Cleg002421.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Chesias legatella
Gene Symbol
Zfx
Assembly
GCA_947359385.1
Location
OX375791.1:2634859-2658700[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 24 0.039 2.2 8.9 1.0 3 23 208 229 207 229 0.96
2 24 0.017 0.97 10.1 0.1 3 23 256 277 254 277 0.94
3 24 0.0037 0.21 12.2 0.6 1 23 299 321 299 321 0.97
4 24 0.0014 0.081 13.5 0.7 1 23 325 348 325 348 0.97
5 24 0.71 40 5.0 0.8 2 22 354 374 353 374 0.95
6 24 0.25 14 6.4 0.2 1 23 381 404 381 404 0.93
7 24 0.82 46 4.8 0.3 1 23 411 434 411 434 0.91
8 24 0.0008 0.045 14.3 2.1 2 23 440 461 440 461 0.97
9 24 6.6 3.7e+02 1.9 0.5 3 19 604 620 602 625 0.89
10 24 0.093 5.2 7.8 2.0 2 23 695 716 694 716 0.94
11 24 0.0015 0.082 13.4 0.2 1 23 720 743 720 743 0.93
12 24 0.12 6.6 7.4 0.3 1 21 747 767 747 768 0.94
13 24 0.0015 0.084 13.4 3.4 2 23 776 798 776 798 0.97
14 24 0.016 0.93 10.1 0.7 1 23 805 828 805 828 0.96
15 24 1.9e-06 0.00011 22.5 1.0 1 23 832 854 832 854 0.98
16 24 0.0006 0.034 14.7 0.1 2 23 869 891 868 891 0.96
17 24 0.36 20 5.9 0.1 3 21 897 915 896 916 0.96
18 24 0.6 34 5.2 0.2 2 23 950 972 949 972 0.90
19 24 0.26 15 6.3 3.1 2 23 1040 1061 1039 1061 0.89
20 24 1.5e-05 0.00086 19.7 0.4 1 23 1065 1088 1065 1088 0.97
21 24 0.11 6.2 7.5 1.3 1 21 1093 1113 1093 1114 0.93
22 24 0.053 3 8.5 0.3 1 23 1121 1144 1121 1144 0.94
23 24 0.007 0.39 11.3 4.6 1 23 1151 1174 1151 1174 0.96
24 24 0.0066 0.37 11.4 1.0 1 20 1179 1198 1179 1200 0.94

Sequence Information

Coding Sequence
ATGGATGGGAAAGCGTCCGATTGGAGGCCGGGCCCGACCGTGTGCCGATGCTGCCTCACCGAAGGATGCTACAAGGACATATCCACAGAATATTTCTGGATGGGAAAGCGGGAGGTTTACGCCGAAATGCTCAAAGAGACCCTCGACGTTACCATTGCTTATTCCCAATCGGGAGGTCCCAACAGCAACAGTCGGCTGATCTGTGAGCCGTGCATCTCCCGGCTGCGGGATGCCACCGAGTTCAAGAGGCAGGTCATAGACTGCGAGAAGACATTCATGCACCACTTGGACGGGGGCAGTGCCAGCGGTTCTCATGTTGATGACCAACCGCTAACTAAACTTGCAAGCAAAGTCCCCAAAAAGGAAGCGGTCGATCTGTTAGACCTATTAGACAACTCTCAAATAACGGTCAAGCGTAAACCCACTGTTAAGATGAAGGAACCACCTGCGAAGAAGGTCAAGAAAAAGGAGATTGTATCCAAGCCTTCAGCCAGCAAGGTTGCTGCTATGAAGAAAAATGAAAAGAAAAAAGCGTTAAACGATCCATCGCGCGGTAACGCCGAGTTGATACTGCGGTGGACTACCGCATGCCCGTTCAGAGTCAACGATAAGTCTATACTGTGCGTTTACTGCCACGAGCTGTTCGAGGATCCGGCCGCGTTCCGTCACCACGTGCGGCAGGATCACGAAAATTGCACCCTAGAGGTCGTCTTCTACAACCTGCCCAAGTCCGAGTTCATCAAGGCCGATCTCACAGACCTCGCATGCAGAATCTGTTCCGAAACCTTCAGAGATCTGGACTCTATCGCGGCCCACCTCTCGTCCCAACACAACAAACGCATAGACTTCAGCGGCAAACTCGGCGTGATGCCGTACAGACTCAAAAAAGACTCGTTCAACTGCGCCGTATGCGACAAAAACGTACCCTCCCTCCTCCATCTCAACCGGCACACGATAACGCACTTCCTCAGTTTCGTGTGTCACGTGTGCGGCAGCAGCTACATAGCGTCGACCGGTCTCCTGAGGCACCTCCGCTCGAAGCACCAGGACTACGAGGTATACTGCAAGCGGTGTCGCACCAAGTTCCCCAGTATGGAGGCGAAGGAGCGACACAGGCGCACGGTCAAAAGCTGCATGCCGTACGCGTGCCCGACTTGCGCGGAGCGTTTCCTCGATTGGAAGACGCGCCAGAGGCACATGGAGGCTCAACACGGTATCGCGAAGAAGACATACCGTTGCGCCGATTGCAACGTCGATTTCCCCAGCGACGTTGCGTATTACAGTCACTTCAAGCTGCAGCACTCTGACAACTGTGCTGTGTGCAAGCACTGCGGTATGAAATTCGTGTCGGTGTACCGTTTGAAGCGACATCTCGCTAAGCATAACATCGCGGCGGTTGATTCGAATCGGATACCGAATAATATTACATTGGATGTGATGAGAGCGAAACGCCGCAACACCGAAGGCGAATGGCCGTCGGTCACAAAAGCAAATGAGATTGAAATCACCAGTGATATAAAAGACGATTCGTCTAAAAGCCAGTTAAACTATGAAAGGATAGTTTCGGACAAGGAATACCGAATTCGCAATAGAGAAGGAAGTATCGGAACTATCGGGAAACCAATCCTTGTACCTCGGAACGATGAGGTTATTGATAAATCGACGAAAACCTCTTTTGTTCATACTAACGCAAAAAAAGAGTTATGTATCCAACAGCCAGAGCCAACATTTTTGCAGAACGCTCGACTTTTGCTCACGCACACGACAGTAATCCCGCACAGAATGGAGAACGCCAACTCACAGATACCTTGCTATGCGTGTGAAAGCAAATTCAAAGATCCAAATTTGCTCAGAGACCACTGCCTCGCTGAACATAAAAACGCCGATAAGACACGAGGCATGAACCTGTTTAAGATCCAAACACGTGCGGACATCACCGATTTGGCGTGCGTTATGTGCGCGCAACCATTCGACTCATTGGAGGAGGCGGCTACGCACCTCGTCCGAACTCACCAGATCGACATTAACCTCCAAGACAGGCTAGGGCTGGTACCCCTTAAATTTACCCAAAGAGGCGTCCTAGTTTGCGTCGTGTGCCAAAGAAAATGCAGCACATACCGGGAACTGTACCGGCACTCGGGCACGCACTACCACCTGCACGTCTGCGAGATATGCGGCCGACCGTTCGAGTCGGCACGGTCGGTGAGAGTGCACGTGCTGCAGCGTCACGTGCAGGGGCACAGGTGTAAGTCGTGCCGCGTCGTGTTCCCGACCGTGCTCGAACTGCGGCGCCACGTCAAAGAGAGCGACCGGTGCGCGCCGGCCCGCTGCAAGACCTGCAACAAATCTTTCCGTTGCTGGGAGGCGCTGCAACGCCACCGGGAAACCGCCCACGGGATACAGAAGAGGGTTTACGATTGTTCGGAATGCTTGCAGGTGTTTCAGACGCGTGCGAGTCTGTACACGCATTTCAATAGAGCCCACACGGATCAGTATAaatgcgagcattgcggcaagagttttggcgaggcgcagagtttgaggaggcacttgttggttcacaccggcgagaggccgcacgcatGTTCGTATTACTACCTTCAGGTATGCGAGATTTGTGGTAAAAAATTTGGCTCCCTCGATGGTTTGCGGGGGCACAAATTGACGAGCCACGTGGACGGTCACGGCTGCAACAGCTGCAAAGCAGTTTTCCCCTCAAAACTAAAGTTGAAGGAACACGTTAGAGACGAATTGAAATGGCCGACAGTGCCCACGACGAAGCGCAACGCGGAGATAATCGTGAGACATTCGACAGTGTACCCGTTCAGACTGCCGGAGAACTGTATGGTGTGCGTGTTCTGTTGCGAAGGTTACGAGGACCCATCCGCGTTTAGGAAACACATGGACGTAGAACATCAGACGTTTTCACTGAGAATGGCGTTCGCTCATTGCCACGAGGGGTTCATAAAGGCAGATTGCACCGACGTAAGGTGTCGCATCTGCTTCCAAACGTGCCACGGCCTAGACGAGATCGCTGTACACTTGCGTAAGAAACACGCCAAACCCGTGGACCTAACGTCGCCGTTAGGGATCCAACCTTTCAAACCGGACAAACTGAAATGCGCGTTGTGCGACTCCAAGTCCTTCAGTTTGCGACACCTAAGCCGACACACCCAAACACACTTTCGAAGGTTCACTTGTGAGTCTTGCGGTAAATCCTACGCCACGAACACAGCGTTGCAAGTACACATTAAATATTCGCATCTGATCAAAGAACATTATTGTAGAAAATGCAAAACTAAATTCGTTTCGTCTGATGCGAAGCGAGCTCATTTGCAGGAGTCTACTAGGTGCTGGTTGTATTTGTGTAATATGTGTGGCGATAGGTTCATATCTTGGAATACGAAGCAACTGCATATGAAGGAGGCTCATGGTGTGCCGGAGGAACCCCACGTTTGTCCTGAATGTGGCATGGTGTTCACAGACAAGAAGGCGTGTCGTCACCACTTTAGGATAAACCATACCGATGATAACTTTGTCTGTTCCTTCTGCGGTCTCAAGTTTGCTACCAAGAAGTACTACGAAGAGCACAGAACTCGGAATTATCGTTTGTATCCGCAACAGCGGTGA
Protein Sequence
MDGKASDWRPGPTVCRCCLTEGCYKDISTEYFWMGKREVYAEMLKETLDVTIAYSQSGGPNSNSRLICEPCISRLRDATEFKRQVIDCEKTFMHHLDGGSASGSHVDDQPLTKLASKVPKKEAVDLLDLLDNSQITVKRKPTVKMKEPPAKKVKKKEIVSKPSASKVAAMKKNEKKKALNDPSRGNAELILRWTTACPFRVNDKSILCVYCHELFEDPAAFRHHVRQDHENCTLEVVFYNLPKSEFIKADLTDLACRICSETFRDLDSIAAHLSSQHNKRIDFSGKLGVMPYRLKKDSFNCAVCDKNVPSLLHLNRHTITHFLSFVCHVCGSSYIASTGLLRHLRSKHQDYEVYCKRCRTKFPSMEAKERHRRTVKSCMPYACPTCAERFLDWKTRQRHMEAQHGIAKKTYRCADCNVDFPSDVAYYSHFKLQHSDNCAVCKHCGMKFVSVYRLKRHLAKHNIAAVDSNRIPNNITLDVMRAKRRNTEGEWPSVTKANEIEITSDIKDDSSKSQLNYERIVSDKEYRIRNREGSIGTIGKPILVPRNDEVIDKSTKTSFVHTNAKKELCIQQPEPTFLQNARLLLTHTTVIPHRMENANSQIPCYACESKFKDPNLLRDHCLAEHKNADKTRGMNLFKIQTRADITDLACVMCAQPFDSLEEAATHLVRTHQIDINLQDRLGLVPLKFTQRGVLVCVVCQRKCSTYRELYRHSGTHYHLHVCEICGRPFESARSVRVHVLQRHVQGHRCKSCRVVFPTVLELRRHVKESDRCAPARCKTCNKSFRCWEALQRHRETAHGIQKRVYDCSECLQVFQTRASLYTHFNRAHTDQYKCEHCGKSFGEAQSLRRHLLVHTGERPHACSYYYLQVCEICGKKFGSLDGLRGHKLTSHVDGHGCNSCKAVFPSKLKLKEHVRDELKWPTVPTTKRNAEIIVRHSTVYPFRLPENCMVCVFCCEGYEDPSAFRKHMDVEHQTFSLRMAFAHCHEGFIKADCTDVRCRICFQTCHGLDEIAVHLRKKHAKPVDLTSPLGIQPFKPDKLKCALCDSKSFSLRHLSRHTQTHFRRFTCESCGKSYATNTALQVHIKYSHLIKEHYCRKCKTKFVSSDAKRAHLQESTRCWLYLCNMCGDRFISWNTKQLHMKEAHGVPEEPHVCPECGMVFTDKKACRHHFRINHTDDNFVCSFCGLKFATKKYYEEHRTRNYRLYPQQR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-