Basic Information

Insect: Cheilosia vernalis
Gene Symbol: L
Assembly: GCA_949126925.1
Location: OX421362.1:55704146-55721523[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 5.2e-06 0.00066 20.8 1.7 1 23 222 244 222 244 0.98

2 15 0.44 55 5.3 5.8 1 23 250 272 250 272 0.98

3 15 2.3e-07 2.9e-05 25.1 3.1 1 23 278 300 278 300 0.99

4 15 1e-05 0.0013 19.8 0.3 1 23 306 328 306 328 0.98

5 15 1.7 2.1e+02 3.5 0.3 3 23 392 414 390 414 0.87

6 15 0.0039 0.49 11.8 0.4 2 23 431 453 430 453 0.97

7 15 0.019 2.4 9.6 1.4 1 23 534 556 534 556 0.97

8 15 0.001 0.13 13.6 1.0 2 23 564 585 563 585 0.95

9 15 0.00034 0.043 15.1 1.3 1 23 593 618 593 618 0.91

10 15 0.0014 0.17 13.2 2.9 1 23 710 732 710 733 0.96

11 15 0.00099 0.13 13.6 4.6 2 23 915 937 914 937 0.96

12 15 0.12 15 7.1 0.1 1 23 943 965 943 965 0.92

13 15 9.4 1.2e+03 1.1 0.5 2 23 973 994 973 994 0.93

14 15 0.019 2.4 9.6 0.0 1 23 1114 1136 1114 1136 0.95

15 15 0.044 5.6 8.4 1.2 1 23 1143 1165 1143 1165 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	5.2e-06	0.00066	20.8	1.7	1	23	222	244	222	244	0.98
2	15	0.44	55	5.3	5.8	1	23	250	272	250	272	0.98
3	15	2.3e-07	2.9e-05	25.1	3.1	1	23	278	300	278	300	0.99
4	15	1e-05	0.0013	19.8	0.3	1	23	306	328	306	328	0.98
5	15	1.7	2.1e+02	3.5	0.3	3	23	392	414	390	414	0.87
6	15	0.0039	0.49	11.8	0.4	2	23	431	453	430	453	0.97
7	15	0.019	2.4	9.6	1.4	1	23	534	556	534	556	0.97
8	15	0.001	0.13	13.6	1.0	2	23	564	585	563	585	0.95
9	15	0.00034	0.043	15.1	1.3	1	23	593	618	593	618	0.91
10	15	0.0014	0.17	13.2	2.9	1	23	710	732	710	733	0.96
11	15	0.00099	0.13	13.6	4.6	2	23	915	937	914	937	0.96
12	15	0.12	15	7.1	0.1	1	23	943	965	943	965	0.92
13	15	9.4	1.2e+03	1.1	0.5	2	23	973	994	973	994	0.93
14	15	0.019	2.4	9.6	0.0	1	23	1114	1136	1114	1136	0.95
15	15	0.044	5.6	8.4	1.2	1	23	1143	1165	1143	1165	0.94

Sequence Information

Coding Sequence: ATGATGGCCTTAAAAATGCTTTACCGTGGCCCCAGCTCTAGGTTGGAGAATTTAATCGAAAAGATTCAAGCTACTAAAGAAGTGAACACAGATCTGTACTCCACGCACACCTCGTCCAGCTACTCGCCGTCCATGTCGGATGGGACAATTACTCCGAACTCGTTgcacaaccaccaccaccaccaccacagcCAGCAgaaccaccatcatcatcatcttcaacGACTGCATCACTTGCAGTACCAGTGCGAACAACAGCACAACAGCGGTGGTCACAATCGCGACAGTAGGCATCACAATCGACGTGTTTCAGCCATAAATGGAGCAACTGGCACCGGTGTTGGTGATGGGGACGGGAATGACGaggacgacgatgatgacgacggGGACATCAGGGACGAAGATGACGACGCCGCAAATTCTAGCGAGGAAAGGGTTTTCCTCTCAGCGAACGGTGGTGGTGCCAACGATGCCgccaacaccaccaccaccaccaacaccaccGCCGCCACCGCCGCTGCCATCACCACCATCAGTGGCGCAATCGGCGAACATTCCATGAAAATTCCAACGAAATTGCGGAAAATCGATAGGGATTCGGCAAAGTTGTTGGATAAGTTGACAAGTGATGGCATTAAGAGCGCGACCGACCGCGACGGATCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGCCTTGGGTATCTGAAGAAGCATGAACAGAGCCACGCGGAGCATCTCCCATTCAAGTGCGACTACTGTGCACGGCTTTTCAAGCACAAAAGGTCGCGTGACCGGCACACCAAGCTGCATACCGGGGATAGGCGGTACAGATGTCCACACTGCGAAGCTGCATTTTCGCGAAGTGATCATCTAAAGATCCACATGAAAACCCACGACAACCAGAAACCGTTTCAGTGCACCATCTGCAACCGTGGCTACAACACAGCGGCGGCTCTGACGTCTCACATGCAAAACCACAAAAAGCAGGCAGCTCTGCTCGCCGCTGGGGGTAACCCCACGGCACTTAATTACAGCCCCCGTTCAACAGGATCCGGTTCGAGTAATGGAAGTCTGCAGAAACGCCGATATGCCTCGGTGGCCAACACCAAGAGTCCCAGCCCAAGCACAATGGACTACGCGAAGCGAGTGCGCAGCTCTATTGTCTCGTGCATGTACTGCACTAAGTCGGATTTCGCATCAATGGAGCAGCTTAGCAGTCACATACAAACCATGCATGAGAAGGAGGCACAGGCCAATCAGCCCGCCACCAGTGGCTTTCAGATGTCCTGCGAGTATTGCACAATGAAGTTCCCCAGCATACCGGCAATGTTCCAGCACATGAGAACCACACACATTGATCGTCTGTCCAGTCCGACGAGCTACTTTGAGCACTTTAACCGGCTGGCGGCTTCGGGTACGTTTAGTCCCCGTCTGCCAACACCCAAGCCGCATGAGACAAAGGTGAAGGTCGAAGAACCGAGTCCCAAGGAGTTGGAGAAACCGGACGACGAACCTACAGATTTGAGCCAAAACAAGCGCTCCGCCCAGACACCGTCTCAGGAGTCTGCCGAAGCCGTGGAGAAACCCGGGGTGTTCTTCTGTAATCAGTGCAACGACGGATTTCCAGATTTTGACAGCTTCCGCAACCATCTTAAGTCGCACATCGTGCAGGGCCTGAACTTGGTGTGCCACCACTGCGGACAGTCATTGCGCGACCAGCCCGAGTACGAACGGCATGTGGTTTCCCATTTCCTGATAACGAGCGTGGAATACAGCTGCACTGAGAAAAACTGCAGTAAGACGTTCTCTAAGCCGGAGGAGCTGCAAAAGCACCTCTTTGACAGCCACCTTCAGACGATGTACAAGTGCCTGCTGTGCTCGGATCTATTCGAGACAAAGGTAGCGATTCAAGTGCACTTCGCTTGCATACACTCGCCGGAGAGTAAGGTGTTCCGATGTTCGGCGTGCATGGACACATTCCACGGAGAGCAGGAGTTCCATATCCATGTGAAGACCCGCCATCAGACGATAGTCGGCTCGCCCATACAGTGCATGTTCTGCAGGGCGGTTTGCTCCACAGAGCTGGAGATGCACTTTCATCTGGCTGCGCATGCGCGACAATTCCGCTGTCCATCATGCCCGGAAACGTTTCATGTGGAGTTTCTGCTTGACCGTCACATGCAGACTCACCATCACGGCCAAAAGGATGTCGATTCGGTGCCCGTTGTCAGTTCGCCAATCAATCCCATCTACATGAGCGCCCTCTTCAATAAGCCACCACCCTCGACCCAGAACAATAACAACAGCGTTCTGGATTACAACGCCTTCGCCATCGGAAAGAACCTGTTCGCCAATGCCGCAGGGAATACGAGTAAGTTCTACAATCCGCTGCAGGTGGACACGAGTTCCACGATGAAGCATCCCTCCCTAGTGTACGCCAGCTTAAACCAGCGCTACTTCGACACCAACCGGACTATTCTCGAGATGTATAACCAGCACCAGCAGGAAAAGATTAGCGGAGTGACAAACTACTTTAACAGCccgaacaacaacaataacaacaacagccGGAGCGCTCCTAAGCCTCAGCAGGAAGGCAACAAACCGACGGAACGAGCTATAGGCGGCGGTGGTGGTTTCAGCTGTGGCATGTGTGAACGTAACGACTTCCGAACTGAGGCCGAGATTCATTCCCACCGCAAGATCGTTCACAATCTGAAGACCGGGGTAAGTCTTCGCTGTGCCTACTGCAGCGGTAACTTTAAGTCTCGCAGCGAGCTGGAGCACCACATGAAGACGTGCCACAACTCGACAGGGAAGCACAAATGCCTCATTTGCGACGAGATCTTCCCCTCCCCCGCTATCCTCGCCGAGCACAAGCTGCAACACTCCAAAGTGGGGCAGTCCGGCAAGTGTTCGCACTGCGCTCACGCCCTGGCAGACGTGGCTGCCTTCAAGGGCCATCTGTTGGAGCACAACACCGAGGGCCAGATGCCGGTTCAGTGCATTTGCTGCCGCCAAACGCTTCACTCCGACTTTGAGATCGGCCTGCACGCCAAGTTCCACACAAAGTCTTCATCCGTCTCGGAGAGTGCGTGCGCTCTGTGCCTGGAAACCATACCCAACACAGCAGACGCCAAGGTATGCGAGAAATGCTGTCGCAAACACAACTTGAGCTCCAAGTTCAACAACCAGCGGAACTTCGAAAGCAGTTCGGGTCCATCGAACTACGTGGAGAACCGGTGCAACCTGTGCAAGGTCATCATGCCGCatgcccaaaaactccaagagCACCTGGTCGAGCACACCTTCGCCGGCTGCGAGGACCGAGGCTTTATTTGCTACATCTGCTCCGCGGTCTTCACAGCGCCCGGTGGTCTGCTGAGTCACATGGCCGATCACGGTGCCAACGCACGCCCCTACGACTGCAACCTTTGCAGTGAAAAGTTCTACTTCCGCGCGGAGTTGGATCACCACCTGGTTGAGCACGAGGCAAGAGGTCGCCTGAAGAATGCTAGCGCCGGTGAGGCGAACACACTCCCTGAAGTCAAGAAGCCTTTTGAAGAGCCTCCGCCAGCACAGGAGGCAACTCCCAAGCTGGAACTGAAGAACGAGATCGTTGACGAAAAACCATCAGCCGCCGCCGACGAGGACGACGACGAGTATATTGAAGTGGAAAAGGTACCGGAAGTCCCACTGGACACTGCCCCCCAAGAGGACTAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEVNTDLYSTHTSSSYSPSMSDGTITPNSLHNHHHHHHSQQNHHHHHLQRLHHLQYQCEQQHNSGGHNRDSRHHNRRVSAINGATGTGVGDGDGNDEDDDDDDGDIRDEDDDAANSSEERVFLSANGGGANDAANTTTTTNTTAATAAAITTISGAIGEHSMKIPTKLRKIDRDSAKLLDKLTSDGIKSATDRDGSYQCQFCDKSFPRLGYLKKHEQSHAEHLPFKCDYCARLFKHKRSRDRHTKLHTGDRRYRCPHCEAAFSRSDHLKIHMKTHDNQKPFQCTICNRGYNTAAALTSHMQNHKKQAALLAAGGNPTALNYSPRSTGSGSSNGSLQKRRYASVANTKSPSPSTMDYAKRVRSSIVSCMYCTKSDFASMEQLSSHIQTMHEKEAQANQPATSGFQMSCEYCTMKFPSIPAMFQHMRTTHIDRLSSPTSYFEHFNRLAASGTFSPRLPTPKPHETKVKVEEPSPKELEKPDDEPTDLSQNKRSAQTPSQESAEAVEKPGVFFCNQCNDGFPDFDSFRNHLKSHIVQGLNLVCHHCGQSLRDQPEYERHVVSHFLITSVEYSCTEKNCSKTFSKPEELQKHLFDSHLQTMYKCLLCSDLFETKVAIQVHFACIHSPESKVFRCSACMDTFHGEQEFHIHVKTRHQTIVGSPIQCMFCRAVCSTELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQTHHHGQKDVDSVPVVSSPINPIYMSALFNKPPPSTQNNNNSVLDYNAFAIGKNLFANAAGNTSKFYNPLQVDTSSTMKHPSLVYASLNQRYFDTNRTILEMYNQHQQEKISGVTNYFNSPNNNNNNNSRSAPKPQQEGNKPTERAIGGGGGFSCGMCERNDFRTEAEIHSHRKIVHNLKTGVSLRCAYCSGNFKSRSELEHHMKTCHNSTGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCSHCAHALADVAAFKGHLLEHNTEGQMPVQCICCRQTLHSDFEIGLHAKFHTKSSSVSESACALCLETIPNTADAKVCEKCCRKHNLSSKFNNQRNFESSSGPSNYVENRCNLCKVIMPHAQKLQEHLVEHTFAGCEDRGFICYICSAVFTAPGGLLSHMADHGANARPYDCNLCSEKFYFRAELDHHLVEHEARGRLKNASAGEANTLPEVKKPFEEPPPAQEATPKLELKNEIVDEKPSAAADEDDDEYIEVEKVPEVPLDTAPQED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01542500;
90% Identity: iTF_00314731;
80% Identity: -