKAVHTDERKHGCTECTMKFKDKSNLKRHMLTHNKEKPFCCNGCGNRFKQIASLKRHKQNCSYIKHTTEDKAIRKNYCKVCGMTFQYNSALLEHSVREHSTTSNIEKSNQITIDTRTEDNIVDDILSAEDDYMTMSTQNGLLNGYHSMLPEPPVNNITEMNNLHMLDEELLYSDIDFENFPNNHIFNMNTNDIDYSSTDRSAEIQFDLADYGRSIDQDIMNALYHAKAENFPDEFLNHSDVTNFTEKPEDLLENPTVSVNECATIFESDVDLEASANLTANLNQLIGDNNVQYISTEDDDTFIISLKSEIDAEQLTDMLNIGVELAEENNKTSDDYNTESLSDVDNSENVVCSDEPIVIKIQEPAENVSCIASFENENKQAMKTKTKKKLIFACRHCNKVFNKRDNFKSHIATHDSSLRRHKCSVCEARFSYRSTLNKHFASLHEPRVWNAHTCDICDKQYRANWMLVAHIQRDHDGLTPYECDKKGCGKKFFKKCDLVVHKRYHTGERPYACEVCQRRFPHPSHLRRHERAVDCTKWAKKF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -